Histological Analysis Of Endocrine Disruptive Effects In Small Laboratory Fish
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Histological Analysis of Endocrine Disruptive Effects in Small Laboratory Fish by Daniel Dietrich,Heiko O. Krieger Pdf
Timely title assembling the combined knowledge of some of the leading authorities in the field of small fish reproduction - an important topic for risk assessment and registration of chemical, agricultural, and pharmaceutical compounds Provides guidance on the microscopic structure of living tissue and evaluation of the reproductive glands of small laboratory fish Includes state-of-the-art science along with sufficient anatomical and physiological background for understanding and interpreting test results Helps standardize the interpretation of results from aquatic bioassays and field observations, which will also clarify inconsistencies in the current scientific literature Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Sediment Quality Assessment by Graeme Batley,Stuart Simpson Pdf
Contaminated sediments represent an ongoing threat to the health of aquatic ecosystems. The assessment of sediment quality is, therefore, an important concern for environmental regulators. Sediment quality guidelines are now well established in regulatory frameworks worldwide; however, practical guidance that covers all of the key aspects of sediment quality assessment is not readily available. In 2005, CSIRO published its highly cited Handbook for Sediment Quality Assessment. In the ensuing period, the science has advanced considerably. This practical guide is a revised and much expanded second edition, which will be a valuable tool for environmental practitioners. Written by experts in the field, it provides coverage of: sediment sampling; sample preparation; chemical analysis; ecotoxicology; bioaccumulation; biomarkers; and ecological assessment. In addition, detailed appendices describe protocols for many of the tests to be used.
Extracellular Matrix Remodeling by Nicoletta Gagliano Pdf
The extracellular matrix (ECM) is where cells live. It is composed of collagen and elastic fibers, glycosaminoglycans and proteoglycans, and several glycoproteins. In most tissues, fibril-forming collagen type I is the major constituent of ECM.The function of the ECM goes beyond providing mechanical support to cells and tissues. As cells are embedded into the ECM and interact with its components through their surface receptors, cell–ECM interaction plays a key role in influencing different cell activities, such as cell proliferation and migration. The ECM also sequesters and releases growth factors affecting important cellular pathways. Overall, the ECM strongly influences and affects cell behavior and tissue homeostasis. ECM is a highly dynamic structural network that continuously undergoes controlled remodeling mediated by matrix-degrading enzymes, the matrix metalloproteinases (MMPs), under normal conditions. Quantitative and qualitative deregulation of ECM remodeling and, especially, of collagen turnover, is responsible for the alteration of ECM composition and structure, associated with the development and progression of several pathological conditions, such as organ fibrosis (determined by the abnormal accumulation of ECM components) and tumor invasion. The understanding of the diverse biological roles and properties of the ECM components is pivotal to the development of new therapeutic tools for disease treatment.
Aquatic Physiology, Environmental Pollution, Nanotoxicology and Phytoremediation by Alaa El-Din Hamid Sayed,Francesco Fazio,Tomomi Watanabe-Asaka,Vincenzo Parrino Pdf
This Research Topic is part of the Aquatic Physiology, Environmental Pollution, Nanotoxicology and Phytoremediation series: Aquatic Physiology, Environmental Pollution, Nanotoxicology and Phytoremediation, Volume II Environmental pollution as a result of increasing industrialization is a major problem worldwide. The toxicity of the chemicals, hazards, radiation, and environmental stressor to the aquatic fauna was studied. Although, recently, the excess levels of wastes discharged in water caused severe toxicity in aquatic environments and their fauna, still there is some shortage in the nanotoxicology and phytoremediation studies. So, the aim of this Research Topic is to create some knowledge about the environmental pollution and remediation in aquatic environment in collaboration with experts in physiology, biochemistry, endocrinology, morpho-histology of aquatic fauna. The relation between physiology and other research fields is strong enough as all researchers in biology field use some extent physiological parameters to evaluate the organisms’ health status in normal and stressful conditions. In addition, physiology with endocrinology and neurology can provide a contribution on the endocrine stress response of aquatic vertebrates and regulate the responses of vertebrates to stressors. Whilst the physiology of most aquatic animals has been well studied, not many articles provide sufficient data that helps understanding the common bases of the stress response after exposure to environmental pollutants and mechanisms of action. Such approach needs to be taken both in terms of comparative responses among vertebrates but also among classes or orders within groups of vertebrates. Another aspect that has not been sufficiently approached so far is physiological stress response in relation to immunity, growth, reproduction or behavior and embryology of the aquatic organisms, which expands the knowledge on the interactions between physiological systems to build an overall stress response.
OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay by OECD Pdf
This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...
Fish Physiology: Organic Chemical Toxicology of Fishes by Keith B. Tierney,Anthony Farrell,Colin Brauner Pdf
Fish Physiology: Organic Chemical Toxicology of Fishes discusses the different types of organic chemical contaminants and their respective toxic effects in fish. The book also covers the detection of dissolved organic compounds and methods to assess organic toxicity. Substances addressed in this book include organometallics, hydrocarbons, endocrine disrupting compounds (EDCs), insecticides, herbicides, and pharmaceuticals. Fish are exposed to an ever-increasing array of organic chemicals that find their way into rivers and oceans. Some of these compounds are no longer being produced but nonetheless persist within the environment (persistent organic pollutants, or POPs). The exposure of fish to toxic organic compounds has potential impact on human, fish, and ecosystem health. Yet the regulations that govern environmental water quality vary worldwide, and compliance is never complete. This book provides a crucial resource on these issues for researchers in zoology, fish physiology, and related fields; applied researchers in environmental monitoring, conservation biology, and toxicology; and university-level students and instructors in these areas. Organized by type of toxic organic chemicals Includes metals, POPs, EDCs, herbicides, insecticides, and pharmaceuticals Measures toxicity in a variety of ways aside from lethality Probes the toxic effects of compound mixtures as well as single pollutants
The Fish Oocyte by Patrick J. Babin,Joan Cerdà,Esther Lubzens Pdf
This book addresses the growing needs in deciphering the biological processes associated with fish reproduction, in view of the growth of aquaculture and the dwindling natural stocks of commercially important fish. It presents a comprehensive overview on egg production in fish, from the standpoint of the oocyte. With this view in mind, the book includes chapters on oocyte development (oogenesis), hormonal regulation and hormone receptors, formation of the egg envelopes, growth, accumulation of nutrients and maternal transcripts, maturation, hydration, ovulation and fertilization. A special emphasis is placed on using state-of-the-art tools including electron microscopy for discerning the ultra-structure of the follicle and genomic/proteomic tools to fully understand biological basis of fish reproduction. Studies on promoting oocyte maturation, ovulation and spawning in farmed fish and preservation of fish oocytes at low temperatures are also included. The book will appeal to University lecturers, students, research scientists and those associated with culture of fish in freshwater or marine aquaculture.
Freshwater Microplastics by Martin Wagner,Scott Lambert Pdf
This book is open access under a CC BY 4.0 license. This volume focuses on microscopic plastic debris, also referred to as microplastics, which have been detected in aquatic environments around the globe and have accordingly raised serious concerns. The book explores whether microplastics represent emerging contaminants in freshwater systems, an area that remains underrepresented to date. Given the complexity of the issue, the book covers the current state-of-research on microplastics in rivers and lakes, including analytical aspects, environmental concentrations and sources, modelling approaches, interactions with biota, and ecological implications. To provide a broader perspective, the book also discusses lessons learned from nanomaterials and the implications of plastic debris for regulation, politics, economy, and society. In a research field that is rapidly evolving, it offers a solid overview for environmental chemists, engineers, and toxicologists, as well as water managers and policy-makers.
Tools and Techniques in Biomolecular Science by Aysha Divan,Janice Royds Pdf
This book reviews the theoretical concepts and experimental details underpinning the broad range of modern technologies that are currently being used to advance our understanding of the biomolecular sciences.
