Handbook Of Translational Medicine

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Handbook of Translational Medicine

Kathlyn Rafferty
Handbook of Translational Medicine Book PDF

Author : Kathlyn Rafferty
Publisher : Foster Academics
Page : 0 pages
File Size : 54,9 Mb
Release : 2023-09-19
Category : Medical
ISBN : 164646625X

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Handbook of Translational Medicine by Kathlyn Rafferty Pdf

Translational medicine is an interdisciplinary branch of the biomedical field that aims to improve human health and longevity by determining the relevance of novel discoveries to human disease in the biological sciences. It is also referred to as translational science. This area of research is supported by three main pillars, namely, benchside, bedside and community. Translational medicine integrates disciplines, resources, expertise, and techniques within these pillars to promote enhancements in prevention, diagnosis, and therapies. It focuses on enhancing clinical medicine by incorporating the latest developments in research, reducing the gap between upcoming knowledge and its clinical application. Translational medicine plays an important role in shortening the duration of clinical trials and providing cost-effective solutions for healthcare delivery. This book provides comprehensive insights into the fundamentals of translational medicine. It is an essential guide for the graduate and postgraduate students, professionals and researchers engaged in this field.

Handbook of translational medicine

Josep M. Llovet
Handbook of translational medicine Book PDF

Author : Josep M. Llovet
Publisher : Edicions Universitat Barcelona
Page : 245 pages
File Size : 45,9 Mb
Release : 2016-10-05
Category : Medical
ISBN : 9788447540303

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Handbook of translational medicine by Josep M. Llovet Pdf

This handbook aims to capture the basic concepts of translational medicine, understood as a branch of the biomedical field that translates discoveries into the clinical setting. This discipline is currently closing the gap between basic science and clinical research. The book is intended to be straightforward, easy-to-read, intelligible and practical. It describes the basic principles of translational medicine, including major advances in genomics, new technologies, the processing of big data and biobanks. Regarding the biological foundations of translational medicine, we address concepts related to the molecular basis of cancer, inflammation, angiogenesis, stem cells and experimental models. More specifically on translational medicine, we present discoveries and breakthroughs in oncology, neuroscience, metabolic and systemic diseases, and public health. Finally, we have specific sections focused on clinical trials and biomarkers in the genomic era, advances in imaging techniques and entrepreneurship and innovation. Our purpose is to offer a manageable text to guide graduate and post-graduate students, professionals and researchers in biomedicine through the major technologies and advances that have occurred in the translational field. It is also intended to aid residents, fellows and physician-scientists working in hospitals and academic institutions.

ESMO Handbook on Principles of Translational Research

Håkan Mellstedt,Dirk Schrijvers,Dimitrios Bafaloukos,Richard Griel
ESMO Handbook on Principles of Translational Research Book PDF

Author : Håkan Mellstedt,Dirk Schrijvers,Dimitrios Bafaloukos,Richard Griel
Publisher : CRC Press
Page : 192 pages
File Size : 53,9 Mb
Release : 2007-05-21
Category : Medical
ISBN : 9780203092422

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ESMO Handbook on Principles of Translational Research by Håkan Mellstedt,Dirk Schrijvers,Dimitrios Bafaloukos,Richard Griel Pdf

Using state-of-the-art and evidence-based literature references and reviews, the authors present an overview of translational research that is both reliable and easily understood. The book begins with principles of normal cell biology and normal immunology. It examines tumor biology and basic tumor immunology. It then discusses limitless replicativ

Translational Medicine: Tools And Techniques

Aamir Shahzad
Translational Medicine Tools And Techniques Book PDF

Author : Aamir Shahzad
Publisher : Academic Press
Page : 196 pages
File Size : 48,5 Mb
Release : 2015-11-24
Category : Medical
ISBN : 9780128034941

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Translational Medicine: Tools And Techniques by Aamir Shahzad Pdf

Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine techniques and tools in various settings, readers will be guided through implementation strategies relevant to their own needs and institutions. The book also addresses regulatory processes in USA, EU, Japan and China. By providing details on omics sciences techniques, biomarkers, data mining and management approaches, case reports from industry, and tools to assess the value of different technologies and techniques, this book is the first to provide a user-friendly go-to guide for key opinion leaders (KOLs), industry administrators, faculty members, clinicians, researchers, and students interested in translational medicine. Includes detailed and standardized information about the techniques and tools used in translational medicine Provides specific industry case scenarios Explains how to use translational medicine tools and techniques to plan and improve infrastructures and capabilities while reducing cost and optimizing resources

Principles of Translational Science in Medicine

Martin Wehling
Principles of Translational Science in Medicine Book PDF

Author : Martin Wehling
Publisher : Academic Press
Page : 495 pages
File Size : 50,5 Mb
Release : 2021-07-15
Category : Science
ISBN : 9780323999625

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Principles of Translational Science in Medicine by Martin Wehling Pdf

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Clinical and Translational Science

David Robertson,Gordon H. Williams
Clinical and Translational Science Book PDF

Author : David Robertson,Gordon H. Williams
Publisher : Academic Press
Page : 812 pages
File Size : 52,8 Mb
Release : 2016-11-25
Category : Science
ISBN : 9780128021118

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Clinical and Translational Science by David Robertson,Gordon H. Williams Pdf

Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Translational Medicine and Drug Discovery

Bruce H. Littman,Rajesh Krishna
Translational Medicine and Drug Discovery Book PDF

Author : Bruce H. Littman,Rajesh Krishna
Publisher : Cambridge University Press
Page : 385 pages
File Size : 41,9 Mb
Release : 2011-01-31
Category : Medical
ISBN : 9781139498722

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Translational Medicine and Drug Discovery by Bruce H. Littman,Rajesh Krishna Pdf

This book focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry. It is essential for anyone interested in translational medicine from a variety of backgrounds: university institutes, medical schools, pharmaceutical companies and drug development researchers and decision-makers.

Cell Biology and Translational Medicine, Volume 2

Kursad Turksen
Cell Biology and Translational Medicine Volume 2 Book PDF

Author : Kursad Turksen
Publisher : Springer
Page : 155 pages
File Size : 55,6 Mb
Release : 2018-11-28
Category : Science
ISBN : 9783030041700

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Cell Biology and Translational Medicine, Volume 2 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This online first book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the second volume of a continuing series.

ESMO Handbook of Principles of Translational Research

Håkan Mellstedt
ESMO Handbook of Principles of Translational Research Book PDF

Author : Håkan Mellstedt
Publisher : Informa Medical
Page : 192 pages
File Size : 55,6 Mb
Release : 2014-05-14
Category : Cytology
ISBN : 143562615X

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ESMO Handbook of Principles of Translational Research by Håkan Mellstedt Pdf

Medical oncologists and other healthcare professionals in the field of oncology will welcome this concise guide on the new and rapidly evolving field of cellular oncology and targeted therapies. This handbook presents the principles of cell biology and the role of the immune system; the etiology of carcinogenesis; differenct cellular pathways, and their implications for drug development in oncology. Using state-of-the-art ecidence-based literature references and reviews, with illustrations as necessary, the authors present on overvieew that is both reliable and easily understood.

Cell Biology and Translational Medicine, Volume 13

Kursad Turksen
Cell Biology and Translational Medicine Volume 13 Book PDF

Author : Kursad Turksen
Publisher : Springer Nature
Page : 195 pages
File Size : 47,7 Mb
Release : 2021-08-26
Category : Science
ISBN : 9783030790585

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Cell Biology and Translational Medicine, Volume 13 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the thirteenth volume of a continuing series.

Translational Medicine

Dennis Cosmatos,Shein-Chung Chow
Translational Medicine Book PDF

Author : Dennis Cosmatos,Shein-Chung Chow
Publisher : CRC Press
Page : 224 pages
File Size : 48,7 Mb
Release : 2019-08-30
Category : Electronic
ISBN : 0367386178

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Translational Medicine by Dennis Cosmatos,Shein-Chung Chow Pdf

Examines Critical Decisions for Transitioning Lab Science to a Clinical Setting The development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result, translational medicine (TM) is becoming increasingly important in the healthcare industry - a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery, through pre-clinical testing, early clinical trials, and late confirmatory studies that lead to regulatory approval of drug release to patients. Translational Medicine: Strategies and Statistical Methods suggests a process for transitioning from the initial lab discovery to the patient's bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research. Documents Alternative Research Approaches for Faster and More Accurate Data Judgment Calls Elaborating on how to introduce TM into clinical studies, this authoritative work presents a keen approach to building, executing, and validating statistical models that consider data from various phases of development. It also delineates a truly translational example to help bolster understanding of discussed concepts. This comprehensive guide effectively demonstrates how to overcome obstacles related to successful TM practice. It contains invaluable information for pharmaceutical scientists, research executives, clinicians, and biostatisticians looking to expedite successful implementation of this important process.

Cell Biology and Translational Medicine, Volume 7

Kursad Turksen
Cell Biology and Translational Medicine Volume 7 Book PDF

Author : Kursad Turksen
Publisher : Springer Nature
Page : 158 pages
File Size : 55,8 Mb
Release : 2020-02-03
Category : Science
ISBN : 9783030378455

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Cell Biology and Translational Medicine, Volume 7 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series. Chapter “Application of iPSC to Modelling of Respiratory Diseases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Cell Biology and Translational Medicine, Volume 3

Kursad Turksen
Cell Biology and Translational Medicine Volume 3 Book PDF

Author : Kursad Turksen
Publisher : Springer
Page : 205 pages
File Size : 53,5 Mb
Release : 2018-11-28
Category : Science
ISBN : 9783030041854

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Cell Biology and Translational Medicine, Volume 3 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the third volume of a continuing series.

The Routledge Handbook of Translation and Health

Şebnem Susam-Saraeva,Eva Spišiaková
The Routledge Handbook of Translation and Health Book PDF

Author : Şebnem Susam-Saraeva,Eva Spišiaková
Publisher : Taylor & Francis
Page : 491 pages
File Size : 54,9 Mb
Release : 2021-05-09
Category : Language Arts & Disciplines
ISBN : 9781000382709

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The Routledge Handbook of Translation and Health by Şebnem Susam-Saraeva,Eva Spišiaková Pdf

The Routledge Handbook of Translation and Health provides a bridge between translation studies and the burgeoning field of health humanities, which seeks novel ways of understanding health and illness. As discourses around health and illness are dependent on languages for their transmission, impact, spread, acceptance and rejection in local settings, translation studies offers a wealth of data, theoretical approaches and methods for studying health and illness globally. Translation and health intersect in a multitude of settings, historical moments, genres, media and users. This volume brings together topics ranging from interpreting in healthcare settings to translation within medical sciences, from historical and contemporary travels of medicine through translation to areas such as global epidemics, disaster situations, interpreting for children, mental health, women’s health, disability, maternal health, queer feminisms and sexual health, and nutrition. Contributors come from a wide range of disciplines, not only from various branches of translation and interpreting studies, but also from disciplines such as psychotherapy, informatics, health communication, interdisciplinary health science and classical Islamic studies. Divided into four sections and each contribution written by leading international authorities, this timely Handbook is an indispensable resource for all students and researchers of translation and health within translation and interpreting studies, as well as medical and health humanities. Introduction and Chapter 18 of this book are freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Biomedical Translational Research

R.C. Sobti,Naranjan S. Dhalla
Biomedical Translational Research Book PDF

Author : R.C. Sobti,Naranjan S. Dhalla
Publisher : Springer Nature
Page : 597 pages
File Size : 43,7 Mb
Release : 2022-07-28
Category : Medical
ISBN : 9789811692321

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Biomedical Translational Research by R.C. Sobti,Naranjan S. Dhalla Pdf

This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.