Pharmacokinetics And Adverse Effects Of Drugs

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Pharmacokinetics and Adverse Effects of Drugs

Author : Ntambwe Malangu
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 47,8 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9781789231380

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Pharmacokinetics and Adverse Effects of Drugs by Ntambwe Malangu Pdf

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.

Pharmacokinetics and Adverse Effects of Drugs - Mechanisms and Risks Factors

Author : Ntambwe Malangu
Publisher : Unknown
Page : 162 pages
File Size : 55,7 Mb
Release : 2018
Category : Therapeutics. Pharmacology
ISBN : 1789231396

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Pharmacokinetics and Adverse Effects of Drugs - Mechanisms and Risks Factors by Ntambwe Malangu Pdf

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 46,5 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Meyler's Side Effects of Drugs

Author : Jeffrey K. Aronson
Publisher : Elsevier
Page : 7629 pages
File Size : 48,9 Mb
Release : 2015-10-15
Category : Medical
ISBN : 9780444537164

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Meyler's Side Effects of Drugs by Jeffrey K. Aronson Pdf

Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. Enhanced encyclopedic format with drug monographs now organized alphabetically Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing Extensive bibliography with over 40,000 references A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company

Drug Benefits and Risks

Author : Christoffel Jos van Boxtel,Budiono Santoso,I. Ralph Edwards
Publisher : IOS Press
Page : 846 pages
File Size : 51,7 Mb
Release : 2008
Category : Medical
ISBN : 9781586038809

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Drug Benefits and Risks by Christoffel Jos van Boxtel,Budiono Santoso,I. Ralph Edwards Pdf

This updated and revised 2nd edition of "Drug Benefits and Risks" is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs, but in this context also highlighting the social impact which drugs have in modern societies. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose, the book covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases; the book gives guidance on how doctors should act so that drugs can be used effectively and safely; and it encourages the rational use of drugs in society.This publication brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.

Stephens' Detection of New Adverse Drug Reactions

Author : John Talbot,Patrick Waller
Publisher : John Wiley & Sons
Page : 776 pages
File Size : 43,7 Mb
Release : 2004-03-08
Category : Medical
ISBN : 047084552X

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Stephens' Detection of New Adverse Drug Reactions by John Talbot,Patrick Waller Pdf

A key text for all those involved in pharmacovigilance. Detection of new adverse drug reactions is fundamental to the protection of patients from harm that may occur as a result of medication. This book explores the methods used to investigate new adverse drug reactions, discussing all elements from the scientific background and animal toxicology through to worldwide regulatory and ethical issues. Stephens' Detection of New Adverse Drug Reactions provides comprehensive and up-to-date coverage of material fundamentally important to all those active in the field, whether they work in the pharmaceutical industry, drug regulatory authorities or in academia. The fifth edition of this classic reference work includes new chapters on: * vaccine safety surveillance * managing drug safety issues with marketed products * operational aspects of drug safety function * safety of biotechnology products * future of pharmacovigilance Reviews of previous editions: "This book surpasses all its educational aims. Not only is the subject matter covered comprehensively but the material is presented in a very user-friendly manner. The editors have succeeded in producing a highly-specific, definitive reference book which doubles as a most enjoyable read." Commended by the 1999 BMA Medical Book Competition "For anyone entering the field of adverse reaction monitoring one could not wish for a better primer" International Journal of Risk and Safety in Medicine

Clinical Pharmacokinetics

Author : Soraya Dhillon,Andrzej Kostrzewski
Publisher : Pharmaceutical Press
Page : 284 pages
File Size : 42,7 Mb
Release : 2006
Category : Chemotherapy
ISBN : 0853695717

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Clinical Pharmacokinetics by Soraya Dhillon,Andrzej Kostrzewski Pdf

Pharmacokinetics is the study of the process of drug absorption, distribution, metabolism and elimination. The aim of applying pharmacokinetic principles is to individualise the dose of drug, and optimise the outcome achieved in each patient. Its application reduces the chance of under-treatment, inadvertent poisoning, and dose related adverse effects. This new edition is specifically aimed at supporting undergraduate studies in pharmacokinetics, and has a strong emphasis on the application of pharmacokinetics in routine clinical practice. Clinical Pharmacokinetics also includes several case studies and 'questions and answers' to further aid understanding and revision.

Introduction to Pharmacokinetics and Pharmacodynamics

Author : Thomas N. Tozer,Malcolm Rowland
Publisher : Lippincott Williams & Wilkins
Page : 342 pages
File Size : 54,5 Mb
Release : 2006
Category : Medical
ISBN : 0781751497

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Introduction to Pharmacokinetics and Pharmacodynamics by Thomas N. Tozer,Malcolm Rowland Pdf

This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Clinical Pharmacokinetics

Author : John E. Murphy
Publisher : ASHP
Page : 433 pages
File Size : 53,8 Mb
Release : 2011-10-01
Category : Medical
ISBN : 9781585283477

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Clinical Pharmacokinetics by John E. Murphy Pdf

In the complex field of pharmacokinetics, one reference guide has an identity all its own: Clinical Pharmacokinetics. Now the fully updated 5th edition brings to experienced practitioners and students alike the fresh information they need most: · Content organized for fast reference to specific drugs · The latest on dosing in obese and overweight patients · Dosing considerations for neonatal, pediatric and geriatric patients · A look at protein binding and its implications · Population values for a variety of drugs to initiate dosing · Drug dosing in renal disease and creatinine clearance estimation A Distinctively Straightforward Guide is Now Even Better The 5th Edition of Clinical Pharmacokinetics is completely revised and updated, making a handy clinical guide even easier to use than ever. · Reorganized content features two sections: Basic Concepts and Special Populations and Specific Drugs and Drug Classes · Sections on special populations, including Dosing in Overweight and Obese Patients, have been conveniently grouped together · Comprehensive introduction covers means, measurements and monitoring · Also conveniently placed up front” a glossary of pharmacokinetics basics and commonly used equations

Side Effects of Drugs Annual

Author : Anonim
Publisher : Elsevier
Page : 692 pages
File Size : 45,6 Mb
Release : 2015-11-26
Category : Medical
ISBN : 9780444635310

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Side Effects of Drugs Annual by Anonim Pdf

Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions was first published in 1977, and has been continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each Annual provides clinicians and medical investigators with a reliable and critical survey of new data and trends in the area of adverse drug reactions and interactions, with an international team of specialists contributing their expertise each year. Provides a critical yearly survey of the new data and trends regarding the side effects of drugs Authored and reviewed by pioneers throughout the world in the clinical and practice sciences Presents an essential clinical on the side effects of drugs for practitioners and healthcare professionals

Adverse Drug Effects

Author : Jennifer Kelly
Publisher : John Wiley & Sons
Page : 224 pages
File Size : 51,5 Mb
Release : 2006-02-03
Category : Medical
ISBN : 9780470031612

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Adverse Drug Effects by Jennifer Kelly Pdf

This practical guide to pharmacology is unusual in its approach. Instead of examining the normal effects of drugs this book looks at the adverse effects. With the advent of nurse prescribing it is essential that nurses are familiar with the common adverse effects, how to recognise them and how to deal with them. The book is divided into three sections. The first examines the pharmacology of drugs i.e. what the body does to drugs (pharmocokinetics), what the drugs do to the body (pharmocodynamics), and how adverse reactions can result from these two processes. Section two looks at putting the scientific knowledge into action through an examination of nurse administration and prescribing, drug development and the issue of patient compliance and empowerment. Section three consists of twelve case studies which describe various scenarios in which there have been adverse drug effects. Throughout the book concepts are explained using examples so that the nurse can relate the concept of adverse effect to the drugs she is familiar with.

Oral Drug Absorption

Author : Jennifer B. Dressman,Christos Reppas
Publisher : CRC Press
Page : 432 pages
File Size : 47,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420077346

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Oral Drug Absorption by Jennifer B. Dressman,Christos Reppas Pdf

Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an

Side Effects of Drugs Annual

Author : Jeffrey K. Aronson
Publisher : Elsevier
Page : 715 pages
File Size : 42,9 Mb
Release : 2011-08-19
Category : Medical
ISBN : 9780080522814

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Side Effects of Drugs Annual by Jeffrey K. Aronson Pdf

The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then, as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has contributed to the Annuals by selecting critically from each year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is misleading. Provides a critical yearly survey of new data and trends Includes an essay that describes the modern approach to classifying adverse drug reactions Special reviews in this Annual include, among other topics: Antipsychotic drugs and now-onset diabetes mellitus, Treating asthma during pregnancy, and MMR vaccine and autism

Drug Transporters

Author : Martin F. Fromm,Richard B. Kim
Publisher : Springer Science & Business Media
Page : 457 pages
File Size : 45,7 Mb
Release : 2010-11-19
Category : Medical
ISBN : 9783642145414

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Drug Transporters by Martin F. Fromm,Richard B. Kim Pdf

It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

Carbamazepine

Author : Luca Gallelli
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 42,7 Mb
Release : 2013
Category : Anticonvulsants
ISBN : 1629480487

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Carbamazepine by Luca Gallelli Pdf

Carbamazepine (CBZ), one of the most used antiepileptic drugs (AEDs), was introduced on the market in the early 1960's and ever since, it has become the most frequently prescribed drug for the treatment of several forms of epilepsy. It is also used to treat other pathologies, such as neuropathic pain and psychiatric disorders. This book provides a detailed description of this drug, evaluating all aspects of its pharmacology. CBZ pharmacokinetics is discussed, with a particular emphasis on its metabolism, side effects and drug interactions. Then the authors focus on its pharmacodynamic effects, and the most recent evidence indicating that CBZ-sodium channel interaction is not specific and ligand-gated ion channels are also affected by the drug. The role of oxacarbazepine, its main metabolite MHD, and other new drugs are explained in detail. Additionally, non-antiepileptic CBZ clinical effects and drug-drug interactions in the elderly under polytherapy are described. In conclusion, the occurrence of carbamazepine in the hydrosphere, its fate and the different technologies available for its remediation are also discussed.