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The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs” in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.
Nutrient Requirements of Laboratory Animals, by National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition Pdf
In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Sasspants, a guinea pig, reluctantly agrees to act as a private investigator when Hamisher the hamster begs for her help in discovering who is stealing sandwiches from the pet shop's befuddled owner.
Guinea pigs are a popular pet, a cute but dim friend for those who seek an alternative to dogs and cats. They are increasingly bred for looks, shaped by humans to a so-called ideal appearance. But it was guinea pigs that shaped humans from as early as 5000 BC, when their domestication began a long and fruitful relationship, influencing scientists such as William Harvey, and painters from Jan Brueghel to Beatrix Potter. Guinea pigs have been the center of countless works of art and literature, inspiring children and adults in addition to their utility as pets. Dorothy Yamamoto s "Guinea Pig" is the first of its kind to take an in-depth look at the storied history of guinea pig and human interaction. The author reveals the history and personality of an animal that is not often given much attention beyond its cute and cuddly nature, giving the guinea pig a historical voice that has been much-overlooked. "
The authoritative information and advice you need, illustrated throughout with full-color photographs--now revised and redesigned to be even more reader-friendly! * An illustrated look at colors and breeds * The story of how guinea pigs were domesticated * Advice on selecting a guinea pig * Pointers on feeding, grooming, and health * Tips on understanding guinea pig behavior * Fun activities to enjoy with your guinea pig
Going, Going, Dragon!: Book 6 by Colleen AF Venable Pdf
Sasspants, Hamisher, and company have never had it so good. Now that Mr. Venezi's Pets and Stuff doesn't actually sell pets, everybody has time to explore other interests. There's scuba diving in the fish tank with the Steves, theatrical performances with the mice, and walrus toothbrushes and aardvark neckties for everyone! It's not all good times, though. Mr. Venezi's been mistaking his bills for fan mail and a dragon may have moved into the shop. Can Sasspants and Hamisher ensure that a "happily ever after" is in store for the animals, Mr. Venezi, Viola...and even that nice lady from the bookshop next door?
Author : Virginia C. G. Richardson Publisher : John Wiley & Sons Page : 137 pages File Size : 47,7 Mb Release : 2011-10-14 Category : Medical ISBN : 9781118250341
Diseases of Domestic Guinea Pigs by Virginia C. G. Richardson Pdf
This book provides a comprehensive text covering all aspects of guinea pig medicine. This updated edition will be of value to veterinary surgeons and students, veterinary nurses, breeders and all those working in the animal care industry. Written in note form the book assists in the formulation of a diagnostic plan when the practitioner is faced with a sick animal. Sections on clinical signs, diagnoses and treatments, allow rapid reference in successive chapters on the reproductive, digestive, respiratory, musculoskeletal and urinary systems, the skin, head and neck, nervous system and husbandry. All the latest drug information has been included and full details of dose rates, contraindications and components of the proprietary preparations are listed in chapter 11. A new chapter has been written providing information on herbal and homeopathic remedies.
The beloved character Harry the Dirty Dog returns in this brand-new picture book! A fun story to share with all dog fans, as well as guinea pig families and classrooms. Harry, the mischievous little white dog with black spots, isn’t happy when the children are paying more attention to the neighbor’s guinea pig than him. But when Harry accidentally causes the guinea pig to get loose at school, he has to use his detective skills to save the day. Can Harry find the guinea pig before he’s sent to the doghouse? Created in the style of Gene Zion and Margaret Bloy Graham, this is an irresistible story featuring a classic picture book character—perfect for young dog lovers and fans of Harry the Dirty Dog! Gene Zion and Margaret Bloy Graham’s Harry the Dirty Dog has been recognized by the National Education Association as an all-time top-100 children's book. It has also been welcomed by a new generation at home, as Betty White's 2020 reading of the story on StorylineOnline has been viewed more than 8 million times.
The Guinea Pigs is a chilling fable about dehumanization and alienation representing Vaculik's vision of the menace of Soviet domination in the wake of the 1969 invasion. Written in 1970, it is a sweeping condemnation of totalitarianism, embedded in a rich, imaginative, highly experimental narrative. In the words of the New York Review of Books it is "one of the major works of literature produced in postwar Europe."