Hpv Infection In Head And Neck Cancer

Author : Wojciech Golusiński,C. René Leemans,Andreas Dietz
Publisher : Springer
Page : 257 pages
File Size : 47,6 Mb
Release : 2016-10-03
Category : Medical
ISBN : 9783319435800

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HPV Infection in Head and Neck Cancer by Wojciech Golusiński,C. René Leemans,Andreas Dietz Pdf

This book is exceptional in presenting an interdisciplinary approach to the subject of human papillomavirus (HPV) infection in the context of head and neck cancer. Leading experts in the field discuss the epidemiology and molecular biology of HPV-positive head and neck squamous cell carcinoma, HPV testing, the nonsurgical and surgical treatment of HPV-positive tumors, predictive factors for outcome and quality of life, and ongoing trials on the effectiveness of vaccination in disease prevention. It also provides recommendations for testing, diagnosis treatment and vaccination. Otolaryngologists, head and neck surgeons, medical oncologists, radiation oncologists, molecular biologists and pathologists will find this book a valuable resource.

Author : Carole Fakhry,Gypsyamber D’Souza
Publisher : Springer
Page : 127 pages
File Size : 47,6 Mb
Release : 2015-07-11
Category : Medical
ISBN : 9788132224136

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HPV and Head and Neck Cancers by Carole Fakhry,Gypsyamber D’Souza Pdf

This book serves a snapshot of the current knowledge base in field. As human papillomavirus (HPV) causes a rising number of oropharyngeal cancers, understanding the biological, clinical and social implications of this infection has become increasingly important for head and neck practitioners. This book reflects the multidisciplinary nature of the scientific and clinical questions involved in this disease. Experts in epidemiology, diagnosis and treatment of HPV-related oropharyngeal cancer present in-depth reviews which will help to improve the reader’s understanding of this topic. The authors provide insight for answers of common patient and provider questions about HPV infection and related disease, and highlight remaining questions to be answered in the coming years.

Author : Daniel L. Miller,M. Sharon Stack
Publisher : Springer
Page : 314 pages
File Size : 47,5 Mb
Release : 2015-08-01
Category : Medical
ISBN : 9783319211008

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Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer by Daniel L. Miller,M. Sharon Stack Pdf

Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overall incidence of HNSCC has decreased in recent years in many countries. In contrast, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased significantly, and this subtype of HNSCC is commonly associated with human papillomavirus (HPV) infection. Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity. This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches. Chapters are contributed by authoritative leaders in the fields of research and clinical care. Initial chapters address epidemiology, behavioral correlates of HPV infection, and racial disparities in oropharyngeal cancer. This is followed by chapters detailing HPV virology with focus on viral transformation, viral replication, and host response to viral infection. The molecular biology of HPV-associated OPSCC is investigated in chapters detailing alterations in signaling networks and unique mutational profiles of human tumors. Clinical presentation, surgical perspectives, and treatment paradigms specific to HPV-associated OPSCC conclude the volume. This comprehensive volume provides an up-to-date overview of both scientific discovery and clinical management of this emerging public health problem.

Author : Sara I Pai
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 55,9 Mb
Release : 2012-07-29
Category : Medical
ISBN : 9781455747450

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HPV and Head and Neck Cancer, An Issue of Otolaryngologic Clinics - E-Book by Sara I Pai Pdf

HPV is a growing epidemic in head and neck cancer and specialists working with these diseases are provided information on shifting trends in HPV in head and neck cancers along with challenges and controversies in treating this disease. With this virus related cancer, there is a different approach to managing this patient population. Novel therapeutic treatments are actively being developed for this type of head and neck cancer. Topics include: Epidemioloygy of HPV-head and neck cancer; Clinical detection of HPV; Clinical evaluation and disease patterns of HPV-related head and neck cancers; Impact of HPV-related head and neck cancer in clinical trials; Molecular biology of HPV and head and neck cancer and targeted therapies; Transoral robotic surgery: new surgical techniques for oropharyngeal cancers; Economic impact of HPV-related cancers; Rehabilitation needs of oropharyngeal cancer patients; Psychosocial care needs of HPV-head and neck cancer patients; and a Multi-disciplinary approach to head and neck cancers.

Author : Jerome R. Lechien,Stéphane Hans,Francois Mouawad
Publisher : Frontiers Media SA
Page : 160 pages
File Size : 52,7 Mb
Release : 2022-03-25
Category : Medical
ISBN : 9782889747559

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Advances in the Involvement of Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma by Jerome R. Lechien,Stéphane Hans,Francois Mouawad Pdf

Author : James A. Radosevich
Publisher : Springer Science & Business Media
Page : 198 pages
File Size : 42,9 Mb
Release : 2012-12-14
Category : Medical
ISBN : 9789400754379

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HPV and Cancer by James A. Radosevich Pdf

“HPV and Cancer” is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes. We then look at the dynamic trends of this infectious agent in the human population, how it interacts with human cells, and the role it plays with other organisms to produce both benign and malignant tumors. Lastly, there is a discussion about a new vaccine for HPV and the hopes that are held by many to change the trends with this virus and the associated cancers it produces.

Author : Alison A. McBride,Karl Munger
Publisher : MDPI
Page : 385 pages
File Size : 51,9 Mb
Release : 2018-05-04
Category : Electronic books
ISBN : 9783038428374

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Expert Views on HPV Infection by Alison A. McBride,Karl Munger Pdf

This book is a printed edition of the Special Issue "Expert Views on HPV Infection" that was published in Viruses

Author : Norhafiza Mat Lazim
Publisher : Bentham Science Publishers
Page : 352 pages
File Size : 41,9 Mb
Release : 2021-03-31
Category : Medical
ISBN : 9789811803222

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Head and Neck Cancer: Hallmarks of the Inflammation Ecosystem by Norhafiza Mat Lazim Pdf

This reference comprehensively covers the clinical aspects of head and neck neoplasms while also highlighting the relationship that exists between inflammation and these cancers. This relationship is critical as it dictates the risks, assessment, treatment, and prognosis of head and neck cancer patients. The book starts with an introduction to the inflammation ecosystem in head and neck malignancy, followed by detailed discussions on the types of head and neck malignancy and their histological classification. The book then provides information about specialized topics relevant to the specialty of head and neck oncology. Key Features: - Comprehensive coverage of head and neck cancers with topic-based chapters - Introductory text explaining the basics of inflammation - Detailed information on the relationship between inflammation and head and neck neoplasms - Information about the classification of head and neck cancers - Methods for diagnosis and treatment - Special topics such as complications caused by HPV infections, chemoradiation, immune-targeted therapy, and inflammatory biomarkers - References for further reading The combination of basic and advanced topics makes this book an informative reference for medical students and professionals at all levels. Residents specializing in otolaryngology, oncology, and surgery as well as researchers studying inflammation will also gain an understanding of the subject in relation to oncogenesis.

Author : Kari J. Syrjänen,Stina M. Syrjänen
Publisher : Wiley-Blackwell
Page : 644 pages
File Size : 42,7 Mb
Release : 2000-05-25
Category : Medical
ISBN : UOM:39015042593502

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Papillomavirus Infections in Human Pathology by Kari J. Syrjänen,Stina M. Syrjänen Pdf

This is the most up-to-date and comprehensive reference source on papillomavirus-associated human pathology, which examines the molecular biology of the infections and discusses diagnosis and treatment methods. Abundantly illustrated, it covers all aspects of human papillomaviruses from molecular biology and pathogenesis of HPV-associated diseases, as well as natural history and epidemiology, to a detailed study of the role of these viruses as potential etiological agents of a wide spectrum of both benign and malignant human tumours. While the main focus is on HPV infections of the genital tract, lesions of the skin, respiratory tract, the digestive system, the urinary tract and the eye are also covered in detail. Written by two authors who are internationally renowned for their work, it will be invaluable for both clinicians and researchers working in the fields of gynecology, pathology, sexually transmitted diseases, genito-urinary medicine, oncology, dermatology, otorhinolaryngology, and cancer epidemiology.

Author : Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Publisher : Unknown
Page : 392 pages
File Size : 55,5 Mb
Release : 2006
Category : Immunization
ISBN : 0660193922

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Canadian Immunization Guide by Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization Pdf

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Author : Barbara Burtness,Erica A. Golemis
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 47,9 Mb
Release : 2014-04-08
Category : Medical
ISBN : 9781461488156

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Molecular Determinants of Head and Neck Cancer by Barbara Burtness,Erica A. Golemis Pdf

Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. In the past several years, there have been significant developments in understanding of HNC. It is now recognized that although alcohol and tobacco use has represented the likely predominant cause of SCCHN, the incidence of a second class of SCCHN related to oncogenic human papillomavirus (HPV) infection is increasing, with a four-fold increase in the past 2 decades, and now thought to represent up to 30% of cases. The first effective target for SCCHN, the EGFR-targeting antibody cetuximab, was approved as recently as in 2006; since then, a growing body of research has identified additional signaling pathways as important in disease pathogenesis, and in resistance to treatment. Proteins such as c-Met, Src, and HER2 are emerging as new therapeutic targets, with a considerable ferment in the clinical trial community. As a capstone of research progress, 2011 marked the first reports of high throughput sequencing of SCCHN tumors, with these efforts identifying unexpected players such as Notch as frequent subject of mutation, spawning new hypotheses for future research. This book will be of interest to researchers who are interested in better understanding the biology of head and neck cancers, with the goals of better designing therapies, identifying risk factors, or investigating the molecular basis of the disease.

Author : Heather Walline
Publisher : Mdpi AG
Page : 0 pages
File Size : 42,6 Mb
Release : 2023-02-08
Category : Electronic
ISBN : 3036567054

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Human Papillomavirus and Head and Neck Cancer by Heather Walline Pdf

In the study of head and neck squamous cell carcinoma (HNSCC), we know that virally induced malignancies behave differently than those generated through other carcinogenic mechanisms. This paradigm extends into differences in tumor growth, treatment response and resistance, as well as invasion and metastasis. The inability to correctly diagnose and appropriately treat HNSCC at early stages has contributed to reduced survival for HNSCC patients, particularly those with HPV-negative disease. The examination of the molecular differences between HPV-positive and HPV-negative HNSCC will provide support for early diagnostic markers and guide appropriate treatment selection to improve patient care and survival. This Special Issue highlights current research efforts to understand the evolving contribution of human papillomavirus in HNSCC.

Author : Gerd Gross,Stephen K. Tyring
Publisher : Springer Science & Business Media
Page : 925 pages
File Size : 49,9 Mb
Release : 2011-08-19
Category : Medical
ISBN : 3642146635

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Sexually Transmitted Infections and Sexually Transmitted Diseases by Gerd Gross,Stephen K. Tyring Pdf

This comprehensive, up-to-date reference book is intended to serve as the standard guide in the field. It covers the epidemiology and etiology of the various sexually transmitted infections and associated diseases, reviews novel diagnostic methods, and discusses in depth both new and established treatment methods. An important part of the book is devoted to prevention and particularly to immunoprevention by vaccination. Related issues such as sexual abuse, psychosocial aspects, and economic and political considerations are also included. The expertise of many worldwide renowned specialists and superb color illustrations make this book a valuable resource for practitioners from a variety of medical disciplines. It has a reader-friendly structure with “core messages” and “take-home pearls”.

Author : Jan B. Vermorken,Volker Budach,C. René Leemans,Jean-Pascal Machiels,Piero Nicolai,Brian O'Sullivan
Publisher : Springer Nature
Page : 361 pages
File Size : 50,6 Mb
Release : 2023-03-27
Category : Medical
ISBN : 9783031231759

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Critical Issues in Head and Neck Oncology by Jan B. Vermorken,Volker Budach,C. René Leemans,Jean-Pascal Machiels,Piero Nicolai,Brian O'Sullivan Pdf

This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.

Author : M.K. Ramírez-Fort,F. Khan,P.L. Rady,S.K. Tyring
Publisher : Karger Medical and Scientific Publishers
Page : 282 pages
File Size : 46,8 Mb
Release : 2014-03-13
Category : Medical
ISBN : 9783318025279

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Human Papillomavirus by M.K. Ramírez-Fort,F. Khan,P.L. Rady,S.K. Tyring Pdf

Human papillomavirus (HPV) infection transcends multiple fields of science and medicine. The management of HPV-related disease is demanding and often requires a persistent multimodal approach involving various medical disciplines. In this volume, experts present a comprehensive view of HPV research with an emphasis on clinical presentations, diagnosis, management and vaccine development. The state of the art in molecular biology is provided in addition to discussions on clinical morphology and the utility of dermatoscopy in identifying HPV disease. In a multidisciplinary approach to dermatological, plastic and reconstructive, gynecological, otolaryngological and colorectal management, different treatment strategies are highlighted. Finally, Dr. Neil Christensen discusses viral immunology, and the difficulties and successes in the development of an HPV vaccine. Bringing together basic science and clinical information on HPV, this book is an excellent resource and reference for all researchers and clinicians who encounter human papillomavirus-related disease.