Immunodeficiency Disorders

Author : Nima Rezaei,Asghar Aghamohammadi,Luigi D. Notarangelo
Publisher : Springer
Page : 582 pages
File Size : 48,9 Mb
Release : 2016-11-30
Category : Medical
ISBN : 9783662529096

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Primary Immunodeficiency Diseases by Nima Rezaei,Asghar Aghamohammadi,Luigi D. Notarangelo Pdf

The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Author : Amos Etzioni,Hans D. Ochs
Publisher : Academic Press
Page : 377 pages
File Size : 45,8 Mb
Release : 2014-09-13
Category : Medical
ISBN : 9780124115545

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Primary Immunodeficiency Disorders by Amos Etzioni,Hans D. Ochs Pdf

Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established Provides stimulating discussions on developing new medical therapiesHighlights the importance of studying humans to understand mechanisms of disease that affect humans

Author : Jonathan A. Bernstein
Publisher : Springer Nature
Page : 409 pages
File Size : 53,7 Mb
Release : 2021-01-28
Category : Medical
ISBN : 9783030571573

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Primary and Secondary Immunodeficiency by Jonathan A. Bernstein Pdf

This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.

Author : Hans D. Ochs,C. I. Edvard Smith,Jennifer Puck
Publisher : Oxford University Press, USA
Page : 745 pages
File Size : 40,5 Mb
Release : 2007
Category : Medical
ISBN : 9780195147742

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Primary Immunodeficiency Diseases by Hans D. Ochs,C. I. Edvard Smith,Jennifer Puck Pdf

This book will present the principles of immunology, genetics, and molecular biology as they pertain to the primary immunodeficiency diseases; the hallmark of these diseases is an increased susceptbility to infections. The major authorities in the field address both the scientific aspects and the practical, clinical aspects of these disorders, including therapeutic strategies. The second edition features 11 new chapters as well as a significant updating of all the first edition material in this fast-developing field. The book should appeal to geneticists, pediatricians, immunologists, infectio.

Author : Jordan S. Orange
Publisher : Unknown
Page : 0 pages
File Size : 42,8 Mb
Release : 2008
Category : Immunological deficiency syndromes
ISBN : 1416058567

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Immunodeficiency Disorders by Jordan S. Orange Pdf

Topics include: "Genetic Diagnosis ofPrimary Immunodeficiencies","IPEX syndrome and Treg deficiency in primaryimmunodeficiency","DiGeorge syndrome and other thymic hypoplasias","Common VariableImmunodeficiency", "Hyper IgE syndromes","Hyper IgM syndromes","Hematophagocyticlymphohistiocytoses", "Defects of the Toll LikeReceptor System", "Congenital Neutropenias", "Advances in Severe Combined Immunodeficiency", "Genetic Defects of Apoptosis and PrimaryImmunodeficiency", "Principles of and Advances inimmunoglobuin replacement therapy for primary immunodeficiency", "Gene therapy for primary immunodeficiency"

Author : Kathleen E. Sullivan,E. Richard Stiehm
Publisher : Academic Press
Page : 1334 pages
File Size : 45,8 Mb
Release : 2020-05-23
Category : Medical
ISBN : 9780128172957

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Stiehm's Immune Deficiencies by Kathleen E. Sullivan,E. Richard Stiehm Pdf

Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians Fills an increasingly deep gap in the information available to clinicians Presents both clinical management and scientific advances for immune deficiencies Provides a primary resource for physicians in the field of immunodeficiencies Includes website access to a range of videos relevant to the topics discussed

Author : Pedro A. de Alarcón,Eric J. Werner,Robert D. Christensen,Martha C. Sola-Visner
Publisher : Cambridge University Press
Page : 501 pages
File Size : 47,6 Mb
Release : 2021-02-18
Category : Medical
ISBN : 9781108488983

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Neonatal Hematology by Pedro A. de Alarcón,Eric J. Werner,Robert D. Christensen,Martha C. Sola-Visner Pdf

An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.

Author : Hans D. Ochs,,C. I. Edvard Smith,,Jennifer M. Puck,
Publisher : Oxford University Press
Page : 930 pages
File Size : 45,5 Mb
Release : 2013-09
Category : Health & Fitness
ISBN : 9780195389838

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Primary Immunodeficiency Diseases by Hans D. Ochs,,C. I. Edvard Smith,,Jennifer M. Puck, Pdf

This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases.

Author : Lisa Kobrynski
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 48,9 Mb
Release : 2018-11-22
Category : Medical
ISBN : 9780323654425

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Primary Immunodeficiency Disorders by Lisa Kobrynski Pdf

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.

Author : Raif Geha,FRED Rosen
Publisher : Garland Science
Page : 353 pages
File Size : 50,9 Mb
Release : 2010-07-29
Category : Medical
ISBN : 9781135153069

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Case Studies in Immunology by Raif Geha,FRED Rosen Pdf

This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.

Author : Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Publisher : Unknown
Page : 392 pages
File Size : 41,5 Mb
Release : 2006
Category : Immunization
ISBN : 0660193922

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Canadian Immunization Guide by Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization Pdf

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Author : A.D.B Webster
Publisher : Springer Science & Business Media
Page : 192 pages
File Size : 46,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400912755

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Immunodeficiency and Disease by A.D.B Webster Pdf

The AIDS epidemic has popularized immune deficiency and has led to a rapid increase in the funding for research into the effect of viruses on immunity. There is now a real possibility of finding out whether some of the rare, so-called 'primary' immunodeficiency syndromes of children and adults, first described in the 1950s, may have a viral aetiology. Most of these syndromes have already been extensively reviewed more than once over the past 10 years, and their diagnosis and management is now included in most standard medical textbooks. In this volume, I have chosen to highlight what I consider to be the potentially exciting aspects of immunodeficiency in humans, hopefully providing clinicians and medical academics with some insight into the recent breakthroughs and disappointments. There are three chapters discussing viral interactions with the immune system. Although much has been written about AIDS already, I make no apology for including an extensive review of both the clinical and laboratory aspects of this disease. AIDS is an important precedent, and it is likely that other less pathogenic retroviruses will eventually turn dut to cause some of the rarer immunodeficiency disorders in children and adults. For instance, it has long been suspected that viruses may cause some of the non-familial types of severe combined immunodeficiency in infants; in fact HIV-I infection now has to be considered in the differential diagnosis.

Author : Ranjit Kumar Chandra
Publisher : Unknown
Page : 324 pages
File Size : 46,8 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015008069844

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Primary and Secondary Immunodeficiency Disorders by Ranjit Kumar Chandra Pdf

Author : Anthony Montanaro
Publisher : Elsevier Health Sciences
Page : 778 pages
File Size : 51,6 Mb
Release : 2016-01-07
Category : Medical
ISBN : 9780323413350

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Primary Immunodeficiency Disorders, An Issue of Immunology and Allergy Clinics of North America 35-4, by Anthony Montanaro Pdf

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Anthony Montanaro, MD, is devoted to Primary Immunodeficiency Disorders. Dr. Montanaro has assembled a group of expert authors to review the following topics: Overview of Immunodeficiency Disorder; Severe Combined Immunodeficiency Disorder; Specific Antibody Deficiencies; Common Variable Immunodeficiency; Pulmonary Manifestations of Primary Immunodeficiency Disorders; Approach to the Child with Recurrent Infections; Immunoglobulin Treatment for Primary Immunodeficiency; Bone Marrow Transplantation for Primary Immunodeficiency; and Autoimmune Manifestations of Primary Immunodeficiency.

Author : Antonio L. Teixeira,Moises E. Bauer
Publisher : Oxford University Press, USA
Page : 323 pages
File Size : 54,9 Mb
Release : 2019-01-18
Category : Science
ISBN : 9780190884468

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Immunopsychiatry by Antonio L. Teixeira,Moises E. Bauer Pdf

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.