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Author : Harold Varmus,Robert Allan Weinberg
Publisher : Times Books
Page : 214 pages
File Size : 48,6 Mb
Release : 1993-01-01
Category : Medical
ISBN : 0716750376
Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells
Author : Harold Varmus
Publisher : Unknown
Page : 214 pages
File Size : 49,5 Mb
Release : 1996
Category : Cancer cells
ISBN : OCLC:641160996
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 42,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : Weinberg, Robert A.
Publisher : W.W. Norton & Company
Page : 6 pages
File Size : 44,9 Mb
Release : 2013-05-24
Category : Science
ISBN : 9780815345282
Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.
Author : Lauren Pecorino
Publisher : Oxford University Press
Page : 365 pages
File Size : 53,7 Mb
Release : 2012-04-26
Category : Medical
ISBN : 9780199577170
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
Author : Stella Pelengaris,Michael Khan
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 42,9 Mb
Release : 2009-03-12
Category : Science
ISBN : 9781444309089
This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field
Author : Fiona Macdonald,Christopher Ford,Alan Casson
Publisher : Garland Science
Page : 269 pages
File Size : 47,9 Mb
Release : 2004-01-15
Category : Science
ISBN : 9780203503447
Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.
Author : Robert A. Weinberg
Publisher : Garland Science
Page : 960 pages
File Size : 44,9 Mb
Release : 2013-05-15
Category : Science
ISBN : 9781317963462
Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world.The Biology of Cancer is a textbook for students studying the molecular and cellula
Author : Stanton L. Gerson,Edmund C. Lattime
Publisher : Elsevier
Page : 534 pages
File Size : 42,9 Mb
Release : 2002-04-04
Category : Science
ISBN : 0080491367
The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene therapy using immune, oncogene, antisense, pro-drug activating, and drug resistance gene targets, while other chapters discuss therapeutic approaches and clinical applications. This book is a valuable reference for anyone needing to stay abreast of the latest advances in gene therapy treatment for cancer. Key Features * Provides in-depth description of targeted systems and treatment strategies * Explains the underlying cancer biology necessary for understanding a given therapeutic approach * Extensively covers immune therapeutics of vaccines, cytokines, and peptide-induced responses * Presents translational focus with emphasis on requirements for clinical implementation * Incorporates detailed illustrations of vectors and therapeutic approaches ideal for classroom presentations and general reference
Author : B.A. Ponder,M.J. Waring
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401106771
It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
Author : Francesco Pezzella,Mahvash Tavassoli,David Kerr
Publisher : Oxford University Press
Page : 505 pages
File Size : 53,5 Mb
Release : 2019-05-02
Category : Medical
ISBN : 9780198779452
The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.
Author : Fred Bunz
Publisher : Springer
Page : 343 pages
File Size : 54,6 Mb
Release : 2016-03-01
Category : Medical
ISBN : 9789401774840
This is the second edition of a widely used textbook that consolidates the basic concepts of the cancer gene theory and provides a framework for understanding the genetic basis of cancer. Particular attention is devoted to the origins of the mutations that cause cancer, and the application of evolutionary theory to explain how the cell clones that harbor cancer genes tend to expand. Focused on the altered genes and pathways that cause the growth of the most common tumors, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff. For students with a general interest in cancer, this book provides a highly accessible and readable overview. For more advanced students contemplating future study in the field of oncology and cancer research, this concise book will be useful as a primer.
Author : P.R. Burch
Publisher : Springer Science & Business Media
Page : 456 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401166034
Of all the diseases that afflict mankind those described as 'cancer' evoke the strongest emotions. 'Cancer' connotes pain, protracted suffering, hideous growth and death. It is widely and justifiably feared. In medically advanced countries, malignant neoplasms (the official term for cancers) account for a substantial proportion of all deaths. Out of a total of 575194 deaths in Eng land and Wales during the year 1970, some 117076-or 20·4 per cent-were attributed to neoplasms of one kind or another (Registrar General, 1972). Diseases of the circulatory system-mainly arteriosclerotic and degenerative heart disease-claimed many more victims, being responsible for some 50·6 per cent of all deaths, but our psyche evidently responds more to the manner of the disease than to the number of deaths it causes. Many of us will have witnessed the deterioration of a close friend or relative suffering from an inoperable cancer: such an experience induces a sense of hopelessness and helplessness. The feelings of sorrow and distress can be a powerful stimulus to action and they often result in dedicated and tireless research efforts. At the same time, the very strength and depth of the commitment may sometimes be incompatible with the detachment that is needed for objective analysis and a wise strategy. Not too rigorously, we reason that if only we can discover the causes of cancer, then our problems will be solved and our agonies relieved. Remove the cause: prevent the cancer. The logic exerts an irresistible appeal.
Author : Howard D. Lipshitz
Publisher : Springer Science & Business Media
Page : 557 pages
File Size : 49,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781441989819
- For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume - Papers are organized into sections that reflect the focus of the research - Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers
Author : Institute of Medicine,Committee to Review the Department of Defense's Breast Cancer Research Program
Publisher : National Academies Press
Page : 150 pages
File Size : 49,7 Mb
Release : 1997-07-31
Category : Medical
ISBN : 9780309174565
According to current statistical data, one in eight women will be diagnosed with breast cancer. The five-year survival rate for breast cancer patients has improved in recent years, but the overall mortality rates have changed little. In 1993 Congress allocated $210 million for breast cancer research as part of the Department of Defense budget. An Institute of Medicine (IOM) committee was convened at that time to advise the U.S. Army Medical Research and Development Command on strategies for managing a breast cancer research program. This book evaluates the program's management and achievements to date. Although it is too early to evaluate the program in terms of breakthrough results and new insights produced by the funded projects or investigators, this book documents the process used to select research proposals for funding and analyzes the portfolio of funded projects in terms of their responsiveness to the recommendations and fundamental questions articulated in the 1993 IOM report.