Handbook Of Bioseparations

Author : Satinder Ahuja
Publisher : Elsevier
Page : 740 pages
File Size : 46,6 Mb
Release : 2000-06-23
Category : Technology & Engineering
ISBN : 9780080507798

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Handbook of Bioseparations by Satinder Ahuja Pdf

It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments

Author : Ganapathy Subramanian
Publisher : Wiley-VCH
Page : 220 pages
File Size : 54,9 Mb
Release : 1998-07
Category : Biotechnology
ISBN : 3527288775

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Bioseparation and Bioprocessing by Ganapathy Subramanian Pdf

Author : Gunter Jagschies,Gail K. Sofer,Lars Hagel
Publisher : Elsevier
Page : 382 pages
File Size : 41,5 Mb
Release : 2007-12-08
Category : Science
ISBN : 0080554512

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Handbook of Process Chromatography by Gunter Jagschies,Gail K. Sofer,Lars Hagel Pdf

This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers. Updates include: - sources and productivity - types of products made today - experiences in clinical and licensed products - economics - current status of validation - illustrations and tables - automated column packing - automated systems New topics include: - the use of disposables - multiproduct versus dedicated production - design principles for chromatography media and filters - ultrafiltration principles and optimization - risk assessments - characterization studies - design space - platform technologies - process analytical technologies (PATs) - biogenerics - comparability assessments Key Features: - new approaches to process optimiaztion - use of patform technologies - applying risk assessment to process design

Author : Paul A. Belter,E. L. Cussler,Wei-Shou Hu
Publisher : Wiley-Interscience
Page : 392 pages
File Size : 51,8 Mb
Release : 1988-02-22
Category : Science
ISBN : UOM:39015012755750

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Bioseparations by Paul A. Belter,E. L. Cussler,Wei-Shou Hu Pdf

Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing.

Author : Roger G. Harrison,Paul Todd,Scott R. Rudge,Demetri P. Petrides
Publisher : Topics in Chemical Engineering
Page : 577 pages
File Size : 43,7 Mb
Release : 2015
Category : Technology & Engineering
ISBN : 9780195391817

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Bioseparations Science and Engineering by Roger G. Harrison,Paul Todd,Scott R. Rudge,Demetri P. Petrides Pdf

Preceded by: Bioseparations science and engineering / Roger G. Harrison ... [et al.]. c2003.

Author : K. Scott
Publisher : Elsevier
Page : 904 pages
File Size : 45,7 Mb
Release : 1995-12-20
Category : Technology & Engineering
ISBN : 0080532896

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Handbook of Industrial Membranes by K. Scott Pdf

This manual contains necessary and useful information and data in an easily accessible format relating to the use of membranes. Membranes are among the most important engineering components in use today, and each year more and more effective uses for membrane technologies are found - for example: water purification, industrial effluent treatment, solvent dehydration by per-vaporation, recovery of volatile organic compounds, protein recovery, bioseparations and many others. The pace of change in the membrane industry has been accelerating rapidly in recent years, occasioned in part by the demand of end-users, but also as a result of the investment in R&D by manufacturers. To reflect these changes the author has obtained the latest information from some of the leading suppliers in the business. In one complete volume this unique handbook gives practical guidance to using selected membrane processes in individual industries while also providing a useful guide to equipment selection and usage.

Author : Raja Ghosh
Publisher : World Scientific Publishing Company
Page : 284 pages
File Size : 46,9 Mb
Release : 2006-10-23
Category : Technology & Engineering
ISBN : 9789813106765

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Principles of Bioseparations Engineering by Raja Ghosh Pdf

Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.

Author : Giorgio Carta,Alois Jungbauer
Publisher : John Wiley & Sons
Page : 440 pages
File Size : 41,8 Mb
Release : 2020-06-02
Category : Science
ISBN : 9783527346660

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Protein Chromatography by Giorgio Carta,Alois Jungbauer Pdf

An all-in-one practical guide on how to efficiently use chromatographic separation methods Based on a training course that teaches the theoretical as well as practical aspects of protein bioseparation to bioprocess professionals, this fully updated and revised new edition offers comprehensive coverage of continuous chromatography and provides readers with many relevant examples from the biopharmaceutical industry. Divided into two large parts, Protein Chromatography: Process Development and Scale-Up, Second Edition presents all the necessary knowledge for effective process development in chromatographic bioseparation, both on small and large scale. The first part introduces chromatographic theory, including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Chapters look at: Downstream Processing of Biotechnology Products; Chromatography Media; Laboratory and Process Columns and Equipment; Adsorption Equilibrium; Rate Processes; and Dynamics of Chromatography Columns. The book closes with chapters on: Effects of Dispersion and Rate Processes on Column Performance; Gradient Elution Chromatography; and Chromatographic Column Design and Optimization. -Presents the most pertinent examples from the biopharmaceutical industry, including monoclonal antibodies -Provides an overview of the field along with design tools and examples illustrating the advantages of continuous processing in biopharmaceutical productions -Focuses on process development and large-scale bioseparation tasks, making it an ideal guide for the professional bioengineer in the biotech and pharma industries -Offers field-tested information based on decades of training courses for biotech and chemical engineers in Europe and the U.S. Protein Chromatography: Process Development and Scale-Up, Second Edition will appeal to biotechnologists, analytical chemists, chromatographers, chemical engineers, pharmaceutical industry, biotechnological industry, and biochemists.

Author : Paul A. Belter,Cussler Belter (Hu, P.A, E. L., Wei-Shou)
Publisher : Unknown
Page : 384 pages
File Size : 54,6 Mb
Release : 1988
Category : Electronic
ISBN : 8126531975

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Bioseparations by Paul A. Belter,Cussler Belter (Hu, P.A, E. L., Wei-Shou) Pdf

Author : Timothy C. Frank,Bruce S. Holden
Publisher : Walter de Gruyter GmbH & Co KG
Page : 354 pages
File Size : 48,5 Mb
Release : 2023-08-07
Category : Technology & Engineering
ISBN : 9783110695137

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Industrial Chemical Separation by Timothy C. Frank,Bruce S. Holden Pdf

A fresh new treatment written by industry insiders, this work gives readers a remarkably clear view into the world of chemical separation. The authors review distillation, extraction, adsorption, crystallization, and the use of membranes – providing historical perspective, explaining key features, and offering insights from personal experience. The book is for engineers and chemists with current or future responsibility for chemical separation on a commercial scale – in its design, operation, or improvement – or for anyone wanting to learn more about chemical separation from an industrial point of view. The result is a compelling survey of popular technologies and the profession, one that brings the art and craft of chemical separation to life. Ever wonder how popular separation technologies came about, how a particular process functions, or how mass transfer units differ from theoretical stages? Or perhaps you want some pointers on how to begin solving a separation problem. You will find clear explanations and valuable insights into these and other aspects of industrial practice in this refreshing new survey.

Author : Ladisch
Publisher : Unknown
Page : 128 pages
File Size : 50,7 Mb
Release : 2002-02-01
Category : Electronic
ISBN : 0471231940

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Bioseparations Engineering by Ladisch Pdf

Author : Abhinav A. Shukla,Mark R. Etzel,Shishir Gadam
Publisher : CRC Press
Page : 600 pages
File Size : 46,9 Mb
Release : 2006-07-07
Category : Medical
ISBN : 9781420016024

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Process Scale Bioseparations for the Biopharmaceutical Industry by Abhinav A. Shukla,Mark R. Etzel,Shishir Gadam Pdf

The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceut

Author : Paul Cutler
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 42,5 Mb
Release : 2008-02-02
Category : Science
ISBN : 9781592596553

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Protein Purification Protocols by Paul Cutler Pdf

The first edition of Protein Purification Protocols (1996), edited by Professor Shawn Doonan, rapidly became very successful. Professor Doonan achieved his aims of p- ducing a list of protocols that were invaluable to newcomers in protein purification and of significant benefit to established practitioners. Each chapter was written by an ex- rienced expert in the field. In the intervening time, a number of advances have w- ranted a second edition. However, in attempting to encompass the recent developments in several areas, the intention has been to expand on the original format, retaining the concepts that made the initial edition so successful. This is reflected in the structure of this second edition. I am indebted to Professor Doonan for his involvement in this new edition and the continuity that this brings. Each chapter that appeared in the original volume has been reviewed and updated to reflect advances and bring the topic into the 21st century. In many cases, this reflects new applications or new matrices available from vendors. Many of these have increased the performance and/or scope of the given method. Several new chapters have been introduced, including chapters on all the currently used protein fractionation and ch- matographic techniques. They introduce the theory and background for each method, providing lists of the equipment and reagents required for their successful execution, as well as a detailed description of how each is performed.

Author : Daniel Forciniti
Publisher : Wiley-Blackwell
Page : 326 pages
File Size : 43,6 Mb
Release : 2008-07-01
Category : Science
ISBN : 9780813820859

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Industrial Bioseparations by Daniel Forciniti Pdf

Industrial Bioseparations offers comprehensive coverage of bioseparations including all unit operations. This new book offers a careful balance between the fundamentals of bioseparations processing and the practical applications in industry today. It is laid out in a methodical way with preliminary chapters covering general approaches to bioseparations for commercially important biomacromolecules, thermodynamics and mass transfer principles, and following chapters addressing unit operations such as filtration and chromatography. Lab experiments are included which emphasize obtaining scale up parameters as well as commonly used operating conditions are included.

Author : John R. Dean
Publisher : John Wiley and Sons
Page : 298 pages
File Size : 54,9 Mb
Release : 2003-04-18
Category : Science
ISBN : 0470844213

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Methods for Environmental Trace Analysis by John R. Dean Pdf

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