Immunopharmacology In Autoimmune Diseases And Transplantation

Author : L. Endresen,Ø. Førre,H.E. Rugstad
Publisher : Springer Science & Business Media
Page : 424 pages
File Size : 41,5 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489911674

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Immunopharmacology in Autoimmune Diseases and Transplantation by L. Endresen,Ø. Førre,H.E. Rugstad Pdf

This book incorporates the latest advances in immunopharmacological treatment. One objective has been to provide appropriate bridges between the basic sciences of immunology and pharmacology on the one hand and clinical medicine on the other. A further intention has been to emphasize those advances in immunology and pharmacology that are of clinical importance while retaining those facts that, while not new, remain clinically useful. The immunology section provides the necessary background for immunopharmacologi cal treatment. The chapters on individual cell types include normal surface markers, mode of activation, and activation markers and functions in health and disease. The chapters on pharmacology give comprehensive information on immunosuppressive drugs in regular use today, their biochemical and cellular mechanisms of action, pharmaco kinetics, dosage regimens, therapeutic responses, adverse reactions, and drug interactions and tolerance. In addition, certain therapeutic principles that are still in an experimental phase are described, for example, immunotoxins, thymic hormones, and interleukins. The book presents comprehensive information on various autoimmune diseases, the etiopathogenetic immune mechanisms where these are known, and the current possibilities for immunopharmacological intervention. The specific disease section also covers rare situations, fluctuations in disease patterns, and subgroups of patients and immunophar macological treatment in these situations. Altogether, the book represents a practical textbook for clinicians and advanced students who want to be updated on therapeutic principles with regard to autoimmune diseases and transplantation.

Author : Clive P. Page,M. Elisabeth Davies,John T. Dingle
Publisher : Elsevier
Page : 296 pages
File Size : 41,7 Mb
Release : 1994-03-07
Category : Medical
ISBN : 0122063457

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Immunopharmacology of Joints and Connective Tissues by Clive P. Page,M. Elisabeth Davies,John T. Dingle Pdf

The consequences for diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial asthma, rheumatoid athritis, and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their preventions and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drug development. As a consequence, this area has not gained the prominence of other new fields such as molecular pharmacology or neuropharmacology, and a focal information source for many pharmacologists interested in diseases of the immune system remains unpublished. The Handbook of Immunopharmacology series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have distinctly pharmacological bias to their research. The series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory responses that can affect them ("Systems"). The third covers different classes of diseases as well as those under development ("Drugs").

Author : Duncan Dartrey Adams,Christopher Dartrey Adams
Publisher : Springer Science & Business Media
Page : 65 pages
File Size : 44,6 Mb
Release : 2013-08-13
Category : Medical
ISBN : 9789400769373

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Autoimmune Disease by Duncan Dartrey Adams,Christopher Dartrey Adams Pdf

This book describes how the Jerne-Burnet Forbidden Clone Theory and the Adams-Knight H Gene Theory, solved the pathogenesis and genetics of the autoimmune diseases showing how specific immunotherapy and prophylaxis can be developed. Furthermore, Ebringer's discovery of two microbial triggers of autoimmune diseases is described and the conclusion drawn that all autoimmune diseases have microbial triggers, so will be preventable by the finding of the triggers and vaccination against them.

Author : Manzoor M. Khan
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 51,5 Mb
Release : 2008-12-19
Category : Medical
ISBN : 9780387779768

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Immunopharmacology by Manzoor M. Khan Pdf

During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

Author : Richard K. Burt,Dominique Farge,Milton A. Ruiz,Riccardo Saccardi,John A. Snowden
Publisher : Unknown
Page : 666 pages
File Size : 40,5 Mb
Release : 2021-11
Category : Autoimmune diseases
ISBN : 1032065370

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Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases by Richard K. Burt,Dominique Farge,Milton A. Ruiz,Riccardo Saccardi,John A. Snowden Pdf

"This book summarizes the progress made across the international medical and scientific research communities towards the goal of converting a chronic autoimmune disease into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies to generate sustained immune tolerance"--

Author : Ross Cameron,George Feuer,Felix de la Iglesia
Publisher : Springer Science & Business Media
Page : 701 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642610134

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Drug-Induced Hepatotoxicity by Ross Cameron,George Feuer,Felix de la Iglesia Pdf

The advances in science and medicine we are now experiencing are unprec edented and exciting. Life expectancy is prolonged, and quality of life is much improved. We learn of fabulous new discoveries made at the bench or the bedside every week. Many diseases have been totally eliminated, others can be significantly improved by new therapeutic formulations. Much of the success can be attributed to a better understanding of disease processes and the specific targeting of new and more effective medications. As is the case in many areas of successful human endeavour, there can be a downside. In the case of drugs and chemicals it is their adverse effects which are of concern. Of course, every effort is made to devise medications that are safe, and the need to elucidate and understand mechanisms are crucial, yet adverse effects remain a problem. They can be unpredictable and diverse. Drugs have been shown to induce virtually the whole gamut of human liver pathology from acute fulminant hepatitis to chronic active hepatitis to cirrho sis and even malignancy. Hence the possibility of adverse drug effects must be considered in the differential diagnosis of many patients with liver disease. This is well recognized and is very important; indeed, removal of the offending agent can often lead to reversal of the adverse effect. This is an area of hepatology where we can really make a difference.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1628 pages
File Size : 46,5 Mb
Release : 1993
Category : Medicine
ISBN : UOM:39015074107676

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Current Catalog by National Library of Medicine (U.S.) Pdf

First multi-year cumulation covers six years: 1965-70.

Author : Anonim
Publisher : Academic Press
Page : 426 pages
File Size : 52,9 Mb
Release : 1996-05-09
Category : Medical
ISBN : 9780080581279

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Advances in Pharmacology by Anonim Pdf

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1752 pages
File Size : 42,8 Mb
Release : 1987
Category : Medicine
ISBN : MINN:31951M01375432K

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National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : Kim D. Rainsford
Publisher : CRC Press
Page : 254 pages
File Size : 55,5 Mb
Release : 1995-12-11
Category : Medical
ISBN : 0849349370

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Advances in Anti Rheumatic Therapy by Kim D. Rainsford Pdf

This work on advances in anti-rheumatic therapy covers topics such as: outcome measures in clinical trials of anti-rheumatic drugs; azapropazone (AZP); the mode of action of glucocorticoids; and clinical trials of oral chondroitin sulphate in the treatment of osteoarthritis.

Author : Robert B. Nussenblatt,Scott M. Whitcup
Publisher : Elsevier Health Sciences
Page : 449 pages
File Size : 47,9 Mb
Release : 2010-04-06
Category : Medical
ISBN : 9780323084017

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Uveitis E-Book by Robert B. Nussenblatt,Scott M. Whitcup Pdf

Uveitis is the comprehensive reference you need for a balanced approach to basic science and clinical application. Robert B. Nussenblatt and Scott M. Whitcup provide a cohesive and integrated discussion of the topic, covering everything from the role of surgery to AIDS to anterior uveitis and more. This new edition even includes full color throughout with 400 photographs and illustrations. Comprehensive yet readable, this resource packs everything you need in patient evaluation and management to achieve optimal results. Covers the medical, pharmacological, and surgical treatment of uveitis to serve as a complete overview of all uveitis related information. Features multiple chapters on diagnostic approach to help you overcome challenges in making accurate diagnoses. Provides additional information on inflammatory eye diseases in chapters on scleritis, masquerade syndromes, and the role of inflammation in other ocular diseases for more comprehensive coverage. Includes illustrated case studies to supplement major clinical points and provide insight into real situations that you can apply in practice. Highlights important information in key points boxes that make it easy to locate crucial points on each topic. Includes access to the fully searchable text online at expertconsult.com. Features significant updates to the chapters on the role of surgery in the patient with uveitis, acquired immune deficiency syndrome, anterior uveitis, white dot syndromes, and masquerade syndromes. Covers advancements and new developments on all aspects of uveitis including new medical and surgical treatments. Presents photographs in full color to better prepare you for actual clinical diagnosis.

Author : H Dean Jack
Publisher : CRC Press
Page : 788 pages
File Size : 46,9 Mb
Release : 1994-06-30
Category : Medical
ISBN : 0781702194

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Immunotoxicology And Immunopharmacology by H Dean Jack Pdf

The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.

Author : Frans P. Nijkamp,Michael Parnham
Publisher : Springer Science & Business Media
Page : 659 pages
File Size : 51,8 Mb
Release : 2006-04-04
Category : Medical
ISBN : 9783764374082

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Principles of Immunopharmacology by Frans P. Nijkamp,Michael Parnham Pdf

The rapid developments in immunology in recent immunomodulatory drugs can be distinguished years have dramatically expanded our knowledge of from their beneficial therapeutic effects. mammalian host defence mechanisms. The molecu- Currently,it is only possible to obtain an overview lar mechanisms of cellular interactions during of these various aspects of immunopharmacology immune responses have been unravelled,the intra- by reading a range of immunological,pharmacol- cellular responses involved in signal transduction ical,diagnostic and toxicological literature. Good delineated and an ever-increasing number of soluble immunological textbooks are available, while mediators of immune and inflammatory reponses immunopharmacology is covered mainly in terms of have been discovered. the inflammatory response. Principles of Immuno- The initial result of this explosion of knowledge pharmacology is intended to provide for the first time has been to provide the researcher and the clinician in a single volume a basic understanding of with an arsenal of diagnostic tools with which the immunological mechanisms,a review of important immunological bases of disease processes can be immunodiagnostic tools and a description of the investigated. This has made disease diagnosis much main pharmacological agents which modify the more precise,enabling the physician to tailor therapy immune response,together with an introduction to much more closely to the individual patient’s needs. immunotoxicology. As such we hope that it will be However,better understanding of disease processes useful as a reference text for physicians,researchers only provides a gradual improvement in therapy. This and students with a rudimentary knowledge of is because the new molecular targets that have been immunology.

Author : Roland Seifert
Publisher : Springer
Page : 487 pages
File Size : 50,7 Mb
Release : 2019-07-19
Category : Medical
ISBN : 9783030188993

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Basic Knowledge of Pharmacology by Roland Seifert Pdf

This is the perfect pharmacology textbook for medical and pharmacy students. The book was developed on the +30-year experience of the author as pharmacology professor in the United States and Germany. The book discusses the most important drugs (400) in the context of relevant diseases. Summary tables and schemes, MCQ exam questions, case studies and a list of drugs aid memorization of the material before an exam. All chapters are written in the same concise style and use a modern and precise pharmacological nomenclature. After reading of the book, the student will be able to critically assess the proper use of the most important drugs and advise patients properly. The didactic concept of the book has been developed on the author’s own pharmacology courses for which he has received numerous teaching awards. The book takes advantage of the learning spiral, in which material is presented repeatedly from various angles. This book is an adaptation for an international audience of the German textbook “Basiswissen Pharmakologie” (2018); ISBN: 978-3-662-56303-8.

Author : Anonim
Publisher : Unknown
Page : 1808 pages
File Size : 49,7 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864948

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Cumulated Index Medicus by Anonim Pdf