The Color Of Precision Medicine

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The Color of Precision Medicine

Shirley Sun,Zoe Ong
The Color of Precision Medicine Book PDF

Author : Shirley Sun,Zoe Ong
Publisher : Taylor & Francis
Page : 162 pages
File Size : 46,9 Mb
Release : 2024-04-23
Category : Social Science
ISBN : 9781040022900

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The Color of Precision Medicine by Shirley Sun,Zoe Ong Pdf

Will genome-based precision medicine fix the problem of race/ethnicity-based medicine? To answer this question, Sun and Ong propose the concept of racialization of precision medicine, defined as the social processes by which racial/ethnic categories are incorporated (or not) into the development, interpretation, and implementation of precision medicine research and practice. Drawing on interview data with physicians and scientists in the field of cancer care, this book addresses the following questions: Who are the racializers in precision medicine, how and why do they do it? Under what conditions do clinicians personalize medical treatments in the context of cancer therapies? The chapters elucidate different ways in which racialization occurs and reveal that there exists an inherent contradiction in the usage of race/ethnicity as precision medicine moves from bench to bedside. The relative resources theory is proposed to explain that whether race/ethnicity-based medicine will be replaced by genomic medicine depends on the resources available at the individual and systemic levels. Furthermore, this book expands on how racialization happens not only in pharmacogenomic drug efficacy studies, but also in drug toxicity studies and cost-effectiveness studies. An important resource for clinicians, researchers, public health policymakers, health economists, and journalists on how to deracialize precision medicine.

The Color of Precision Medicine

Shirley Hsiao-Li Sun,Zoe Ong
The Color of Precision Medicine Book PDF

Author : Shirley Hsiao-Li Sun,Zoe Ong
Publisher : Unknown
Page : 0 pages
File Size : 47,8 Mb
Release : 2024
Category : Medical
ISBN : 1032565586

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The Color of Precision Medicine by Shirley Hsiao-Li Sun,Zoe Ong Pdf

This book proposes the concept of racialization of precision medicine, defined as the social processes by which racial/ethnic categories are incorporated (or not) into the development, interpretation and implementation of precision medicine research and practice. An important resource on how to deracialize precision medicine

Precision Medicine

Hans-Peter Deigner,Matthias Kohl
Precision Medicine Book PDF

Author : Hans-Peter Deigner,Matthias Kohl
Publisher : Academic Press
Page : 376 pages
File Size : 52,7 Mb
Release : 2018-02-15
Category : Medical
ISBN : 9780128054338

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Precision Medicine by Hans-Peter Deigner,Matthias Kohl Pdf

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation Encompasses easy access to relevant approaches, interactions and original literature

Bayesian Precision Medicine

Peter F. Thall
Bayesian Precision Medicine Book PDF

Author : Peter F. Thall
Publisher : CRC Press
Page : 330 pages
File Size : 49,8 Mb
Release : 2024-05-07
Category : Mathematics
ISBN : 9781040026663

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Bayesian Precision Medicine by Peter F. Thall Pdf

Bayesian Precision Medicine presents modern Bayesian statistical models and methods for identifying treatments tailored to individual patients using their prognostic variables and predictive biomarkers. The process of evaluating and comparing treatments is explained and illustrated by practical examples, followed by a discussion of causal analysis and its relationship to statistical inference. A wide array of modern Bayesian clinical trial designs are presented, including applications to many oncology trials. The later chapters describe Bayesian nonparametric regression analyses of datasets arising from multistage chemotherapy for acute leukemia, allogeneic stem cell transplantation, and targeted agents for treating advanced breast cancer. Features: Describes the connection between causal analysis and statistical inference Reviews modern personalized Bayesian clinical trial designs for dose-finding, treatment screening, basket trials, enrichment, incorporating historical data, and confirmatory treatment comparison, illustrated by real-world applications Presents adaptive methods for clustering similar patient subgroups to improve efficiency Describes Bayesian nonparametric regression analyses of real-world datasets from oncology Provides pointers to software for implementation Bayesian Precision Medicine is primarily aimed at biostatisticians and medical researchers who desire to apply modern Bayesian methods to their own clinical trials and data analyses. It also might be used to teach a special topics course on precision medicine using a Bayesian approach to postgraduate biostatistics students. The main goal of the book is to show how Bayesian thinking can provide a practical scientific basis for tailoring treatments to individual patients.

Biomarkers, Diagnostics and Precision Medicine in the Drug Industry

Abdel Halim
Biomarkers Diagnostics and Precision Medicine in the Drug Industry Book PDF

Author : Abdel Halim
Publisher : Academic Press
Page : 294 pages
File Size : 42,6 Mb
Release : 2019-06-08
Category : Medical
ISBN : 9780128161227

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Biomarkers, Diagnostics and Precision Medicine in the Drug Industry by Abdel Halim Pdf

The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline, as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerate the time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. This book aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies, which includes standard-of-care approved assays as well as for-investigational-use and for-research-use-only assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. This book serves as a reference to drug developers, IVD providers, clinical labs, healthcare givers, academicians, and researchers for best practices to help increase the probability of success in drug development and improve patient management. Provides the unique insight of an expert with extensive experience in diagnostics and clinical laboratory on one side and drug discovery and development on the other side Addresses the challenges of drug development and precision medicine and suggests how to eliminate or mitigate these challenges through better utilization of biomarkers and diagnostics in drug development and patient management Features case studies and real-life examples from different classes of biomarkers on different platforms for different therapeutic areas and includes more than 200 illustrations

The Road from Nanomedicine to Precision Medicine

Shaker. A Mousa,Raj Bawa,Gerald F. Audette
The Road from Nanomedicine to Precision Medicine Book PDF

Author : Shaker. A Mousa,Raj Bawa,Gerald F. Audette
Publisher : CRC Press
Page : 646 pages
File Size : 44,8 Mb
Release : 2020-01-06
Category : Medical
ISBN : 9781000043327

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The Road from Nanomedicine to Precision Medicine by Shaker. A Mousa,Raj Bawa,Gerald F. Audette Pdf

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Precision Medicine

David B. Teplow
Precision Medicine Book PDF

Author : David B. Teplow
Publisher : Academic Press
Page : 298 pages
File Size : 52,8 Mb
Release : 2022-08-23
Category : Science
ISBN : 9780323997850

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Precision Medicine by David B. Teplow Pdf

Precision Medicine, Volume 190 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Evolution of Biomarkers and Strategies for Integrating the Precision Philosophy to Guide Monitoring of Individualized Autoimmunity Conditions and to Implement the Philosophy into Clinical Practice, Precision Medicine in Epilepsy, The use of ASOs for personized medicine, Adult medicine, EGFR, NF-KB signal and regulatory noncoding RNAs in cancer, Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis, The Paradox of Personalized Medicine, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Molecular Biology and Translational Science series Updated release includes the latest information on the precision medicine

Biosensors in Precision Medicine

Laís Canniatti Brazaca,Juliane Renata Sempionatto
Biosensors in Precision Medicine Book PDF

Author : Laís Canniatti Brazaca,Juliane Renata Sempionatto
Publisher : Elsevier
Page : 409 pages
File Size : 48,6 Mb
Release : 2024-02-13
Category : Science
ISBN : 9780443153815

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Biosensors in Precision Medicine by Laís Canniatti Brazaca,Juliane Renata Sempionatto Pdf

Biosensors in Precision Medicine: From Fundamentals to Future Trends covers important topics regarding biomarkers, including biomarker discovery, validation, application in precision medicine, the principles of biosensors, their use in precision medicine, important analytical parameters, recent advances in bioreceptors and transduction, and more. Finally, the hottest trends of biosensors in precision medicine, including lab-on-a-chip and wearable devices, advances towards telemedicine, machine learning, artificial intelligence and the commerciality of these devices are discussed. Provides a timely review of the state-of-the-art developments in biosensors and their applications in precision medicine Presents an evaluation of case studies, along with real-life examples Addresses recent trends on biosensors for precision medicine

Personalized and Precision Medicine Informatics

Terrence Adam,Constantin Aliferis
Personalized and Precision Medicine Informatics Book PDF

Author : Terrence Adam,Constantin Aliferis
Publisher : Springer Nature
Page : 349 pages
File Size : 51,6 Mb
Release : 2019-09-17
Category : Medical
ISBN : 9783030186265

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Personalized and Precision Medicine Informatics by Terrence Adam,Constantin Aliferis Pdf

This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals.

AI and IoT-Based Technologies for Precision Medicine

Khang, Alex
AI and IoT Based Technologies for Precision Medicine Book PDF

Author : Khang, Alex
Publisher : IGI Global
Page : 585 pages
File Size : 44,9 Mb
Release : 2023-10-18
Category : Medical
ISBN : 9798369308776

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AI and IoT-Based Technologies for Precision Medicine by Khang, Alex Pdf

In the post-COVID-19 healthcare landscape, the demand for smart healthcare solutions and precision medicine systems has grown significantly. To address these challenges, the book AI and IoT-Based Technologies for Precision Medicine provides a comprehensive resource for doctors, researchers, engineers, and students. By leveraging AI and IoT technologies, the book equips healthcare professionals with advanced tools and methodologies for predictive disease analysis, informed decision-making, and other aspects of precision medicine. This resource bridges the gap between theory and practice, exploring concepts like machine learning, deep learning, computer vision, AI-integrated applications, IoT-based technologies, healthcare data analytics, and biotechnology applications. Through this, the book empowers healthcare practitioners to pioneer innovative solutions that enhance efficiency, accuracy, and security in medical practices. AI and IoT-Based Technologies for Precision Medicine not only offer insights into the potential of AI-powered applications and IoT-equipped techniques in smart healthcare but also foster collaboration among healthcare scholars and professionals. This authoritative guide encourages knowledge sharing and collaboration to harness the transformative potential of AI and IoT, leading to revolutionary advancements in medical practices and healthcare services. With this book as a guide, readers can navigate the evolving landscape of high-tech medicine, taking confident steps toward a cutting-edge and precise medical ecosystem.

Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine

Kristen Reynolds,Roland Valdes
Pharmacogenomics and Precision Medicine An Issue of the Clinics in Laboratory Medicine Book PDF

Author : Kristen Reynolds,Roland Valdes
Publisher : Elsevier Health Sciences
Page : 177 pages
File Size : 41,9 Mb
Release : 2016-08-16
Category : Medical
ISBN : 9780323462808

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Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine by Kristen Reynolds,Roland Valdes Pdf

This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.

Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book

Gregory J. Tsongalis
Current Topics in Molecular Diagnostics and Precision Medicine An Issue of the Clinics in Laboratory Medicine E Book Book PDF

Author : Gregory J. Tsongalis
Publisher : Elsevier Health Sciences
Page : 217 pages
File Size : 44,6 Mb
Release : 2022-11-12
Category : Medical
ISBN : 9780443183119

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Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book by Gregory J. Tsongalis Pdf

In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Precision Medicine in Cancer Therapy

Daniel D. Von Hoff,Haiyong Han
Precision Medicine in Cancer Therapy Book PDF

Author : Daniel D. Von Hoff,Haiyong Han
Publisher : Springer
Page : 283 pages
File Size : 53,6 Mb
Release : 2019-06-17
Category : Medical
ISBN : 9783030163914

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Precision Medicine in Cancer Therapy by Daniel D. Von Hoff,Haiyong Han Pdf

This book presents the latest advances in precision medicine in some of the most common cancer types, including hematological, lung and breast malignancies. It also discusses emerging technologies that are making a significant impact on precision medicine in cancer therapy. In addition to describing specific approaches that have already entered clinical practice, the book explores new concepts and tools that are being developed. Precision medicine aims to deliver personalized healthcare tailored to a patient’s genetics, lifestyle and environment, and cancer therapy is one of the areas in which it has flourished in recent years. Documenting the latest advances, this book is of interest to physicians and clinical fellows in the front line of the war on cancer, as well as to basic scientists working in the fields of cancer biology, drug development, biomarker discovery, and biomedical engineering. The contributing authors include translational physicians with first-hand experience in precision patient care.

Can precision medicine be personal; Can personalized medicine be precise?

Y. Michael Barilan,Margherita Brusa,Aaron Ciechanover
Can precision medicine be personal Can personalized medicine be precise Book PDF

Author : Y. Michael Barilan,Margherita Brusa,Aaron Ciechanover
Publisher : Oxford University Press
Page : 353 pages
File Size : 43,9 Mb
Release : 2022-02-10
Category : Medical
ISBN : 9780192608680

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Can precision medicine be personal; Can personalized medicine be precise? by Y. Michael Barilan,Margherita Brusa,Aaron Ciechanover Pdf

People have always sought medical care that is tailored to every individual patient. Alongside with the historical development of institutions of care, the vision of personal and 'holistic' care persisted. Patient-centred medicine, interpersonal communication and shared decision making have become central to medical practice and services. This evolving vision of 'personalized medicine' is in the forefront of medicine, creating debates among ethicists, philosophers and sociologists of medicine about the nature of disease and the definition of wellness, the impact on the daily life of patients, as well as its implications on low-income countries. Is increased 'precision' also an improvement on the personal aspects of care or erosion of privacy? Do 'precise' and 'personalized' approach marginalize public health, and can this care be personalized without attention to culture, economy and society? The book provides a multidisciplinary and interdisciplinary discussion of the ethos and ethics of precision/personal medicine, involving scientists who have shaped the field, in dialogue with ethicists, social scientists and philosophers of science. The contributing scholars come from all over the world and from different cultural backgrounds providing reflective perspectives of history of ideas, critical theory and technology assessment, together with the actual work done by pioneers in the field. It explores issues such as global justice, gender, public health, pharmaceutical industry, international law and religion, and explores themes discussed in relation to personalized medicine such as new-born screening and disorders of consciousness. This book will be of interest to academicians in bioethics, history of medicine, social sciences of medicine as well as general educated readers.

Handbook of Biomarkers and Precision Medicine

Claudio Carini,Mark Fidock,Alain van Gool
Handbook of Biomarkers and Precision Medicine Book PDF

Author : Claudio Carini,Mark Fidock,Alain van Gool
Publisher : CRC Press
Page : 631 pages
File Size : 50,8 Mb
Release : 2019-04-16
Category : Mathematics
ISBN : 9780429576737

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Handbook of Biomarkers and Precision Medicine by Claudio Carini,Mark Fidock,Alain van Gool Pdf

"The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work." -Maria Freire, Foundation for the National Institutes of Health Handbook of Biomarkers and Precision Medicine provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development. Features: Detailed insights into biomarker discovery, validation and diagnostic development with implementation strategies Lessons-learned from successful Precision Medicine case studies A variety of exciting and emerging biomarker technologies The next frontiers and future challenges of biomarkers in Precision Medicine Claudio Carini, Mark Fidock and Alain van Gool are internationally recognized as scientific leaders in Biomarkers and Precision Medicine. They have worked for decades in academia and pharmaceutical industry in EU, USA and Asia. Currently, Dr. Carini is Honorary Faculty at Kings’s College School of Medicine, London, UK. Dr. Fidock is Vice President of Precision Medicine Laboratories at AstraZeneca, Cambridge, UK. Prof.dr. van Gool is Head Translational Metabolic Laboratory at Radboud university medical school, Nijmegen, NL.