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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on hormone and transport systems. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels
Recent Advances in Understanding Plant Hormone Transporters by Markus Geisler Pdf
Since the first postulation of auxin function by the Darwins, many other plant hormones have been identified and most of them have been found to be synthesized at different sites from their places of action. Hormone transport and thus the responsible hormone transporters are therefore essential for a precise regulation of plant hormone action, which has been repeatedly supported by severe developmental and physiological phenotypes reported for hormone transporter loss-of-function mutants. Plant transporters have been shown to be involved in short and long-distance transport of hormones. Short-distance transport between cells seems to be sufficient for a local hormone action in some tissues (such as seeds), which seem to require exporter and importer proteins in adjacent cells as shown for example for abscisic acid. During long distance transport with the transpiration stream or in the phloem, demonstrated for many (but not all) plant hormones (including auxins, abscisic acid, cytokinins, gibberelins, strigolactones, and salicylic acid), transporters are thought to function in loading and unloading processes. Similarly, in cases where long-distance transport is achieved by cell-to-cell transport (such as for auxins), the highly coordinated action of import and export transporters at the contact surfaces of neighboring cells is apparently needed, however, all these processes are far from being understood on the molecular level. Currently, it appears that many hormones are transported by members of distinct transporter classes, ranging from primary active pumps (that couple hormone translocation to direct ATP hydrolysis), antiporters and symporters (that use the proton motive force to create hormone concentration gradients), and to facilitators. Among those, the ATP-binding cassette (ABC) family and the Nitrate transport1/ Peptide transporter family (NPF) seem to be dominant but currently it is unclear how individual transporters cooperate to achieve a systemic level of transport. Furthermore, in most cases several pairs of importers and exporters are required but how these are correct allocated in order to guarantee the function of a complex hormonal network is unknown. While remarkable progress has been made on hormone transporter regulation on the transcription and post-transcriptional level for transporters involved in long-distance transport (such as auxin), regulation of transporter trafficking, stability and activity is less understood for other hormones.
Regulation of Tissue Oxygenation, Second Edition by Roland N. Pittman Pdf
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Biochemical Actions of Hormones by Gerald Litwack Pdf
Biochemical Actions of Hormones, Volume I explores the significant developments toward understanding the primary effects of hormones in cellular receptors at the molecular level. This book is composed of 12 chapters that survey the molecular and biochemical approaches bearing on the problem of hormone mechanism. The opening chapters discuss the thyroid hormonal responses during metamorphic process in Amphibia; the primary role of hormones in biochemical differentiation; the influence of hormones on protein synthesis and the importance of protein synthesis mechanism; and the biochemical rhythms within the pineal gland and the rhythm in hepatic tyrosine transaminase activity. The subsequent chapters examine the effects of a number of hormones on transport systems in the cell membranes, the protein interaction with steroids, and the influence of insulin on protein and nucleic acid metabolism. The remaining five chapters deal with the physiology, mechanism of action, and biological effects of various hormones, such as mineralocorticoids, parathyroid hormone, calcitonin, thyrotropin, and plant hormones. This book is an invaluable source for endocrinologists.
Author : Peter Hedden,Stephen G. Thomas Publisher : John Wiley & Sons Page : 368 pages File Size : 44,8 Mb Release : 2008-04-15 Category : Science ISBN : 9781405173063
Annual Plant Reviews, Plant Hormone Signaling by Peter Hedden,Stephen G. Thomas Pdf
Plant growth is regulated by developmental programmes that can be modified by environmental cues acting through endogenous signaling molecules including plant hormones. This volume provides an overview of the biosynthesis, catabolism, perception and signal transduction of the individual hormone classes, followed by chapters on hormone distribution and transport, and the roles of hormone signaling in specific developmental processes. Particular attention is paid to the regulation of hormone signaling by environmental and developmental cues, sites of hormone metabolism and action, and interactions between hormone signaling pathways. The book is directed at researchers and professionals in plant biochemistry and molecular biology.
Hormonal Regulation of Development II by T.K. Scott Pdf
This is the second of the set of three volumes in the Encyclopedia of Plant Physiology, New Series, that will cover the area of the hormonal regulation of plant growth and development. The overall plan for the set assumes that this area of plant physiology is sufficiently mature for a review of current knowl edge to be organized in terms of unifying principles and processes. Reviews in the past have generally treated each class of hormone individually, but this set of volumes is subdivided according to the properties common to all classes. Such an organization permits the examination of the hypothesis that differing classes of hormones, acting according to common principles, are determinants of processes and phases in plant development. Also in keeping with this theme, a plant hormone is defined as a compound with the properties held in common by the native members of the recognized classes of hormone. Current knowledge of the hormonal regulation of plant development is grouped so that the three volumes consider advancing levels of organizational complexity, viz: molecular and subcellular; cells, tissues, organs, and the plant as an organized whole; and the plant in relation to its environment.
Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics. Presents the latest information on thyroid hormone Provides a long-running series that focuses on updates and advances in vitamins and hormones Covers single molecules or diseases that are related to vitamins or hormones, with the topic broadly interpreted to include related substances
Mammalian Amino Acid Transport by D. Häussinger,M.S. Kilberg Pdf
Amino acid transport is a part of each of two larger subjects, amino acid metabolism and the biomembrane transport of various . small molecules and ions. Nevertheless in this volume we treat amino acid transport as more than a fragment of either of these two larger subjects. A more comprehensive approach is justified when we remember two historic and ongoing aspects of the title subject. First, amino acid transport had its beginning and acquired a distinct momentum (even if somewhat interrupted from 1913 until about 1945) as amino acid metabolism with the central and pioneer work of Van Slyke and Meyer in 1913. The reviews in this volume will show that it steadily becomes a larger aspect of amino acid metabolism, broadly perceived. These chapters will show for how many organelles, cells, tissues, organs and organ systems, the transmembrane compartmentations and flows of amino acids play very large parts in their fundamental biological relations. The authors here are tending collectively to evaluate an understanding of amino acid flows across biomernbranes, and the regulation of these flows, as necessary to an ultimate understanding of the full range of development and metabolism. Such an understanding goes far beyond the purely substrate-destabilizing contributions by enzymes, which have often been arbitrarily limited to that conceptual entity, "the cell", and which for so long a splendid time had most of biochemical research attention.
Human Biochemistry includes clinical case studies and applications that are useful to medical, dentistry and pharmacy students. It enables users to practice for future careers as both clinicians and researchers. Offering immediate application of biochemical principles into clinical terms in an updated way, this book is the unparalleled textbook for medical biochemistry courses in medical, dental and pharmacy programs. Winner of a 2018 Most Promising New Textbook (College) Award (Texty) from the Textbook and Academic Authors Association Offers immediate application of biochemical principles into clinical terms in an updated way Contains coverage of the most current research in medical biochemistry Presents the first solution designed to reflect the needs of both research oriented and clinically oriented medical students
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on hormones of the limbic system. Longest running series published by Academic Press Contributions by leading international authorities
Clinical Management of Thyroid Disease E-Book by Fredric E. Wondisford,Sally Radovick Pdf
Clinical Management of Thyroid Disease is an exciting new book edited by Fredric Wondisford, MD—developer of the revolutionary new drug, Thyrotropin—and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format. Presents the expertise of authors and editorial staff comprised of leaders in the field of thyroid research and clinical management for the best-qualified guidance on diagnosis and treatment. Provides a full-color, comprehensive approach that makes valuable information easy to locate and quick to read. Covers relevant topics applicable to all levels of training and expertise to serve as a detailed clinical reference on everything from the basic to the sophisticated. Captures research advances on hot topics such as thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, and genetic disorders so that you can incorporate them into the way you treat patients.