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Author : Andreas Walter,Julia Gisela Mannheim,Carmel J. Caruana
Publisher : Unknown
Page : 0 pages
File Size : 42,6 Mb
Release : 2021
Category : Electronic
ISBN : OCLC:1421926122
Author : Andreas Walter,Julia G.. Mannheim,Carmel Caruana
Publisher : IOP Publishing Limited
Page : 550 pages
File Size : 41,6 Mb
Release : 2021
Category : Science
ISBN : 0750330570
The relentless pace of innovation in biomedical imaging has provided modern researchers with an unprecedented number of techniques and tools to choose from. While the development of new imaging techniques is vital for ongoing progress in the life sciences, it is challenging for researchers to keep pace. Imaging Modalities for Biological and Preclinical Research is designed to provide a comprehensive overview of currently available biological and preclinical imaging methods, including their benefits and limitations. Experts in the field guide the reader through both the physical principles and biomedical applications of each imaging modality, including description of typical setups and sample preparation. Volume 1 focuses on ex-vivo imaging. It covers all available advanced and basic light and fluorescence microscopy modalities, X-ray, electron, atomic force and helium ion microscopy, dynamic techniques such as fluorescence recovery after photobleaching as well as spectroscopic techniques such as coherent Raman imaging or mass spectrometry imaging. Key features Provides an overview of fast-evolving ex-vivo imaging technologies. Bridges biological and preclinical imaging. Written by imaging specialists with extensive expertise in their respective fields.
Author : Andreas Walter,Julia Mannheim,Carmel J. Caruana
Publisher : Unknown
Page : 128 pages
File Size : 54,5 Mb
Release : 2020
Category : Biomedical engineering
ISBN : 0750330589
Author : Carmel J. Caruana
Publisher : Physics and Engineering in Med
Page : 700 pages
File Size : 48,6 Mb
Release : 2021-05-18
Category : Science
ISBN : 0750337451
The relentless pace of innovation in biomedical imaging has provided modern researchers with an unprecedented number of techniques and tools to choose from. While the development of new imaging techniques is vital for ongoing progress in the life sciences, it is challenging for researchers to keep pace. Imaging Modalities for Biological and Preclinical Research is designed to provide a comprehensive overview of currently available biological and preclinical imaging methods, including their benefits and limitations. Experts in the field guide the reader through both the physical principles and biomedical applications of each imaging modality, including description of typical setups and sample preparation. Volume 2 focuses on in vivo imaging methods, including intravital microscopy, ultrasound, MRI, CT and PET. Correlative multimodal imaging, (pre)clinical hybrid imaging techniques and multimodal image processing methods are also discussed. The volume concludes with a look ahead to emerging technologies and the future of imaging in biological and preclinical research. Key Features Provides an overview of fast-evolving in-vivo imaging technologies. Bridges biological and preclinical imaging. Written by imaging specialists with extensive expertise in their respective fields.
Author : Alexei Bogdanov,Kai Licha
Publisher : Springer Science & Business Media
Page : 269 pages
File Size : 51,6 Mb
Release : 2007-01-19
Category : Medical
ISBN : 9783540268093
The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.
Author : George C. Kagadis,Nancy L. Ford,Dimitrios N. Karnabatidis,George K. Loudos
Publisher : CRC Press
Page : 1080 pages
File Size : 43,7 Mb
Release : 2018-09-03
Category : Medical
ISBN : 9781315360423
The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Author : Alexei Bogdanov,Kai Licha
Publisher : Springer
Page : 258 pages
File Size : 52,5 Mb
Release : 2009-09-02
Category : Medical
ISBN : 3540800905
The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.
Author : Claudia Kuntner-Hannes,York Haemisch
Publisher : Springer
Page : 209 pages
File Size : 40,9 Mb
Release : 2018-12-22
Category : Medical
ISBN : 9783030029739
This book provides an accessible and comprehensive overview of the state of the art in multimodal, multiparametric preclinical imaging, covering all the modalities used in preclinical research. The role of different combinations of PET, CT, MR, optical, and optoacoustic imaging methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and software image registration methods and animal-specific factors are also discussed. The readily understandable text is enhanced by numerous informative illustrations that help the reader to appreciate the similarities to, but also the differences from, clinical applications. Image Fusion in Preclinical Applications will be of interest to all who wish to learn more about the use of multimodal/multiparametric imaging as a tool for in vivo investigations in preclinical medical and pharmaceutical research.
Author : Markus Rudin
Publisher : Springer Science & Business Media
Page : 412 pages
File Size : 46,5 Mb
Release : 2005-10-25
Category : Medical
ISBN : 3764371579
This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target validation to their use in clinical development programs. Chapters are devoted to the description of the drug discovery process, to the various imaging modalities preclinically and clinically, to applications of imaging during the optimization of a lead compound, addressing issues such as bioavailability and efficacy, and during drug safety evaluation.
Author : Claudia Kuntner,Bernhard Baumann,Adriana Tavares,Andreas Hess
Publisher : Frontiers Media SA
Page : 198 pages
File Size : 46,9 Mb
Release : 2020-12-16
Category : Science
ISBN : 9782889661725
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : María Luisa García Martín,Pilar López Larrubia
Publisher : Humana Press
Page : 464 pages
File Size : 44,8 Mb
Release : 2018-01-16
Category : Medical
ISBN : 1493975307
This volume discusses a variety of preclinical MRI methods and protocols to help technicians and researchers conduct studies in their respective fields. This book is organized into 7 parts: Part 1 covers the basics of MRI physics, relaxation, image contrast, and main acquisition sequences; Part 2 describes methodologies for diffusion, perfusion, and functional imaging; Part 3 looks at in vivo spectroscopy; Part 4 explores special MRI techniques that are less known in the field; Parts 5 and 6 discuss MRIs and MRSs in animal models of disease and the applications used to study them, and Part 7 looks at anesthesia and advanced contrast agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and thorough, Preclinical MRI: Methods and Protocols is a valuable resource for researchers interested in expanding their knowledge in this developing field.
Author : Brian R. Moyer,Narayan P.S. Cheruvu,Tom C.-C. Hu
Publisher : Springer Science & Business Media
Page : 401 pages
File Size : 45,8 Mb
Release : 2013-11-08
Category : Medical
ISBN : 9781461482475
The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this period by adding high value data, the images and the kinetic information they can provide, and cost-effective development alternative tools which potentially improve pivotal study designs. Imaging may identify safety issues early such as unwanted organ or tissue distributions, and then can serve advanced development with added certainty of a drug or biologic’s success to senior corporate management and investors. There are numerous textbooks, reference texts and treatises on medical imaging technologies, teaching tools on medical cases and physics books on the science of detector and computer interface systems. Rarely, in each of these are examples of medical imaging protocols and animal models of disease i.e. a text on methodology in drug development is currently unavailable.
Author : Anonim
Publisher : Elsevier
Page : 440 pages
File Size : 52,7 Mb
Release : 2004-07-10
Category : Science
ISBN : 9780080497235
This volume addresses current methods in biological imaging, including extensive sections on MRI, CAT, NMR, PET and other imaging techniques.
Author : Xunbin Wei,Bobo Gu
Publisher : Springer Nature
Page : 309 pages
File Size : 53,8 Mb
Release : 2021-05-29
Category : Medical
ISBN : 9789811576270
The book introduces readers to the basic principle of optical imaging technologies. Focusing on human disease diagnostics using optical imaging methods, it provides essential information for researchers in various fields and discusses the latest trends in optical imaging. In recent decades, there has been a huge increase in imaging technologies and their applications in human diseases diagnostics, including magnetic resonance imaging, x-ray computed tomography, and nuclear tomographic imaging. This book promotes further developments to extend optical imaging to a wider range of disease diagnostics. It is a valuable resource for researchers and students in the field of biomedical optics, as well as for clinicians.
Author : Anonim
Publisher : Elsevier
Page : 500 pages
File Size : 44,9 Mb
Release : 2004-07-10
Category : Science
ISBN : 9780080497242
This volume addresses current methods in biological imaging, including extensive sections on MRI, CAT, NMR, PET and other imaging techniques.
