Handbook Of Lipid Membranes

Author : Cyrus R. Safinya,Joachim Radler
Publisher : CRC Press
Page : 371 pages
File Size : 49,9 Mb
Release : 2021-09-14
Category : Medical
ISBN : 9781466555730

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Handbook of Lipid Membranes by Cyrus R. Safinya,Joachim Radler Pdf

This handbook provides a unique overview of lipid membrane fundamentals and applications. The fascinating world of lipids that harbor and govern so many biological functionalities are discussed within the context of membrane structures, interactions, and shape evolution. Beyond the fundamentals in lipid science, this handbook focuses on how scientists are building bioinspired biomimetic systems for applications in medicine, cosmetics, and nanotechnology. Key Features: Includes experimental and theoretical overviews on the role of lipids, with or without associated biomolecules, as structural components imparting distinct membrane shapes and intermembrane interactions Covers the mechanisms of lipid-membrane curvature, by peptide and protein binding, and the roles of signalling lipids and the cytoskeleton in plasma membrane shape evolution Covers advanced X-ray and force measurement techniques Discusses applications in biomedicine, cosmetics, and nanotechnology, including lipid vectors in nucleic acid, drug delivery in dermal applications, and lipid-based sensors and artificial biointerfaces Covers artificial membranes from block copolymers, synthetic copolypeptides, and recombinant proteins Includes an exciting section that explores the role of lipids in the origin of life in hydrothermal conditions This book is a highly informative companion for professionals in biophysics, biochemistry, physical chemistry, and material and pharmaceutical sciences and bioengineering.

Author : Derek Marsh
Publisher : CRC Press
Page : 1176 pages
File Size : 51,6 Mb
Release : 2013-02-15
Category : Science
ISBN : 9781420088328

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Handbook of Lipid Bilayers, Second Edition by Derek Marsh Pdf

Now in its second edition, the Handbook of Lipid Bilayers is a groundbreaking work that remains the field’s definitive text and only comprehensive source for primary physicochemical data relating to phospholipid bilayers. Along with basic thermodynamic data, coverage includes both dynamic and structural properties of phospholipid bilayers. It is an indispensable reference for users of bilayer model membranes and liposome delivery systems and for those interested in the biophysics of membrane structure. Each chapter in the second edition contains considerable amounts of explanation and elaboration, including, in many cases, extensive analysis of structural connections between the data. New in the Second Edition: Chapters on crystal structures of phospholipids include new structures and more comprehensive data on bond lengths, bond angles, and torsion angles—and all coordinates are Cartesian Wide-angle data is indexed whenever possible to characterize chain-packing modes in gel and crystalline lamellar phases Low-angle data are analyzed in terms of the lipid and water thicknesses Headgroup separations in electron density profiles for phospholipids are included, and a separate section is devoted to the in-depth analysis of electron density profiles that provides the most detailed structural information on fluid lamellar phases Phase diagrams of phospholipid mixtures are vastly expanded and have been redrawn in standardized format to aid intercomparison. Cholesterol, including ternary systems, is now featured. New sections on titration calorimetry, and much extended data on the temperature dependence of transfer rates The greatly expanded chapter on bilayer–bilayer interactions features new and detailed information on the components of interbilayer pressures

Author : Derek Marsh
Publisher : CRC Press
Page : 1174 pages
File Size : 50,7 Mb
Release : 2020-07-02
Category : Electronic
ISBN : 0367576554

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Handbook of Lipid Bilayers by Derek Marsh Pdf

Now in its second edition, the Handbook of Lipid Bilayers is a groundbreaking work that remains the field's definitive text and only comprehensive source for primary physicochemical data relating to phospholipid bilayers. Along with basic thermodynamic data, coverage includes both dynamic and structural properties of phospholipid bilayers. It is an indispensable reference for users of bilayer model membranes and liposome delivery systems and for those interested in the biophysics of membrane structure. Each chapter in the second edition contains considerable amounts of explanation and elaboration, including, in many cases, extensive analysis of structural connections between the data. New in the Second Edition: Chapters on crystal structures of phospholipids include new structures and more comprehensive data on bond lengths, bond angles, and torsion angles--and all coordinates are Cartesian Wide-angle data is indexed whenever possible to characterize chain-packing modes in gel and crystalline lamellar phases Low-angle data are analyzed in terms of the lipid and water thicknesses Headgroup separations in electron density profiles for phospholipids are included, and a separate section is devoted to the in-depth analysis of electron density profiles that provides the most detailed structural information on fluid lamellar phases Phase diagrams of phospholipid mixtures are vastly expanded and have been redrawn in standardized format to aid intercomparison. Cholesterol, including ternary systems, is now featured. New sections on titration calorimetry, and much extended data on the temperature dependence of transfer rates The greatly expanded chapter on bilayer-bilayer interactions features new and detailed information on the components of interbilayer pressures

Author : Derek Marsh
Publisher : Springer
Page : 408 pages
File Size : 51,7 Mb
Release : 1990-10-24
Category : Science
ISBN : UOM:39015018892193

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Hdbk of Lipid Bilayers by Derek Marsh Pdf

Author : R. Lipowsky,E. Sackmann
Publisher : Elsevier
Page : 537 pages
File Size : 50,7 Mb
Release : 1995-06-15
Category : Technology & Engineering
ISBN : 9780080541914

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Structure and Dynamics of Membranes by R. Lipowsky,E. Sackmann Pdf

The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Author : Frank D. Gunstone,John L. Harwood,Fred B. Padley
Publisher : CRC Press
Page : 1311 pages
File Size : 47,7 Mb
Release : 1994-07-21
Category : Science
ISBN : 9780412433207

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The Lipid Handbook, Second Edition by Frank D. Gunstone,John L. Harwood,Fred B. Padley Pdf

A great deal of research has been carried out on this important class of compounds in the last ten years. To ensure that scientists are kept up to date, the editors of the First Edition of The Lipid Handbook have completely reviewed and extensively revised their highly successful original work. The Lipid Handbook: Second Edition is an indispensable resource for anyone working with oils, fats, and related substances.

Author : Rajendra Prasad
Publisher : Springer Science & Business Media
Page : 272 pages
File Size : 41,5 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783642798375

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Manual on Membrane Lipids by Rajendra Prasad Pdf

Although previously thought to be merely passive structural components, membrane lipids have recently been found to be actively involved in cellular transport and signal transduction processes. Clear protocols for the study of membrane lipid properties, cellular transport or signal transduction are presented in this manual. Following a short introduction to membrane lipids, techniques for the isolation and extraction of membrane fractions, the analysis of the lipid composition, lipid turnover, and the involvement in signal transduction as well as the preparation of liposomes are described.

Author : Gregor Cevc
Publisher : CRC Press
Page : 1162 pages
File Size : 54,8 Mb
Release : 1993-08-02
Category : Science
ISBN : 0824790502

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Phospholipids Handbook by Gregor Cevc Pdf

Employing a multidisciplinary approach to phospholipid research, this work catalogues the current knowledge of this class of molecules and details the general, chemical, physical and structural properties of phospholipid monolayers and bilayers. Phospholipid applications are also covered.

Author : Charles G. Cranfield
Publisher : Unknown
Page : 300 pages
File Size : 48,6 Mb
Release : 2022
Category : Electronic books
ISBN : 1071618431

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Membrane Lipids by Charles G. Cranfield Pdf

This detailed book explores examples of current in vitro and in silico techniques that are at the forefront of lipid membrane research today. Beginning with methods and strategies associated with the creation and use of lipid membrane models in various research settings, the volume continues with electrical impedance spectroscopy strategies and methods to identify how ions and proteins interact with model lipid bilayers, guidance on lipid bilayer in silico molecular dynamics modeling, novel techniques to explore lipid bilayer characteristics using neutron scattering, IR spectroscopy, and atomic force microscopy (AFM), as well as unique fluorescence techniques. Written in the highly successful Methods in Molecular Biology series style, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Membrane Lipids: Methods and Protocols serves as an ideal guide for researchers seeking to further investigate the often complicated world of lipid membrane biophysics.

Author : Danilo D. Lasic,Yechezkel Barenholz
Publisher : CRC Press
Page : 350 pages
File Size : 42,5 Mb
Release : 1996-01-09
Category : Science
ISBN : 0849347319

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Handbook of Nonmedical Applications of Liposomes by Danilo D. Lasic,Yechezkel Barenholz Pdf

Liposomes have become an important model in fundamental biomembrane research, including biophysical, biochemical, and cell biological studies of membranes and cell function. They are thoroughly studied in several applications, such as drug delivery systems in medical applications and as controlled release systems, microencapsulating media, signal carriers, support matrices, and solubilizers in other applications. While medical applications have been extensively reviewed in recent literature, there is a need for easily accessible information on applications for liposomes beyond pharmacology and medicine. The Handbook of Nonmedical Applications of Liposomes fills this void. This unique new handbook series presents recent developments in the use of liposomes in many scientific disciplines, from studies on the origin of life, protein function, and vesicle shapes, to applications in cosmetics, diagnostics, ecology, bioreclamation, and the food industry. In these volumes many of the top experts contribute extensive reviews of their work.

Author : R. Lipowsky,E. Sackmann
Publisher : North Holland
Page : 1052 pages
File Size : 43,6 Mb
Release : 1995-06-29
Category : Technology & Engineering
ISBN : 0444819754

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Structure and Dynamics of Membranes by R. Lipowsky,E. Sackmann Pdf

The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateral phase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes with polymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process of contact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned about the interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Author : Georg Pabst,Norbert Kučerka,Mu-Ping Nieh,John Katsaras
Publisher : CRC Press
Page : 482 pages
File Size : 42,5 Mb
Release : 2014-03-04
Category : Medical
ISBN : 9781466507098

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Liposomes, Lipid Bilayers and Model Membranes by Georg Pabst,Norbert Kučerka,Mu-Ping Nieh,John Katsaras Pdf

As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evolved from basic studies of the physicochemical properties of amphiphiles to their application in industry and medicine. Written by leading researchers in their fields, this book describes basic and applied research, and serves as a useful reference for both the novice and the expert. Part one covers a range of basic research topics, from theory and computational simulations to some of the most up-to-date experimental research. Topics discussed include soft matter physics of membranes, nonlamellar phases, extraction of molecules by amphiphiles, lipid models for membrane rafts, membrane dynamics, nanodiscs, microemulsions, active membranes, as well as interactions of bilayers with drugs or DNA to treat disease or for gene transfer, respectively. Part two of the book focuses on technological applications of amphiphiles, such as liposome-based nanoparticles for drug delivery, formulation of liposomes for prolonged in vivo circulation and functionalization for medical purposes, novel drug delivery systems for increased drug loading, and the use of tethered membranes for bio-sensing applications. Chapters also describe the use of liposomes in textile dyeing and how lipidic nanoparticles are used by the food industry.

Author : Tibor Hianik,Victor Ivanovich Passechnik
Publisher : Springer Science & Business Media
Page : 452 pages
File Size : 49,5 Mb
Release : 1995-08-31
Category : Science
ISBN : 9780792335511

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Bilayer Lipid Membranes. Structure and Mechanical Properties by Tibor Hianik,Victor Ivanovich Passechnik Pdf

In Bilayer Lipid Membranes. Structure and Mechanical Properties the authors use new methods of measurement, which they have themselves developed, to present an analysis of the relation between membrane structure and viscoelastic properties, in particular in the transversal direction. Hianik and Passechnik's approach is fundamentally different from the usual one, in that they analyze lipid bilayer dynamics during various modes of deformation, arriving at a new, `three-layer' model that accounts for the great heterogeneity of biomembranes. The macroscopic parameters of membranes have been measured using a wide variety of methods, leading to a discussion of the correlations between the parameters. There is also an extensive discussion of the dynamic changes in mechanical properties of lipid bilayers in the course of conformational transition of integral proteins. During the conformational changes of proteins, the structure of a bilayer undergoes a transition, reaching a new, stable membrane state. The book is the first to present a comprehensive analysis of long-distance interaction in lipid bilayers and of molecular mechanisms of mechanoreception. Audience: Scientists and graduate students working in biophysics, membranology, physiology, medicine, pharmacology, bioelectronics, electrochemistry, and colloid chemistry.

Author : Lukas K. Tamm
Publisher : John Wiley & Sons
Page : 470 pages
File Size : 54,8 Mb
Release : 2006-05-12
Category : Science
ISBN : 9783527606993

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Protein-Lipid Interactions by Lukas K. Tamm Pdf

In 17 contributions by leading research groups, this first comprehensive handbook in the field covers the interactions between proteins and lipids that make the fabric of biological membranes from every angle. It examines the relevant hermodynamic and structural issues from a basic science perspective, and goes on to discuss biochemical and cell biological processes. The book covers physical principles as well as mechanisms of membrane fusion and fission. Additionally, chapters on bilayer structure and protein-lipid interactions as well as on how proteins shape lipids and vice versa, membrane penetration by toxins, protein sorting, and allosteric regulation of signal transduction across membranes make this a valuable information source for researchers in academia and industry.

Author : Georg Pabst,Norbert Kucerka,Mu-Ping Nieh,John Katsaras
Publisher : CRC Press
Page : 470 pages
File Size : 42,8 Mb
Release : 2014-03-04
Category : Medical
ISBN : 9781466507111

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Liposomes, Lipid Bilayers and Model Membranes by Georg Pabst,Norbert Kucerka,Mu-Ping Nieh,John Katsaras Pdf

As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evo