Hematopoietic Growth Factors In Clinical Applications Second Edition
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Hematopoietic Growth Factors in Clinical Applications, Second Edition, by Roland Mertelsmann,Friedhelm Herrmann Pdf
The Second Edition contains a wealth of new information on cytokines and the self-renewal, proliferation, maturation, and state of activity of hematopoietic and immunological progenitor cells and their progeny-demonstrating their efficacy in treating disease states associated with hematopoietic failure or impaired blood cell function. Discusses the demonstrated and potential clinical benefits of hematopoietic growth factors, the economic consequences of using these agents, and various practical usage concerns!
Hematopoietic Growth Factors in Clinical Applications by Roland Mertelsmann,S. Gillis Pdf
The Second Edition contains a wealth of new information on cytokines and the self-renewal, proliferation, maturation, and state of activity of hematopoietic and immunological progenitor cells and their progeny-demonstrating their efficacy in treating disease states associated with hematopoietic failure or impaired blood cell function. Discusses the demonstrated and potential clinical benefits of hematopoietic growth factors, the economic consequences of using these agents, and various practical usage concerns!
Hematopoietic Growth Factors in Clinical Applications by Roland Mertelsmann,Friedhelm Herrmann Pdf
The Second Edition contains a wealth of new information on cytokines and the self-renewal, proliferation, maturation, and state of activity of hematopoietic and immunological progenitor cells and their progeny-demonstrating their efficacy in treating disease states associated with hematopoietic failure or impaired blood cell function. Discusses the demonstrated and potential clinical benefits of hematopoietic growth factors, the economic consequences of using these agents, and various practical usage concerns!
Author : John R. Wingard,George D. Demetri Publisher : Springer Science & Business Media Page : 424 pages File Size : 44,8 Mb Release : 2012-12-06 Category : Medical ISBN : 9781461550136
Clinical Applications of Cytokines and Growth Factors by John R. Wingard,George D. Demetri Pdf
The hematopoietic system plays roles that are crucial for survival of the host: delivery of oxygen to tissues, arrest of accidental blood leaking from blood vessels, and fending off of invading microbes by humoral, cell-mediated, and phagocytic immunity. The activity of the hematopoietic system is staggering: daily, a normal adult produces approximately 2.5 billion erythrocytes, 2.5 billion platelets, and 1 billion granulocytes per kilogram of body weight. This production is adjusted in a timely fashion to changes in actual needs and can vary from nearly none to many times the normal rate depending on needs which vary from day to day, or even minute to minute. In response to a variety of stimuli, the cellular components of the blood are promptly increased or decreased in production to maintain appropriate numbers to optimally protect the host from hypoxia, infection, and hemorrhage. How does this all happen and happen without over or under responding? There has been extraordinary growth in our understanding ofhematopoiesis over the last two decades. Occupying center stage is the pluripotent stern cell and its progeny. Hematopoietic stern cells have been characterized by their capacity for self renewal and their ability to proliferate and differentiate along multiple lineages. Few in number, the stern cell gives rise to all circulating neutrophils, erythrocytes, lymphoid cells, and platelets. In hematopoietic transplantation, the stern cell is capable of restoring long-term hematopoiesis in a lethally irradiated host.
Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.
Hematopoietic Growth Factors in Oncology by George Morstyn,MaryAnn Foote,Graham J. Lieschke Pdf
Whether to promote platelet recovery or to ameliorate the complications of cancer and the side effects of chemotherapy, hematopoietic growth factors (HGFs) now account for more than $5 billion per year of the US health care budget. In Hematopoietic Growth Factors in Oncology: Basic Science and Clinical Therapeutics, leading oncologists, hematologists, and nephrologists comprehensively review the role of HGFs in clinical practice, explain the molecular basis of their effects, and consider potential future developments. The authors focus on the use of HGFs in oncology, describing their cutting-edge application to patients with lung cancer, Hodgkin's and non-Hodgkin's lymphoma, breast cancer, chronic lymphocytic leukemia, AIDS-related malignancies, myelodysplastic syndromes, and aplastic anemias. Among the HGFs described are granulocyte colony-stimulating factor, erythropoietc factors, thrombopoietic factors, and stem-cell factor and its receptor, c-kit. To complete their survey, the contributors also consider the safety and economic implications of HGFs and the future potential for HGF antagonists in oncology. Comprehensive and up-to-date, Hematopoietic Growth Factors in Oncology: Basic Science and Clinical Practice offers an integrated survey of the role of HGFs in treating and preventing anemia, neutropenia, and thrombocytopenia in patients with malignant and nonmalignant diseases, along with fresh insights into drug development and how basic discoveries in this area can be optimally translated into clinical benefit.
Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy
Author : Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy Publisher : Unknown Page : 637 pages File Size : 42,8 Mb Release : 2013-06-04 Category : Hematology ISBN : 0982843518
American Society of Hematology Self-Assessment Program by Timothy Graubert,James R. Cook,Laura Scheuttpelz,Donald M. Arnold,Adam Cuker,Cindy Neunert,Keith R. McCrae,Margaret Ragni,Sarah O'Brien,Murat Arcasoy,Gary Lyman,Marc J. Kahn,Lawrence A. Solberg,Jecko Thachil,Timothy James Littlewood,Sioban Keel,Charles T. Quinn,Charles H. Packman,Stephan Moll,David Garcia,David P. Steensma,Anjali Sharathkumar,Jorge Di Paola,Amy D. Shapiro,A. Koneti Rao,Charles Eby,Jacob Rand,John Frater,Karen Quillen,Suzanne Bakdash,Dan S. Kaufman,David T. Scadden,Jerald Radich,Sergio Giralt,Geoffrey L. Uy,Inderjeet Dokal,Ross Levine,Ramon V. Tiu,Phillip Scheinberg,Lillian Sung,B. Douglas Smith,Daniel J. DeAngelo,Ching-Hon Pui,Kristie A. Blum,Ann LaCasce,Kerry Joanne Savage,Brad S. Kahl,Grzegorz S. Nowakowski,Vicki A. Morrison,Irene Ghobrial,Martha Lacy Pdf
Hematologists and others working in hematology-related fields need to stay current with the latest advances in the rapidly evolving disciplines of adult and pediatric hematology. The American Society of Hematology Self-Assessment Program (ASH-SAP) is the only complete, comprehensive, educational resource available that fulfills this need, while also providing thorough board and recertification preparation, as well as AMA PRA Category 1 Credit'.
Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum
Author : Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum Publisher : John Wiley & Sons Page : 1416 pages File Size : 52,9 Mb Release : 2015-12-14 Category : Medical ISBN : 9781118416129
Thomas' Hematopoietic Cell Transplantation by Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum Pdf
Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.
Comprehensive Geriatric Oncology, Second Edition by Lodovico Balducci,William B. Ershler,Gary H. Lyman,Martine Extermann Pdf
The prevention and treatment of cancer in older patients requires an individualized approach, as age causes unpredictable results from patient to patient. Completely revised and updated, the Second Edition of Comprehensive Geriatric Oncology enables clinicians to choose the best possible cancer care. Highlighting newly emerging issues in geriatric oncology, it helps physicians promote cancer prevention. Like its groundbreaking, bestselling predecessor, this new edition exhaustively reviews the biology of cancer and aging, epidemiologic trends, and clinical trials that concern cancer prevention and treatment in the elderly. New chapters contain material on topics such as assessment, fragility, symptom management, and emergencies, and studies the effectiveness of training programs in geriatric oncology. The book addresses issues of healthcare delivery, including cost and evaluation of utility and outcome, suggests new research approaches, reviews existing guidelines for the prevention and treatment of cancer in the elderly, and more. Providing a frame of reference for the ongoing dialogue in the field of geriatric oncology, this is a major reference work for basic, population, and clinical scientists interested in the issue and for practices ministering to older patients.
Veterinary Clinical Pathology Secrets E-Book by Rick L. Cowell Pdf
Part of the popular SECRETS SERIES®, this all-new text provides essential, practical information for reviewing pathology commonly encountered in clinical situations. Organized by disorder type, it features numerous photos, a popular question-and-answer format, and a detailed index that makes it easy to find information quickly. In more than 50 chapters, expert contributors propose key questions and provide authoritative answers addressing the situations that confront small animal veterinarians every day. Comprehensive coverage of pathology is offered by a team of nationally recognized veterinary pathology experts. All of the most important "need to know" questions and answers are provided in the proven format of the acclaimed Secrets Series. More than 150 superior-quality photos highlight key concepts. A thorough, highly detailed index provides quick and easy access to specific topics.
Integrating Conventional and Chinese Medicine in Cancer Care by Tai Lahans Pdf
This new clinical resource clearly explains how to approach integrated care in a way that combines Chinese herbal medicine with Western medicine to enhance and improve medical care for patients with cancer - without undermining or negatively impacting patients' medical treatment. Each chapter covers a different type of cancer, first introducing the conventional medical understanding of that cancer including its etiology, diagnosis, and treatment according to staging and type. The chapter then covers that cancer from the perspective of Oriental medicine. Case studies illustrate the integration of treatment for each cancer type, raising important issues and considerations associated with specific cancers and treatments. Formulas are presented within the context of conventional treatment, intended to enhance the effectiveness of treatment and/or treat side effects without undermining the treatment's function. Each formula is followed by a discussion of how and why the herbs are used, including classical Chinese theory and relevant pharmaceutical studies. Staging and the age and performance status of various patients is used as a means by which to explain how formulas are changed. Case studies explore issues related to the integration of treatment for each type of cancer.
Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback
Author : Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback Publisher : Elsevier Health Sciences Page : 910 pages File Size : 42,9 Mb Release : 2006-10-18 Category : Medical ISBN : 9780443069819
Blood Banking and Transfusion Medicine by Christopher D. Hillyer,Leslie E. Silberstein,Paul M. Ness,Kenneth C. Anderson,John D. Roback Pdf
Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
