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Guidelines For The Clinical Evaluation Of Antidepressant Drugs Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Guidelines For The Clinical Evaluation Of Antidepressant Drugs book. This book definitely worth reading, it is an incredibly well-written.
Author : United States. Food and Drug Administration. Bureau of Drugs
Publisher : Unknown
Page : 24 pages
File Size : 48,9 Mb
Release : 1977
Category : Antidepressants
ISBN : MINN:31951003051193H
Author : United States. Food and Drug Administration,United States. Food and Drug Administration. Bureau of Drugs
Publisher : Unknown
Page : 24 pages
File Size : 46,7 Mb
Release : 1977
Category : Anxiety
ISBN : MINN:319510030512026
Author : Graziano Pinna
Publisher : Unknown
Page : 412 pages
File Size : 43,5 Mb
Release : 2015-04-01
Category : Electronic
ISBN : 1634820762
Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.
Author : American Psychiatric Association
Publisher : American Psychiatric Publishing
Page : 368 pages
File Size : 43,7 Mb
Release : 1996
Category : Medical
ISBN : 0890423067
The aim of the American Psychiatric Association Practice Guideline series is to improve patient care. Guidelines provide a comprehensive synthesis of all available information relevant to the clinical topic. Practice guidelines can be vehicles for educating psychiatrists, other medical and mental health professionals, and the general public about appropriate and inappropriate treatments. The series also will identify those areas in which critical information is lacking and in which research could be expected to improve clinical decisions. The Practice Guidelines are also designed to help those charged with overseeing the utilization and reimbursement of psychiatric services to develop more scientifically based and clinically sensitive criteria.
Author : United States. Food and Drug Administration. Bureau of Drugs
Publisher : Unknown
Page : 20 pages
File Size : 40,7 Mb
Release : 1977
Category : Drugs
ISBN : STANFORD:24501026232
Author : United States. Food and Drug Administration. Bureau of Drugs
Publisher : Unknown
Page : 28 pages
File Size : 50,8 Mb
Release : 1977
Category : Drugs
ISBN : UOM:39015003205070
Author : United States. Food and Drug Administration
Publisher : Unknown
Page : 28 pages
File Size : 44,5 Mb
Release : 1977
Category : Chemotherapy
ISBN : MINN:31951003051182M
Author : Gary M. Matoren
Publisher : CRC Press
Page : 584 pages
File Size : 43,8 Mb
Release : 2020-08-18
Category : Business & Economics
ISBN : 9781000148718
This book examines the sequence of events and methodology in the industrial clinical research process; a reference for multidisciplinary personnel. It is the conceptual framework involving the philosophical, economic, political, historical, regulatory, planning, and marketing aspects of the process.
Author : United States. Department of Health, Education, and Welfare
Publisher : Unknown
Page : 606 pages
File Size : 54,7 Mb
Release : 1978
Category : Government publications
ISBN : WISC:89054170618
Author : United States. Department of Health and Human Services
Publisher : Unknown
Page : 596 pages
File Size : 44,9 Mb
Release : 2024-06-30
Category : Government publications
ISBN : STANFORD:36105219361255
Author : United States. Department of Health, Education, and Welfare
Publisher : Unknown
Page : 596 pages
File Size : 52,8 Mb
Release : 1978
Category : Education
ISBN : OSU:32435019444389
Author : Karl E. Peace
Publisher : CRC Press
Page : 387 pages
File Size : 43,9 Mb
Release : 2017-09-19
Category : Mathematics
ISBN : 9781351414449
This book is a compilation of topics addressed by the ASA Biopharmaceutical Section work groups, including the etiology and evolution of the work groups, the work group guidelines and structure, and the statistical issues associated with clinical trials in clinical drug development programs.
Author : United States. Superintendent of Documents
Publisher : Unknown
Page : 1228 pages
File Size : 49,9 Mb
Release : 1978
Category : Government publications
ISBN : UCR:31210024274605
February issue includes Appendix entitled Directory of United States Government periodicals and subscription publications; September issue includes List of depository libraries; June and December issues include semiannual index
Author : Anonim
Publisher : Unknown
Page : 44 pages
File Size : 40,8 Mb
Release : 1977
Category : Electronic
ISBN : MINN:31951D00860231G
Author : United States. Congress. Senate. Select Committee on Small Business
Publisher : Unknown
Page : 830 pages
File Size : 43,7 Mb
Release : 1980
Category : Legislative hearings
ISBN : UCAL:B3608386
