Health Impacts Of Developmental Exposure To Environmental Chemicals

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Health Impacts of Developmental Exposure to Environmental Chemicals

Reiko Kishi,Philippe Grandjean
Health Impacts of Developmental Exposure to Environmental Chemicals Book PDF

Author : Reiko Kishi,Philippe Grandjean
Publisher : Springer Nature
Page : 554 pages
File Size : 40,6 Mb
Release : 2019-12-13
Category : Medical
ISBN : 9789811505201

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Health Impacts of Developmental Exposure to Environmental Chemicals by Reiko Kishi,Philippe Grandjean Pdf

This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to the impacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children’s environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects. Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children’s health can be affected by harmful chemicals and other environmental toxicants.

Health Impacts of Developmental Exposure to Environmental Chemicals

Reiko Kishi,Philippe Grandjean
Health Impacts of Developmental Exposure to Environmental Chemicals Book PDF

Author : Reiko Kishi,Philippe Grandjean
Publisher : Unknown
Page : 0 pages
File Size : 49,7 Mb
Release : 2020
Category : Electronic books
ISBN : 9811505217

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Health Impacts of Developmental Exposure to Environmental Chemicals by Reiko Kishi,Philippe Grandjean Pdf

This book provides concise and cutting-edge studies on threats resulting from exposure to environmental chemicals that can affect human health and development, with a particular emphasis on the DOHaD concept. The book is divided into five main parts, the first of which includes an introduction to theimpacts of developmental exposure to environmental chemicals and historical perspectives, while the second focuses on how environmental chemicals can affect human organs, including neurodevelopment, immune functions, etc. In turn, the third part addresses the characteristics of specific chemicals and their effects on human health and development, while the fourth part provides a basis for future studies by highlighting the latest innovations in toxicology, remaining challenges, and promising strategies in children's environmental health research, as well as ideas on how to bridge the gap between research evidence and practical policymaking. The fifth and last part outlines further research directions and related policymaking aspects. Health Impacts of Developmental Exposure to Environmental Chemicals will appeal to young and veteran researchers, students, and physicians (especially gynecologists and pediatricians) who are seeking comprehensive information on how children's health can be affected by harmful chemicals and other environmental toxicants.

Principles for Evaluating Health Risks in Children Associated with Exposure to Chemicals

Germaine Buck Louis,United Nations Environment Programme,International Labour Organisation,World Health Organization
Principles for Evaluating Health Risks in Children Associated with Exposure to Chemicals Book PDF

Author : Germaine Buck Louis,United Nations Environment Programme,International Labour Organisation,World Health Organization
Publisher : World Health Organization
Page : 352 pages
File Size : 47,8 Mb
Release : 2006
Category : Medical
ISBN : 9789241572378

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Principles for Evaluating Health Risks in Children Associated with Exposure to Chemicals by Germaine Buck Louis,United Nations Environment Programme,International Labour Organisation,World Health Organization Pdf

Conclusions, and recommendations -- Introduction and background -- Unique biological characteristics of children -- Developmental stage-specific susceptibilities and outcomes in children -- Exposure assessment of children -- Methodologies to assess health outcomes in children -- Implications and strategies for risk assessment for children.

Reproductive Health and the Environment

P. Nicolopoulou-Stamati,L. Hens,C.V. Howard
Reproductive Health and the Environment Book PDF

Author : P. Nicolopoulou-Stamati,L. Hens,C.V. Howard
Publisher : Springer Science & Business Media
Page : 392 pages
File Size : 53,8 Mb
Release : 2007-06-04
Category : Medical
ISBN : 9781402048296

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Reproductive Health and the Environment by P. Nicolopoulou-Stamati,L. Hens,C.V. Howard Pdf

This book reviews recent trends and developments in the study of the impact that the environment has on human reproduction. It thoroughly examines these issues, using the most modern techniques and methods available, to analyze the manner in which both male and female fertility can be affected and assessed. Coverage examines such diverse factors as toxic environmental contaminants, air pollution, and exposure to medical drugs.

Phthalates and Cumulative Risk Assessment

National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on the Health Risks of Phthalates
Phthalates and Cumulative Risk Assessment Book PDF

Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on the Health Risks of Phthalates
Publisher : National Academies Press
Page : 208 pages
File Size : 50,7 Mb
Release : 2009-01-19
Category : Nature
ISBN : 9780309128414

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Phthalates and Cumulative Risk Assessment by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on the Health Risks of Phthalates Pdf

People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Textbook of Children's Environmental Health

Philip J. Landrigan,Ruth A. Etzel
Textbook of Children s Environmental Health Book PDF

Author : Philip J. Landrigan,Ruth A. Etzel
Publisher : Oxford University Press
Page : 608 pages
File Size : 55,9 Mb
Release : 2013-11-15
Category : Medical
ISBN : 9780199336654

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Textbook of Children's Environmental Health by Philip J. Landrigan,Ruth A. Etzel Pdf

Over the past four decades, the prevalence of autism, asthma, ADHD, obesity, diabetes, and birth defects have grown substantially among children around the world. Not coincidentally, more than 80,000 new chemicals have been developed and released into the global environment during this same period. Today the World Health Organization attributes 36% of all childhood deaths to environmental causes. Children's environmental health is a new and expanding discipline that studies the profound impact of chemical and environmental hazards on child health. Amid mounting evidence that children are exquisitely sensitive to their environment-and that exposure during their developmental "windows of susceptibility" can trigger cellular changes that lead to disease and disability in infancy, childhood, and across the life span-there is a compelling need for continued scientific study of the relationship between children's health and environment. The Textbook of Children's Environmental Health codifies the knowledge base and offers an authoritative and comprehensive guide to this important new field. Edited by two internationally recognized pioneers in the area, this volume presents up-to-date information on the chemical, biological, physical, and societal hazards that confront children in today's world: pesticides, indoor and outdoor air pollution, lead, arsenic, phthalates, bisphenol A, brominated flame retardants, ionizing radiation, electromagnetic fields, and the built environment. It presents carefully documented data on rising rates of disease in children, offers a critical summary of new research linking pediatric disease with environmental exposures, and explores the cellular, molecular, and epigenetic mechanisms underlying diseases of environmental origin. With this volume's emphasis upon integrating theory and practice, readers will find practical approaches to channeling scientific findings into evidence-based strategies for preventing and identifying the environmental hazards that cause disease in children. It is a landmark work that will serve as the field's benchmark for years to come.

Early-life Environmental Exposure and Disease

Yankai Xia
Early life Environmental Exposure and Disease Book PDF

Author : Yankai Xia
Publisher : Springer Nature
Page : 246 pages
File Size : 42,7 Mb
Release : 2020-07-09
Category : Medical
ISBN : 9789811537974

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Early-life Environmental Exposure and Disease by Yankai Xia Pdf

This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health.

Child Health and the Environment

Donald T. Wigle
Child Health and the Environment Book PDF

Author : Donald T. Wigle
Publisher : Oxford University Press
Page : 416 pages
File Size : 52,9 Mb
Release : 2003-03-20
Category : Medical
ISBN : 9780190285654

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Child Health and the Environment by Donald T. Wigle Pdf

This is the first textbook to focus on environmental threats to child health. It will interest professionals and graduate students in public health, pediatrics, environmental health, epidemiology, and toxicology. The first three chapters provide overviews of key children's environmental health issues as well as the role of environmental epidemiology and risk assessment in child health protection. Overarching themes are the susceptibility of the rapidly developing fetus and infant to environmental toxicants, the importance of modifying factors(e.g. poverty, genetic traits, nutrition), the role of health outcome and exposure monitoring, uncertainties surrounding environmental exposure limits, and the importance of timely intervention. Later chapters address the health effects of metals, PCBs, dioxins, pesticides, hormonally active agents, radiation, indoor and outdoor air pollution, and water contaminants. In analyzing potential environmental hazards, the author addresses both biologic and epidemiologic evidence, including the likelihood of causal relationships. Among the health outcomes he discusses are developmental, reproductive, and neurobehavioral effects, respiratory disease, cancer, and waterborne infectious diseases. These discussions cover environmental exposure sources/indicators, interventions, and standards, and conclude with a summary of calls for an improved science base to guide public health decisions and protect child health.

Developmental Exposure to Environmental Contaminants

Kimberly Keil Stietz,Tracie Baker,Jessica Plavicki
Developmental Exposure to Environmental Contaminants Book PDF

Author : Kimberly Keil Stietz,Tracie Baker,Jessica Plavicki
Publisher : Unknown
Page : 0 pages
File Size : 42,5 Mb
Release : 2022
Category : Electronic
ISBN : 3036558853

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Developmental Exposure to Environmental Contaminants by Kimberly Keil Stietz,Tracie Baker,Jessica Plavicki Pdf

Development provides an especially sensitive window whereby environmental contaminants can have significant and lasting effects on the morphology and function of many organs and systems. The importance of understanding developmental effects of environmental contaminants extends not only to developmental stages, but also to encompass the hypotheses of the developmental or fetal origins of adult disease. Such effects of environmental contaminants during development extend to health outcomes that can persist in adulthood, first become apparent in adulthood, or manifest in adulthood but only after a second hit/stressor. The diverse nature of possible environmental contaminants, ranging from persistent organic pollutants to emerging contaminants of concern, along with the diverse range of health implications, including autism, diabetes, cancer, infertility, and lower urinary tract function, make understanding developmental effects of environmental contaminants an ever growing and important field of study.This Special Issue aims to explore a variety of topics in line with the aims and scope of Toxics. Specifically, topics related to the developmental effects of environmental contaminants and/or their metabolites on the molecular, cellular, tissue, organ, organ system or organism, including mechanisms of toxicity, metabolism, risk assessment and management, as well as multiple stressor impacts in the context of aging or disease progression following developmental exposures.

Generations at Risk

Ted Schettler
Generations at Risk Book PDF

Author : Ted Schettler
Publisher : MIT Press
Page : 438 pages
File Size : 48,5 Mb
Release : 1999
Category : Medical
ISBN : 0262692473

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Generations at Risk by Ted Schettler Pdf

Compelling evidence suggests that human exposure to some toxic chemicals can have lifelong and even intergenerational effects on reproduction and development. Generations at Risk presents compelling evidence that human exposure to some toxic chemicals can have lifelong and even intergenerational effects on human reproduction and development. The result of a collaboration involving public health professionals, physicians, environmental educators, and policy advocates, this book examines how scientific, social, economic, and political systems may fail to protect us from environmental and occupational toxicants. It is an important sourcebook for those concerned about their own health and that of their loved ones, as well as for medical and public health workers, community activists, policymakers, and industrial decision makers.

Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity

National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on Reproductive and Developmental Toxicology
Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity Book PDF

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on Reproductive and Developmental Toxicology
Publisher : National Academies Press
Page : 261 pages
File Size : 40,5 Mb
Release : 2001-04-13
Category : Nature
ISBN : 9780309073165

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Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on Reproductive and Developmental Toxicology Pdf

The United States Navy has been concerned for some time with protecting its military and civilian personnel from reproductive and developmental hazards in the workplace. As part of its efforts to reduce or eliminate exposure of Naval personnel and their families to reproductive and developmental toxicants, the Navy requested that the National Research Council (NRC) recommend an approach that can be used to evaluate chemicals and physical agents for their potential to cause reproductive and developmental toxicity. The NRC assigned this project to the Committee on Toxicology, which convened the Subcommittee on Reproductive and Developmental Toxicology, to prepare this report. In this report, the subcommittee recommends an approach for evaluating agents for potential reproductive and developmental toxicity and demonstrates how that approach can be used by the Navy. This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the NRC's Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report: James Chen (National Center for Toxicological Research), George Daston (Procter and Gamble Company), Jerry Heindel (National Institute of Environmental Health Sciences), Grace Lemasters (University of Cincinnati), and John Young (National Center for Toxicological Research).

Formaldehyde

Luoping Zhang
Formaldehyde Book PDF

Author : Luoping Zhang
Publisher : Royal Society of Chemistry
Page : 414 pages
File Size : 42,5 Mb
Release : 2018-05-24
Category : Science
ISBN : 9781782629733

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Formaldehyde by Luoping Zhang Pdf

Formaldehyde is virtually ubiquitous in the modern environment due to its cost-effective nature, its use in resin formation, and its preservative properties. Though formaldehyde is necessary for many products and processes important to the world’s economy, this economic dependence on formaldehyde comes at a cost to public health. Growth and consequent industrialization rely heavily on formaldehyde use. New buildings—residences, public places, and offices—are not only built with timber preserved by formaldehyde, but they are also furnished with wood, wool, and textile products that contain formaldehyde. The general population faces environmental exposure from indoor and outdoor air pollution, food, and even medicine. Scientific inquiry into formaldehyde exposure has grown in response. This book consolidates the new and established body of formaldehyde research in the scholarly community, focusing on exposure, genotoxicity, and adverse health outcomes. Through this resource, we hope to increase awareness of the broad range of health effects posed by formaldehyde exposure, and to encourage interdisciplinary interest, as well as research, into this pervasive compound—especially in the United States and China, where formaldehyde production and usage is high. This book will be useful to researchers of environmental and occupational exposure, students, and government regulators and anyone exposed to formaldehyde in the workplace and/or at home.

Reproductive and Developmental Toxicants

Eleanor Chelimsky
Reproductive and Developmental Toxicants Book PDF

Author : Eleanor Chelimsky
Publisher : DIANE Publishing
Page : 118 pages
File Size : 46,8 Mb
Release : 2000
Category : Electronic
ISBN : 0788186264

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Reproductive and Developmental Toxicants by Eleanor Chelimsky Pdf

Evaluates federal regulatory actions on environmental chemicals known to cause adverse reproductive and developmental outcomes. Identifies 30 environmental chemicals found to be of high concern because of the widespread acknowledgment of their reproductive and developmental consequences as toxicants. Determines the extent to which these chemicals are regulated by the federal government. Assesses the degree to which these regulatory actions are based on reproductive and developmental toxicity. Evaluates whether the regulatory protection currently provided to the public against reproductive and developmental disease is sufficient.

Environmental Neuroscience

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Health and Medicine Division,Board on Environmental Studies and Toxicology,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Environmental Neuroscience Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Health and Medicine Division,Board on Environmental Studies and Toxicology,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 87 pages
File Size : 54,8 Mb
Release : 2021-01-22
Category : Medical
ISBN : 9780309683098

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Environmental Neuroscience by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Health and Medicine Division,Board on Environmental Studies and Toxicology,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive effects. Early life exposures to chemicals can have permanent consequences for neurodevelopment and for neurodegeneration in later life. Toxic effects resulting from chemical exposure can interact with other risk factors such as prenatal stress, and persistence of some chemicals in the brain over time may result in cumulative toxicity. Because neurodevelopmental and neurodegenerative disorders - such as attention-deficit hyperactivity disorder and Parkinson's disease - cannot be fully explained by genetic risk factors alone, understanding the role of individual environmental chemical exposures is critical. On June 25, 2020, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop to lay the foundation for future advances in environmental neuroscience. The workshop was designed to explore new opportunities to bridge the gap between what is known about the genetic contribution to brain disorders and what is known, and not known, about the contribution of environmental influences, as well as to discuss what is known about how genetic and environmental factors interact. This publication summarizes the presentation and discussion of the workshop.

Drinking Water and Health,

National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee
Drinking Water and Health Book PDF

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee
Publisher : National Academies Press
Page : 476 pages
File Size : 53,7 Mb
Release : 1986-02-01
Category : Nature
ISBN : 9780309036870

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Drinking Water and Health, by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee Pdf

The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.