Immune Infertility

Immune Infertility Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Immune Infertility book. This book definitely worth reading, it is an incredibly well-written.

Immune Infertility

Walter K.H. Krause,Rajesh K. Naz
Immune Infertility Book PDF

Author : Walter K.H. Krause,Rajesh K. Naz
Publisher : Springer
Page : 302 pages
File Size : 47,7 Mb
Release : 2016-11-02
Category : Health & Fitness
ISBN : 9783319407883

Get Book

Immune Infertility by Walter K.H. Krause,Rajesh K. Naz Pdf

This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

Immune Infertility

Walter K.H. Krause,Rajesh K. Naz
Immune Infertility Book PDF

Author : Walter K.H. Krause,Rajesh K. Naz
Publisher : Springer Science & Business Media
Page : 233 pages
File Size : 43,5 Mb
Release : 2009-08-17
Category : Health & Fitness
ISBN : 9783642013799

Get Book

Immune Infertility by Walter K.H. Krause,Rajesh K. Naz Pdf

Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2–30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.

Immune Infertility

Walter K.H. Krause,Rajesh K. Naz
Immune Infertility Book PDF

Author : Walter K.H. Krause,Rajesh K. Naz
Publisher : Springer
Page : 236 pages
File Size : 52,5 Mb
Release : 2011-04-20
Category : Health & Fitness
ISBN : 3642013805

Get Book

Immune Infertility by Walter K.H. Krause,Rajesh K. Naz Pdf

Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2–30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.

Oxford Textbook of Endocrinology and Diabetes

John A.H. Wass,Paul M. Stewart
Oxford Textbook of Endocrinology and Diabetes Book PDF

Author : John A.H. Wass,Paul M. Stewart
Publisher : Oxford University Press, USA
Page : 2158 pages
File Size : 43,8 Mb
Release : 2011-07-28
Category : Medical
ISBN : 9780199235292

Get Book

Oxford Textbook of Endocrinology and Diabetes by John A.H. Wass,Paul M. Stewart Pdf

Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Treatment of Infertility with Chinese Medicine E-Book

Jane Lyttleton
Treatment of Infertility with Chinese Medicine E Book Book PDF

Author : Jane Lyttleton
Publisher : Elsevier Health Sciences
Page : 517 pages
File Size : 46,5 Mb
Release : 2013-04-15
Category : Medical
ISBN : 9780702054327

Get Book

Treatment of Infertility with Chinese Medicine E-Book by Jane Lyttleton Pdf

The second edition of this popular text systematically addresses all aspects of treatment of infertility using Chinese medicine. Clinically focused and with a new easy-to-navigate design, the book begins by covering all the essential fundamentals you will need to understand and treat infertility, before going on to look at what Chinese medicine offers in the way of treatment for functional infertility in men and women, gynecological disorders which contribute to infertility and relevant lifestyle factors. Jane Lyttleton importantly devotes a large part of the book to discussing ways in which Chinese medicine and Western medicine might work together to overcome infertility, and details the increased experience over the past decade in working with IVF patients and their specialists. Leaps forward have also been made in the understanding of conditions such as Polycystic ovarian syndrome and immune infertility. New Features · Greatly expanded section on the place of Chinese medicine and IVF in treatment of infertility · New information on Polycystic ovarian disease and immune infertility and how Chinese medicine approaches their treatment · Updated and balanced advice on pre-conception care · Clinically focused, with easy-to-navigate design

Diagnosis and Management of Tubo-Uterine Factors in Infertility

R.F. Harrison,J. Bonnar,W. Thompson
Diagnosis and Management of Tubo Uterine Factors in Infertility Book PDF

Author : R.F. Harrison,J. Bonnar,W. Thompson
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 51,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401176217

Get Book

Diagnosis and Management of Tubo-Uterine Factors in Infertility by R.F. Harrison,J. Bonnar,W. Thompson Pdf

This is the second compilation of papers given during the Related Communica tions Sessions of the XIth International Federation of Fertility Societies World Congress held on June 26th-July 1st 1983 at the Royal Dublin Society, Dublin, Ireland. Except for Part I, where results of animal experimentations are gathered together, the volume is concerned solely with studies in the human. The role of infection and endometriosis in the aetiology and treatment of the tubo uteroperitoneal factor in infertility are the concern of Parts II and III. Diagnostic and therapeutic aspects of tubal disease are covered in Parts IV and V and the book ends with Part VI, chapters on the uterus and vagina. Laparoscopy and microsurgical techniques have undoubtedly transformed the diagnostic and therapeutic outlook in this area of infertility. This book shows you how far such techniques have progressed and how much there is yet to do. Dublin, 1983 Robert F. Harrison lohnBonnar William Thompson xi List of Contributors 5. A.Z. BADAWY J. ABE Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology Kyoto Prefectural University of Medicine Upstate Medical Center Kawarmachi-Hirokogi, Kamikyoku, Kyoto 750 E. Adams Street JAPAN 602 Syracuse, NY 13210 USA M. ALACHMAR "Marika Eliadi" Maternity Hospital 2 Helena Venizelos Square M. BERG Athens 115 21 Department of Clinical Sciences GREECE University of Tampere Teiskontie 35 W. ALBRICH SF-33520 Tampere Department of Obstetrics and Gynecology FINLAND University of Munich Marchioninistrasse D-8000 Munich 70 G.

Immunological Approaches to Contraception and Promotion of Fertility

Gursaran Talwar
Immunological Approaches to Contraception and Promotion of Fertility Book PDF

Author : Gursaran Talwar
Publisher : Springer Science & Business Media
Page : 442 pages
File Size : 54,7 Mb
Release : 2013-03-09
Category : Nature
ISBN : 9781468451405

Get Book

Immunological Approaches to Contraception and Promotion of Fertility by Gursaran Talwar Pdf

Contraceptive research has entered the new age of vaccines. Realistic prospects exist for the development of an entirely new battery of vaccines for use in human and veterinary medicine. Among them may be anti-fertility vaccines, based on physiological mechanisms applicable to either the female or male. This volume is a comprehensive review - a status report - of the subjects including fundamental work on the search for useful epitopes and ranging to applied vaccinology. One vaccine to prevent pregnancy, for use by women, has already been studied extensively. G.P. Talwar, the volume's editor and his colleagues in New Oelhi, India, published in 1976 a landmark series of papers describing the immunological properties of a preparation consisting of the alum-precipitated beta-subunit of human chorionic gonadotropin (hCG) chemically linked to tetanus toxoid. The principle of enhancing antigenicity of a self-protein by linkage of the epitope to a carrier protein was employed and tested clinically. These trials, carried out under the auspices of the Indian Council for Medical Research, were the first application of the carrier protein concept for a vaccine for human use. The encouraging results stimulated a wave of research not only on the use of hCG-based vaccines, but on other antigens as well.

Is Your Body Baby Friendly?

Alan E. Beer
Is Your Body Baby Friendly Book PDF

Author : Alan E. Beer
Publisher : Unknown
Page : 0 pages
File Size : 52,7 Mb
Release : 2019-03-04
Category : Health & Fitness
ISBN : 0978507851

Get Book

Is Your Body Baby Friendly? by Alan E. Beer Pdf

This revised edition of the landmark text includes the latest tests and treatments for those who are experiencing unexplained IVF failure, recurrent miscarriage, or long term infertility. An over activated immune response to pregnancy and blood clotting problems are now being identified in women with these previously "unexplained" conditions. Over half of fertility centers now recommend immune evaluation for women with a history of loss or two or more IVF failures. Centers that specialize in reproductive immunology are seeing success rates of over 85% within three cycles and even saving some couples from expensive and often futile IVF treatment. A fully updated list of all these centers, in the US and abroad, is provided in this book, making this a vital resource for all couples considering fertility treatment and looking for the best options in their area.

Immunology of Recurrent Pregnancy Loss and Implantation Failure

Joanna Kwak-Kim
Immunology of Recurrent Pregnancy Loss and Implantation Failure Book PDF

Author : Joanna Kwak-Kim
Publisher : Academic Press
Page : 457 pages
File Size : 46,6 Mb
Release : 2022-07-03
Category : Medical
ISBN : 9780323908061

Get Book

Immunology of Recurrent Pregnancy Loss and Implantation Failure by Joanna Kwak-Kim Pdf

Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches. Provides detailed immunological background for understanding the etiology and management of reproduction failure Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure Gives insights into various immunological and therapeutic approaches for reproduction failure

Reproductive Immunology

Satish Kumar Gupta
Reproductive Immunology Book PDF

Author : Satish Kumar Gupta
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 54,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401141970

Get Book

Reproductive Immunology by Satish Kumar Gupta Pdf

Reproductive Immunology is a compilation of research articles presented during the VII International Congress of Reproductive Immunology which was held in New Delhi, India on 27-30 October 1998. The articles pertain to the following six major themes: Molecular and Immunological Aspects of Sperm-Egg Interaction Embryonic-Endometrial Cross-Talk Immunobiology of Pregnancy Autoantibodies and Infertility Immunocontraception Mucosal Immunology and Reproductive Tract Infections . The first section deals with our current understanding of various steps involved in fertilization. The functional significance of sperm surface mannosidase and glutathione S-transferases to bind zona pellucida is described. The role of zona pellucida glycoproteins in the binding of sperm, induction of acrosome reactions and avoidance of polyspermy is discussed. In the second section, the role of various cytokines, growth factors and immunomodulatory agents in implantation of embryos is described. In the field of reproductive immunology, one of the major issues is to explore the successful gestation of the histoincompatible fetus in the uterus of an immunologically competent mother. The Proceedings presents the issues of paternal antigens at the feto-maternal interface and shows that Th2-type of immunity is involved in normal successful conception. The role of membrane-bound and soluble HLA-G in protecting the fetus from the lytic activities of maternal uterine and peripheral blood natural killer (NK) cells is also presented. Nature's experiments suggest that antibodies against sperm-specific antigens are responsible for infertility in some women. The possibility that an immunogenetic background contributes to production of sperm-immobilizing antibodies in infertile women is discussed in the section on autoantibodies and infertility. The Proceedings presents the issue of Th1-type cytokines in inducing recurrent spontaneous abortions of unexplained etiology. The roles of β2-glycoprotein 1 (β2-GP1)-dependent anticardiolipin antibody, lupus anticoagulant, antiphospholipids, anti-thyroid antibody and anti-nuclear antibody in miscarriages are also described. The rising global human population, particularly in the developing countries, has driven the need for new and safer methods of contraception. Fertility regulation by vaccines is thus an interesting proposition. The section on contraceptive vaccines discusses the latest advances in this area and describes the current status of vaccines based on βhCG, sperm antigens, zona pellucida glycoproteins, and riboflavin carrier proteins. The issues of mucosal immunity and strategies for enhancing local genital immune responses to combat HIV infection is discussed. The role of inflammatory and related cytokines in chorioamnionitis is described. The contents of this Proceedings describes various facets of reproductive immunology which will help us to design strategies to combat genital infections and miscarriages caused by immunological etiology. Descriptions of the molecular basis of gamete recognition, implantation and survival of the allogenic fetus will help in designing strategies for overcoming infertility and also new contraceptive approaches. The Proceedings will be useful to researchers and clinicians involved in basic or applied research in the disciplines of reproductive biology, reproductive immunology, and obstetrics and gynecology.

The Immunology of Human Reproduction

Isaac T. Manyonda
The Immunology of Human Reproduction Book PDF

Author : Isaac T. Manyonda
Publisher : CRC Press
Page : 156 pages
File Size : 46,8 Mb
Release : 2006-01-13
Category : Medical
ISBN : 9780203488607

Get Book

The Immunology of Human Reproduction by Isaac T. Manyonda Pdf

Understanding immunology is increasingly important in obstetrics and gynecology. Written primarily to meet the needs of practicing obstetricians and gynecologists, this book explores the role of immunological processes in reproduction. It presents immunologic concepts and illustrates important points with examples familiar to the clinician. The boo

Reproductive Immunology

Gil Mor
Reproductive Immunology Book PDF

Author : Gil Mor
Publisher : Academic Press
Page : 462 pages
File Size : 51,5 Mb
Release : 2021-02-12
Category : Medical
ISBN : 9780128189306

Get Book

Reproductive Immunology by Gil Mor Pdf

Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs. Shows the detailed evaluation of the knowledge related to each immune cell type in the pregnant and not pregnant uterus Evaluates each immune cell type and its function during specific reproductive events Provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series

Immunological Influence on Human Fertility

Barry Boettcher
Immunological Influence on Human Fertility Book PDF

Author : Barry Boettcher
Publisher : Academic Press
Page : 384 pages
File Size : 42,6 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9781483268958

Get Book

Immunological Influence on Human Fertility by Barry Boettcher Pdf

Immunological Influence on Human Fertility covers the proceedings of the Workshop on Fertility in Human Reproduction, held at the Department of Biological Science, University of Newcastle, Australia on July 11 -13, 1977. The book focuses on topics on the immunological control of human and animal fertility. The selection first discusses the zona pellucida as a possible target in immunocontraception, immunological aspects of vasectomy, and the clinical significance of antibodies to spermatozoa. Topics include performance and significance of the SCMC-test, antibodies and fertility after vasovasostomy, vasectomy and the blood-testis barrier, cellular immune response, active and passive immunization, and tissue and species specificity. The book then tackles the nature of the barrier to autoimmunity in the excurrent ducts of the mammalian testis, immune activities of the male and female reproductive tracts, and isolation of spermatozoal antigens. The manuscript examines the immunological capacity of the male genital tract, clinical significance of antibodies to antigens of the reproductive tract, immunological aspects of vasectomy, and antigens of human trophoblasts. The text also takes a look at the immunological and anti-tumor effects of orchidectomy, immune infertility and approaches to treatment, natural insemination as an immune phenomenon, and modified seminal plasma antigens and subfertility. The selection is a valuable source of information for researchers wanting to study the immunological control of human and animal fertility.

Mechanisms of Life History Evolution

Thomas Flatt,Andreas Heyland
Mechanisms of Life History Evolution Book PDF

Author : Thomas Flatt,Andreas Heyland
Publisher : OUP Oxford
Page : 506 pages
File Size : 55,8 Mb
Release : 2011-05-12
Category : Science
ISBN : 9780191621024

Get Book

Mechanisms of Life History Evolution by Thomas Flatt,Andreas Heyland Pdf

Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction, and survival and by investigating the trade-offs that constrain the evolution of these traits. Although life history theory has made enormous progress in explaining the diversity of life history strategies among species, it traditionally ignores the underlying proximate mechanisms. This novel book argues that many fundamental problems in life history evolution, including the nature of trade-offs, can only be fully resolved if we begin to integrate information on developmental, physiological, and genetic mechanisms into the classical life history framework. Each chapter is written by an established or up-and-coming leader in their respective field; they not only represent the state of the art but also offer fresh perspectives for future research. The text is divided into 7 sections that cover basic concepts (Part 1), the mechanisms that affect different parts of the life cycle (growth, development, and maturation; reproduction; and aging and somatic maintenance) (Parts 2-4), life history plasticity (Part 5), life history integration and trade-offs (Part 6), and concludes with a synthesis chapter written by a prominent leader in the field and an editorial postscript (Part 7).

Immunological Aspects of Reproduction and Fertility Control

J.P. Hearn
Immunological Aspects of Reproduction and Fertility Control Book PDF

Author : J.P. Hearn
Publisher : Springer
Page : 272 pages
File Size : 50,6 Mb
Release : 1980-07-31
Category : Medical
ISBN : UCAL:B4513348

Get Book

Immunological Aspects of Reproduction and Fertility Control by J.P. Hearn Pdf

The no-man's-land between reproductive physiology and immunology is becoming crowded. The last 10 years have seen a revolution in our under standing of many reproductive processes, brought about by the application of ever more sophisticated immunological methods. The increasing precision of these techniques has given us specific ways of assaying, enhancing or blocking hormonal mechanisms to yield more critical and interpretable information. In this volume eleven authors have presented the current status and future prospects of some immunological aspects of reproduction and fertility con trol. These include the relationships between mother and fetus, the diagnosis of pregnancy, the immunological complications seen in clinical management of human reproduction and some novel approaches for immunological control of fertility. We hope that in these chapters we have achieved an up-to-date account of a fast-moving field that calls on several disciplines. We intend the book to provide an adequate background and a current review for research workers and clinicians who wish both to understand the complex mechanisms involved and to develop improved scientific and clinical methods. We hope too that the student and newcomer will find this a useful reference book.