Genes Brain Function And Behavior

Author : Douglas Wahlsten
Publisher : Academic Press
Page : 300 pages
File Size : 50,8 Mb
Release : 2019-03-01
Category : Science
ISBN : 9780128128329

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Genes, Brain Function, and Behavior by Douglas Wahlsten Pdf

Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources

Author : Deborah Finkel,Chandra A. Reynolds
Publisher : Springer Science & Business Media
Page : 300 pages
File Size : 45,7 Mb
Release : 2013-07-09
Category : Psychology
ISBN : 9781461474470

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Behavior Genetics of Cognition Across the Lifespan by Deborah Finkel,Chandra A. Reynolds Pdf

Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an especially advantageous moment to produce a work that presents a collection of the groundbreaking research on cognitive abilities across the lifespan. This volume presents an overview of the current state of quantitative and molecular genetic investigations into the many facets of cognitive performance and functioning across the lifespan.​

Author : Robert T. Gerlai
Publisher : Academic Press
Page : 710 pages
File Size : 40,6 Mb
Release : 2018-04-24
Category : Mathematics
ISBN : 9780128041161

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Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by Robert T. Gerlai Pdf

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

Author : Anonim
Publisher : Elsevier
Page : 376 pages
File Size : 50,5 Mb
Release : 2011-04-21
Category : Science
ISBN : 9780444538857

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Gene Expression to Neurobiology and Behaviour by Anonim Pdf

How does the genome, interacting with the multi-faceted environment, translate into the development by which the human brain achieves its astonishing, adaptive array of cognitive and behavioral capacities? Why and how does this process sometimes lead to neurodevelopmental disorders with a major, lifelong personal and social impact? This volume of Progress in Brain Research links findings on the structural development of the human brain, the expression of genes in behavioral and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language, in an attempt to answer these questions. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Author : National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Publisher : National Academies Press
Page : 610 pages
File Size : 45,5 Mb
Release : 2000-11-13
Category : Social Science
ISBN : 9780309069885

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From Neurons to Neighborhoods by National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development Pdf

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Author : Robert R.H. Anholt,Trudy F. C. Mackay
Publisher : Academic Press
Page : 345 pages
File Size : 48,6 Mb
Release : 2009-09-21
Category : Psychology
ISBN : 9780080919898

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Principles of Behavioral Genetics by Robert R.H. Anholt,Trudy F. C. Mackay Pdf

Principles of Behavioral Genetics provides an introduction to the fascinating science that aims to understand how our genes determine what makes us tick. It presents a comprehensive overview of the relationship between genes, brain, and behavior. Introductory chapters give clear explanations of basic processes of the nervous system and fundamental principles of genetics of complex traits without excessive statistical jargon. Individual chapters describe the genetics of social interactions, olfaction and taste, memory and learning, circadian behavior, locomotion, sleep, and addiction, as well as the evolution of behavior. Whereas the focus is on genetics, neurobiological and ecological aspects are also included to provide intellectual breadth. The book uses examples that span the gamut from classical model organisms to non-model systems and human biology, and include both laboratory and field studies. Samples of historical information accentuate the text to provide the reader with an appreciation of the history of the field. This book will be a valuable resource for future generations of scientists who focus on the field of behavioral genetics. Defines the emerging science of behavioral genetics Engagingly written by two leading experts in behavioral genetics Clear explanations of basic quantitative genetic, neurogenetic and genomic applications to the study of behavior Numerous examples ranging from model organisms to non-model systems and humans Concise overviews and summaries for each chapter

Author : Jonathan Flint,Ralph J. Greenspan,Kenneth S. Kendler
Publisher : Unknown
Page : 387 pages
File Size : 45,9 Mb
Release : 2020-01-23
Category : Electronic
ISBN : 9780198716877

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How Genes Influence Behavior 2e by Jonathan Flint,Ralph J. Greenspan,Kenneth S. Kendler Pdf

How Genes Influence Behavior takes a personal and lively approach to the study of behavioral genetics, providing an up-to-date and accessible introduction to a variety of approaches and their application to a wide range of disorders, and modeling a critical approach to both methods andresults.This second edition includes additional biology content to help students understand the biological foundations of the field, while maintaining an appropriate focus on the main issues of relevance to psychology students; updates coverage of genomic technologies and their applications; and covers awider range of disorders, including autism spectrum disorder, eating disorders, and intellectual disability. A new final chapter guides students through a range of quantitative approaches using worked examples that relate directly to cases and examples used earlier in the text, and addresses currentissues arising from debates around reproducibility.The online resources that accompany this book include:For students* Multiple choice questions for students to check their threshold knowledge* Data sets for students to manipulate, so that they can apply what they have learnedFor lecturers* Figures and tables from the book, ready to download

Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 90 pages
File Size : 51,5 Mb
Release : 2008-12-07
Category : Science
ISBN : 9780309120920

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From Molecules to Minds by Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Neuroscience has made phenomenal advances over the past 50 years and the pace of discovery continues to accelerate. On June 25, 2008, the Institute of Medicine (IOM) Forum on Neuroscience and Nervous System Disorders hosted more than 70 of the leading neuroscientists in the world, for a workshop titled "From Molecules to Minds: Challenges for the 21st Century." The objective of the workshop was to explore a set of common goals or "Grand Challenges" posed by participants that could inspire and rally both the scientific community and the public to consider the possibilities for neuroscience in the 21st century. The progress of the past in combination with new tools and techniques, such as neuroimaging and molecular biology, has positioned neuroscience on the cusp of even greater transformational progress in our understanding of the brain and how its inner workings result in mental activity. This workshop summary highlights the important issues and challenges facing the field of neuroscience as presented to those in attendance at the workshop, as well as the subsequent discussion that resulted. As a result, three overarching Grand Challenges emerged: How does the brain work and produce mental activity? How does physical activity in the brain give rise to thought, emotion, and behavior? How does the interplay of biology and experience shape our brains and make us who we are today? How do we keep our brains healthy? How do we protect, restore, or enhance the functioning of our brains as we age?

Author : Paul R. McHugh,Victor A. McKusick
Publisher : Unknown
Page : 251 pages
File Size : 48,5 Mb
Release : 1991-01-01
Category : Electronic
ISBN : 0608071862

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Genes, Brain, and Behavior by Paul R. McHugh,Victor A. McKusick Pdf

Author : Anthony Walsh,Jonathan D. Bolen
Publisher : Ashgate Publishing, Ltd.
Page : 240 pages
File Size : 48,6 Mb
Release : 2012
Category : Law
ISBN : 1409438414

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The Neurobiology of Criminal Behavior by Anthony Walsh,Jonathan D. Bolen Pdf

Explores the neurobiology of crime from a biosocial perspective. While the brain and its various mechanisms are the main focus of this work, the authors look at criminal behaviour guided by Nikolas Tinbergen's famous Four Questions: Causation, Development, Phylogeny, and Function.

Author : Orly Lazarov,Giuseppina Tesco
Publisher : Academic Press
Page : 448 pages
File Size : 43,9 Mb
Release : 2016-02-25
Category : Medical
ISBN : 9780128028858

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Genes, Environment and Alzheimer's Disease by Orly Lazarov,Giuseppina Tesco Pdf

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. Provides the first volume to link genetic and environmental risk factors for Alzheimer’s disease and dementia Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer’s disease and cognitive decline Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists

Author : Donald W. Pfaff,Wade H. Berrettini,Tong H. Joh,Stephen C. Maxson
Publisher : CRC Press
Page : 510 pages
File Size : 53,5 Mb
Release : 1999-07-27
Category : Science
ISBN : 1420048228

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Genetic Influences on Neural and Behavioral Functions by Donald W. Pfaff,Wade H. Berrettini,Tong H. Joh,Stephen C. Maxson Pdf

Utilizing the flood of information derived from the Human Genome Project and corresponding efforts to elucidate the mouse genome, Genetic Influences on Neural and Behavioral Functions provides a scholarly catalog, organized logically, of relations between the expression of specific genes, nerve cell biology and behavior, normal and abnormal, in animals AND humans. Sample topics include genes in relation to schiziphrenia, panic disorder, epilepsy, alcoholism, sleep, eating disorders, and more.

Author : William R. Clark,Michael Grunstein
Publisher : Oxford University Press
Page : 128 pages
File Size : 41,6 Mb
Release : 2004-10-14
Category : Science
ISBN : 0195346408

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Are We Hardwired? by William R. Clark,Michael Grunstein Pdf

Books such as Richard Dawkins's The Selfish Gene have aroused fierce controversy by arguing for the powerful influence of genes on human behavior. But are we entirely at the mercy of our chromosomes? In Are We Hardwired?, scientists William R. Clark and Michael Grunstein say the answer is both yes--and no. The power and fascination of Are We Hardwired? lie in their explanation of that deceptively simple answer. Using eye-opening examples of genetically identical twins who, though raised in different families, have had remarkably parallel lives, the authors show that indeed roughly half of human behavior can be accounted for by DNA. But the picture is quite complicated. Clark and Grunstein take us on a tour of modern genetics and behavioral science, revealing that few elements of behavior depend upon a single gene; complexes of genes, often across chromosomes, drive most of our heredity-based actions. To illustrate this point, they examine the genetic basis, and quirks, of individual behavioral traits--including aggression, sexuality, mental function, eating disorders, alcoholism, and drug abuse. They show that genes and environment are not opposing forces; heredity shapes how we interpret our surroundings, which in turn changes the very structure of our brain. Clearly we are not simply puppets of either influence. Perhaps most interesting, the book suggests that the source of our ability to choose, to act unexpectedly, may lie in the chaos principle: the most minute differences during activation of a single neuron may lead to utterly unpredictable actions. This masterful account of the nature-nurture controversy--at once provocative and informative--answers some of our oldest questions in unexpected new ways

Author : Tamas L. Horvath,Joy Hirsch,Zoltán Molnár
Publisher : Academic Press
Page : 445 pages
File Size : 41,8 Mb
Release : 2022-01-08
Category : Medical
ISBN : 9780128180945

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Body, Brain, Behavior by Tamas L. Horvath,Joy Hirsch,Zoltán Molnár Pdf

Body, Brain, Behavior: Three Views and a Conversation describes brain research on the frontiers, with a particular emphasis on the relationship between the brain and its development and evolution, peripheral organs, and other brains in communication. The book expands current views of neuroscience by illustrating the integration of these disciplines. By using a novel method of conversations between 3 scientists of different disciplines, cellular, endocrine, developmental, and social processes are seamlessly woven into topics that relate to contemporary living in health and disease. This book is a critical read for anyone who wants to become familiar with the inner workings of the nervous system and its intimate connections to the universe of contemporary life issues. Introduces the reader to basic principles of brain research and integrative physiology Dissects the dispute between Cajal and Golgi regarding the state-of-the art in the neurosciences and immunobiology Provides a short history of brain research and metabolism Discusses contemporary approaches in the neurosciences, along with the importance of technological versus conceptual advances Examines the dynamics of social connections between two brains, integrating mechanisms of Body/Brain/Behavior-to-Body/Brain/Behavior between subjects

Author : Arturas Petronis,Jonathan Mill
Publisher : Springer Science & Business Media
Page : 320 pages
File Size : 53,8 Mb
Release : 2011-05-19
Category : Medical
ISBN : 9783642174261

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Brain, Behavior and Epigenetics by Arturas Petronis,Jonathan Mill Pdf

Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease? If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment? Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.