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A dazzling collection of poems by the Pulitzer Prize and T. S. Eliot Prize for Poetry winner, called "a poet for these times, a powerful woman who won’t back down" (San Francisco Chronicle). A collection by the much praised poet whose second book The Dead and the Living, was both the Lamont Poetry Selection for 1983 and winner of the National Book Critics Circle Award.
Game designers today are expected to have an arsenal of multi-disciplinary skills at their disposal in the fields of art and design, computer programming, psychology, economics, composition, education, mythology—and the list goes on. How do you distill a vast universe down to a few salient points? Players Making Decisions brings together the wide range of topics that are most often taught in modern game design courses and focuses on the core concepts that will be useful for students for years to come. A common theme to many of these concepts is the art and craft of creating games in which players are engaged by making meaningful decisions. It is the decision to move right or left, to pass versus shoot, or to develop one’s own strategy that makes the game enjoyable to the player. As a game designer, you are never entirely certain of who your audience will be, but you can enter their world and offer a state of focus and concentration on a task that is intrinsically rewarding. This detailed and easy-to-follow guide to game design is for both digital and analog game designers alike and some of its features include: A clear introduction to the discipline of game design, how game development teams work, and the game development process Full details on prototyping and playtesting, from paper prototypes to intellectual property protection issues A detailed discussion of cognitive biases and human decision making as it pertains to games Thorough coverage of key game elements, with practical discussions of game mechanics, dynamics, and aesthetics Practical coverage of using simulation tools to decode the magic of game balance A full section on the game design business, and how to create a sustainable lifestyle within it
Gold Nanoparticles for Drug Delivery by Prashant Kesharwani Pdf
Gold Nanoparticles for Drug Delivery discusses the synthesis and characterization of gold nanoparticles (AuNPs), presenting an historical introduction to the developments in the area, discussing methods and characterization parameters, covering targeted delivery strategies, treatment of cancer, CNS conditions, infectious diseases, HIV/AIDS infection, wound healing and tissue regeneration, dentistry, gene delivery, and its photo properties used in diagnostic and therapies, and finally presenting regulatory aspects such as theranostic applications, vaccine development, toxicity, and the translation of research to marketable products. This book is a complete reference for researchers in nanotechnology drug delivery and pharmaceutical disciplines. Researchers in pharmaceutical industries, especially those involved in the use of gold nanoparticles in the field of drug delivery, diagnosis, targeted and early therapies will also benefit from this book. Covers gold nanoparticles' characterization and synthesis techniques related to drug delivery Focuses on targeting strategies using gold nanoparticles for efficient drug delivery Provides a consolidated overview of applications of gold nanoparticles for drug delivery to several systems and conditions
Since its introduction in 1971, the development and application of colloidal gold as a marker in electron microscopy has been phenomenal. Colloidal gold has become the method of choice in immunocytochemistry and many areas of cell biology. This universal method is applicable to most microscopical systems including optical microscopy; scanning, transmission, and high voltage electron microscopy; photoelectron, photon, fluorescent darkfield, and epipolarization microscopy. Colloidal gold allows high and low resolution studies, enzyme and nucleic acid labeling, study of dynamic cellular processes, and virus detection. This book is among the first available to cover the principles and methodology of colloidal gold in microscopy. Methods are described step by step, to enable researchers to learn these complex procedures solely by reference to these books Problems and limitations of techniques are discussed Guides users to avoid problems and choose the correct procedures for specific applications Contributors are eminent authorities in their fields
Handbook of Lung Targeted Drug Delivery Systems by Yashwant Pathak,Nazrul Islam Pdf
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems
White Gold (A Dan Taylor spy thriller) by Rachel Amphlett Pdf
A haunted man. A murdered friend. A deadly enemy. Dan Taylor’s career as a bomb disposal expert in the British Army ended when an IED killed three of his team and left him scarred for life. Years later, and on the brink of self-destruction, Dan struggles to cope with the nightmares that haunt him. Until the day an estranged friend leaves a voicemail message, moments before he is assassinated in cold blood. Plunged into a global conspiracy, Dan must unravel the research notes Peter Edgewater left behind and locate an explosive device being smuggled towards London by a secretive organisation hell-bent on protecting its assets – and time is running out. White Gold is the first book in an action-packed spy thriller series that fans of Vince Flynn, Robert Ludlum and the Lee Child Jack Reacher series are calling "a blast!” The Dan Taylor spy thriller series: The Legacy Device (A Dan Taylor short story) White Gold Under Fire Three Lives Down Behind the Wire What reviewers are saying about the Dan Taylor spy thriller series: ‘The style is reflective of the thrillers of Robert Ludlum... a heart-pumping page-turning thriller.’ Goodreads 'There have been many thrillers coming out in the market today and, from time to time, we find one that completely catches our attention. White Gold is certainly one of them!' Readers Favourites 'A gripping story that keeps you on the edge of your seat. Get the audio book version it's awesome. I can't recommend it enough' Goodreads 'From the explosive opening, to the thrilling ending it had me hooked. It's a fascinating fast moving story.' Goodreads Spy novels, spy books, spy series, British spy book series, British spy books, espionage books, espionage book series, action and adventure books, thriller books, crime fiction, crime fiction books, fast paced books, page turning read, espionage, military, action, suspense, crime thriller, thriller, mystery, London, Singapore, thriller series, mystery series, thriller and suspense, vigilante justice, crime, action packed, private investigators, secret agents, suspense series, spies, tech, techno, technology, crime, financial, murder, theft, murder, assassin, death, deadly, gun, killer, sniper, shot, deadly, crime fiction, crime novel, kidnapping, book series, women's fiction, conspiracy, political, terrorism, contemporary, genre fiction, Lee Child, Jack Reacher, Reacher, John Sandford, Robert Ludlum, Jason Bourne, contract killer, Jack Ryan, Robert Crais, Killing Eve, 24, Spooks, MI6, James Bond, Ian Fleming
Supramolecular Gold Chemistry by Rodolphe Antoine Pdf
This book is about supramolecular gold chemistry. This book provides a unique international forum aimed at covering a broad description of results involving the supramolecular chemistry of gold with a special focus on the gold–sulfur interface leading to hybrid materials ranging from gold–thiolate complexes to thiolate-protected gold nanoclusters and gold–thiolate supramolecular assemblies or nanoparticles. The role of thiolates on the structure and optical features of gold nanohybrid systems (ranging from plasmonic gold nanoparticles and fluorescent gold nanoclusters to self-assembled Au-containing thiolated coordination polymers) is highlighted in the 12 papers presented in this book.
Spherical nucleic acids (SNAs) comprise a nanoparticle core, and a densely packed and highly oriented nucleic acid shell. They have novel structure-dependent properties that differ from those of linear nucleic acids and that makes them useful in chemistry, biology, the life sciences, medicine, materials science, and engineering. This book is a reprint volume that compiles 101 key papers that have been published by the Mirkin Group at Northwestern University, USA, and their collaborators over the past more than two decades. Volume 1 provides an overview and a historical framework of SNAs and discusses their enabling features, which set them apart from all other forms of matter. Volume 2 covers the general design rules for colloidal crystal engineering with DNA, spanning the building blocks and DNA- and RNA-based "programmable bonds" that can be utilized in preparing such structures. Volume 3 continues the discussion of colloidal crystallization processes and routes to hierarchical assembly, featuring dynamic nanoparticle superlattices and lattices prepared on surfaces or via templating strategies, and explores what one can uniquely learn from and do with colloidal crystals prepared from nucleic acid–functionalized nanomaterials in optics, plasmonics, and catalysis. Volume 4 covers the role of SNAs in biomedicine, especially as diagnostic probes both inside and outside of cells, and treatments based on gene regulation and immunotherapy.
