Immunology Of The Skin

Author : Kenji Kabashima
Publisher : Springer
Page : 510 pages
File Size : 40,9 Mb
Release : 2016-03-10
Category : Medical
ISBN : 9784431558552

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Immunology of the Skin by Kenji Kabashima Pdf

This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the mechanisms of skin diseases. The skin is one of the immune organs and is continually exposed to foreign antigens and external stimuli that must be monitored and characterized for possible elimination. Upon exposure to foreign antigens, the skin can elicit a variety of immune responses in harmony with skin components that include keratinocytes, dendritic cell subsets, mast cells, basophils, fibroblasts, macrophages, gamma-delta T cells, neutrophils, myeloid-derived suppressor cells, vascular and lymphatic cells, hair follicles, platelets, and adipose tissues, among others. In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology.

Author : Jan D. Bos
Publisher : CRC Press
Page : 768 pages
File Size : 45,6 Mb
Release : 1997-04-10
Category : Medical
ISBN : 0849340160

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Skin Immune System (SIS) by Jan D. Bos Pdf

Immunodermatology is a field covering the majority of skin diseases, including the most prevalent onesin the general population. The Second Edition of Skin Immune System (SIS) discusses immune-mediated skin diseases and disease groups in which the SIS plays a role. It covers major findings in immunophysiology and immunopathology that have occurred since the introduction of the First Edition in 1990. As the subtitle indicates, the Second Edition adds a new emphasis on cutaneous immunology, and also includes new information on immune-based therapeutic interventions and methods, such as phototherapy and the immunological therapy of skin cancer. The book contains Part I, with introductory chapters; Part II, with descriptions of the cellular elements; and Part III, which describes the humoral and molecular components of SIS. Part IV follows to integrate the facts described in Parts II and III into concepts of pathophysiology. It contains a number of concepts entitled "response patterns" that describe how the constitutional elements of SIS work together. New in this edition are the descriptions of immunodermatological diseases individually described in Part V. Part VI is also all new and summarizes principles of immunotherapy.

Author : Jan D. Bos
Publisher : Informa Healthcare
Page : 824 pages
File Size : 49,9 Mb
Release : 2005
Category : Medical
ISBN : 0849319595

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Skin Immune System by Jan D. Bos Pdf

Top scientific authors contribute their expertise and put a wealth of complex information into perspective in Skin Immune System: Cutaneous Immunology & Clinical Immunodermatology, Third Edition. This edition provides an overview of the skin immune system (SIS), a totally updated section on immunodermatological diseases, and six new chapters. Part I presents historical and comparative information on immunodermatology and includes a new chapter on the immunogenetics of inflammatory skin disease, while Part II covers the cellular elements of SIS and highlights newly defined functional subclasses of cells. Part III describes the humoral elements of SIS and provides two new chapters which focus on defensins and cathelicidins, and on the chemokines of human skin. Part IV discusses how the cellular and humoral elements of SIS interact under different circumstances and includes a new chapter on signal transduction pathways in cutaneous immunology. Part V focuses on dermatological diseases with a significant immunological background with a new chapter on the immunology of cutaneous drug eruptions, followed by Part VI on immunotherapy in dermatology, which features a new chapter reflecting the recent wave of products from biotechnology. Since the publication of the previous editions, a great deal of significant information has become available in almost all areas of cutaneous immunology and clinical immunodermatology. This progress has now been reflected in a completely updated and expanded resource.

Author : Fatima Conceição-Silva,Fernanda Nazaré Morgado,Fabienne Tacchini-Cottier,Roberta Olmo Pinheiro
Publisher : Frontiers Media SA
Page : 223 pages
File Size : 45,7 Mb
Release : 2021-10-14
Category : Science
ISBN : 9782889714926

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The Skin Immune Response to Infectious Agents by Fatima Conceição-Silva,Fernanda Nazaré Morgado,Fabienne Tacchini-Cottier,Roberta Olmo Pinheiro Pdf

Author : Richard D. Granstein,Thomas A. Luger
Publisher : Springer Science & Business Media
Page : 248 pages
File Size : 55,6 Mb
Release : 2009-02-08
Category : Medical
ISBN : 9783540359890

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Neuroimmunology of the Skin by Richard D. Granstein,Thomas A. Luger Pdf

Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 42,8 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Yoshiaki Toyama,Atsushi Miyawaki,Masaya Nakamura,Masahiro Jinzaki
Publisher : Springer Nature
Page : 292 pages
File Size : 45,7 Mb
Release : 2019-10-02
Category : Medical
ISBN : 9789811379086

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Make Life Visible by Yoshiaki Toyama,Atsushi Miyawaki,Masaya Nakamura,Masahiro Jinzaki Pdf

This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 53,5 Mb
Release : 2005
Category : MEDICAL
ISBN : 0367801787

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Skin Immune System (SIS) by Anonim Pdf

Top scientific authors contribute their expertise and put a wealth of complex information into perspective in Skin Immune System: Cutaneous Immunology & Clinical Immunodermatology, Third Edition. This edition provides an overview of the skin immune system (SIS), a totally updated section on immunodermatological diseases, and six new chapters. Part I presents historical and comparative information on immunodermatology and includes a new chapter on the immunogenetics of inflammatory skin disease, while Part II covers the cellular elements of SIS and highlights newly defined functional subclasse.

Author : Jan D. Bos
Publisher : CRC Press
Page : 520 pages
File Size : 40,6 Mb
Release : 1990-03-26
Category : Medical
ISBN : 0849349451

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Skin Immune System (SIS) by Jan D. Bos Pdf

The aim of this comprehensive volume is to provide detailed and well-referenced information pertaining to the immunology of skin, particularly that of man. It includes a short description of comparative immunology plus an introduction into the skin immune system and skin associated lymphoid tissues. This section also describes adhesion molecules and their role in cell migration pathways. This interesting text provides up-to-date knowledge of keratinocytes, lymphocytes, Langerhans cells, monocytes, endothelial cells and mast cells. It describes the humoral constituents of the human integument's defense system, as well as the major response patterns of the skin immune system. This easy-to-read reference outlines future developments which are to be expected in the field of immunodermatology and the immunobiology of the integument. Those involved with immunology, biology, and dermatology will find this book interesting, informative, and indispensable.

Author : Nathalie Boulanger
Publisher : Academic Press
Page : 516 pages
File Size : 52,5 Mb
Release : 2018-01-20
Category : Science
ISBN : 9780128114377

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Skin and Arthropod Vectors by Nathalie Boulanger Pdf

Recent research on skin immunity and the skin microbiome reveals the complexity of the skin and its importance in the development of immunity against arthropod-borne diseases. In diseases such as malaria, borreliosis, leishmaniasis, trypanosomiasis, etc., the skin interface has been shown as an essential site for pathogens to hide from the immune system, and as a potential site of persistence. Only very few vaccines have been successfully developed so far against these diseases, likely because of an insufficient understanding on the development of skin immunity against pathogens. Skin and Arthropod Vectors expands our knowledge on the role of the skin interface during the transmission of arthropod-borne diseases and particularly its immunity. This work may support researchers who strive for developing more efficient diagnostic tools and vaccines. It also gives scientists and advanced students working in related areas a better insight on how humans and animals are attractive to arthropods to develop better repellents, or to set up transgenic arthropods. Offers the only compilation of research focusing on both the skin interface and arthropod vectors, with contributions from international experts Advances research in the effort toward generating more effective diagnostic tools and vaccines focusing on the skin interface Can also serve as supplemental material for dermatology lectures or specialized lectures on medical entomology and skin immunity

Author : Xing-Hua Gao,Hong-Duo Chen
Publisher : Springer
Page : 385 pages
File Size : 44,7 Mb
Release : 2016-12-23
Category : Medical
ISBN : 9789402409024

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Practical Immunodermatology by Xing-Hua Gao,Hong-Duo Chen Pdf

This book discusses typical skin diseases from an immunological point of view, introducing the latest immunological techniques and practices. It begins with a brief overview of the human immune system, including the basic concepts and principles as well as the general symbols used in immunology. Part Two describes the human skin as an integral part of the immune system, explaining the immunological roles of major cellular and molecular composites in the skin. Part Three illustrates typical skin diseases that have immunological involvement (immunodermatological conditions). It describes 40 skin diseases, focusing on immunological causes, pathogenesis, pattern of reaction and treatment choices and responses. The final part discusses advanced immunodiagnostics and immunotherapy in dermatology, providing detailed descriptions of immune techniques for the diagnosis of skin diseases, their principles and background, indications, requirements for sampling, test protocols, interpretation of results and trouble shooting. This work offers insights into both the systemic immune system and the skin immune system, and integrates the information into discussions of clinical diseases, relevant immune techniques and immunological drugs. Presenting the latest advances in clinical immunology, it is an invaluable resource for dermatologists, residents and graduate students in dermatology.

Author : Karel A. Schat,Bernd Kaspers,Pete Kaiser
Publisher : Academic Press
Page : 456 pages
File Size : 52,8 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780123972729

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Avian Immunology by Karel A. Schat,Bernd Kaspers,Pete Kaiser Pdf

The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research

Author : Brian J. Nickoloff,Frank O. Nestle
Publisher : Karger Medical and Scientific Publishers
Page : 391 pages
File Size : 50,9 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9783805583916

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Dermatologic Immunity by Brian J. Nickoloff,Frank O. Nestle Pdf

Nickeloff (skin cancer research, Cardinal Bernardin Cancer Center, Chicago) and Nestle (cutaneous medicine and immunotherapy, King's College, London School of Medicine at Guy's, UK) assemble 19 review articles on autoimmune disease processes that affect the skin, covering both humoral and cellular immunity. The etiology, cellular and molecular mechanisms, therapeutic strategies, and pathophysiology of diseases such as psoriasis, dermatitis, cutaneous lupus erythematosus, vitiligo, and scleroderma are discussed by individuals in dermatology, genetics, immunology, and pathology who are based around the world. The book is aimed at clinical researchers, students, allergists, immunologists, dermatologists, and internists.

Author : Anthony A. Gaspari,Stephen K. Tyring,Daniel H. Kaplan
Publisher : Springer
Page : 895 pages
File Size : 41,5 Mb
Release : 2017-04-24
Category : Medical
ISBN : 9783319297859

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Clinical and Basic Immunodermatology by Anthony A. Gaspari,Stephen K. Tyring,Daniel H. Kaplan Pdf

This updated volume provides a “user-friendly” reference for dermatologists, dermatology residents and students, as well as for health care workers in related fields to better understand immune-mediated skin diseases and their therapies. The focus is on what is needed by the physician/resident or student for betting understanding the pathophysiology of the disease as well as the mechanisms of action of the therapies. The reader can easily read about groups of related diseases as well as groups of related therapies. The level of complexity of the book is such that it has practical applications on a daily basis but can also be used by the resident as a teaching tool and as a handy source of review for the boards. In addition, it can be used the practicing dermatologist to study for recertification. The scope of the book is immunology, immunogenetics, immunopathology and immunopharmacology as they relate to clinical dermatology.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf