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Handbook on Metalloproteins by Ivano Bertini,Astrid Sigel Pdf
This Handbook on Metalloproteins focuses on the available structural information of proteins and their metal ion coordination spheres. It centers on the metal ions indispensable for life but also considers metal ions used as substitution probes in studies of metalloproteins. Emphasizing the structure-function relationship, the book covers the commo
Handbook of Metalloproteins, Handbook of Metalloproteins by Albrecht Messerschmidt Pdf
The first two volumes of the "Handbook of Metalloproteins", published in 2001, focused on a number of metals, including iron, nickel, manganese, cobalt, copper and vanadium. Now we are delighted to present volume three which extends the wealth of knowledge and focuses on proteins found in the redox-inactive ions of zinc and calcium. (Midwest).
Handbook of Metalloproteins, 3 volume set by Albrecht Messerschmidt Pdf
The first two volumes of the "Handbook of Metalloproteins", published in 2001, focused on a number of metals, including iron, nickel, manganese, cobalt, copper and vanadium. Now we are delighted to present volume three which extends the wealth of knowledge and focuses on proteins found in the redox-inactive ions of zinc and calcium. * Colour illustrations throughout * 3D structures of modified metalloproteins for easier understanding of functions * International expert contributors The amazing new set will prove to be an essential reference providing comprehensive understanding and focused coverage of metalloproteins. "it is a pleasure to use ...this excellent, authoritative, and valuable text...I regard this work as essential for library purchase..." (Natural Products Report, Vol.19, No.4, 2002) "highly recommended as a resource for bioinorganic chemistry. It will have lasting value for researchers in the field" (The Alchemist - Chemweb, 2002)
Handbook on Metalloproteins by Ivano Bertini,Astrid Sigel Pdf
This Handbook on Metalloproteins focuses on the available structural information of proteins and their metal ion coordination spheres. It centers on the metal ions indispensable for life but also considers metal ions used as substitution probes in studies of metalloproteins. Emphasizing the structure-function relationship, the book covers the common and distinct characterstics of metallo- enzymes, proteins, and amino acids bonded to copper, zinc, iron, and more.
Author : Michael K. Johnson,Robert A. Scott Publisher : John Wiley & Sons Page : 424 pages File Size : 43,7 Mb Release : 2017-08-30 Category : Science ISBN : 9781119159841
Metalloprotein Active Site Assembly by Michael K. Johnson,Robert A. Scott Pdf
Summarizes the essential biosynthetic pathways for assembly of metal cofactor sites in functional metalloproteins Metalloprotein Active Site Assembly focuses on the processes that have evolved to orchestrate the assembly of metal cofactor sites in functional metalloproteins. It goes beyond the simple incorporation of single metal ions in a protein framework, and includes metal cluster assembly, metal-cofactor biosynthesis and insertion, and metal-based post-translational modifications of the protein environments that are necessary for function. Several examples of each of these areas have now been identified and studied; the current volume provides the current state-of-the-art understanding of the processes involved. An excellent companion to the earlier book in this series Metals in Cells—which discussed both the positive and negative effects of cellular interactions with metals—this comprehensive book provides a diverse sampling of what is known about metalloprotein active site assembly processes. It covers all major biological transition metal components (Mn, Fe, Co, Ni, Mo), as well as the other inorganic components, metal-binding organic cofactors (e.g., heme, siroheme, cobalamin, molybdopterin), and post-translationally modified metal binding sites that make up the patchwork of evolved biological catalytic sites. The book compares and contrasts the biosynthetic assembly of active sites involving all biological metals. This has never been done before since it is a relatively new, fast-developing area of research. Metalloprotein Active Site Assembly is an ideal text for practitioners of inorganic biochemistry who are studying the biosynthetic pathways and gene clusters involved in active site assembly, and for inorganic chemists who want to apply the concepts learned to potential synthetic pathways to active site mimics.
Handbook of Metalloproteins by Albrecht Messerschmidt Pdf
Researching the structure and function of metalloproteins is one of the biggest challenges in modern biological chemistry - and several Nobel Prizes have been awarded to research in the field, including to the Co-Editor Robert Huber in 1988. This 5-Volume Set gives a representative presentation of the key enzymes [= Metalloproteins and reflect the success of the current ongoing research and includes coverage of 234 Metalloproteins. The set comprises of Volumes 1 & 2 published in 2001, Volume 3 published in 2004 and Volumes 4 & 5 published in February 2011. Praise for this publication includes: "It is a pleasure just to read this handsome and carefully produced work..." From volumes 1 & 2, Angewandte Chemie , vol. 41, 2002) "it is a pleasure to use... this excellent, authoritative, and valuable text...I regard this work as essential for library purchase..." Natural Products Report, Vol.19, No.4, 2002 "highly recommended as a resource for bioinorganic chemistry. It will have lasting value for researchers in the field" The Alchemist - Chemweb, 2002 Also available online via http://onlinelibrary.wiley.com/book/10.1002/0470028637
Annotation As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an invaluable source of current methods and applications. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an in valuable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Chemistry of Metalloproteins by Joseph J. Stephanos,Anthony W. Addison Pdf
Addresses the full gamut of questions in metalloprotein science Formatted as a question-and-answer guide, this book examines all major families of metal binding proteins, presenting our most current understanding of their structural, physicochemical, and functional properties. Moreover, it introduces new and emerging medical applications of metalloproteins. Readers will discover both the underlying chemistry and biology of this important area of research in bioinorganic chemistry. Chemistry of Metalloproteins features a building block approach that enables readers to master the basics and then advance to more sophisticated topics. The book begins with a general introduction to bioinorganic chemistry and metalloproteins. Next, it covers: Alkali and alkaline earth cations Metalloenzymes Copper proteins Iron proteins Vitamin B12 Chlorophyll Chapters are richly illustrated to help readers fully grasp all the chemical concepts that govern the biological action of metalloproteins. In addition, each chapter ends with a list of suggested original research articles and reviews for further investigation of individual topics. Presenting our most current understanding of metalloproteins, Chemistry of Metalloproteins is recommended for students and researchers in coordination chemistry, biology, and medicine. Each volume of the Wiley Series in Protein and Peptide Science addresses a specific facet of the field, reviewing the latest findings and presenting a broad range of perspectives. The volumes in this series constitute essential reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, and physiologists as well as researchers in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.
Metal-Carbon Bonds in Enzymes and Cofactors by Astrid Sigel,Helmut Sigel,Roland K.O. Sigel Pdf
The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.
Extremophiles Handbook by Koki Horikoshi,Garabed Antranikian,Alan T. Bull,Frank T. Robb,Karl O. Stetter Pdf
The Extremophiles Handbook brings together the rapidly growing and often scattered information on microbial life in the whole range of extreme environments. This book will be a useful reference for finding clues to the origin of life and for exploring the biotechnology potential of these fascinating organisms.
Biological Inorganic Chemistry by Ivano Bertini Pdf
Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.
Metal Ions in Biological Systems by Helmut Sigel Pdf
The Metal Ions in Biological Systems series is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Written by 36 internationally recognized experts and enriched with nearly 200 illustrations, Volume 40 highlights fast moving research on lanthanides and their interrelations with biosystems and emphasizes their recent impact in biochemical and biological studies, and in medicine.
