Glucocorticoids

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 45,6 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : N.J. Goulding,Roderick Flower
Publisher : Birkhäuser
Page : 205 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783034883481

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Glucocorticoids by N.J. Goulding,Roderick Flower Pdf

Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorticoid biology from the seminal description of glucocorticoid insufficiency by Thomas Addison in the mid-19th century, up to current advances in elucidating the molecular basis of glucocorticoid action. Important discoveries are presented, as well as milestones in drug development, a survey of current clinical practice, and prospects for novel glucocorticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.

Author : Ntambwe Malangu
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 51,8 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9781789231380

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Pharmacokinetics and Adverse Effects of Drugs by Ntambwe Malangu Pdf

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.

Author : George M. Hall,Jennifer M. Hunter,Mark S. Cooper
Publisher : Cambridge University Press
Page : 203 pages
File Size : 47,7 Mb
Release : 2010-04-01
Category : Medical
ISBN : 9781139486125

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Core Topics in Endocrinology in Anaesthesia and Critical Care by George M. Hall,Jennifer M. Hunter,Mark S. Cooper Pdf

Core Topics in Endocrinology in Anesthesia and Critical Care provides a comprehensive, practical overview of the perioperative management of patients with endocrine disorders, giving clear diagnostic advice and management guidelines. This book considers the management of patients with endocrine disorders of the pituitary, thyroid, parathyroid and adrenal glands, including rarer disorders such as MEN syndrome. It then considers all aspects of the perioperative management of diabetic patients, including paediatric, obstetric and ambulatory patients. Finally it discusses endocrine disorders in the critically ill patient, covering such issues as the topical conundrum of glucose control and the management of diabetic metabolic acidosis, thyroid storm and myxoedema coma. Every chapter reviews the relevant anatomy and pathophysiology and the latest developments in defining the genetic causes are also considered where appropriate. Core Topics in Endocrinology in Anesthesia and Critical Care is an invaluable tool for all anaesthetists and intensivists in their daily clinical practice.

Author : Bone and Tooth Society
Publisher : Royal College of Physicians
Page : 66 pages
File Size : 54,6 Mb
Release : 2002
Category : Glucocorticoids
ISBN : 9781860161735

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Glucocorticoid-induced Osteoporosis by Bone and Tooth Society Pdf

Author : Paolo Sassone-Corsi,Yves Christen
Publisher : Springer
Page : 132 pages
File Size : 47,5 Mb
Release : 2016-04-04
Category : Medical
ISBN : 9783319270692

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A Time for Metabolism and Hormones by Paolo Sassone-Corsi,Yves Christen Pdf

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Author : Andrea Giustina,Alberto Angeli,Ernesto Canalis
Publisher : Karger Medical and Scientific Publishers
Page : 213 pages
File Size : 54,6 Mb
Release : 2002
Category : Medical
ISBN : 9783805572965

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Glucocorticoid-induced Osteoporosis by Andrea Giustina,Alberto Angeli,Ernesto Canalis Pdf

Osteoporosis is one of the most clinically relevant disabling chronic disease encountered in clinical practice. A common cause of osteoporosis is glucocorticoid excess, as glucocorticoids may increase bone resorption, inhibit bone formation, have indirect actions on bone by decreasing intestinal calcium absorption and induce hypercalciuria. This book presents a comprehensive overview of the effects of glucocorticoids on bone metabolism and structure and on the diagnosis and treatment of glucocorticoid-induced osteoporosis. It aims at providing updated information on the pathogenesis, diagnosis and treatment of this often dramatic complication of glucocorticoid excess. Being one of the few publications completely devoted to glucocorticoid-induced osteoporosis it will heighten the awareness of specialists who prescribe glucocorticoids of the clinical relevance of this treatment complication. 'Glucocorticoid-Induced Osteoporosis' is addressed to clinical experts as well as to general practitioners who will both benefit from the comprehensive and integrative view of the management of patients exposed to glucocorticoids.

Author : Jen-Chywan Wang,Charles Harris
Publisher : Springer
Page : 385 pages
File Size : 55,8 Mb
Release : 2015-07-27
Category : Science
ISBN : 9781493928958

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Glucocorticoid Signaling by Jen-Chywan Wang,Charles Harris Pdf

This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.

Author : Graham J. Burton,David J. P. Barker,Ashley Moffett,Kent Thornburg
Publisher : Cambridge University Press
Page : 267 pages
File Size : 53,6 Mb
Release : 2010-12-16
Category : Medical
ISBN : 9781139494229

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The Placenta and Human Developmental Programming by Graham J. Burton,David J. P. Barker,Ashley Moffett,Kent Thornburg Pdf

Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.

Author : Xiaoxiao Qian
Publisher : BoD – Books on Demand
Page : 662 pages
File Size : 49,8 Mb
Release : 2012-11-28
Category : Medical
ISBN : 9789535108726

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Glucocorticoids by Xiaoxiao Qian Pdf

As one class of the most important steroid hormones, glucocorticoids have long been recognised and their therapeutic benefits have been widely used in clinical treatment, especially in anti-inflammation cases. Glucocorticoids regulate various processes in the body including the mobilization of energy stores, immune functions, gene expression, and maintenance of the homeostasis as well as the stress response, this is not surprising that the concept of "glucocorticoids" is mentioned in almost all medical text books that focus on specific organs or systems such as the cardiovascular system, the immune system, and the neuroendocrine system. The book of Glucocorticoids - New Recognition of Our Familiar Friend aims to introduce the latest findings relating to glucocorticoids, either freshly from the laboratory or from clinical case studies, and to open up a new angle of looking at the issue of balancing the therapeutic benefits and side effects brought up by glucocorticoids.

Author : Emira Ayroldi,Claude Libert,Alexandra K. Kiemer
Publisher : Frontiers Media SA
Page : 233 pages
File Size : 44,9 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9782889717439

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Glucocorticoids in Immunity and Inflammation by Emira Ayroldi,Claude Libert,Alexandra K. Kiemer Pdf

Author : Anonim
Publisher : Elsevier
Page : 416 pages
File Size : 50,8 Mb
Release : 2008-09-12
Category : Medical
ISBN : 0080559360

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The Hypothalamus-Pituitary-Adrenal Axis by Anonim Pdf

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.

Author : David R. Riddle
Publisher : CRC Press
Page : 408 pages
File Size : 46,5 Mb
Release : 2007-04-19
Category : Medical
ISBN : 1420005529

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Brain Aging by David R. Riddle Pdf

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Author : Alessandro Peri,Christopher J. Thompson,Joseph G. Verbalis
Publisher : Karger Medical Scientific
Page : 0 pages
File Size : 51,9 Mb
Release : 2019
Category : Hyponatremia
ISBN : 3318063827

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Disorders of Fluid and Electrolyte Metabolism by Alessandro Peri,Christopher J. Thompson,Joseph G. Verbalis Pdf

It is well known that acute, severe hyponatremia is a life-threatening situation. However, there is growing evidence that mild and chronic hyponatremia may also have negative consequences. Gait disturbances, attention deficits, falls and fractures, and bone loss have all been reported, with increased mortality in almost every disease state if the patient is hyponatremic. This book has been written by key opinion leaders in the field and covers a spectrum of crucial aspects of hyponatremia, including a historical perspective, physiology and pathophysiology of water homeostasis, epidemiology of hyponatremia, and clinical features. A detailed description of all available therapies has been incorporated, with a guide to a clinician's approach to key therapeutic situations. Hyponatremia is a topic that encompasses all areas of medicine, so this book will be of interest to specialists such as endocrinologists, nephrologists and internists, but will also be a valuable resource for all clinicians who manage patients with hyponatremia.

Author : Robert Dantzer,Emmanuelle E. Wollmann,Raz Yirmiya
Publisher : Springer Science & Business Media
Page : 334 pages
File Size : 50,6 Mb
Release : 1999-07-31
Category : Medical
ISBN : 9780306461354

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Cytokines, Stress, and Depression by Robert Dantzer,Emmanuelle E. Wollmann,Raz Yirmiya Pdf

Until a few years ago, cytokines were only known to immunologists; now these molecules have burst upon neurosciences and permeated several avenues of current research. This book examines the possible role of cytokines in mental depression, based on recent clinical and experimental data, and constitutes the first attempt to make a synthesis between the exciting new developments in cytokine research and their implications for the pathophysiology of mental disorders.