Handbook Of Research On Medicinal Chemistry

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The Handbook of Medicinal Chemistry

Simon E Ward,Andrew Davis
The Handbook of Medicinal Chemistry Book PDF

Author : Simon E Ward,Andrew Davis
Publisher : Royal Society of Chemistry
Page : 1051 pages
File Size : 47,8 Mb
Release : 2023-02-03
Category : Medical
ISBN : 9781839165887

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The Handbook of Medicinal Chemistry by Simon E Ward,Andrew Davis Pdf

Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.

Handbook of Research on Medicinal Chemistry

Debarshi Kar Mahapatra,Sanjay Kumar Bharti
Handbook of Research on Medicinal Chemistry Book PDF

Author : Debarshi Kar Mahapatra,Sanjay Kumar Bharti
Publisher : Taylor & Francis
Page : 648 pages
File Size : 55,8 Mb
Release : 2017-11-20
Category : Medical
ISBN : 9781771885454

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Handbook of Research on Medicinal Chemistry by Debarshi Kar Mahapatra,Sanjay Kumar Bharti Pdf

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include: drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.

The Handbook of Medicinal Chemistry

Andrew Davis,Simon E Ward
The Handbook of Medicinal Chemistry Book PDF

Author : Andrew Davis,Simon E Ward
Publisher : Royal Society of Chemistry
Page : 753 pages
File Size : 40,5 Mb
Release : 2015-07-07
Category : Science
ISBN : 9781782621836

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The Handbook of Medicinal Chemistry by Andrew Davis,Simon E Ward Pdf

Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.

The Practice of Medicinal Chemistry

Camille Georges Wermuth
The Practice of Medicinal Chemistry Book PDF

Author : Camille Georges Wermuth
Publisher : Elsevier
Page : 736 pages
File Size : 40,7 Mb
Release : 2003-06-11
Category : Science
ISBN : 9780080497778

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The Practice of Medicinal Chemistry by Camille Georges Wermuth Pdf

The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. * The only book available dealing with the practical aspects of medicinal chemistry * Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production * Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry

Medicinal Chemistry Handbook

Thomas Haldane
Medicinal Chemistry Handbook Book PDF

Author : Thomas Haldane
Publisher : Unknown
Page : 0 pages
File Size : 47,7 Mb
Release : 2015-01-21
Category : Science
ISBN : 1632383195

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Medicinal Chemistry Handbook by Thomas Haldane Pdf

This book contains researches based on medicinal chemistry and its sub-disciplines. The aim of this book is to provide an overview of recent issues and some significant advances in medicinal science. However, the major emphasis is on theoretical and experimental theories of modern drug designing, in order to help researchers, chemists, pharmaceutical specialists and chemical engineers in their future projects. This book will serve as a resource guide in the field of medicinal chemistry and facilitate the progress of this field.

Handbook of Research on Medicinal Chemistry

Debarshi Kar Mahapatra,Sanjay Kumar Bharti
Handbook of Research on Medicinal Chemistry Book PDF

Author : Debarshi Kar Mahapatra,Sanjay Kumar Bharti
Publisher : Taylor & Francis
Page : 628 pages
File Size : 51,8 Mb
Release : 2017-11-20
Category : Medical
ISBN : 9781351800235

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Handbook of Research on Medicinal Chemistry by Debarshi Kar Mahapatra,Sanjay Kumar Bharti Pdf

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include: drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.

The Practice of Medicinal Chemistry

Camille Georges Wermuth
The Practice of Medicinal Chemistry Book PDF

Author : Camille Georges Wermuth
Publisher : Academic Press
Page : 982 pages
File Size : 43,9 Mb
Release : 2011-05-02
Category : Medical
ISBN : 9780080568775

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The Practice of Medicinal Chemistry by Camille Georges Wermuth Pdf

The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry. NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics

Medicinal Chemistry

Gareth Thomas
Medicinal Chemistry Book PDF

Author : Gareth Thomas
Publisher : John Wiley & Sons
Page : 660 pages
File Size : 41,6 Mb
Release : 2011-09-20
Category : Science
ISBN : 9781119965428

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Medicinal Chemistry by Gareth Thomas Pdf

Medicinal Chemistry: An Introduction, Second Edition provides a comprehensive, balanced introduction to this evolving and multidisciplinary area of research. Building on the success of the First Edition, this edition has been completely revised and updated to include the latest developments in the field. Written in an accessible style, Medicinal Chemistry: An Introduction, Second Edition carefully explains fundamental principles, assuming little in the way of prior knowledge. The book focuses on the chemical principles used for drug discovery and design covering physiology and biology where relevant. It opens with a broad overview of the subject with subsequent chapters examining topics in greater depth. From the reviews of the First Edition: "It contains a wealth of information in a compact form" ANGEWANDTE CHEMIE, INTERNATIONAL EDITION "Medicinal Chemistry is certainly a text I would chose to teach from for undergraduates. It fills a unique niche in the market place." PHYSICAL SCIENCES AND EDUCATIONAL REVIEWS

Fundamentals of Medicinal Chemistry

Gareth Thomas
Fundamentals of Medicinal Chemistry Book PDF

Author : Gareth Thomas
Publisher : John Wiley & Sons
Page : 302 pages
File Size : 44,7 Mb
Release : 2004-04-20
Category : Science
ISBN : 9780470871690

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Fundamentals of Medicinal Chemistry by Gareth Thomas Pdf

Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product. The text assumes little in the way of prior biological knowledge. relevant biology is included through biological topics, examples and the Appendices. Incorporates summary sections, examples, applications and problems Each chapter contains an additional summary section and solutions to the questions are provided at the end of the text Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences.

Medicinal Chemistry for Practitioners

Jie Jack Li
Medicinal Chemistry for Practitioners Book PDF

Author : Jie Jack Li
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 49,5 Mb
Release : 2020-06-29
Category : Medical
ISBN : 9781119607304

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Medicinal Chemistry for Practitioners by Jie Jack Li Pdf

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.

The Practice of Medicinal Chemistry

Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan
The Practice of Medicinal Chemistry Book PDF

Author : Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan
Publisher : Elsevier
Page : 903 pages
File Size : 55,9 Mb
Release : 2015-07-01
Category : Science
ISBN : 9780124172135

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The Practice of Medicinal Chemistry by Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan Pdf

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com

Handbook of Molecular Descriptors

Roberto Todeschini,Viviana Consonni
Handbook of Molecular Descriptors Book PDF

Author : Roberto Todeschini,Viviana Consonni
Publisher : John Wiley & Sons
Page : 688 pages
File Size : 45,9 Mb
Release : 2008-07-11
Category : Science
ISBN : 9783527613113

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Handbook of Molecular Descriptors by Roberto Todeschini,Viviana Consonni Pdf

Quantitative studies on structure-activity and structure-property relationships are powerful tools in directed drug research. In recent years, various strategies have been developed to characterize and classify structural patterns by means of molecular descriptors. It has become possible not only to assess diversities or similarities of structure databases, but molecular descriptors also facilitate the identification of potential bioactive molecules from the rapidly increasing number of compound libraries. They even allow for a controlled de-novo design of new lead structures. This is the most comprehensive collection of molecular descriptors and presents a detailed review from the origins of this research field up to present day. This practically oriented reference book gives a thorough overview of the different molecular descriptors representations and their corresponding molecular descriptors. All descriptors are listed with their definition, symbols and labels, formulas, some numerical examples, data and molecular graphs, while numerous figures and tables aid comprehension of the definitions. Cross-references throughout, a list of acronyms and notations allow easy access to the information needed to solve a specific research problem. Examples of descriptor calculations along with tables of descriptor values for a set of selected reference compounds and an up-to-date reference list add to the practical value of the book, making it an invaluable guide for all those dealing with bioactive molecules as well as for researchers.

Medicinal Chemistry

A.K. Ganguly,Sesha Sridevi Alluri
Medicinal Chemistry Book PDF

Author : A.K. Ganguly,Sesha Sridevi Alluri
Publisher : CRC Press
Page : 118 pages
File Size : 53,8 Mb
Release : 2021-09-12
Category : Medical
ISBN : 9781000437218

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Medicinal Chemistry by A.K. Ganguly,Sesha Sridevi Alluri Pdf

Medicinal Chemistry: A Look at How Drugs Are Discovered is written for those who are interested in learning how drugs are discovered. Compared to other books on the market, this text takes a different approach by presenting the subject on chemical reaction mechanism terms, which ideally makes the subject matter more interesting and easier to comprehend. The authors describe the drug discovery process, from advancing an initial lead to the approval process, and include drug discovery sources. Additional features: Explains medicinal chemistry on chemical mechanism terms, allowing for a more interesting and easier to comprehend text Includes valuable insights toward the various pathways taken at pharmaceutical industries in drug discoveries Improved by including questions raised and suggestions made from students in the authors’ medicinal chemistry classes This book will benefit both upper level undergraduates and graduates studying in the fields of medicinal chemistry and drug discovery, as well as scientists working in the pharmaceutical industry.

Medicinal Chemistry

C. R. Ganellin,Stanley M. Roberts
Medicinal Chemistry Book PDF

Author : C. R. Ganellin,Stanley M. Roberts
Publisher : Academic Press
Page : 332 pages
File Size : 52,9 Mb
Release : 1993-02-26
Category : Medical
ISBN : UOM:39015029520718

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Medicinal Chemistry by C. R. Ganellin,Stanley M. Roberts Pdf

This new edition aims to introduce students to the mechanisms of action of drugs and the approaches adopted in designing new drugs. It also contains chapters on individual successful drugs written by their discoverers or developers, tracing their history to the present day.

Handbook of Drug Screening

Ramakrishna Seethala,Prabhavathi Fernandes
Handbook of Drug Screening Book PDF

Author : Ramakrishna Seethala,Prabhavathi Fernandes
Publisher : CRC Press
Page : 619 pages
File Size : 52,9 Mb
Release : 2001-07-24
Category : Medical
ISBN : 9780824741440

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Handbook of Drug Screening by Ramakrishna Seethala,Prabhavathi Fernandes Pdf

A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.