Hands On Data Science For Biologists Using Python

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Hands on Data Science for Biologists Using Python

Author : Yasha Hasija,Rajkumar Chakraborty
Publisher : CRC Press
Page : 299 pages
File Size : 45,7 Mb
Release : 2021-04-08
Category : Computers
ISBN : 9781000345483

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Hands on Data Science for Biologists Using Python by Yasha Hasija,Rajkumar Chakraborty Pdf

Hands-on Data Science for Biologists using Python has been conceptualized to address the massive data handling needs of modern-day biologists. With the advent of high throughput technologies and consequent availability of omics data, biological science has become a data-intensive field. This hands-on textbook has been written with the inception of easing data analysis by providing an interactive, problem-based instructional approach in Python programming language. The book starts with an introduction to Python and steadily delves into scrupulous techniques of data handling, preprocessing, and visualization. The book concludes with machine learning algorithms and their applications in biological data science. Each topic has an intuitive explanation of concepts and is accompanied with biological examples. Features of this book: The book contains standard templates for data analysis using Python, suitable for beginners as well as advanced learners. This book shows working implementations of data handling and machine learning algorithms using real-life biological datasets and problems, such as gene expression analysis; disease prediction; image recognition; SNP association with phenotypes and diseases. Considering the importance of visualization for data interpretation, especially in biological systems, there is a dedicated chapter for the ease of data visualization and plotting. Every chapter is designed to be interactive and is accompanied with Jupyter notebook to prompt readers to practice in their local systems. Other avant-garde component of the book is the inclusion of a machine learning project, wherein various machine learning algorithms are applied for the identification of genes associated with age-related disorders. A systematic understanding of data analysis steps has always been an important element for biological research. This book is a readily accessible resource that can be used as a handbook for data analysis, as well as a platter of standard code templates for building models.

Hands on Data Science for Biologists Using Python

Author : Yasha Hasija,Rajkumar Chakraborty
Publisher : CRC Press
Page : 243 pages
File Size : 46,7 Mb
Release : 2021-04-09
Category : Science
ISBN : 9781000345506

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Hands on Data Science for Biologists Using Python by Yasha Hasija,Rajkumar Chakraborty Pdf

Hands-on Data Science for Biologists using Python has been conceptualized to address the massive data handling needs of modern-day biologists. With the advent of high throughput technologies and consequent availability of omics data, biological science has become a data-intensive field. This hands-on textbook has been written with the inception of easing data analysis by providing an interactive, problem-based instructional approach in Python programming language. The book starts with an introduction to Python and steadily delves into scrupulous techniques of data handling, preprocessing, and visualization. The book concludes with machine learning algorithms and their applications in biological data science. Each topic has an intuitive explanation of concepts and is accompanied with biological examples. Features of this book: The book contains standard templates for data analysis using Python, suitable for beginners as well as advanced learners. This book shows working implementations of data handling and machine learning algorithms using real-life biological datasets and problems, such as gene expression analysis; disease prediction; image recognition; SNP association with phenotypes and diseases. Considering the importance of visualization for data interpretation, especially in biological systems, there is a dedicated chapter for the ease of data visualization and plotting. Every chapter is designed to be interactive and is accompanied with Jupyter notebook to prompt readers to practice in their local systems. Other avant-garde component of the book is the inclusion of a machine learning project, wherein various machine learning algorithms are applied for the identification of genes associated with age-related disorders. A systematic understanding of data analysis steps has always been an important element for biological research. This book is a readily accessible resource that can be used as a handbook for data analysis, as well as a platter of standard code templates for building models.

Hands-On Data Science and Python Machine Learning

Author : Frank Kane
Publisher : Packt Publishing Ltd
Page : 420 pages
File Size : 46,9 Mb
Release : 2017-07-31
Category : Computers
ISBN : 9781787280229

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Hands-On Data Science and Python Machine Learning by Frank Kane Pdf

This book covers the fundamentals of machine learning with Python in a concise and dynamic manner. It covers data mining and large-scale machine learning using Apache Spark. About This Book Take your first steps in the world of data science by understanding the tools and techniques of data analysis Train efficient Machine Learning models in Python using the supervised and unsupervised learning methods Learn how to use Apache Spark for processing Big Data efficiently Who This Book Is For If you are a budding data scientist or a data analyst who wants to analyze and gain actionable insights from data using Python, this book is for you. Programmers with some experience in Python who want to enter the lucrative world of Data Science will also find this book to be very useful, but you don't need to be an expert Python coder or mathematician to get the most from this book. What You Will Learn Learn how to clean your data and ready it for analysis Implement the popular clustering and regression methods in Python Train efficient machine learning models using decision trees and random forests Visualize the results of your analysis using Python's Matplotlib library Use Apache Spark's MLlib package to perform machine learning on large datasets In Detail Join Frank Kane, who worked on Amazon and IMDb's machine learning algorithms, as he guides you on your first steps into the world of data science. Hands-On Data Science and Python Machine Learning gives you the tools that you need to understand and explore the core topics in the field, and the confidence and practice to build and analyze your own machine learning models. With the help of interesting and easy-to-follow practical examples, Frank Kane explains potentially complex topics such as Bayesian methods and K-means clustering in a way that anybody can understand them. Based on Frank's successful data science course, Hands-On Data Science and Python Machine Learning empowers you to conduct data analysis and perform efficient machine learning using Python. Let Frank help you unearth the value in your data using the various data mining and data analysis techniques available in Python, and to develop efficient predictive models to predict future results. You will also learn how to perform large-scale machine learning on Big Data using Apache Spark. The book covers preparing your data for analysis, training machine learning models, and visualizing the final data analysis. Style and approach This comprehensive book is a perfect blend of theory and hands-on code examples in Python which can be used for your reference at any time.

Practical Data Science with Python

Author : Nathan George
Publisher : Packt Publishing Ltd
Page : 621 pages
File Size : 54,7 Mb
Release : 2021-09-30
Category : Computers
ISBN : 9781801076654

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Practical Data Science with Python by Nathan George Pdf

Learn to effectively manage data and execute data science projects from start to finish using Python Key FeaturesUnderstand and utilize data science tools in Python, such as specialized machine learning algorithms and statistical modelingBuild a strong data science foundation with the best data science tools available in PythonAdd value to yourself, your organization, and society by extracting actionable insights from raw dataBook Description Practical Data Science with Python teaches you core data science concepts, with real-world and realistic examples, and strengthens your grip on the basic as well as advanced principles of data preparation and storage, statistics, probability theory, machine learning, and Python programming, helping you build a solid foundation to gain proficiency in data science. The book starts with an overview of basic Python skills and then introduces foundational data science techniques, followed by a thorough explanation of the Python code needed to execute the techniques. You'll understand the code by working through the examples. The code has been broken down into small chunks (a few lines or a function at a time) to enable thorough discussion. As you progress, you will learn how to perform data analysis while exploring the functionalities of key data science Python packages, including pandas, SciPy, and scikit-learn. Finally, the book covers ethics and privacy concerns in data science and suggests resources for improving data science skills, as well as ways to stay up to date on new data science developments. By the end of the book, you should be able to comfortably use Python for basic data science projects and should have the skills to execute the data science process on any data source. What you will learnUse Python data science packages effectivelyClean and prepare data for data science work, including feature engineering and feature selectionData modeling, including classic statistical models (such as t-tests), and essential machine learning algorithms, such as random forests and boosted modelsEvaluate model performanceCompare and understand different machine learning methodsInteract with Excel spreadsheets through PythonCreate automated data science reports through PythonGet to grips with text analytics techniquesWho this book is for The book is intended for beginners, including students starting or about to start a data science, analytics, or related program (e.g. Bachelor’s, Master’s, bootcamp, online courses), recent college graduates who want to learn new skills to set them apart in the job market, professionals who want to learn hands-on data science techniques in Python, and those who want to shift their career to data science. The book requires basic familiarity with Python. A "getting started with Python" section has been included to get complete novices up to speed.

Managing Your Biological Data with Python

Author : Allegra Via,Kristian Rother,Anna Tramontano
Publisher : CRC Press
Page : 560 pages
File Size : 45,6 Mb
Release : 2014-03-18
Category : Computers
ISBN : 9781439880944

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Managing Your Biological Data with Python by Allegra Via,Kristian Rother,Anna Tramontano Pdf

Take Control of Your Data and Use Python with ConfidenceRequiring no prior programming experience, Managing Your Biological Data with Python empowers biologists and other life scientists to work with biological data on their own using the Python language. The book teaches them not only how to program but also how to manage their data. It shows how

Data Science Using Python and R

Author : Chantal D. Larose,Daniel T. Larose
Publisher : John Wiley & Sons
Page : 256 pages
File Size : 41,6 Mb
Release : 2019-04-09
Category : Computers
ISBN : 9781119526810

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Data Science Using Python and R by Chantal D. Larose,Daniel T. Larose Pdf

Learn data science by doing data science! Data Science Using Python and R will get you plugged into the world’s two most widespread open-source platforms for data science: Python and R. Data science is hot. Bloomberg called data scientist “the hottest job in America.” Python and R are the top two open-source data science tools in the world. In Data Science Using Python and R, you will learn step-by-step how to produce hands-on solutions to real-world business problems, using state-of-the-art techniques. Data Science Using Python and R is written for the general reader with no previous analytics or programming experience. An entire chapter is dedicated to learning the basics of Python and R. Then, each chapter presents step-by-step instructions and walkthroughs for solving data science problems using Python and R. Those with analytics experience will appreciate having a one-stop shop for learning how to do data science using Python and R. Topics covered include data preparation, exploratory data analysis, preparing to model the data, decision trees, model evaluation, misclassification costs, naïve Bayes classification, neural networks, clustering, regression modeling, dimension reduction, and association rules mining. Further, exciting new topics such as random forests and general linear models are also included. The book emphasizes data-driven error costs to enhance profitability, which avoids the common pitfalls that may cost a company millions of dollars. Data Science Using Python and R provides exercises at the end of every chapter, totaling over 500 exercises in the book. Readers will therefore have plenty of opportunity to test their newfound data science skills and expertise. In the Hands-on Analysis exercises, readers are challenged to solve interesting business problems using real-world data sets.

Introduction to Data Science

Author : Laura Igual,Santi Seguí
Publisher : Springer
Page : 218 pages
File Size : 43,6 Mb
Release : 2017-02-22
Category : Computers
ISBN : 9783319500171

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Introduction to Data Science by Laura Igual,Santi Seguí Pdf

This accessible and classroom-tested textbook/reference presents an introduction to the fundamentals of the emerging and interdisciplinary field of data science. The coverage spans key concepts adopted from statistics and machine learning, useful techniques for graph analysis and parallel programming, and the practical application of data science for such tasks as building recommender systems or performing sentiment analysis. Topics and features: provides numerous practical case studies using real-world data throughout the book; supports understanding through hands-on experience of solving data science problems using Python; describes techniques and tools for statistical analysis, machine learning, graph analysis, and parallel programming; reviews a range of applications of data science, including recommender systems and sentiment analysis of text data; provides supplementary code resources and data at an associated website.

Practical Statistics for Data Scientists

Author : Peter Bruce,Andrew Bruce
Publisher : "O'Reilly Media, Inc."
Page : 395 pages
File Size : 43,6 Mb
Release : 2017-05-10
Category : Computers
ISBN : 9781491952917

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Practical Statistics for Data Scientists by Peter Bruce,Andrew Bruce Pdf

Statistical methods are a key part of of data science, yet very few data scientists have any formal statistics training. Courses and books on basic statistics rarely cover the topic from a data science perspective. This practical guide explains how to apply various statistical methods to data science, tells you how to avoid their misuse, and gives you advice on what's important and what's not. Many data science resources incorporate statistical methods but lack a deeper statistical perspective. If you’re familiar with the R programming language, and have some exposure to statistics, this quick reference bridges the gap in an accessible, readable format. With this book, you’ll learn: Why exploratory data analysis is a key preliminary step in data science How random sampling can reduce bias and yield a higher quality dataset, even with big data How the principles of experimental design yield definitive answers to questions How to use regression to estimate outcomes and detect anomalies Key classification techniques for predicting which categories a record belongs to Statistical machine learning methods that “learn” from data Unsupervised learning methods for extracting meaning from unlabeled data

All About Bioinformatics

Author : Yasha Hasija
Publisher : Elsevier
Page : 314 pages
File Size : 53,6 Mb
Release : 2023-04-05
Category : Science
ISBN : 9780443152511

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All About Bioinformatics by Yasha Hasija Pdf

All About Bioinformatics: From Beginner to Expert provides readers with an overview of the fundamentals and advances in the _x001F_field of bioinformatics, as well as some future directions. Each chapter is didactically organized and includes introduction, applications, tools, and future directions to cover the topics thoroughly. The book covers both traditional topics such as biological databases, algorithms, genetic variations, static methods, and structural bioinformatics, as well as contemporary advanced topics such as high-throughput technologies, drug informatics, system and network biology, and machine learning. It is a valuable resource for researchers and graduate students who are interested to learn more about bioinformatics to apply in their research work. Presents a holistic learning experience, beginning with an introduction to bioinformatics to recent advancements in the field Discusses bioinformatics as a practice rather than in theory focusing on more application-oriented topics as high-throughput technologies, system and network biology, and workflow management systems Encompasses chapters on statistics and machine learning to assist readers in deciphering trends and patterns in biological data

Data Science Projects with Python

Author : Stephen Klosterman
Publisher : Unknown
Page : 432 pages
File Size : 47,5 Mb
Release : 2021-07-29
Category : Electronic
ISBN : 1800564481

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Data Science Projects with Python by Stephen Klosterman Pdf

Gain hands-on experience of Python programming with industry-standard machine learning techniques using pandas, scikit-learn, and XGBoost Key Features Think critically about data and use it to form and test a hypothesis Choose an appropriate machine learning model and train it on your data Communicate data-driven insights with confidence and clarity Book Description If data is the new oil, then machine learning is the drill. As companies gain access to ever-increasing quantities of raw data, the ability to deliver state-of-the-art predictive models that support business decision-making becomes more and more valuable. In this book, you'll work on an end-to-end project based around a realistic data set and split up into bite-sized practical exercises. This creates a case-study approach that simulates the working conditions you'll experience in real-world data science projects. You'll learn how to use key Python packages, including pandas, Matplotlib, and scikit-learn, and master the process of data exploration and data processing, before moving on to fitting, evaluating, and tuning algorithms such as regularized logistic regression and random forest. Now in its second edition, this book will take you through the end-to-end process of exploring data and delivering machine learning models. Updated for 2021, this edition includes brand new content on XGBoost, SHAP values, algorithmic fairness, and the ethical concerns of deploying a model in the real world. By the end of this data science book, you'll have the skills, understanding, and confidence to build your own machine learning models and gain insights from real data. What you will learn Load, explore, and process data using the pandas Python package Use Matplotlib to create compelling data visualizations Implement predictive machine learning models with scikit-learn Use lasso and ridge regression to reduce model overfitting Evaluate random forest and logistic regression model performance Deliver business insights by presenting clear, convincing conclusions Who this book is for Data Science Projects with Python - Second Edition is for anyone who wants to get started with data science and machine learning. If you're keen to advance your career by using data analysis and predictive modeling to generate business insights, then this book is the perfect place to begin. To quickly grasp the concepts covered, it is recommended that you have basic experience of programming with Python or another similar language, and a general interest in statistics.

Practical Machine Learning for Data Analysis Using Python

Author : Abdulhamit Subasi
Publisher : Academic Press
Page : 534 pages
File Size : 45,9 Mb
Release : 2020-06-05
Category : Computers
ISBN : 9780128213803

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Practical Machine Learning for Data Analysis Using Python by Abdulhamit Subasi Pdf

Practical Machine Learning for Data Analysis Using Python is a problem solver’s guide for creating real-world intelligent systems. It provides a comprehensive approach with concepts, practices, hands-on examples, and sample code. The book teaches readers the vital skills required to understand and solve different problems with machine learning. It teaches machine learning techniques necessary to become a successful practitioner, through the presentation of real-world case studies in Python machine learning ecosystems. The book also focuses on building a foundation of machine learning knowledge to solve different real-world case studies across various fields, including biomedical signal analysis, healthcare, security, economics, and finance. Moreover, it covers a wide range of machine learning models, including regression, classification, and forecasting. The goal of the book is to help a broad range of readers, including IT professionals, analysts, developers, data scientists, engineers, and graduate students, to solve their own real-world problems. Offers a comprehensive overview of the application of machine learning tools in data analysis across a wide range of subject areas Teaches readers how to apply machine learning techniques to biomedical signals, financial data, and healthcare data Explores important classification and regression algorithms as well as other machine learning techniques Explains how to use Python to handle data extraction, manipulation, and exploration techniques, as well as how to visualize data spread across multiple dimensions and extract useful features

Hands-On Data Analysis with Pandas

Author : Stefanie Molin
Publisher : Packt Publishing Ltd
Page : 788 pages
File Size : 43,9 Mb
Release : 2021-04-29
Category : Computers
ISBN : 9781800565913

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Hands-On Data Analysis with Pandas by Stefanie Molin Pdf

Get to grips with pandas by working with real datasets and master data discovery, data manipulation, data preparation, and handling data for analytical tasks Key Features Perform efficient data analysis and manipulation tasks using pandas 1.x Apply pandas to different real-world domains with the help of step-by-step examples Make the most of pandas as an effective data exploration tool Book DescriptionExtracting valuable business insights is no longer a ‘nice-to-have’, but an essential skill for anyone who handles data in their enterprise. Hands-On Data Analysis with Pandas is here to help beginners and those who are migrating their skills into data science get up to speed in no time. This book will show you how to analyze your data, get started with machine learning, and work effectively with the Python libraries often used for data science, such as pandas, NumPy, matplotlib, seaborn, and scikit-learn. Using real-world datasets, you will learn how to use the pandas library to perform data wrangling to reshape, clean, and aggregate your data. Then, you will learn how to conduct exploratory data analysis by calculating summary statistics and visualizing the data to find patterns. In the concluding chapters, you will explore some applications of anomaly detection, regression, clustering, and classification using scikit-learn to make predictions based on past data. This updated edition will equip you with the skills you need to use pandas 1.x to efficiently perform various data manipulation tasks, reliably reproduce analyses, and visualize your data for effective decision making – valuable knowledge that can be applied across multiple domains.What you will learn Understand how data analysts and scientists gather and analyze data Perform data analysis and data wrangling using Python Combine, group, and aggregate data from multiple sources Create data visualizations with pandas, matplotlib, and seaborn Apply machine learning algorithms to identify patterns and make predictions Use Python data science libraries to analyze real-world datasets Solve common data representation and analysis problems using pandas Build Python scripts, modules, and packages for reusable analysis code Who this book is for This book is for data science beginners, data analysts, and Python developers who want to explore each stage of data analysis and scientific computing using a wide range of datasets. Data scientists looking to implement pandas in their machine learning workflow will also find plenty of valuable know-how as they progress. You’ll find it easier to follow along with this book if you have a working knowledge of the Python programming language, but a Python crash-course tutorial is provided in the code bundle for anyone who needs a refresher.

Hands-On Data Preprocessing in Python

Author : Roy Jafari
Publisher : Packt Publishing Ltd
Page : 602 pages
File Size : 48,5 Mb
Release : 2022-01-21
Category : Computers
ISBN : 9781801079952

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Hands-On Data Preprocessing in Python by Roy Jafari Pdf

Get your raw data cleaned up and ready for processing to design better data analytic solutions Key FeaturesDevelop the skills to perform data cleaning, data integration, data reduction, and data transformationMake the most of your raw data with powerful data transformation and massaging techniquesPerform thorough data cleaning, including dealing with missing values and outliersBook Description Hands-On Data Preprocessing is a primer on the best data cleaning and preprocessing techniques, written by an expert who's developed college-level courses on data preprocessing and related subjects. With this book, you'll be equipped with the optimum data preprocessing techniques from multiple perspectives, ensuring that you get the best possible insights from your data. You'll learn about different technical and analytical aspects of data preprocessing – data collection, data cleaning, data integration, data reduction, and data transformation – and get to grips with implementing them using the open source Python programming environment. The hands-on examples and easy-to-follow chapters will help you gain a comprehensive articulation of data preprocessing, its whys and hows, and identify opportunities where data analytics could lead to more effective decision making. As you progress through the chapters, you'll also understand the role of data management systems and technologies for effective analytics and how to use APIs to pull data. By the end of this Python data preprocessing book, you'll be able to use Python to read, manipulate, and analyze data; perform data cleaning, integration, reduction, and transformation techniques, and handle outliers or missing values to effectively prepare data for analytic tools. What you will learnUse Python to perform analytics functions on your dataUnderstand the role of databases and how to effectively pull data from databasesPerform data preprocessing steps defined by your analytics goalsRecognize and resolve data integration challengesIdentify the need for data reduction and execute itDetect opportunities to improve analytics with data transformationWho this book is for This book is for junior and senior data analysts, business intelligence professionals, engineering undergraduates, and data enthusiasts looking to perform preprocessing and data cleaning on large amounts of data. You don't need any prior experience with data preprocessing to get started with this book. However, basic programming skills, such as working with variables, conditionals, and loops, along with beginner-level knowledge of Python and simple analytics experience, are a prerequisite.

Bioinformatics with Python Cookbook

Author : Tiago Antao
Publisher : Packt Publishing Ltd
Page : 352 pages
File Size : 51,7 Mb
Release : 2018-11-30
Category : Computers
ISBN : 9781789349986

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Bioinformatics with Python Cookbook by Tiago Antao Pdf

Discover modern, next-generation sequencing libraries from Python ecosystem to analyze large amounts of biological data Key Features Perform complex bioinformatics analysis using the most important Python libraries and applications Implement next-generation sequencing, metagenomics, automating analysis, population genetics, and more Explore various statistical and machine learning techniques for bioinformatics data analysis Book Description Bioinformatics is an active research field that uses a range of simple-to-advanced computations to extract valuable information from biological data. This book covers next-generation sequencing, genomics, metagenomics, population genetics, phylogenetics, and proteomics. You'll learn modern programming techniques to analyze large amounts of biological data. With the help of real-world examples, you'll convert, analyze, and visualize datasets using various Python tools and libraries. This book will help you get a better understanding of working with a Galaxy server, which is the most widely used bioinformatics web-based pipeline system. This updated edition also includes advanced next-generation sequencing filtering techniques. You'll also explore topics such as SNP discovery using statistical approaches under high-performance computing frameworks such as Dask and Spark. By the end of this book, you'll be able to use and implement modern programming techniques and frameworks to deal with the ever-increasing deluge of bioinformatics data. What you will learn Learn how to process large next-generation sequencing (NGS) datasets Work with genomic dataset using the FASTQ, BAM, and VCF formats Learn to perform sequence comparison and phylogenetic reconstruction Perform complex analysis with protemics data Use Python to interact with Galaxy servers Use High-performance computing techniques with Dask and Spark Visualize protein dataset interactions using Cytoscape Use PCA and Decision Trees, two machine learning techniques, with biological datasets Who this book is for This book is for Data data Scientistsscientists, Bioinformatics bioinformatics analysts, researchers, and Python developers who want to address intermediate-to-advanced biological and bioinformatics problems using a recipe-based approach. Working knowledge of the Python programming language is expected.

Python for the Life Sciences

Author : Alexander Lancaster,Gordon Webster
Publisher : Apress
Page : 396 pages
File Size : 52,5 Mb
Release : 2019-09-27
Category : Computers
ISBN : 9781484245231

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Python for the Life Sciences by Alexander Lancaster,Gordon Webster Pdf

Treat yourself to a lively, intuitive, and easy-to-follow introduction to computer programming in Python. The book was written specifically for biologists with little or no prior experience of writing code - with the goal of giving them not only a foundation in Python programming, but also the confidence and inspiration to start using Python in their own research. Virtually all of the examples in the book are drawn from across a wide spectrum of life science research, from simple biochemical calculations and sequence analysis, to modeling the dynamic interactions of genes and proteins in cells, or the drift of genes in an evolving population. Best of all, Python for the Life Sciences shows you how to implement all of these projects in Python, one of the most popular programming languages for scientific computing. If you are a life scientist interested in learning Python to jump-start your research, this is the book for you. What You'll Learn Write Python scripts to automate your lab calculations Search for important motifs in genome sequences Use object-oriented programming with Python Study mining interaction network data for patterns Review dynamic modeling of biochemical switches Who This Book Is For Life scientists with little or no programming experience, including undergraduate and graduate students, postdoctoral researchers in academia and industry, medical professionals, and teachers/lecturers. “A comprehensive introduction to using Python for computational biology... A lovely book with humor and perspective” -- John Novembre, Associate Professor of Human Genetics, University of Chicago and MacArthur Fellow “Fun, entertaining, witty and darn useful. A magical portal to the big data revolution” -- Sandro Santagata, Assistant Professor in Pathology, Harvard Medical School “Alex and Gordon’s enthusiasm for Python is contagious” -- Glenys Thomson Professor of Integrative Biology, University of California, Berkeley