Handbook Of Drug Analysis

Author : Fred Smith
Publisher : Elsevier
Page : 584 pages
File Size : 42,9 Mb
Release : 2004-12-31
Category : Law
ISBN : 0080472893

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Handbook of Forensic Drug Analysis by Fred Smith Pdf

The Handbook of Forensic Drug Analysis is a comprehensive chemical and analytic reference for the forensic analysis of illicit drugs. With chapters written by leading researchers in the field, the book provides in-depth, up-to-date methods and results of forensic drug analyses. This Handbook discusses various forms of the drug as well as the origin and nature of samples. It explains how to perform various tests, the use of best practices, and the analysis of results. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. Topics range from the use of immunoassay technologies for drugs-of-abuse testing, to methods of forensic analysis for cannabis, hallucinogens, cocaine, opioids, and amphetamine. The book also looks at synthetic methods and law enforcement concerns regarding the manufacture of illicit drugs, with an emphasis on clandestine methamphetamine production. This Handbook should serve as a widely used reference for forensic scientists, toxicologists, pharmacologists, drug companies, and professionals working in toxicology testing labs, libraries, and poison control centers. It may also be used by chemists, physicians and those in legal and regulatory professions, and students of graduate courses in forensic science. Contributed to by leading scientists from around the world The only analysis book dedicated to illicit drugs of abuse Comprehensive coverage of sampling methods and various forms of analysis

Author : Satinder Ahuja,Stephen Scypinski
Publisher : Academic Press
Page : 604 pages
File Size : 40,8 Mb
Release : 2010-11-11
Category : Medical
ISBN : 9780123759818

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Handbook of Modern Pharmaceutical Analysis by Satinder Ahuja,Stephen Scypinski Pdf

Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS

Author : Ray H. Liu,Daniel E. Gadzala
Publisher : Unknown
Page : 400 pages
File Size : 41,8 Mb
Release : 1997
Category : Law
ISBN : UOM:39015043808081

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Handbook of Drug Analysis by Ray H. Liu,Daniel E. Gadzala Pdf

Covers preliminary test and chromatographic methods in forensic drug testing. Reviews identification methods such as molecular spectrophotometry, nuclear magnetic resonance, and mass spectrometry. Discusses the fundamental relationship between instrumentation and drug analysis. Evaluates the characteristics and pretreatment approaches for common sample categories. Presents in-depth test result interpretation on issues commonly encountered in workplace drug urinalysis. Analyzes and compares performance characteristics of immunoassays commonly used for workplace drug urinalysis.

Author : Ramakrishna Seethala,Prabhavathi Fernandes
Publisher : CRC Press
Page : 619 pages
File Size : 53,8 Mb
Release : 2001-07-24
Category : Medical
ISBN : 9780824741440

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Handbook of Drug Screening by Ramakrishna Seethala,Prabhavathi Fernandes Pdf

A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.

Author : Osamu Suzuki,Kanako Watanabe
Publisher : Springer Science & Business Media
Page : 653 pages
File Size : 48,9 Mb
Release : 2006-01-16
Category : Medical
ISBN : 9783540275794

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Drugs and Poisons in Humans by Osamu Suzuki,Kanako Watanabe Pdf

Unique analysis of drugs and poisons to facilitate testing in all laboratories even by inexperienced chemists Includes source of chemicals needed for the experiments Texts are composed by 67 experts in analyzing the respective compounds Clear and uniform structure of chapters for ease of reading The text is illustrated by many diagrams and tables

Author : Amitava Dasgupta
Publisher : Springer Science & Business Media
Page : 441 pages
File Size : 41,7 Mb
Release : 2007-10-23
Category : Medical
ISBN : 9781588297808

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Handbook of Drug Monitoring Methods by Amitava Dasgupta Pdf

Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.

Author : Eustace George Coverley Clarke
Publisher : Unknown
Page : 680 pages
File Size : 42,6 Mb
Release : 2004
Category : Analytical toxicology
ISBN : UOM:39015058787154

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Clarke's Analysis of Drugs and Poisons by Eustace George Coverley Clarke Pdf

This manual and reference work provides a source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material. Volume One contains 32 chapters covering the practice of and analytical procedures used in forensic toxicology. Volume Two contains over 1750 drug and related substance monographs detailing: physical properties; analytical methods; pharmacokinetic data; and toxicity data, as well as expanded indexes and appendices. These volumes should be useful for all forensic and crime laboratories, toxicologists and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.

Author : Satinder Ahuja,Stephen Scypinski
Publisher : Elsevier
Page : 587 pages
File Size : 47,5 Mb
Release : 2001-08-02
Category : Medical
ISBN : 9780080488929

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Handbook of Modern Pharmaceutical Analysis by Satinder Ahuja,Stephen Scypinski Pdf

This book describes the role modern pharmaceutical analysis plays in the development of new drugs. Detailed information is provided as to how the quality of drug products is assured from the point of discovery until the patient uses the drug. Coverage includes state-of-the-art topics such as analytics for combinatorial chemistry and high-throughput screening, formulation development, stability studies, international regulatory aspects and documentation, and future technologies that are likely to impact the field. Emphasis is placed on current, easy-to-follow methods that readers can apply in their laboratories. No book has effectively replaced the very popular text, Pharmaceutical Analysis, that was edited in the 1960s by Tak Higuchi. This book will fill that gap with an up-to-date treatment that is both handy and authoritative.

Author : Amitava Dasgupta
Publisher : Springer Science & Business Media
Page : 446 pages
File Size : 52,6 Mb
Release : 2007-10-05
Category : Medical
ISBN : 9781597450317

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Handbook of Drug Monitoring Methods by Amitava Dasgupta Pdf

Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.

Author : Satinder Ahuja,Michael Dong
Publisher : Elsevier
Page : 679 pages
File Size : 49,5 Mb
Release : 2005-02-09
Category : Medical
ISBN : 9780080455181

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Handbook of Pharmaceutical Analysis by HPLC by Satinder Ahuja,Michael Dong Pdf

High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Author : Jeri D. Ropero-Miller,Bruce A. Goldberger,Ray H. Liu
Publisher : American Association for Clinical Chemistry, Incorporated
Page : 485 pages
File Size : 49,5 Mb
Release : 2009
Category : Chemistry, Forensic
ISBN : 1594250901

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Handbook of Workplace Drug Testing by Jeri D. Ropero-Miller,Bruce A. Goldberger,Ray H. Liu Pdf

The Second Edition of Handbook of Workplace Drug Testing builds on the knowledge included in the first edition and offers considerable updates and enhancements. It remains a valuable resource for understanding the complexity of the science, law, and interpretation of workplace drug testing. The information that has been compiled in the second edition was obtained through extensive laboratory study and literature surveys. As leaders in their fields, the authors provide a historical perspective of workplace drug testing, analytical procedures and theory, drug class overviews and stability of drugs, adulteration and specimen validity testing, alternative matrices, quality assurance and quality control, result interpretation for medical review officers, and laboratory accreditation. This book is a "must have" for all workplace drug testing laboratories and practitioners in forensic toxicology, clinical toxicology, and clinical chemistry. A complete subject index is included for easy referencing of topics.

Author : Lena Ohannesian,Anthony Streeter
Publisher : CRC Press
Page : 605 pages
File Size : 43,7 Mb
Release : 2001-11-09
Category : Medical
ISBN : 9780824741945

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Handbook of Pharmaceutical Analysis by Lena Ohannesian,Anthony Streeter Pdf

Exploring the analysis of pharmaceuticals, including polymorphic forms, this book discusses regulatory requirements in pharmaceutical product development and pharmaceutical testing. It covers methods of drug separation and procedures such as capillary electrophoresis for chromatographic separation of molecules. Additional topics include drug formulation analysis using vibrational and magnetic resonance spectroscopy and identification of drug metabolites and decomposition products using such techniques as mass spectrometry. The book provides more than 300 tables, equations, drawings, and photographs, and convenient, easy-to-use indices, facilitating quick access to each topic.

Author : Ashraf Mozayani,Lionel Raymon
Publisher : Springer Science & Business Media
Page : 662 pages
File Size : 54,6 Mb
Release : 2003-10-15
Category : Medical
ISBN : 9781592596546

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Handbook of Drug Interactions by Ashraf Mozayani,Lionel Raymon Pdf

A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Author : Georg Hempel
Publisher : Elsevier
Page : 379 pages
File Size : 52,8 Mb
Release : 2004-05-15
Category : Science
ISBN : 9780080530543

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Drug Monitoring and Clinical Chemistry by Georg Hempel Pdf

Drug Monitoring and Clinical Chemistry, the 5th volume in the Handbook of Analytical Separations series, gives an overview about methods to analyse drugs in biological fluids. The most widely used methods to analyse drugs in biological fluids. i.e. chromatographic methods, CE and immunoassays are described in detail. For important drugs, an overview about the methods available and a comparison of the techniques should be given to enable the reader to choose the right method depending on laboratory equipment, staff, the aim of the investigation etc. Other general aspects important for conducting therapeutic drug monitoring or pharmacokinetics studies are also covered, i.e. sample preparation, validation of the analytical methods and pharmacokinetic methods for interpreting the data. Areas where therapeutic drug monitoring is used frequently such as antibiotics, immunosuppressant drugs, antipsychotic and anticancer drugs will be discussed in detail. In addition, the important field of phenotyping and genotyping for therapy optimisation with special focus on real-life applications is also covered. The book contains important information for analyst working on drug analysis in clinical chemistry, hospital pharmacists involved in therapeutic drug monitoring, other pharmacists, chemists or physicians working on pharmacokinetic studies in industry or academia. In contrast to other books in this field, this book provides up-to-date information regarding both methodology and clinical applications. For the applications, only fields are described where therapeutic drug monitoring is used in clinical routine and provides benefit to the patients. Overview of all important field where therapeutic drug monitoring is applied All relevant analytical and computational methods are discussed Written by experts with a lot of practical experience in the field

Author : Ray H. Liu,Bruce A. Goldberger
Publisher : American Association for Clinical Chemistry, Incorporated
Page : 408 pages
File Size : 42,5 Mb
Release : 1995
Category : Business & Economics
ISBN : UOM:39015035754798

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Handbook of Workplace Drug Testing by Ray H. Liu,Bruce A. Goldberger Pdf