Immunological Aspects Of The Liver And Gastrointestinal Tract

Author : A. Ferguson,R.N.M. MacSween
Publisher : Springer Science & Business Media
Page : 413 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401161503

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Immunological Aspects of the Liver and Gastrointestinal Tract by A. Ferguson,R.N.M. MacSween Pdf

We have been privileged to start our academic careers at the begin ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined. In the early 1960s IgA was reported to be the main secretory immunoglobulin, immunoblasts were shown to home to the intestinal mucosa and certain serum autoantibodies were described in patients with chronic liver disease. Shortly thereafter IgE and Australia antigen were discovered. Parallel advances in clinical investigation, in particular closed biopsy techniques, facilitated correlation of morphological changes with im munological mechanisms in disease of the gastrointestinal tract and liver. Only 10 years later, the concepts of immunity and hypersensitivity are regularly applied to the pathogenesis, diagnosis, treatment and prog nosis of many chronic diseases in these organs. In designing this book we have attempted to integrate theorectical and clinical immunology as they pertain in 1975; our ultimate aim is aptly described by Brachet as quoted by Professor Paronetto (page 319). We would like to think that this review provides a basis for the next major advances in the fields of gastrointestinal and hepatic immunology. As we see it, the outstanding problem in both sites is how to produce protective immunity without hypersensitivity.

Author : H.C. Thomas,P.A. Miescher,H.J. Mueller-Eberhard
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642684463

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Immunological Aspects of Liver Disease by H.C. Thomas,P.A. Miescher,H.J. Mueller-Eberhard Pdf

Howard C. Thomas In normal subjects the regulatory apparatus of the immune system permits responses to foreign antigens but suppresses those directed to "self' components. Autoimmune disease occurs as a failure ofthis system either as a result of a primary defect in the regulatory apparatus (primary autoimmunization) or because of a change in the antigenicity of the tissues (secondary autoimmunization). Autoaggressive reactions are characterised by the presence of autoantibodies. When these are directed to membrane displayed antigens (Fig. 1) they are probably of importance in the lysis of hepatocytes. Those directed to cytoplasmic antigens may be useful diagnostically but are of unknown pathogenic significance. When no extrinsic aetiological factor can be identified, the process is assumed to be the result of a failure ofthe regulatory system, allowing the spontaneous expansion of a clone of autoreactive lymphocytes. The defect may be generalised or specific to certain groups of self-antigens and thus the autoimmune disease may be either multi- or unisystemic. The recent development of techniques to enumerate and measure the functional activity of the suppressor lymphocytes which control the effector limbs of the immune system has enabled investigators to test whether the various purported autoimmune diseases do have as their basis a generalised defect in immunoregu lation. Assessment of antigen-specific immunoregulatory function is, however, not yet readily available. liver Membrane I Antigen (LIM) I Liver I HLA, A, B, C, Sensitisation to Specific -;::!IIIL. .

Author : Stephan R. Targan,Fergus Shanahan
Publisher : Igaku-Shoin Medical Publishers
Page : 680 pages
File Size : 54,9 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015015468815

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Immunology and Immunopathology of the Liver and Gastrointestinal Tract by Stephan R. Targan,Fergus Shanahan Pdf

Author : Martin F. Heyworth,Albert L. Jones
Publisher : Lippincott Williams & Wilkins
Page : 250 pages
File Size : 50,8 Mb
Release : 1988
Category : Cellular immunity
ISBN : UOM:39015012556182

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Immunology of the Gastrointestinal Tract and Liver by Martin F. Heyworth,Albert L. Jones Pdf

Author : David R. Triger
Publisher : Butterworth-Heinemann
Page : 260 pages
File Size : 55,9 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015011785980

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Clinical Immunology of the Liver and Gastrointestinal Tract by David R. Triger Pdf

Author : Y.R. Mahida
Publisher : Springer Science & Business Media
Page : 376 pages
File Size : 46,8 Mb
Release : 2001-05-31
Category : Medical
ISBN : 0792370716

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Immunological Aspects of Gastroenterology by Y.R. Mahida Pdf

Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

Author : M. Lukás,M.P. Manns,J. Spicak,E.-F. Stange
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 53,6 Mb
Release : 2004-06-30
Category : Medical
ISBN : 0792387929

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Immunological Diseases of Liver and Gut by M. Lukás,M.P. Manns,J. Spicak,E.-F. Stange Pdf

This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.

Author : Richard Heatley
Publisher : Cambridge University Press
Page : 412 pages
File Size : 54,6 Mb
Release : 1994-10-27
Category : Medical
ISBN : 9780521445092

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Gastrointestinal and Hepatic Immunology by Richard Heatley Pdf

This 1994 volume summarizes basic scientific advances in the area of the gut immune system and the immune abnormalities relevant to gastrointestinal and liver disease.

Author : Ralph Wright (M.D.)
Publisher : Hodder Education
Page : 148 pages
File Size : 44,8 Mb
Release : 1977
Category : Medical
ISBN : UOM:39015000894991

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Immunology of Gastrointestinal and Liver Disease by Ralph Wright (M.D.) Pdf

Author : Y.R. Mahida
Publisher : Springer Science & Business Media
Page : 359 pages
File Size : 40,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401007900

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Immunological Aspects of Gastroenterology by Y.R. Mahida Pdf

Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

Author : J. B. Solomon
Publisher : Elsevier
Page : 591 pages
File Size : 45,6 Mb
Release : 2014-05-09
Category : Medical
ISBN : 9781483189710

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Aspects of Developmental and Comparative Immunology by J. B. Solomon Pdf

Aspects of Developmental and Comparative Immunology contains the proceedings of the 1st Congress of Developmental and Comparative Immunology, held from July 27 to August 1, 1980 in Aberdeen, Scotland. The papers explore various aspects of developmental and comparative immunology and cover topics ranging from the major histocompatibility complex (MHC) and membrane immunoglobulins to idiotypes and diversity, comparative ontogeny, and evolution of lymphoid organ function. Comprised of 105 chapters, this volume begins with an overview of how the host immune system utilizes polymorphic MHC antigens as the principal tool for pseudo-self versus true self distinction. The reader is then introduced to the immunology of earthworms, membrane immunoglobulins, idiotypes, and diversity. Subsequent chapters focus on the evolution of lymphoid organs in vertebrates; differentiation clocks in comparative immunology of mammals and birds; immunorecognition in invertebrates such as insects and gastropods; and the phylogeny of leucocytes in vertebrates and invertebrates. The remaining sections deal with stem cells, immune responses of gut-associated lymphoepithelial tissue, and the ontogeny of resistance to infection as well as the ontogeny of killer cells. Finally, the immunology of fish, amphibians, reptiles, chickens, and mammals is examined. This monograph will be of interest to immunobiologists.

Author : Ruth Porter,Julie Knight
Publisher : John Wiley & Sons
Page : 192 pages
File Size : 52,7 Mb
Release : 2009-09-16
Category : Medical
ISBN : 9780470717967

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Immunology of the Gut by Ruth Porter,Julie Knight Pdf

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Author : Cris S. Constantinescu,Rāzvan I. Arsenescu,Violeta Arsenescu
Publisher : Springer
Page : 337 pages
File Size : 52,8 Mb
Release : 2016-05-24
Category : Medical
ISBN : 9783319286099

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Neuro-Immuno-Gastroenterology by Cris S. Constantinescu,Rāzvan I. Arsenescu,Violeta Arsenescu Pdf

This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver. After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases. Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.

Author : Martha M. Eibl,Christoph Huber,Hans H. Peter,Ulrich Wahn
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642784385

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Symposium in Immunology III by Martha M. Eibl,Christoph Huber,Hans H. Peter,Ulrich Wahn Pdf

The Symposia in Immunology were organized to bring important new information on the expanding field of immunology to practicing physicians interested in the field. Highly renowned basic scientists share their results with physicians conducting clinical research and those experienced in the treatment of the respective diseases. This series of symposia is planned to cover different areas of immunology and will help to close the gap between special achievements of scientists and practicing physicians.

Author : Pablo Muriel
Publisher : Academic Press
Page : 914 pages
File Size : 41,9 Mb
Release : 2017-03-02
Category : Medical
ISBN : 9780128043219

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Liver Pathophysiology by Pablo Muriel Pdf

Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.