Global Perspectives On Precision Medicine

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Global Perspectives on Precision Medicine

Evangel Sarwar
Global Perspectives on Precision Medicine Book PDF

Author : Evangel Sarwar
Publisher : Springer Nature
Page : 239 pages
File Size : 41,6 Mb
Release : 2023-04-04
Category : Philosophy
ISBN : 9783031285936

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Global Perspectives on Precision Medicine by Evangel Sarwar Pdf

This book presents the promises of Precision Medicine (PM) and the challenges of its implementation in daily clinical routine, while addressing the anticipated ethical and social implications. It is the first book that critically analyzes the potential and the dilemmas relevant to genomics and precision medicine from healthcare, public health and global perspectives. The nine chapters presented in this book elaborate on pharmacogenomics' crucial role in maximizing the potential benefits and minimizing medication's potential risks in groups of people, especially in cancer treatment and other health conditions. Infectious and non-communicable diseases (NCDs) are also discussed in this book by identifying challenges and ways to overcome them. Essential concepts are addressed, such as health-related benefits and harm to individuals and the broader community, including threats to individual privacy and autonomy, which warrant just distribution of scarce resources. The book also identifies and addresses the lack of competency in the healthcare workforce in the era of PM and discusses the path to laying the ethical foundation for the implementation of PM in healthcare organizations.

Global Bioethics

Henk ten Have
Global Bioethics Book PDF

Author : Henk ten Have
Publisher : Routledge
Page : 272 pages
File Size : 50,8 Mb
Release : 2016-02-10
Category : Business & Economics
ISBN : 9781317300823

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Global Bioethics by Henk ten Have Pdf

The panorama of bioethical problems is different today. Patients travel to Thailand for fast surgery; commercial surrogate mothers in India deliver babies to parents in rich countries; organs, body parts and tissues are trafficked from East to Western Europe; physicians and nurses migrating from Africa to the U.S; thousands of children or patients with malaria, tuberculosis and AIDS are dying each day because they cannot afford effective drugs that are too expensive. Mainstream bioethics as it has developed during the last 50 years in Western countries is evolving into a broader approach that is relevant for people across the world and is focused on new global problems. This book provides an introduction into the new field of global bioethics. Addressing these problems requires a broader vision of bioethics that not only goes beyond the current emphasis on individual autonomy, but that criticizes the social, economic and political context that is producing the problems at global level. This book argues that global bioethics is a necessity because the social, economic and environmental effects of globalization require critical responses. Global bioethics is not a finished product that can simply be applied to solve global problems, but it is the ongoing result of interaction and exchange between local practices and global discourse. It combines recognition of differences and respect for cultural diversity with convergence towards common perspectives and shared values. The book examines the nature of global problems as well as the type of responses that are needed, in order to exemplify the substance of global bioethics. It discusses the ethical frameworks that are available for global discourse and shows how these are transformed into global governance mechanisms and practices.

Progress and Challenges in Precision Medicine

Mukesh Verma,Debmalya Barh
Progress and Challenges in Precision Medicine Book PDF

Author : Mukesh Verma,Debmalya Barh
Publisher : Academic Press
Page : 344 pages
File Size : 53,5 Mb
Release : 2016-12-22
Category : Medical
ISBN : 9780128095027

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Progress and Challenges in Precision Medicine by Mukesh Verma,Debmalya Barh Pdf

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Personalizing Precision Medicine

Kristin Ciriello Pothier
Personalizing Precision Medicine Book PDF

Author : Kristin Ciriello Pothier
Publisher : John Wiley & Sons
Page : 228 pages
File Size : 51,6 Mb
Release : 2017-08-30
Category : Medical
ISBN : 9781118792124

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Personalizing Precision Medicine by Kristin Ciriello Pothier Pdf

The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. She reviews the full continuum of personalizing precision medicine, including diagnostics, therapeutics, big data, supportive care, regulation, and reimbursement and innovation in precision medicine worldwide. • Combines a unique cross section of history, current technologies, and future directions for how precision medicine has and will affect people worldwide • Reviews precision medicine around the world, including the US, China, Japan, the Middle East, India, Europe, and Latin America • Discusses a number of diseases areas – cancer, cardiovascular, neurodegenerative, infectious disease, pain, immunology, rare diseases • Includes information and quotes from over 100 interviews with key industry experts in biotech, pharma, informatics, diagnostics, health providers, advocacy groups, and more. • Includes stories illustrating current issues and future promises in precision medicine for a human touch

Can precision medicine be personal; Can personalized medicine be precise?

Y. Michael Barilan,Margherita Brusa,Aaron Ciechanover
Can precision medicine be personal Can personalized medicine be precise Book PDF

Author : Y. Michael Barilan,Margherita Brusa,Aaron Ciechanover
Publisher : Oxford University Press
Page : 353 pages
File Size : 46,8 Mb
Release : 2022-02-10
Category : Medical
ISBN : 9780192608680

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Can precision medicine be personal; Can personalized medicine be precise? by Y. Michael Barilan,Margherita Brusa,Aaron Ciechanover Pdf

People have always sought medical care that is tailored to every individual patient. Alongside with the historical development of institutions of care, the vision of personal and 'holistic' care persisted. Patient-centred medicine, interpersonal communication and shared decision making have become central to medical practice and services. This evolving vision of 'personalized medicine' is in the forefront of medicine, creating debates among ethicists, philosophers and sociologists of medicine about the nature of disease and the definition of wellness, the impact on the daily life of patients, as well as its implications on low-income countries. Is increased 'precision' also an improvement on the personal aspects of care or erosion of privacy? Do 'precise' and 'personalized' approach marginalize public health, and can this care be personalized without attention to culture, economy and society? The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science. The contributing scholars come from all over the world and from different cultural backgrounds providing reflective perspectives of history of ideas, critical theory and technology assessment, together with the actual work done by pioneers in the field. It explores issues such as global justice, gender, public health, pharmaceutical industry, international law and religion, and explores themes discussed in relation to personalized medicine such as new-born screening and disorders of consciousness. This book will be of interest to academicians in bioethics, history of medicine, social sciences of medicine as well as general educated readers.

Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems

Romina Prziklas Druzeta,Marinko Škare,Sandra Kraljević Pavelić
Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems Book PDF

Author : Romina Prziklas Druzeta,Marinko Škare,Sandra Kraljević Pavelić
Publisher : Nova Science Publishers
Page : 540 pages
File Size : 48,5 Mb
Release : 2021-12-22
Category : Social Science
ISBN : 168507393X

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Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems by Romina Prziklas Druzeta,Marinko Škare,Sandra Kraljević Pavelić Pdf

"The book Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems represents a valuable interdisciplinary contribution created to fill an existing gap in the field of health economics and healthcare systems. The book brings the latest insights from the growing field of health economics and healthcare systems. It deals with various economic, technological, sociological, ethical, legal and philosophical implications and questions arising from the development and implementation of personalized medicine. It is unprecedented in combining practical guidelines for the use of economic tools and techniques with an analysis of the current process of decision-making in the health service sector. The book also provides several insights into the factors that determine human health, the socioeconomic aspects of population aging and the social implications of the evolving burden of disease. Some contributions are highly innovative and cover extremely relevant branches of medicine such as oncology, neurology and endocrinology. In addition, in a brave, yet professional and sovereign manner, the book covers the issue of biological predictors of health outcomes; though they are currently mainly used as global analytical methods, they are yet to be applied or have only recently been applied in clinical medicine. Further, it provides an example from traditional Korean medicine, a proven and valuable tool for personalized medical healthcare. This edition is unique in the sense that 30 chapters were written by 41 authors, all of them experts in their respective fields of research. The authors hail from Croatia, Hungary, South Korea and the United States. The volume is intended to serve as valuable teaching material for university students, as well as a reference book for research scholars, policymakers, business executives, health managers, physicians and freelance readers"--

Toward Precision Medicine

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease
Toward Precision Medicine Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease
Publisher : National Academies Press
Page : 142 pages
File Size : 40,8 Mb
Release : 2012-01-16
Category : Medical
ISBN : 9780309222228

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Toward Precision Medicine by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease Pdf

Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Personalised Health Care

Stefania Boccia,Róza Ádány,Paolo Villari,Martina C. Cornel,Corrado De Vito,Roberta Pastorino
Personalised Health Care Book PDF

Author : Stefania Boccia,Róza Ádány,Paolo Villari,Martina C. Cornel,Corrado De Vito,Roberta Pastorino
Publisher : Springer Nature
Page : 135 pages
File Size : 53,8 Mb
Release : 2020-11-23
Category : Medical
ISBN : 9783030523992

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Personalised Health Care by Stefania Boccia,Róza Ádány,Paolo Villari,Martina C. Cornel,Corrado De Vito,Roberta Pastorino Pdf

Practitioners are increasingly adopting a personalised medicine approach to individually tailored patient care, especially disease diagnosis and treatment with the use of biomarkers. However, development and implementation of such approaches to chronic disease prevention need further investigation and concerted efforts for proper use in healthcare systems. This book provides high-quality, multidisciplinary knowledge from research in personalised medicine, specifically personalised prevention of chronic disease. It addresses different perspectives of prevention in the field, and is the outcome of a four-year work of the Personalized prevention of Chronic Disease (PRECeDI) Consortium, a multi-disciplinary and multi-professional team of experts. The Consortium jointly agreed to document and address the five aspects or domains of personalised medicine and prevention as individual chapters: Identification of biomarkers for the prevention of chronic disease Evaluation of predictive genomic applications Ethico-legal and policy issues surrounding personalised medicine Roles and responsibilities of stakeholders in informing healthy individuals on their genome: a sociotechnical analysis Identification of organisational models for the provision of predictive genomic applications The book focuses on the Consortium's recommendations that are derived from each of these domains based on up-to-date evidence and research that the authors write, follow, and systematically organise and report. Personalisation of health care is, eventually, a driver of innovation in research and healthcare systems. With this SpringerBrief on Personalised Health Care: Fostering Precision Medicine Advancements for Gaining Population Health Impact, the Consortium provides further evidence of the clinical validity and utility of personalised medicine with special emphasis on the prevention of chronic diseases. The book is a useful resource for policy makers, industry and healthcare professionals, scientists, technology-sector professionals, investors, citizens, and private companies that need proper advice to realise the potential of personalised medicine.

Personalized and Precision Medicine Informatics

Terrence Adam,Constantin Aliferis
Personalized and Precision Medicine Informatics Book PDF

Author : Terrence Adam,Constantin Aliferis
Publisher : Springer Nature
Page : 349 pages
File Size : 41,9 Mb
Release : 2019-09-17
Category : Medical
ISBN : 9783030186265

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Personalized and Precision Medicine Informatics by Terrence Adam,Constantin Aliferis Pdf

This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals.

Personalized Medicine in the Making

Chiara Beneduce,Marta Bertolaso
Personalized Medicine in the Making Book PDF

Author : Chiara Beneduce,Marta Bertolaso
Publisher : Springer Nature
Page : 334 pages
File Size : 48,8 Mb
Release : 2022-03-07
Category : Medical
ISBN : 9783030748043

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Personalized Medicine in the Making by Chiara Beneduce,Marta Bertolaso Pdf

This book offers a multidisciplinary look at the much-debated concept of “personalized medicine”. By combining a humanistic and a scientific approach, the book builds up a multidimensional way to understand the limits and potentialities of a personalized approach in medicine and healthcare. The book reflects on personalized medicine and complex diseases, the relationship between personalized medicine and the new bio-technologies, personalized medicine and personalized nutrition, and on some ethical, political, economic, and social implications of personalized medicine. This volume is of interest to researchers from several disciplines including philosophy, bio-medicine, and the social sciences. Chapter 16, “The Impact of Fantasy” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Pharmacogenomics in Precision Medicine

Weimin Cai,Zhaoqian Liu,Liyan Miao,Xiaoqiang Xiang
Pharmacogenomics in Precision Medicine Book PDF

Author : Weimin Cai,Zhaoqian Liu,Liyan Miao,Xiaoqiang Xiang
Publisher : Springer Nature
Page : 290 pages
File Size : 47,7 Mb
Release : 2020-06-12
Category : Medical
ISBN : 9789811538957

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Pharmacogenomics in Precision Medicine by Weimin Cai,Zhaoqian Liu,Liyan Miao,Xiaoqiang Xiang Pdf

This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.

AI and IoT-Based Technologies for Precision Medicine

Khang, Alex
AI and IoT Based Technologies for Precision Medicine Book PDF

Author : Khang, Alex
Publisher : IGI Global
Page : 585 pages
File Size : 47,9 Mb
Release : 2023-10-18
Category : Medical
ISBN : 9798369308776

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AI and IoT-Based Technologies for Precision Medicine by Khang, Alex Pdf

In the post-COVID-19 healthcare landscape, the demand for smart healthcare solutions and precision medicine systems has grown significantly. To address these challenges, the book AI and IoT-Based Technologies for Precision Medicine provides a comprehensive resource for doctors, researchers, engineers, and students. By leveraging AI and IoT technologies, the book equips healthcare professionals with advanced tools and methodologies for predictive disease analysis, informed decision-making, and other aspects of precision medicine. This resource bridges the gap between theory and practice, exploring concepts like machine learning, deep learning, computer vision, AI-integrated applications, IoT-based technologies, healthcare data analytics, and biotechnology applications. Through this, the book empowers healthcare practitioners to pioneer innovative solutions that enhance efficiency, accuracy, and security in medical practices. AI and IoT-Based Technologies for Precision Medicine not only offer insights into the potential of AI-powered applications and IoT-equipped techniques in smart healthcare but also foster collaboration among healthcare scholars and professionals. This authoritative guide encourages knowledge sharing and collaboration to harness the transformative potential of AI and IoT, leading to revolutionary advancements in medical practices and healthcare services. With this book as a guide, readers can navigate the evolving landscape of high-tech medicine, taking confident steps toward a cutting-edge and precise medical ecosystem.

Global Perspectives on Stem Cell Technologies

Aditya Bharadwaj
Global Perspectives on Stem Cell Technologies Book PDF

Author : Aditya Bharadwaj
Publisher : Springer
Page : 243 pages
File Size : 41,6 Mb
Release : 2017-10-30
Category : Social Science
ISBN : 9783319637877

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Global Perspectives on Stem Cell Technologies by Aditya Bharadwaj Pdf

This book takes as its point of departure a humble cell lying on the intersection of ideas as diverse and yet interlaced as life, knowledge, commerce, governance, and ethics. It seeks to deepen the understanding of stem cell entities and the concerns, hopes, and aspirations that shape and make them viable therapeutic entities in the context of rapid globalization. Several key intersections between individual, group, and institutional relationships have become central to locating and debating the production of stem cells today. This edited collection addresses three overarching concerns: regenerating the notion of ethics, the emerging therapeutic horizons, and the position of the patient. As a whole this book seeks to explain how stem cells are accommodated, contested, and used in contemporary India and around the globe through an informed unpacking of issues underpinning contestation and promotion bestriding these technological developments. The authors offer a truly multi-disciplinary perspective, stimulating conversation between the social sciences, biological sciences and the patient. The concerns expressed and highlighted by these conversations are embedded in a vast geo-political expanse stretching from India to Euro-America and will be of great interest to academics and practitioners across fields including science technology studies, medicine and international development.

Precision Medicine in Clinical Practice

Mandana Hasanzad
Precision Medicine in Clinical Practice Book PDF

Author : Mandana Hasanzad
Publisher : Springer
Page : 0 pages
File Size : 42,8 Mb
Release : 2022-10-01
Category : Medical
ISBN : 9811950814

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Precision Medicine in Clinical Practice by Mandana Hasanzad Pdf

The book provides complete information on the cornerstones of precision medicine through the omics approach. Clinical applications of genomics and precision medicine have progressed from a theoretical wish list to an impactful force in medical practice.Step-by-step descriptions are provided from basics to the future application and its benefit in clinical practice. Precision medicine aims to personalize health care by tailoring decisions and treatments to each individual in every possible way. Precision medicine includes pharmacogenomics. Essential information is provided on the role of precision medicine and pharmacogenomics in the clinical practice of cancer, cardiovascular disease, diabetes, psychiatric disease, and also the importance for healthcare professionals. This book will assist the practitioners how to integrate precision medicine and pharmacogenomics data into their clinical practice. It is hoped that physicians, pharmacists, and scientists with basic scientific knowledge of precision medicine will findthis book useful.

The Color of Precision Medicine

Shirley Sun,Zoe Ong
The Color of Precision Medicine Book PDF

Author : Shirley Sun,Zoe Ong
Publisher : Taylor & Francis
Page : 162 pages
File Size : 40,8 Mb
Release : 2024-04-23
Category : Social Science
ISBN : 9781040022900

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The Color of Precision Medicine by Shirley Sun,Zoe Ong Pdf

Will genome-based precision medicine fix the problem of race/ethnicity-based medicine? To answer this question, Sun and Ong propose the concept of racialization of precision medicine, defined as the social processes by which racial/ethnic categories are incorporated (or not) into the development, interpretation, and implementation of precision medicine research and practice. Drawing on interview data with physicians and scientists in the field of cancer care, this book addresses the following questions: Who are the racializers in precision medicine, how and why do they do it? Under what conditions do clinicians personalize medical treatments in the context of cancer therapies? The chapters elucidate different ways in which racialization occurs and reveal that there exists an inherent contradiction in the usage of race/ethnicity as precision medicine moves from bench to bedside. The relative resources theory is proposed to explain that whether race/ethnicity-based medicine will be replaced by genomic medicine depends on the resources available at the individual and systemic levels. Furthermore, this book expands on how racialization happens not only in pharmacogenomic drug efficacy studies, but also in drug toxicity studies and cost-effectiveness studies. An important resource for clinicians, researchers, public health policymakers, health economists, and journalists on how to deracialize precision medicine.