Ia Antigens

Author : David Ferrone
Publisher : CRC Press
Page : 173 pages
File Size : 54,9 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351081771

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Ia Antigens by David Ferrone Pdf

The purpose of this book is to provide the reader with a ready source of information regarding Ia antigens in several animal species.The significance role played by the gene products of I regions in cell-cell interactions has stimulated interest in the characterization of Ia antigens. Through the effort of several investigations much information about the functional and structural properties of Ia antigens has been accumulated in recent years.

Author : Hugh Mcdevitt
Publisher : Elsevier
Page : 632 pages
File Size : 43,7 Mb
Release : 2012-12-02
Category : Nature
ISBN : 9780323144216

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Ir Genes and Ia Antigens by Hugh Mcdevitt Pdf

Ir Genes and Ia Antigens features papers that were presented at the Third Ir Gene Workshop held in Asilomar, California, December 13-16, 1976. The book is organized into seven parts that correspond to the seven sessions held during the workshop. The first session focused on the definition of the I-E and I-C subregions, and the mapping and cellular expression of complementing Ir genes. The second session included papers on the expression of gene products of the I region. The third session covered two major areas: (1) the biochemical characterization and primary structure of la antigens; and (2) the possible carbohydrate nature of la antigenic determinant. The studies presented in the fourth session focused on the role of I-region gene products in cellular interactions. The fifth session discussed the "recognition" functions controlled by the I region of the major histocompatibility complex (MHC). The sixth session featured papers on la-containing T cell factors. Finally, the seventh session examined the properties of T-cell antigen receptors.

Author : David Ferrone
Publisher : CRC Press
Page : 554 pages
File Size : 47,8 Mb
Release : 2019-07-23
Category : Medical
ISBN : 9781351090230

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Ia Antigens by David Ferrone Pdf

The purpose of this book is to provide the reader with a ready source of information regarding Ia antigens in several animal species.The significance role played by the gene products of I regions in cell-cell interactions has stimulated interest in the characterization of Ia antigens. Through the effort of several investigations much information about the functional and structural properties of Ia antigens has been accumulated in recent years.

Author : Anonim
Publisher : Unknown
Page : 184 pages
File Size : 52,9 Mb
Release : 1982
Category : Ia antigens
ISBN : UOM:39015001637035

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Ia Antigens: Man and other species by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 322 pages
File Size : 43,7 Mb
Release : 1976
Category : Antigens
ISBN : 8716022548

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Biochemistry and Biology of Ia Antigens by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 274 pages
File Size : 44,6 Mb
Release : 1982
Category : Ia antigens
ISBN : UOM:39015001637027

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Ia Antigens: Mice by Anonim Pdf

Author : J. Brochier,J. Clot,Jacques Sany
Publisher : Unknown
Page : 176 pages
File Size : 49,7 Mb
Release : 1986
Category : Autoimmune diseases
ISBN : UCAL:B5041151

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Anti-Ia Antibodies in the Treatment of Autoimmune Disease by J. Brochier,J. Clot,Jacques Sany Pdf

Author : Ellen Sung
Publisher : Unknown
Page : 326 pages
File Size : 55,6 Mb
Release : 1982
Category : Ia antigens
ISBN : STANFORD:36105025677910

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The Structure and Biosynthesis of the Ia Antigens and Their Associated Invariant Chain by Ellen Sung Pdf

Author : Carl W. Pierce,Susan E. Cullen,Judith A. Kapp,Benjamin D. Schwartz,Donald C. Shreffler
Publisher : Springer Science & Business Media
Page : 574 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461256335

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Ir Genes by Carl W. Pierce,Susan E. Cullen,Judith A. Kapp,Benjamin D. Schwartz,Donald C. Shreffler Pdf

The Fifth Ir Gene Workshop was held at the Chase-Park Plaza Hotel, St. Louis, MO, August 28-31, 1982; 240 scientists participated in the Workshop. The man uscripts compiled in this book describe the state of the art concerning Ir genes. Although the notion of Ir Genes: Past, Present, and Future has not been ad dressed specifically by each author, the reader is certain to get this flavor from the contributions. In this Preface, we have tried to summarize some of the salient ob servations and discussions from the Workshop. The mUltiple genes of the I region have been defined traditionally by serolog ical analysis of intra-H-2 recombinant mice and the pattern of immune responses to certain antigens developed by these recombinant mice. The application of sev eral new techniques, such as gene cloning and DNA sequencing, production of T and B cell hybridomas, and development of cloned T cell lines has changed this tradition and introduced a new phase into the analysis of the I region, Ia antigens, and Ir genes.

Author : B. Parham
Publisher : Springer Science & Business Media
Page : 250 pages
File Size : 55,6 Mb
Release : 2013-03-09
Category : Science
ISBN : 9789400958944

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Histocompatibility Antigens by B. Parham Pdf

The Major Histocompatibility Complex (MHC) was discovered as a con sequence of the chronic problem encountered by cancer biologists in the early years of this century: the failure to maintain tumor lines by serial passage in outbred mice. A number of observations pointed to genetic similarity being a prerequisite for successful transplantation and they were incorporated into a genetic theory of transplantation by C.C. Little. This prompted scientists like Little to initiate breeding experiments designed to test his hypothesis and produce genetically identical mice which would permit the growth of trans planted tumors. Most inbred strains of mice commonly used in immunology derive from those efforts. Transplantation of normal tissues obeyed the same rules found for malignant tissues and rejection was shown to be an immunological phenomenon. G.D. Snell showed that a single genetic locus determined rapid rejection of skin grafts. This was initially called the Major Histocompatibility Locus but was subsequently shown to include many functionally related genes and renamed the Major Histocompatibility Complex (MHC). In mouse this is the H-2 complex and man the HLA complex. During this same period P.A.

Author : Michael Sela,Norman Arnheim
Publisher : Unknown
Page : 368 pages
File Size : 41,8 Mb
Release : 1973
Category : Medical
ISBN : PSU:000013713942

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The Antigens by Michael Sela,Norman Arnheim Pdf

Author : Michael Sela
Publisher : Academic Press
Page : 368 pages
File Size : 54,6 Mb
Release : 2014-05-10
Category : Science
ISBN : 9781483269665

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The Antigens by Michael Sela Pdf

The Antigens, Volume VII is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Different aspects of the genetic control of the immune response are explored, along with the link between infection and autoimmunity. Comprised of four chapters, this volume begins with a discussion on the determinant-specific genetic regulation of the immune response and the genes that control it. The next chapter deals with the molecular genetics and polymorphism of of class II (Ia) antigens, as well as the correlation between immunogenetic and molecular genetic maps. The antigen-specific T cell clones and the specific factors derived from them are then examined. The last chapter considers the relationship between infection and autoimmunity; the role of infection in the expression of class II antigens; and processes responsible for the induction of autoimmune diseases. A specific therapy for these diseases is described. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

Author : C. David
Publisher : Springer
Page : 850 pages
File Size : 43,8 Mb
Release : 2014-11-14
Category : Medical
ISBN : 9781475707649

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H-2 Antigens by C. David Pdf

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 44,7 Mb
Release : 2024-06-02
Category : Electronic
ISBN : OCLC:1403466867

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Ia Antigens by Anonim Pdf

Author : Bjarte G. Solheim,Erna Moller,Soldano Ferrone
Publisher : Springer Science & Business Media
Page : 564 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642703676

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HLA Class II Antigens by Bjarte G. Solheim,Erna Moller,Soldano Ferrone Pdf

This volume deals with the structure and function of molecules that have, during the last decade, turned out to have a central role in immune responses. Trans plantation antigens were discovered and characterized by Gorer about 50 years ago, and the biological basis for the unequalled complexity of their variability between individuals within a species, in spite of extreme conservation between species, was the subject of intense research and discussion for many years. During the days of belief in "immune surveillance" against spontaneously developing tumors, it was suggested that histoincompatibility between members of one species would prevent cancer from being a contagious disease and thus a threat to the species. Immunologists involved in human transplantation had to learn and care about the complexity, especially after 1967, when it was found that HLA antigens were the products of the human MHC. Rejection of HLA-identical sib kidney grafts was so rare, even in those days, that cases of rejection were described in scientific papers.