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Handbook of Acute Leukemia by Wolfgang Hiddemann Pdf
This book provides an overview of the key developments in both acute lymphocytic leukemia and acute myeloid leukemia with a comprehensive guide to the epidemiology, pathogenesis, etiology, clinical manifestations, classification, diagnosis, and staging as well as the most recent developments in the therapeutic landscape for acute leukemia. The Handbook of Acute Leukemia offers readers a key resource into the future outlook for patients with leukemia and is edited and authored by internationally renowned experts in the field. Leukemia is cancer of the white blood cells and acute leukemia means the condition progresses rapidly and aggressively, requiring immediate treatment. Acute leukemia is classified according to the type of white blood cells that are affected: either lymphocytes and myeloid cells.
Acute Leukemia: An Illustrated Guide to Diagnosis and Treatment provides a comprehensive and concise visual reference on acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) seen in children and adults. This book addresses all aspects of AML and ALL including their risk factors, cytogenetics and mutational characteristics, diagnoses, clinical management and prognoses which are imperative and challenging for medical students, residents, hematology and medical oncology fellows, and even community oncologists and hematologists. It presents complex information relying predominantly on pictorial depictions rather than traditional text in a visually instructive format. It replaces the wordiness of a traditional textbook with original and adapted illustrations, instructive schemata and diagrams, photomicrographs, tables, detailed figure legends, and practical, 'bite-sized' text. The result is a visually engaging book that is easy to read, review, and remember. Crafted by world experts in the field, this digestible volume provides you with the must-know information that you can utilize when encountering AML and ALL patients who require immediate attention. Whether you are an early-career practitioner looking for quick guidance to managing a deadly disease or you are a seasoned clinician looking for a quick review of treatment protocols, this engaging format provides a unique and 'go-to' resource. KEY FEATURES Contains over 40 tables and over 220 illustrations, histologic photomicrographs, flow diagrams, graphs, and schemata with detailed figure legends Presents complex scientific aspects such as cytogenetics and molecular mutations in a visually digestible and easy-to-understand format Provides helpful and evidence-based treatment recommendations when providing induction therapy, consolidation therapy, and bone marrow transplantation Includes unique chapters on managing psychosexual issues accompanying AML and ALL treatment as well as on the FDA drug development and clinical trial design process Includes digital access to the ebook as well as an online Image Bank
Acute Leukemia by Ashkan Emadi, MD, PhD,Judith E. Karp, MD Pdf
Acute Leukemia: An Illustrated Guide to Diagnosis and Treatment provides a comprehensive and concise visual reference on acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) seen in children and adults. This book addresses all aspects of AML and ALL including their risk factors, cytogenetics and mutational characteristics, diagnoses, clinical management and prognoses which are imperative and challenging for medical students, residents, hematology and medical oncology fellows, and even community oncologists and hematologists. It presents complex information relying predominantly on pictorial depictions rather than traditional text in a visually instructive format. It replaces the wordiness of a traditional textbook with original and adapted illustrations, instructive schemata and diagrams, photomicrographs, tables, detailed figure legends, and practical, ‘bite-sized’ text. The result is a visually engaging book that is easy to read, review, and remember. Crafted by world experts in the field, this digestible volume provides you with the must-know information that you can utilize when encountering AML and ALL patients who require immediate attention. Whether you are an early-career practitioner looking for quick guidance to managing a deadly disease or you are a seasoned clinician looking for a quick review of treatment protocols, this engaging format provides a unique and ‘go-to’ resource. Key Features: Contains over 40 tables and over 220 illustrations, histologic photomicrographs, flow diagrams, graphs, and schemata with detailed figure legends Presents complex scientific aspects such as cytogenetics and molecular mutations in a visually digestible and easy-to-understand format Provides helpful and evidence-based treatment recommendations when providing induction therapy, consolidation therapy, and bone marrow transplantation Includes unique chapters on managing psychosexual issues accompanying AML and ALL treatment as well as on the FDA drug development and clinical trial design process Includes digital access to the e-book as well as an online Image Bank
Acute Promyelocytic Leukemia by Oussama Abla,Francesco Lo Coco,Miguel A. Sanz Pdf
This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges. Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.
Author : Gregory H. Reaman,Franklin O. Smith Publisher : Springer Science & Business Media Page : 330 pages File Size : 50,7 Mb Release : 2011-01-18 Category : Medical ISBN : 9783642137815
Childhood Leukemia by Gregory H. Reaman,Franklin O. Smith Pdf
This book is a comprehensive and up-to-date compendium on all aspects of childhood leukemia. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike.
Leukemia is a group of cancer, which occurs in the bone marrow and results in abnormal growth of white blood cells. Such cells are called blasts or leukemia cells. Bleeding and bruising, fever, tiredness and increased infections are some of the symptoms of leukemia. It can be classified as chronic lymphocytic leukemia, acute lymphoblastic leukemia, acute myeloid leukemia and chronic myeloid leukemia. The diagnosis of leukemia is usually determined by blood tests or though a bone marrow biopsy. A variety of factors may contribute to its incidence, among which are smoking, genetics, chemical exposure, etc. Leukemia is treated with a multi-drug chemotherapy regimen, pharmaceutical medication or with radiation therapy. A bone marrow transplant is also an important strategy to treat such a cancer. This book provides comprehensive insights into leukemia. It consists of contributions made by international experts. Coherent flow of topics, student-friendly language and extensive use of examples make this book an invaluable source of knowledge.
NCCN Guidelines for Patients® Acute Myeloid Leukemia by National Comprehensive Cancer Network® (NCCN®) Pdf
[OFFICIAL CURRENT VERSION] From the National Comprehensive Cancer Network® (NCCN®), comes this essential guide to acute myeloid leukemia. Adapted from clinical treatment guidelines used by physicians and oncology professionals around the world, these NCCN Guidelines for Patients help prepare patients and caregivers to talk with their doctors and make treatment decisions. Topics include: leukemia basics; testing for AML; treatment options; treatment phases; treatment guides for APL, AML, and BPDCN; and making treatment decisions. Let this authoritative handbook be your guide!
This issue of Emerging Cancer Therapeutics provides a comprehensive review for practitioners on the current status of leukemia treatment. Leukemia treatment has undergone major change over the course of the past few years and Leukemia addresses current best practices in the light of the most recent evidence. With contributions from experts across the US and Canada, Leukemia details the current management of different types of leukemia and reviews new therapies in development for various forms of acute leukemia, chronic leukemia, myelodysplastic syndrome, and myeloproliferative disorders. Coverage includes new developments in hematopoitic cell transplantation, leukemia pathology and management, immunotherapy and targeted therapies. It is a valuable tool for clinicians, nurses, researchers, medical students, residents, and fellows. Emerging Cancer Therapeutics Series Titles Features: Editorial board of nationally recognized experts across the spectrum of Cancer Therapeutics In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Cancer Therapeutics Issues edited by an authority in specific subject area Focuses on major topics in Cancer Therapeutics with in-depth articles covering advances in clinical and translational research developments, as well as clinical applications and experience Emphasizes multidisciplinary approaches to research and practice
Handbook of Multiple Myeloma by Mohamad Mohty,Jean-Luc Harousseau Pdf
This handbook is an in-depth and comprehensive guide to the pathophysiology, diagnosis, staging, treatment and management of patients with multiple myeloma. The Handbook was commissioned to address an unmet need for a book of this kind in the myeloma field and to provide busy healthcare professionals with an informative and educational review of the current and emerging treatment recommendations for multiple myeloma. Myeloma is a type of bone marrow cancer arising from plasma cells and is the second most common form of bone marrow cancer, but represents just 1% of all cancers. The causes of myeloma are not fully understood but it is thought to be caused by an interaction of both genetic and environmental factors. This Handbook discusses these issues as well the latest developments in the field and will be an invaluable source of topical information for all healthcare professionals with an interest in multiple myeloma.
The Handbook of Acute Lymphoblatic Leukemia Breakthrough by Dr Bruce Prada Pdf
Embark on a transformative journey through the realms of Acute Lymphoblastic Leukemia (ALL) with our groundbreaking masterpiece, the "Handbook of Acute Lymphoblastic Leukemia Breakthrough. " As we dive into the intricate world of ALL, each chapter unveils a cascade of knowledge that empowers both patients and healthcare professionals alike. UNVEILING THE LANDSCAPE OF ALL KNOWLEDGE Delve deep into the very fabric of ALL - from its definition and classification to the epidemiology, causes, and precursors. Understand the pathophysiology, decode symptoms, and witness the clinical presentation that demands our attention. This chapter sets the stage for an enlightening journey. DIAGNOSTIC MASTERY UNVEILED Explore the art of diagnosis through bone marrow aspirations, blood tests, and cutting-edge imaging methods. Grasp the significance of molecular and cytogenetic testing, paving the way for a precise and distinctive diagnosis that can make all the difference. DECODING ALL SUBTYPES Unravel the mysteries of T-Cell ALL with predictive elements and molecular markers. Gain insights into the genetic nuances that distinguish subtypes, providing a roadmap for tailored treatments and prognostic strategies. CONQUERING ALL - MANAGEMENT UNLEASHED Navigate through the seas of chemotherapy procedures, induction care, consolidation therapy, and specialized treatments. Witness the revolutionary potential of hematopoietic stem cell transplantation and other assistive healthcare measures. Enter the realm of new and experimental therapies that hold promise for a brighter future. TACKLING INTRICACIES HEAD-ON Equip yourself with the tools to combat infections, hematologic issues, thrombocytopenia, and non-hematologic problems. Confront challenges such as organ infiltration and metabolic complications head-on, armed with the knowledge to mitigate risks and enhance patient outcomes. TRIUMPH AND LONG-TERM AFTERCARE Discover the triumphs and challenges in ALL survivorship. Navigate late-life effects, prioritize quality of life, and explore psychosocial support mechanisms. Witness the power of observation and vigilant care in securing a brighter, healthier future. PAVING THE FUTURE FOR ALL Embark on a journey into the future with advancements in molecular biology, groundbreaking CAR-T cell treatments, and the promise of personalized medicine. Explore the realm of observational studies and cooperative research, laying the foundation for optimism and progress. THE VERDICT: A CALL TO ACTION As we conclude this odyssey, synthesize the wealth of knowledge gained and embrace optimism for the future. Our handbook is not just a book - it's a lifeline, an indispensable guide for ALL warriors, caregivers, and medical professionals. Take charge, spread awareness, and join hands in the fight against ALL. ACT NOW: EMPOWERMENT BEGINS HERE This handbook is more than a collection of breakthroughs; it's a call to action. Empower yourself, share this knowledge, and together, let's shape a future where Acute Lymphoblastic Leukemia is not just battled but conquered. The journey to triumph begins with your commitment - take the first step today.
Oxford Handbook of Acute Medicine by Punit Ramrakha,Kevin Moore,Amir Sam Pdf
Current, comprehensive, and focused, the bestselling Oxford Handbook of Acute Medicine returns for its fourth edition. Thoroughly revised and updated throughout, this trusted, quick-reference guide includes the latest evidence-based guidelines and recommended management of medical emergencies alongside new figures and clinical tips from experienced authors and a team of dedicated specialist reviewers. With a new chapter on acute medicine and the older patient, and even more distilled key points and practice tips, it is accessible to all members of the multidisciplinary team and practitioners across an even wider range of specialties. The Oxford Handbook of Acute Medicine remains the must-have resource for all those dealing with acute illness. Your practical guide to the presentation, causes, and management of the acutely ill patient, this Handbook will take you step-by-step through the management of the patient while awaiting specialist help, and beyond, with details of specialist treatments to help you make an informed decision about your patients' ongoing care.
Handbook of Hematologic Malignancies by David A. Sallman, MD,Ateefa Chaudhury, MD,Johnny Nguyen, MD,Ling Zhang, MD,Alan F. List, MD Pdf
Handbook of Hematologic Malignancies provides a unique, practical, and concise guide focused on the must-know points of diagnosis, prognosis, therapeutic management, and cutting edge clinical trial opportunities for each hematologic malignancy. With an ever-increasing growth of evidence and a significant expansion of available treatment options for patients with hematologic disease, remaining current and up-to-date can be extremely challenging for practicing clinicians. This comprehensive subspecialty handbook is designed and organized for the busy hematologist, hematologic oncologist, hematopathologist, and trainee in mind. Every chapter is richly illustrated with color figures and flow diagrams, and contains helpful tables on differential diagnosis, prognostic scoring systems and therapeutic options. A concise case-based review for testing pathologic diagnosis and clinical knowledge for each chapter is included for digital download online and in the e-book. Written by experienced clinicians at the world-renowned Moffitt Cancer Center in Tampa, Florida, as well as contributions from leading academicians throughout the country, this handbook is an essential resource for anyone diagnosing, treating, or managing patients with hematologic malignancy. KEY FEATURES: Contains clear prognostic and diagnostic tools (e.g., tables/flow diagrams/pathology images) with emphasis on key differential diagnoses and diagnostic dilemmas Easy to use treatment recommendations with bullet point format and key references. Discusses the future of patient management based on practice changing clinical trials Includes access to digitally downloadable case-based clinical scenarios and questions with high resolution pathology images linked to each individual chapter
The EBMT/EHA CAR-T Cell Handbook by Nicolaus Kröger,John Gribben,Christian Chabannon,Ibrahim Yakoub-Agha,Hermann Einsele Pdf
This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.
