Genetics And Genomics For The Cardiologist

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Genetics and Genomics for the Cardiologist

Gian Antonio Danieli
Genetics and Genomics for the Cardiologist Book PDF

Author : Gian Antonio Danieli
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461510253

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Genetics and Genomics for the Cardiologist by Gian Antonio Danieli Pdf

Genetics and Genomics for the Cardiologist is a concise, but comprehensive volume for the clinical cardiologist or medical student interested in learning how molecular genetics is now being applied to prevention and treatment of heart diseases, from DNA tests to pharmacogenomics and gene-based therapeutics. The volume, written in a plain language, contains detailed figures. A rich glossary, three appendices, many references and several URLs provide additional sources of information.

Cardiovascular Genetics and Genomics for the Cardiologist

Victor J. Dzau, MD,Choong-Chin Liew, PhD
Cardiovascular Genetics and Genomics for the Cardiologist Book PDF

Author : Victor J. Dzau, MD,Choong-Chin Liew, PhD
Publisher : John Wiley & Sons
Page : 328 pages
File Size : 53,7 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9780470765944

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Cardiovascular Genetics and Genomics for the Cardiologist by Victor J. Dzau, MD,Choong-Chin Liew, PhD Pdf

Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way cardiovascular medicine is practiced • what material has immediate relevance to the practicing clinician • how to incorporate genetics and genomics in your practice to ensure up-to-date patient care The book opens with introductory chapters, then discusses: • cardiovascular single gene disorders • cardiovascular polygenic disorders • therapies and applications Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.

Cardiovascular Genetics and Genomics

Dhavendra Kumar,Perry Elliott
Cardiovascular Genetics and Genomics Book PDF

Author : Dhavendra Kumar,Perry Elliott
Publisher : Springer
Page : 920 pages
File Size : 48,9 Mb
Release : 2018-01-17
Category : Medical
ISBN : 9783319661148

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Cardiovascular Genetics and Genomics by Dhavendra Kumar,Perry Elliott Pdf

This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practice includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.

Cardiovascular Genetics and Genomics in Clinical Practice

Sanjiv J. Shah, MD,Donna K. Arnett, PhD
Cardiovascular Genetics and Genomics in Clinical Practice Book PDF

Author : Sanjiv J. Shah, MD,Donna K. Arnett, PhD
Publisher : Springer Publishing Company
Page : 326 pages
File Size : 43,7 Mb
Release : 2014-11-10
Category : Medical
ISBN : 9781620700143

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Cardiovascular Genetics and Genomics in Clinical Practice by Sanjiv J. Shah, MD,Donna K. Arnett, PhD Pdf

This book will provide a unique approach to cardiovascular genetics and genomics through utilizing clinical cases to illustrate the basic science concepts as the practitioner will encounter them in regular clinical practice. Through the teaching value of real-world case discussions, the principles of cardiovascular genetics and genomics can be illustrated clearly and memorably, and the clinician will be able to relate the cases shown in the book with those seen in direct experience. The book opens with a "primer" of the basic scientific concepts, providing the reader with a clear, easy to understand "toolkit" for the discussions of the genetic science in clinical practice.

Cardiovascular Genomics

Mohan K. Raizada,Julian F. R. Paton,Michael J. Katovich,Sergey Kasparov
Cardiovascular Genomics Book PDF

Author : Mohan K. Raizada,Julian F. R. Paton,Michael J. Katovich,Sergey Kasparov
Publisher : Springer Science & Business Media
Page : 367 pages
File Size : 44,9 Mb
Release : 2008-02-24
Category : Medical
ISBN : 9781592598830

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Cardiovascular Genomics by Mohan K. Raizada,Julian F. R. Paton,Michael J. Katovich,Sergey Kasparov Pdf

Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

Post-Genomic Cardiology

José Marín-García
Post Genomic Cardiology Book PDF

Author : José Marín-García
Publisher : Academic Press
Page : 935 pages
File Size : 52,6 Mb
Release : 2014-05-09
Category : Medical
ISBN : 9780124046429

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Post-Genomic Cardiology by José Marín-García Pdf

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Cardiovascular Genetics and Genomics

Dan M. Roden
Cardiovascular Genetics and Genomics Book PDF

Author : Dan M. Roden
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 44,8 Mb
Release : 2009-04-01
Category : Medical
ISBN : 1444311778

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Cardiovascular Genetics and Genomics by Dan M. Roden Pdf

This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.

Genetic Causes of Cardiac Disease

Jeanette Erdmann,Alessandra Moretti
Genetic Causes of Cardiac Disease Book PDF

Author : Jeanette Erdmann,Alessandra Moretti
Publisher : Springer Nature
Page : 407 pages
File Size : 40,9 Mb
Release : 2019-11-27
Category : Medical
ISBN : 9783030273712

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Genetic Causes of Cardiac Disease by Jeanette Erdmann,Alessandra Moretti Pdf

This book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists.

Principles and Practice of Clinical Cardiovascular Genetics

Dhavendra Kumar,Perry Elliott
Principles and Practice of Clinical Cardiovascular Genetics Book PDF

Author : Dhavendra Kumar,Perry Elliott
Publisher : Oxford University Press, USA
Page : 623 pages
File Size : 55,6 Mb
Release : 2010
Category : Language Arts & Disciplines
ISBN : 9780195368956

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Principles and Practice of Clinical Cardiovascular Genetics by Dhavendra Kumar,Perry Elliott Pdf

Consisting of contributions from experts in all specialties of cardiovascular genetics and applied clinical cardiology, Principles and Practice of Clinical Cardiovascular Genetics serves as the comprehensive volume for any clinician or resident in cardiology and genetics. Each chapter provides a detailed and comprehensive account on the molecular genetics and clinical practice related to specific disorders or groups of disorders, including Marfan syndrome, thoracic and abdominal aortic aneurysms, hypertrophic, dilated and restrictive cardiomyopathies and Arrhythmogenic right ventricular cardiomyopathy, as well as many others. All sections comprehensively address cardiovasuclar genetic disorders, beginning with an introduction and including separate sections on the disease's basic biological aspects, specific genetic mechanisms or issues, clinical aspects, genetic management (e.g., genetic diagnosis, risk assessment, genetic counseling, genetic testing), and clinical management issues. The final section exclusively addresses the management of cardiovascular genetic disorders, specifically considering stem cell therapy, genetic counseling, pharmacogenomics and the social and ethical issues surrounding disease treatment.

Clinical Cardiogenetics

H.F. Baars,P.A.F.M. Doevendans,J.J. van der Smagt
Clinical Cardiogenetics Book PDF

Author : H.F. Baars,P.A.F.M. Doevendans,J.J. van der Smagt
Publisher : Springer Science & Business Media
Page : 453 pages
File Size : 52,6 Mb
Release : 2010-12-25
Category : Medical
ISBN : 9781849964715

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Clinical Cardiogenetics by H.F. Baars,P.A.F.M. Doevendans,J.J. van der Smagt Pdf

Clinical management and signs are the focus of this practical cardiogenetic reference for those who are involved in the care for cardiac patients with a genetic disease. With detailed discussion of the basic science of cardiogenetics in order to assist in the clinical understanding of the topic. The genetic causes of various cardiovascular diseases are explained in a concise clinical way that reinforces the current management doctrine in a practical manner. The authors will cover the principles of molecular genetics in general but also specific to cardiac diseases. They will discuss the etiology, pathogenesis, pathophysiology, clinical presentation, clinical diagnosis, molecular diagnosis and treatment of each cardiogenetic disease separately. Therapy advice, ICD indications, indications for and manner of further family investigation will all be covered, while each chapter will also contain take-home messages to reinforce the key points. The chapters reviewing the different diseases will each contain a table describing the genes involved in each. Each chapter will also contain specific illustrations, cumulatively giving a complete, practical review of each cardiogenetic disease separately. Special emphasis will be given to advice on how to diagnose and manage cardiogenetic diseases in clinical practice, which genes should be investigated and why, and the pros and cons of genetic testing. Guidelines for investigation in families with sudden cardiac death at young age will also be included. This book will be written for the general cardiologist and the clinical geneticist who is involved in cardiac patients and will provide answers to question such as: Which genes are involved and which mutations? What is the effect of the mutation at cellular level? Which genes should be tested and why? What is the value of a molecular diagnosis? Does it influence therapy? When should the first degree relatives be tested and in which way?

Molecular Genetics & Gene Therapy of Cardiovascular Diseases

S. C. Mockrin
Molecular Genetics Gene Therapy of Cardiovascular Diseases Book PDF

Author : S. C. Mockrin
Publisher : CRC Press
Page : 616 pages
File Size : 42,7 Mb
Release : 1996-01-02
Category : Medical
ISBN : 9781482273243

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Molecular Genetics & Gene Therapy of Cardiovascular Diseases by S. C. Mockrin Pdf

Provides detailed discussions of the most recent developments in gene mapping and manipulation to improve the diagnosis, detection, prevention, and treatment of various cardiovascular diseases--including hypertension, arrhythmias, inherited cariomyopathies, hyperlipidemia, aortic aneurysms, Marfan syndrome, and myocardial infarction. Written by nea

Inherited Cardiac Disease

Perry Elliott,Pier D. Lambiase,Dhavendra Kumar
Inherited Cardiac Disease Book PDF

Author : Perry Elliott,Pier D. Lambiase,Dhavendra Kumar
Publisher : Oxford University Press
Page : 433 pages
File Size : 50,5 Mb
Release : 2020-11-11
Category : Medical
ISBN : 9780192564405

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Inherited Cardiac Disease by Perry Elliott,Pier D. Lambiase,Dhavendra Kumar Pdf

Every year, thousands of people die or suffer chronic disability as the result of inherited diseases of the cardiovascular system. In many cases, diagnosis of inherited disease is delayed or missed owing to a lack of awareness, and an even greater number of relatives are exposed to unnecessary risk. This new edition of Inherited Cardiac Disease provides a comprehensive summary of the aetiology, presentation, and management of genetic disorders of the cardiovascular system. Fully updated to reflect the advances in molecular genetic technologies and the publication of national guidelines for the management of families with inherited cardiac diseases, it retains the first edition's broad scope and applicability to all members of the multidisciplinary team, from specialists in cardiology and clinical genetics, to genetic counsellors, paediatricians, nurse specialists, and GPs who may come into contact with families presenting with inherited cardiac diseases. Containing both a short section on the general principles of cardiovascular genetics, individual disorders are then examined in detail, each featuring a clinical summary, diagnostic tests and special investigations, and treatments relevant to each inherited cardiac disease. Written in the succinct bullet-point style of the Oxford Specialist Handbooks, this new edition of Inherited Cardiac Disease delivers key information in an accessible manner, and is an invaluable guide to anyone who works with patients who are affected by inherited diseases of the cardiovascular system in their practice.

Heart Genomics

Hong Jiang,Ming Liu
Heart Genomics Book PDF

Author : Hong Jiang,Ming Liu
Publisher : Springer
Page : 374 pages
File Size : 41,7 Mb
Release : 2018-10-11
Category : Medical
ISBN : 9789811314292

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Heart Genomics by Hong Jiang,Ming Liu Pdf

This book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.

Genomic and Molecular Cardiovascular Medicine

Dhavendra Kumar,Arthur A.M. Wilde,Perry Mark Elliott
Genomic and Molecular Cardiovascular Medicine Book PDF

Author : Dhavendra Kumar,Arthur A.M. Wilde,Perry Mark Elliott
Publisher : Elsevier
Page : 462 pages
File Size : 40,9 Mb
Release : 2024-06-24
Category : Science
ISBN : 9780128229200

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Genomic and Molecular Cardiovascular Medicine by Dhavendra Kumar,Arthur A.M. Wilde,Perry Mark Elliott Pdf

The Genomic and Molecular Cardiovascular Medicine largely focuses on pertinent genomic and molecular aspects of cardiovascular medicine relevant to all levels of clinical practice, from primary care to preventive healthcare. The book also focuses on practice applications of translational genomic and molecular developments and advances that impact on cardiovascular system structure and function. Each chapter is evidence-based and comprehensive, with in-depth, cutting-edge knowledge relevant to the practice of clinical cardiology and cardiovascular surgery. The book aims to fill a major gap of knowledge resource focused on genomic and molecular aspects of contemporary cardiovascular medicine and surgery practice. In view of scientific and technical complexities of the field, the book is written by a team of globally acknowledged experts in respective clinical, investigative, therapeutic and preventive aspects. The current practices within cardiovascular medicine and surgery offer excellent opportunity for genomic and molecular applications to achieve the high order effectiveness with maximum efficiency. Includes clinical applications of genomic and molecular new knowledge, along with advances in the practice of cardiovascular medicine and surgery Provides wide coverage of all major clinical and preventive aspects of clinical cardiology, including multi-disciplinary team care Focuses on targeted gene and molecular therapy in clinical cardiovascular medicine and surgery

Molecular Cardiology for the Cardiologists

Bernard Swynghedauw
Molecular Cardiology for the Cardiologists Book PDF

Author : Bernard Swynghedauw
Publisher : Springer Science & Business Media
Page : 266 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461520191

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Molecular Cardiology for the Cardiologists by Bernard Swynghedauw Pdf

Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. With this in mind, special efforts have been made to present many comprehensive schemes and drawings, as well as teaching tables. The five parts of the book provide a general introduction to the new language of biology; the normal structure of the heart and blood vessels; the physiopathology and the new therapeutic avenues that have been opened up by the new biology. A concise summary of the keys that assist the cardiologist or student who seeks to learn and read more about this field. Provides practical examples to illustrate the clinical interest of the new approach.