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Author : Miguel Angel Brieño-Enriquez,Francesca Elizabeth Duncan,Arjumand Ghazi,Michael Klutstein,Vittorio Sebastiano,Jessica Tyler
Publisher : Frontiers Media SA
Page : 287 pages
File Size : 40,9 Mb
Release : 2022-07-14
Category : Science
ISBN : 9782889765676
Author : Barry R. Zirkin
Publisher : Springer Science & Business Media
Page : 303 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461222064
An exploration of germ cell development, division, disruption and death, designed for reproductive endocrinologists, microbiologists and physiologists. Topics covered include: cloning and characterization of genes expressed in germ cell lines; spermatological transplantation; and testicular ageing.
Author : Richard Ivell,Adolf-Friedrich Holstein
Publisher : Springer Science & Business Media
Page : 335 pages
File Size : 46,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461559139
THE FASCINATION The male germ cell is the only cell of the human organism that leaves the body when it has achieved its final, highly sophisticated structure and properties. The male germ cell is designed for one purpose only: to reach the female gametes and to fertilize them. The various stages in the development of the male germ cell are characterized by proliferative phases, by the recombination of the maternal and paternal chromosomes, and by the differentiation and development of a specialized transport vehicle, the spermato zoon. Furthermore, the establishment of a special pool of stem cells, the spermatogonia, guarantees the continuity of the sperm-generation process from puberty to old age. THE FATE OF THE MALE GERM CELL The destiny of any individual germ cell is determined by a program that we know only in fragments. On the one hand every human male is able to produce many billions of germ cells in his lifetime, yet the chance of any single sperm reaching and fertilizing the female germ cell is exceedingly rare. A fertility disturbance means that somewhere during the complicated playing out of the germ cell program mistakes are made, and the program fails. It is still a fact that more than 50% of men presenting with male factor infertility have to be diagnosed as idiopathic, largely because of our lack of knowledge and conse quent lack of appropriate diagnostic tools.
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 53,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : Heide Schatten
Publisher : Humana Press
Page : 418 pages
File Size : 47,9 Mb
Release : 2004-03-24
Category : Science
ISBN : 1588292576
The study of germ cells has undergone enormous advances in recent years and has entered into an explosive phase of new discoveries with the introd- tion of transgenic technologies and nuclear cloning. Basic knowledge and te- niques developed for lower vertebrate and invertebrate systems have facilitated the study of higher vertebrates, including humans. Many experiments that have first been performed on lower vertebrates provided the tools and strategies that could later be applied to other less readily available mammalian systems. The discovery of centrosomes in ascidians and sea urchin eggs now benefits st- ies of fertility and infertility in mammals including humans. External in vitro fertilization, now a common technique in assisted fertilization has only been possible as a result of numerous studies in lower systems in which external fertilization is natural. Egg activation, first explored in sea urchin and asc- ian eggs, now benefits cloning efficiency in farm and domestic animals. Gene manipulations and molecular methods have added to the possibilities of p- ducing live offspring with enormous biomedical, ecological, and economic implications. All sexually reproducing organisms produce primordial germ cells, a small population of cells that differentiate into gametes of either sex that carry to- potency, an ability to develop into an entire new organism. The two volumes on germ cells combine techniques in a variety of different systems and have selected those systems that have provided landmarks in advancing our kno- edge on germ cells.
Author : Heide Schatten
Publisher : Humana
Page : 0 pages
File Size : 46,7 Mb
Release : 2010-12-01
Category : Science
ISBN : 1617373745
All sexually reproducing organisms produce primordial germ cells, a small population of cells that differentiate into gametes of either sex and carry to- potency, an ability to develop into an entire new organism. The study of germ cells has undergone enormous advances in recent years and has entered into an explosive phase of new discoveries with the introduction of transgenic te- nologies and nuclear cloning. Basic knowledge and techniques developed for lower vertebrate and invertebrate systems have facilitated the study of higher vertebrates, including humans. Many experiments that have first been performed on lower vertebrates provided the tools and strategies that could later be applied to other less readily available mammalian systems. The discovery of centrosomes in ascidians and sea urchin eggs now benefits studies of fertility and infertility in mammals. External in vitro fertilization, now a common technique in assisted fertilization, has only been possible as a result of numerous studies in lower systems in which external fertilization is natural. Egg activation, first explored in sea urchin and ascidian eggs, now benefits techniques designed to increase cl- ing efficiency in farm and domestic animals. Gene manipulations and molecular methods have added to the possibilities of producing live offspring with en- mous biomedical, ecological, and economic implications. The two volumes on germ cells combine techniques in a variety of d- ferent systems; we have selected those systems that have provided landmarks in advancing our knowledge on germ cells.
Author : Heide Schatten
Publisher : Humana Press
Page : 316 pages
File Size : 53,5 Mb
Release : 2004-03-15
Category : Science
ISBN : 1588291219
All sexually reproducing organisms produce primordial germ cells, a small population of cells that differentiate into gametes of either sex and carry to- potency, an ability to develop into an entire new organism. The study of germ cells has undergone enormous advances in recent years and has entered into an explosive phase of new discoveries with the introduction of transgenic te- nologies and nuclear cloning. Basic knowledge and techniques developed for lower vertebrate and invertebrate systems have facilitated the study of higher vertebrates, including humans. Many experiments that have first been performed on lower vertebrates provided the tools and strategies that could later be applied to other less readily available mammalian systems. The discovery of centrosomes in ascidians and sea urchin eggs now benefits studies of fertility and infertility in mammals. External in vitro fertilization, now a common technique in assisted fertilization, has only been possible as a result of numerous studies in lower systems in which external fertilization is natural. Egg activation, first explored in sea urchin and ascidian eggs, now benefits techniques designed to increase cl- ing efficiency in farm and domestic animals. Gene manipulations and molecular methods have added to the possibilities of producing live offspring with en- mous biomedical, ecological, and economic implications. The two volumes on germ cells combine techniques in a variety of d- ferent systems; we have selected those systems that have provided landmarks in advancing our knowledge on germ cells.
Author : András Balázs
Publisher : Ardent Media
Page : 336 pages
File Size : 53,5 Mb
Release : 1974
Category : Science
ISBN : 0842271597
Author : P.H. Vogt
Publisher : Karger Medical and Scientific Publishers
Page : 178 pages
File Size : 44,8 Mb
Release : 2017-09-12
Category : Medical
ISBN : 9783318060980
Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.
Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee
Publisher : National Academies Press
Page : 476 pages
File Size : 48,7 Mb
Release : 1986-02-01
Category : Nature
ISBN : 9780309036870
The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.
Author : Lewis Wolpert
Publisher : Oxford University Press
Page : 153 pages
File Size : 48,6 Mb
Release : 2011-08-25
Category : Science
ISBN : 9780199601196
"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.
Author : Arlene Chiu,Mahendra S. Rao
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 47,8 Mb
Release : 2003-08-01
Category : Science
ISBN : 9781592594238
A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.
Author : Albert Altchek,Liane Deligdisch,Nathan Kase
Publisher : Elsevier
Page : 568 pages
File Size : 45,6 Mb
Release : 2003-09-04
Category : Medical
ISBN : 9780080494517
This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine
Author : Richard M. Hopper
Publisher : John Wiley & Sons
Page : 2735 pages
File Size : 45,7 Mb
Release : 2014-08-18
Category : Medical
ISBN : 9781118470855
Bovine Reproduction is a comprehensive, current reference providing information on all aspects of reproduction in the bull and cow. Offering fundamental knowledge on evaluating and restoring fertility in the bovine patient, the book also places information in the context of herd health where appropriate for a truly global view of bovine theriogenology. Printed in full color throughout, the book includes 83 chapters and more than 550 images, making it the most exhaustive reference available on this topic. Each section covers anatomy and physiology, breeding management, and reproductive surgery, as well as obstetrics and pregnancy wastage in the cow. Bovine Reproduction is a welcome resource for bovine practitioners, theriogenologists, and animal scientists, as well as veterinary students and residents with an interest in the cow.
Author : Eliezer Girsh
Publisher : Cambridge University Press
Page : 257 pages
File Size : 53,9 Mb
Release : 2021-05-06
Category : Medical
ISBN : 9781108744386
A comprehensive guide for trainee embryologists and medical students in the specialized techniques and technology of assisted reproduction.
