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The Genetics of Alcoholism by Henri Begleiter,Benjamin Kissin Pdf
This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.
International Society for Biomedical Research on Alcoholism. Congress
Author : International Society for Biomedical Research on Alcoholism. Congress Publisher : Unknown Page : 268 pages File Size : 52,7 Mb Release : 1989 Category : Alcoholism ISBN : CHI:57877126
Psychological Theories of Drinking and Alcoholism by Kenneth E. Leonard,Howard T. Blane Pdf
Updating and expanding the classic Psychological Theories of Drinking and Alcoholism, this fully revised second edition incorporates state-of-the-art presentations from leaders in the alcoholism field. Contributors review established and emerging approaches that guide research into the psychological processes influencing drinking and alcoholism. The volume's multidisciplinary approach also takes into account biological, pharmacological, and social factors, offering important insights into the development and escalation of drinking problems and the various approaches to treatment. Including significantly expanded coverage of developmental, social learning, and cognitive theories, the book features new chapters on genetics, neurobiology, and emotions.
Alcohol, Drugs, Genes and the Clinical Laboratory by Amitava Dasgupta Pdf
Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures Provides examples from clinical and everyday situations Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse
Types of Alcoholics by Thomas F. Babor,Thomas Babor Pdf
This volume, containing 16 papers, explores recent research and current theory pertaining to alcoholic typologies, giving special emphasis to genetic suscepibility and biological markers of clinical subtypes. This treatment is timely in view of recent trends in genetic epidemiology, treatment matching, and biological markers for alcoholism. The papers present recent research findings, explore commonalities across diverse theoretical and methodological approaches, and consider implications for diagnosis and treatment.
Alcohol Metabolism, Alcohol Intolerance, and Alcoholism by Dharam P. Agarwal,H. Werner Goedde Pdf
Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society. The purpose of this comprehensive monograph is to review the available knowledge concerning the pharmacogenetic basis of alcohol sensitivity and its physiolgical implications and to synthesize the bulk of existing knowledge regarding metabolic features and biomedical disturbances related to alcoholism. The chapters cover a broad array of disciplines including an overview of historical and epidemiological aspects, biochemistry and molecular genetics of enzymes involved in alcohol metabolism, biochemical and neuropsychopharmacological effects of alcohol. Major emphasis is placed on the role of genetic factors in alcoholism. The experimental details are summarized and a comprehensive bibliography is included.
The Natural History of Alcoholism Revisited by George E. Vaillant Pdf
When The Natural History of Alcoholism was first published in 1983, it was acclaimed in the press as the single most important contribution to the literature on alcoholism since the first edition of Alcoholic Anonymous’s Big Book. George Vaillant took on the crucial questions of whether alcoholism is a symptom or a disease, whether it is progressive, whether alcoholics differ from others before the onset of their alcoholism, and whether alcoholics can safely drink. Based on an evaluation of more than 600 individuals followed for over forty years, Vaillant’s monumental study offered new and authoritative answers to all of these questions. In this updated version of his classic book, Vaillant returns to the same subjects with the perspective gained from fifteen years of further follow-up. Alcoholics who had been studied to age 50 in the earlier book have now reached age 65 and beyond, and Vaillant reassesses what we know about alcoholism in light of both their experiences and the many new studies of the disease by other researchers. The result is a sharper focus on the nature and course of this devastating disorder as well as a sounder foundation for the assessment of various treatments.
Author : David J. Kupfer,Michael B. First,Darrel A. Regier Publisher : American Psychiatric Pub Page : 336 pages File Size : 53,8 Mb Release : 2008-08-13 Category : Medical ISBN : 9781585627721
A Research Agenda For DSM V by David J. Kupfer,Michael B. First,Darrel A. Regier Pdf
In the ongoing quest to improve our psychiatric diagnostic system, we are now searching for new approaches to understanding the etiological and pathophysiological mechanisms that can improve the validity of our diagnoses and the consequent power of our preventive and treatment interventions -- venturing beyond the current DSM paradigm and DSM-IV framework. This thought-provoking volume -- produced as a partnership between the American Psychiatric Association, the National Institute of Mental Health, the National Institute on Alcohol Abuse and Alcoholism, and the National Institute on Drug Abuse -- represents a far-reaching attempt to stimulate research and discussion in the field in preparation for the eventual start of the DSM-V process, still several years hence. The book Explores a variety of basic nomenclature issues, including the desirability of rating the quality and quantity of information available to support the different disorders in the DSM in order to indicate the disparity of empirical support across the diagnostic system. Offers a neuroscience research agenda to guide development of a pathophysiologically based classification for DSM-V, which reviews genetic, brain imaging, postmortem, and animal model research and includes strategic insights for a new research agenda. Presents highlights of recent progress in developmental neuroscience, genetics, psychology, psychopathology, and epidemiology, using a bioecological perspective to focus on the first two decades of life, when rapid changes in behavior, emotion and cognition occur. Discusses how to address two important gaps in the current DSM-IV: (1) the categorical method of diagnosing personality disorders and their relationship with Axis I disorders, and (2) the limited provision for the diagnosis of relational disorders -- suggesting a research agenda for personality disorders that considers replacing the current categorical approach with a dimensional classification of personality. Reevaluates the relationship between mental disorders and disability, asserting that research into disability and impairment would benefit from the diagnosis of mental disorders be uncoupled from a requirement for impairment or disability to foster a more vigorous research agenda on the etiologies, courses, and treatment of mental disorders as well as disabilities and to avert unintended consequences of delayed diagnosis and treatment. Examines the importance of culture in psychopathology and the main cultural variables at play in the diagnostic process, stating that training present and future professionals in the need to include cultural factors in the diagnostic process is a logical step in any attempt to develop comprehensive research programs in psychology, psychiatry, and related disciplines. This fascinating work, with contributions from an international group of research investigators, reaches into the core of psychiatry, providing invaluable background and insights for all psychology and psychiatry professionals -- food for thought and further research that will be relevant for years to come.
Drugs and Human Behavior by Denise De Micheli,André Luiz Monezi Andrade,Richard Alecsander Reichert,Eroy Aparecida da Silva,Bruno de Oliveira Pinheiro,Fernanda Machado Lopes Pdf
This book presents the main concepts and tools for the adoption of a biopsychosocial approach to psychotropic substances use and abuse management, prevention and treatment. It aims to provide resources for the design and implementation of health strategies and public policies to deal with psychotropic substances use in a way that fully recognizes the complex articulations between its biological, psychological and social aspects, taking these three dimensions into account to develop both health and social care policies and strategies aimed at psychotropic substance users. The book is organized in five parts. Part one presents a historical overview of psychotropic substances use throughout human history and introduces key concepts to understand the phenomenon from a biopsychosocial perspective. The next three parts approach psychotropic substances use from one of the interrelated dimensions of the biopsychosocial perspective: part two focuses on the neurobiological aspects; part three, on the psychological aspects; and part four, on the social aspects and its implications for public policy design. Finally, a fifth part is dedicated to special topics related to psychotropic substances use. Drugs and Human Behavior: Biopsychosocial Aspects of Psychotropic Substances Use is a guide to public agents, health professionals and social workers interested in adopting the biopsychosocial perspective to develop and implement both health and social care strategies and policies based on an interdisciplinary approach and aimed at dealing with psychotropic substance users in a more humanized way.
Recent Developments in Alcoholism by Marc Galanter Pdf
From the President of the Research Society on Alcoholism Alcohol research has entered an era of growth which brings enhanced opti mism regarding the elucidation of the biochemical and psychosocial factors which combine to produce the phenomena of alcohol abuse and alcoholism. The solidification of knowledge regarding the genetic determinants of certain alcohol-related problems puts on firm footing the biological approaches for developing solutions to these problems. The current volume of Recent Devel opments in Alcoholism contains an excellent blend of information both on stud ies assessing the behavioral and physiological variables which may be ge netically linked to an individual's risk of developing problems with alcohol, and on clinical and basic science investigations of the pathological conse quences of excessive ethanol ingestion. Further progress in the alcoholism research area will continue to require investigation of the interactions of en vironmental variables with the genetically determined biology of an individ ual. Novel techniques in the fields of molecular genetics, physical chemistry, and behavioral pharmacology are being brought to bear on the central issues in the field, and the addition of these tools to the science of alcohol research brings closer the prospect of fruitful clinical application of our basic knowl edge. The Research Society on Alcoholism remains devoted to the task of promoting the generation of knowledge regarding the actions of alcohol and the mechanisms which produce alcohol abuse and alcoholism.
