Bilayer Lipid Membranes Structure And Mechanical Properties

Author : Tibor Hianik,Victor Ivanovich Passechnik
Publisher : Springer Science & Business Media
Page : 452 pages
File Size : 44,7 Mb
Release : 1995-08-31
Category : Science
ISBN : 9780792335511

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Bilayer Lipid Membranes. Structure and Mechanical Properties by Tibor Hianik,Victor Ivanovich Passechnik Pdf

In Bilayer Lipid Membranes. Structure and Mechanical Properties the authors use new methods of measurement, which they have themselves developed, to present an analysis of the relation between membrane structure and viscoelastic properties, in particular in the transversal direction. Hianik and Passechnik's approach is fundamentally different from the usual one, in that they analyze lipid bilayer dynamics during various modes of deformation, arriving at a new, `three-layer' model that accounts for the great heterogeneity of biomembranes. The macroscopic parameters of membranes have been measured using a wide variety of methods, leading to a discussion of the correlations between the parameters. There is also an extensive discussion of the dynamic changes in mechanical properties of lipid bilayers in the course of conformational transition of integral proteins. During the conformational changes of proteins, the structure of a bilayer undergoes a transition, reaching a new, stable membrane state. The book is the first to present a comprehensive analysis of long-distance interaction in lipid bilayers and of molecular mechanisms of mechanoreception. Audience: Scientists and graduate students working in biophysics, membranology, physiology, medicine, pharmacology, bioelectronics, electrochemistry, and colloid chemistry.

Author : E. Anibal Disalvo,Sidney A. Simon
Publisher : CRC Press
Page : 445 pages
File Size : 42,6 Mb
Release : 2017-12-14
Category : Science
ISBN : 9781351425384

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Permeability and Stability of Lipid Bilayers by E. Anibal Disalvo,Sidney A. Simon Pdf

This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 41,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : J. Katsaras,T. Gutberlet
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 54,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783662044964

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Lipid Bilayers by J. Katsaras,T. Gutberlet Pdf

Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.

Author : E. Anibal Disalvo
Publisher : Springer
Page : 284 pages
File Size : 46,6 Mb
Release : 2015-10-05
Category : Science
ISBN : 9783319190600

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Membrane Hydration by E. Anibal Disalvo Pdf

This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system. The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics. Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems. These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry, biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.

Author : E. Anibal Disalvo,Sidney A. Simon
Publisher : CRC Press
Page : 288 pages
File Size : 47,9 Mb
Release : 2017-12-14
Category : Science
ISBN : 9781351425391

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Permeability and Stability of Lipid Bilayers by E. Anibal Disalvo,Sidney A. Simon Pdf

This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.

Author : Fatma N. Kök,Ahu Arslan Yildiz,Fatih Inci
Publisher : Springer
Page : 306 pages
File Size : 43,6 Mb
Release : 2019-04-16
Category : Technology & Engineering
ISBN : 9783030115968

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Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization by Fatma N. Kök,Ahu Arslan Yildiz,Fatih Inci Pdf

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development. Provides fundamental knowledge on biomimetic lipid membranes; Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques; Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques; Describes the integration of biomimetic membranes with current top-notch tools and platforms; Examines applications in medicine, pharmaceutical industry, and environmental monitoring.

Author : Cyrus R. Safinya,Joachim Radler
Publisher : CRC Press
Page : 371 pages
File Size : 49,6 Mb
Release : 2021-09-14
Category : Medical
ISBN : 9781466555730

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Handbook of Lipid Membranes by Cyrus R. Safinya,Joachim Radler Pdf

This handbook provides a unique overview of lipid membrane fundamentals and applications. The fascinating world of lipids that harbor and govern so many biological functionalities are discussed within the context of membrane structures, interactions, and shape evolution. Beyond the fundamentals in lipid science, this handbook focuses on how scientists are building bioinspired biomimetic systems for applications in medicine, cosmetics, and nanotechnology. Key Features: Includes experimental and theoretical overviews on the role of lipids, with or without associated biomolecules, as structural components imparting distinct membrane shapes and intermembrane interactions Covers the mechanisms of lipid-membrane curvature, by peptide and protein binding, and the roles of signalling lipids and the cytoskeleton in plasma membrane shape evolution Covers advanced X-ray and force measurement techniques Discusses applications in biomedicine, cosmetics, and nanotechnology, including lipid vectors in nucleic acid, drug delivery in dermal applications, and lipid-based sensors and artificial biointerfaces Covers artificial membranes from block copolymers, synthetic copolypeptides, and recombinant proteins Includes an exciting section that explores the role of lipids in the origin of life in hydrothermal conditions This book is a highly informative companion for professionals in biophysics, biochemistry, physical chemistry, and material and pharmaceutical sciences and bioengineering.

Author : H.T. Tien †,A. Ottova-Leitmannova
Publisher : Elsevier
Page : 648 pages
File Size : 53,5 Mb
Release : 2000-01-11
Category : Technology & Engineering
ISBN : 0080536166

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Membrane Biophysics: As Viewed from Experimental Bilayer Lipid Membranes by H.T. Tien †,A. Ottova-Leitmannova Pdf

This book summarizes the current status of research on bilayer lipid membranes (planar lipid bilayers and spherical liposomes). In addition to describing the properties of lipid bilayers and examining biomembrane phenomena, the book has two other objectives. The first is to present practical methods for the formation and study of lipid bilayers with either aqueous or metal-lipid bilayer interfaces. The second aim is to treat planar lipid bilayers as a new type of interfacial adsorption phenomena. The first nine chapters cover properties of biomembranes, basic principles of membrane biophysics, transport, electrochemistry, physiology, bioenergetics, and photobiology. Chapter 10 presents the following topics: lipid bilayers in medicine, supported lipid bilayers as sensors, a short discussion of liposomes, and solar energy transduction via semiconductor septum photovoltaic cells based on natural photosynthesis.

Author : R. Lipowsky,E. Sackmann
Publisher : Elsevier
Page : 537 pages
File Size : 55,8 Mb
Release : 1995-06-15
Category : Technology & Engineering
ISBN : 9780080541914

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Structure and Dynamics of Membranes by R. Lipowsky,E. Sackmann Pdf

The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Author : M. Raafat El-Gewely
Publisher : Elsevier
Page : 422 pages
File Size : 43,8 Mb
Release : 2006-08-08
Category : Science
ISBN : 9780080465463

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Biotechnology Annual Review by M. Raafat El-Gewely Pdf

Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists’ knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, recent advances in all-protein chromophore technology- to topics that are focused on coencapsulation of hepatocytes and bone marrow cell. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training. Includes over 80 illustrations and photographs Discusses the recent developments in biodegradable synthetic polymers Offers a detailed discussion on emerging options in protein bioseparation

Author : A. Leitmannova Liu
Publisher : Elsevier
Page : 441 pages
File Size : 44,7 Mb
Release : 2011-08-09
Category : Mathematics
ISBN : 9780080466545

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Advances in Planar Lipid Bilayers and Liposomes by A. Leitmannova Liu Pdf

Volume 5 presents recent research on both planar lipid bilayers and liposomes based on their historic and experimental realization. Advances in Planar Lipid Bilayers and Liposomes, Volume 5, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group.Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is thefurther development of this interdisciplinary field worldwide. * Contributions from newcomers and established and experienced researchers* Exploring theoretically and experimentally the planar lipid bilayer systems and spherical liposomes* This volume is dedicated to mark the Bilayer Lipid Membranes 45th anniversary

Author : D.P. Nikolelis,Ulrich J. Krull,Joseph Wang,Marco Mascini
Publisher : Springer Science & Business Media
Page : 386 pages
File Size : 42,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9789401589734

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Biosensors for Direct Monitoring of Environmental Pollutants in Field by D.P. Nikolelis,Ulrich J. Krull,Joseph Wang,Marco Mascini Pdf

Biosensors offer clear and distinct advantages over standard analytical methods for the direct monitoring of environmental pollutants in the field, such as real-time detection with minimum sample preparation and handling. The present book highlights recent advantages that will be of great value to a range of scientists, researchers and students dealing with analytical and environmental chemistry and biosensor technology. It presents recent trends in analytical methodology for the determination of indoor and outdoor pollutants, advances in DNA, biological and recognition-based sensors, examples of biosensors for use in field and water analysis, biosensors based on non-aqueous systems, and recent advances in the miniaturisation and micromachining of biosensors.

Author : Philip N. Bartlett
Publisher : John Wiley & Sons
Page : 494 pages
File Size : 41,7 Mb
Release : 2008-05-27
Category : Science
ISBN : 9780470753835

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Bioelectrochemistry by Philip N. Bartlett Pdf

Bioelectrochemistry: Fundamentals, Experimental Techniques and Application, covers the fundamental aspects of the chemistry, physics and biology which underlie this subject area. It describes some of the different experimental techniques that can be used to study bioelectrochemical problems and it describes various applications of biolelectrochemisty including amperometric biosensors, immunoassays, electrochemistry of DNA, biofuel cells, whole cell biosensors, in vivo applications and bioelectrosynthesis. By bringing together these different aspects, this work provides a unique source of information in this area, approaching the subject from a cross-disciplinary viewpoint.

Author : Igor Lacković,Darko Vasic
Publisher : Springer
Page : 1035 pages
File Size : 46,9 Mb
Release : 2014-09-02
Category : Technology & Engineering
ISBN : 9783319111285

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6th European Conference of the International Federation for Medical and Biological Engineering by Igor Lacković,Darko Vasic Pdf

This volume presents the Proceedings of the 6th European Conference of the International Federation for Medical and Biological Engineering (MBEC2014), held in Dubrovnik September 7 – 11, 2014. The general theme of MBEC 2014 is "Towards new horizons in biomedical engineering" The scientific discussions in these conference proceedings include the following themes: - Biomedical Signal Processing - Biomedical Imaging and Image Processing - Biosensors and Bioinstrumentation - Bio-Micro/Nano Technologies - Biomaterials - Biomechanics, Robotics and Minimally Invasive Surgery - Cardiovascular, Respiratory and Endocrine Systems Engineering - Neural and Rehabilitation Engineering - Molecular, Cellular and Tissue Engineering - Bioinformatics and Computational Biology - Clinical Engineering and Health Technology Assessment - Health Informatics, E-Health and Telemedicine - Biomedical Engineering Education