Production Of Plasma Proteins For Therapeutic Use

Author : Joseph Bertolini,Neil Goss,John Curling
Publisher : John Wiley & Sons
Page : 518 pages
File Size : 44,6 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9780470924310

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Production of Plasma Proteins for Therapeutic Use by Joseph Bertolini,Neil Goss,John Curling Pdf

Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.

Author : Bertolini
Publisher : Unknown
Page : 500 pages
File Size : 41,8 Mb
Release : 2020-04-22
Category : Electronic
ISBN : 1119542502

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Production of Plasma Proteins for Therapeutic Use, 2nd Edition by Bertolini Pdf

Author : José Luis Valverde
Publisher : IOS Press
Page : 338 pages
File Size : 41,9 Mb
Release : 2006
Category : Business & Economics
ISBN : 1586036017

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Blood, Plasma, and Plasma Proteins by José Luis Valverde Pdf

Labile blood products and plasma-derived products are very sensitive form a social viewpoint. Along with the challenges faced by all medicinal products there is an added challenge due to the lack of raw material and the social problems with regards to their acquisition. Obtaining them depends on blood and plasma donations, which are insufficient. Europeans as a whole fail to even cover 40 % of their needs in plasma for fractionation. The aspiration that all donations shall be voluntary, free and unpaid, is an altruistic objective, which reality, unfortunately, contradicts every day. Governments and all social Agencies should promote to the maximum its actions in order to achieve the greatest number of donation each day. Even from a humanitarian or ethical viewpoint nobody can deny a possible donor accepting incentives. This incentive discussion, plus the concept of self-sufficiency of countries and more are discussed in this volume.

Author : Toby L. Simon,Jeffrey McCullough,Edward L. Snyder,Bjarte G. Solheim,Ronald G. Strauss
Publisher : John Wiley & Sons
Page : 754 pages
File Size : 48,8 Mb
Release : 2016-05-23
Category : Medical
ISBN : 9781119012993

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Rossi's Principles of Transfusion Medicine by Toby L. Simon,Jeffrey McCullough,Edward L. Snyder,Bjarte G. Solheim,Ronald G. Strauss Pdf

Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available Led by a world class Editor team, including two past-presidents of AABB, a past- President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee , and international contributor team Comprehensive reference resource, considered the gold standard in transfusion Covers current hot topics such as donor care – including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, cstem cell therapies, and global aspects of the organization of transfusion and transplant services New material on molecular immunohematology Companion website includes figures, full text and references

Author : John Sylvester Finlayson,David L. Aronson
Publisher : Unknown
Page : 88 pages
File Size : 42,8 Mb
Release : 1980
Category : Blood proteins
ISBN : LCCN:80136227

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Therapeutic Use of Plasma Proteins by John Sylvester Finlayson,David L. Aronson Pdf

Author : Joseph Bertolini,Neil Goss,John Curling
Publisher : John Wiley & Sons
Page : 518 pages
File Size : 42,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781118356791

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Production of Plasma Proteins for Therapeutic Use by Joseph Bertolini,Neil Goss,John Curling Pdf

Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.

Author : Theodore Peters Jr.
Publisher : Academic Press
Page : 455 pages
File Size : 50,7 Mb
Release : 1995-12-21
Category : Science
ISBN : 9780080527048

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All About Albumin by Theodore Peters Jr. Pdf

The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. Includes up-to-date sequences, structures, and compositions of many species Reviews the protein chemistry, genetic control, and metabolism of albumin Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory Presents the relationship of albumin to its superfamily with an updated scheme for their evolution First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references

Author : Hubert Peeters,Peter H. Wright
Publisher : Pergamon
Page : 84 pages
File Size : 44,7 Mb
Release : 1979
Category : Blood proteins
ISBN : UOM:39015057723176

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Plasma Protein Pathology by Hubert Peeters,Peter H. Wright Pdf

Author : Christopher V. Prowse
Publisher : Unknown
Page : 248 pages
File Size : 40,5 Mb
Release : 1992-06
Category : Medical
ISBN : UOM:39015022274032

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Plasma and Recombinant Blood Products in Medical Therapy by Christopher V. Prowse Pdf

Provides an introduction to the preparation and therapeutic use of blood products and the potential contribution of molecular biology. Focuses on understanding the molecular mechanisms of human physiology, disease and new medical techniques for clinical diagnosis and treatment.

Author : Varsha Gupta,Manjistha Sengupta,Jaya Prakash,Baishnab Charan Tripathy
Publisher : Springer
Page : 527 pages
File Size : 41,7 Mb
Release : 2016-10-22
Category : Technology & Engineering
ISBN : 9789811008757

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Basic and Applied Aspects of Biotechnology by Varsha Gupta,Manjistha Sengupta,Jaya Prakash,Baishnab Charan Tripathy Pdf

This book explores the journey of biotechnology, searching for new avenues and noting the impressive accomplishments to date. It has harmonious blend of facts, applications and new ideas. Fast-paced biotechnologies are broadly applied and are being continuously explored in areas like the environmental, industrial, agricultural and medical sciences. The sequencing of the human genome has opened new therapeutic opportunities and enriched the field of medical biotechnology while analysis of biomolecules using proteomics and microarray technologies along with the simultaneous discovery and development of new modes of detection are paving the way for ever-faster and more reliable diagnostic methods. Life-saving bio-pharmaceuticals are being churned out at an amazing rate, and the unraveling of biological processes has facilitated drug designing and discovery processes. Advances in regenerative medical technologies (stem cell therapy, tissue engineering, and gene therapy) look extremely promising, transcending the limitations of all existing fields and opening new dimensions for characterizing and combating diseases.

Author : C.Th. Smit Sibinga,P.C. Das,H.T. Meryman
Publisher : Springer Science & Business Media
Page : 297 pages
File Size : 43,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461315155

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Cryopreservation and low temperature biology in blood transfusion by C.Th. Smit Sibinga,P.C. Das,H.T. Meryman Pdf

The theme of this 14th International Symposium on Blood Transfusion is closely related to the work and scientific contributions of the Dutch cryobiology pioneer Dr. Herman W. Krijnen of the Dutch Red Cross Central Laboratory. Dr. Krijnen was known and respected in the national and interna tional blood transfusion community as an extremely competent scientist and a beloved and admired colleague. Dr. Krijnen was intentionally honoured with the invitation to open this symposium on cryopreservation and low temperature biology in blood transfusion and be the guest of honour at this event. Unfortunately, Dr. Krijnen suddenly died on the first of June 1989. In honour and mem ory of Dr. Krijnen this symposium will therefore be dedicated to him. Since the lOth International Symposium on Blood Transfusion in 1985 highlighted the theme of "Future developments in blood banking", major changes have occurred in the blood banking world. Most of these changes were forced upon the Blood Banks by the fear of spreading AIDS through contaminated donations. This not only led to the wide spread testing of blood, but also to a more appropriate counselling of the community and the blood donors in specific. Additionally, virus inacti vation techniques were introduced for those components derived from multiple donations and intended for a regular transfusion in haemophi lia patients and others.

Author : Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel
Publisher : John Wiley & Sons
Page : 538 pages
File Size : 49,5 Mb
Release : 2008-05-23
Category : Science
ISBN : 0470724366

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Human Blood Plasma Proteins by Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel Pdf

Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

Author : Chibuike C. Udenigwe
Publisher : Royal Society of Chemistry
Page : 537 pages
File Size : 55,8 Mb
Release : 2021-06-09
Category : Science
ISBN : 9781788018593

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Food Proteins and Peptides: Emerging Biofunctions, Food and Biomaterial Applications by Chibuike C. Udenigwe Pdf

This book discusses the chemistry of food proteins and peptides and their relationship with nutritional, functional, and health applications. Bringing together authorities in the field, it provides a comprehensive discussion focused on fundamental chemistries and mechanisms underpinning the structure-function relationships of food proteins and peptides. The functional and bioactive properties hinge on their structural features such as amino acid sequence, molecular size, hydrophobicity, hydrophilicity, and net charges. The book includes coverage of advances in the nutritional and health applications of protein and peptide modifications; novel applications of food proteins and peptides in the development of edible functional biomaterials; advances in the use of proteomics and peptidomics for food proteins and peptide analysis (foodomics); and the relevance of food protein and peptide chemistries in policy and regulation. Research into the fundamental chemistries behind the functional, health and nutritional benefits is burgeoning and has gained the interest of scientists, the industry, regulatory agencies, and consumers. This book fills the knowledge gap providing an excellent source of information for researchers, instructors, students, food and nutrition industry, and policy makers.

Author : H.-J. Gurland,V. Heinze,H.A. Lee
Publisher : Springer Science & Business Media
Page : 238 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642679568

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Therapeutic Plasma Exchange by H.-J. Gurland,V. Heinze,H.A. Lee Pdf

This volume contains papers and discussions of the Vlth Dialyse-Arzte Workshop, which was held in Bernried at Lake Starnberg near Munich the 5th and 6th of March 1980. Generous ly sponsored by Travenol, Munich, the Dialyse-Arzte meetings now have a tradition spanning 16 years. According to the con stitution of these meetings, the topics of earlier years had to cover dialysis and related fields. Thus the sponsor requested that this year also one lecture - incorporated here as part - should deal with the state of art of dialysis, thereby hopefully linking this Workshop to the previous meetings. Dialysis techniques of the 1960s, pioneered by many of attend ing speakers and panelists (see List of Contributors), have never come to a standstill. Indeed, vascular access and extra corporeal circulation have become routine for the nephrologist and have made possible the introductimn of new approaches, such as hemofiltration and hemoperfusion. Also today new membrane technologies provide us with a potentially even more effective therapeutic tool, namely plasma separation.

Author : Allison R. Kermode
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 42,6 Mb
Release : 2018-03-12
Category : Science
ISBN : 9781118801482

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Molecular Pharming by Allison R. Kermode Pdf

A single volume collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins This comprehensive book communicates the recent advances and exciting potential for the expanding area of plant biotechnology and is divided into six sections. The first three sections look at the current status of the field, and advances in plant platforms and strategies for improving yields, downstream processing, and controlling post-translational modifications of plant-made recombinant proteins. Section four reviews high-value industrial and pharmacological proteins that are successfully being produced in established and emerging plant platforms. The fifth section looks at regulatory challenges facing the expansion of the field. The final section turns its focus toward small molecule therapeutics, drug screening, plant specialized metabolites, and plants as model organisms to study human disease processes. Molecular Pharming: Applications, Challenges and Emerging Areas offers in-depth coverage of molecular biology of plant expression systems and manipulation of glycosylation processes in plants; plant platforms, subcellular targeting, recovery, and downstream processing; plant-derived protein pharmaceuticals and case studies; regulatory issues; and emerging areas. It is a valuable resource for researchers that are in the field of plant molecular pharming, as well as for those conducting basic research in gene expression, protein quality control, and other subjects relevant to molecular and cellular biology. Broad ranging coverage of a key area of plant biotechnology Describes efforts to produce pharmaceutical and industrial proteins in plants Provides reviews of recent advances and technology breakthroughs Assesses realities of regulatory and cost hurdles Forward looking with coverage of small molecule technologies and the use of plants as models of human disease processes Providing wide-ranging and unique coverage, Molecular Pharming: Applications, Challenges and Emerging Areas will be of great interest to the plant science, plant biotechnology, protein science, and pharmacological communities.