Implementing Precision Medicine In Best Practices Of Chronic Airway Diseases

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Implementing Precision Medicine in Best Practices of Chronic Airway Diseases

Ioana Agache,Peter Hellings

Author : Ioana Agache,Peter Hellings
Publisher : Academic Press
Page : 228 pages
File Size : 55,9 Mb
Release : 2018-09-19
Category : Medical
ISBN : 9780128134726

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Implementing Precision Medicine in Best Practices of Chronic Airway Diseases by Ioana Agache,Peter Hellings Pdf

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides a comprehensive overview of the application of precision medicine in airway diseases with a goal of promoting optimal control of disease, higher patient satisfaction and disease prevention. As medical research continues to fund this area, the book highlights the need for implementation of the principles of precision medicine into the bedside management of chronic airway diseases. It is clear that chronic airway diseases are heterogeneous and that a personalized approach is warranted whereby treatment is tailored to the level of the individual patient. Written for basic researchers, medical doctors and other healthcare practitioners this book provides guidance on the implementation of the principles of precision medicine into further research and daily clinical practice. Bridges the gap between precision medicine research and the implementation of the principles into daily clinical practice Includes contributions from key opinion leaders in the field of airway disease giving a worldwide perspective Discusses precision medicine in terms of personalized and stratified medicine, biomarkers, prediction of success, participation of the patient and prevention of disease

Severe Asthma

Kian Fan Chung,Elliot Israel,Peter G. Gibson

Author : Kian Fan Chung,Elliot Israel,Peter G. Gibson
Publisher : European Respiratory Society
Page : 360 pages
File Size : 48,7 Mb
Release : 2019-06-01
Category : Medical
ISBN : 9781849841047

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Severe Asthma by Kian Fan Chung,Elliot Israel,Peter G. Gibson Pdf

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Data Protection and Privacy in Healthcare

Ahmed Elngar,Ambika Pawar,Prathamesh Churi

Author : Ahmed Elngar,Ambika Pawar,Prathamesh Churi
Publisher : CRC Press
Page : 188 pages
File Size : 45,5 Mb
Release : 2021-03-10
Category : Technology & Engineering
ISBN : 9781000349351

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Data Protection and Privacy in Healthcare by Ahmed Elngar,Ambika Pawar,Prathamesh Churi Pdf

The Healthcare industry is one of the largest and rapidly developing industries. Over the last few years, healthcare management is changing from disease centered to patient centered. While on one side the analysis of healthcare data plays an important role in healthcare management, but on the other side the privacy of a patient’s record must be of equal concern. This book uses a research-oriented approach and focuses on privacy-based healthcare tools and technologies. It offers details on privacy laws with real-life case studies and examples, and addresses privacy issues in newer technologies such as Cloud, Big Data, and IoT. It discusses the e-health system and preserving its privacy, and the use of wearable technologies for patient monitoring, data streaming and sharing, and use of data analysis to provide various health services. This book is written for research scholars, academicians working in healthcare and data privacy domains, as well as researchers involved with healthcare law, and those working at facilities in security and privacy domains. Students and industry professionals, as well as medical practitioners might also find this book of interest.

Controversies in COPD

Antonio Anzueto,Yvonne Heijdra,John R. Hurst

Author : Antonio Anzueto,Yvonne Heijdra,John R. Hurst
Publisher : European Respiratory Society
Page : 336 pages
File Size : 52,6 Mb
Release : 2015-09-01
Category : Medical
ISBN : 9781849840644

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Controversies in COPD by Antonio Anzueto,Yvonne Heijdra,John R. Hurst Pdf

Edited by Antonio Anzueto, Yvonne Heijdra and John R. Hurst COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard

Respiratory Muscles in Chronic Obstructive Pulmonary Disease

A. Grassino,C. Fracchia,C. Rampulla,L. Zocchi

Author : A. Grassino,C. Fracchia,C. Rampulla,L. Zocchi
Publisher : Springer Science & Business Media
Page : 177 pages
File Size : 48,5 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9781447138501

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Respiratory Muscles in Chronic Obstructive Pulmonary Disease by A. Grassino,C. Fracchia,C. Rampulla,L. Zocchi Pdf

While emphysema and chronic bronchitis are primarily lung di seases, one of their major consequences is to deeply affect the function of the respiratory muscles. Lung hyperinflation shortens the inspiratory muscles due to increased airways resistance, more of their effort is demanded and changes in nutritional status wea ken them further. Their malfunction can lead to severe dyspnea and to failure of the ventilatory pump. Over the last 10 years we have witnessed an explosion of information of how respiratory muscles function in health and disease, new techniques for their evaluation have been created, the concept of fatigue, weakness, and failure was developed, and their rest or training was attemp ted. The implication of respiratory muscles malfunction in respi ratory medicine has reached a prominent place. It seems remarkable that while some aspect of skeletal muscles function requires molecular biology techniques to find new an swers, we still know little on respiratory muscles interaction, stra tegies of coordination, their role in dyspnea, chronic hypercapnia or how to effectively improve their function in patients. This workshop was organized and held at the Medical Center of Rehabilitation in Montescano and represents an attempt to focus on how the newly adquired wealth of information can eventually be trasformed into medical care. The particpants in this workshop brought forward challenging thoughts and we are most grateful for their participation. This book represents a report of the proceedings and also provides the most updated information in this field.

The Fourth Industrial Revolution

Klaus Schwab

Author : Klaus Schwab
Publisher : Currency
Page : 192 pages
File Size : 54,5 Mb
Release : 2017-01-03
Category : Business & Economics
ISBN : 9781524758875

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The Fourth Industrial Revolution by Klaus Schwab Pdf

World-renowned economist Klaus Schwab, Founder and Executive Chairman of the World Economic Forum, explains that we have an opportunity to shape the fourth industrial revolution, which will fundamentally alter how we live and work. Schwab argues that this revolution is different in scale, scope and complexity from any that have come before. Characterized by a range of new technologies that are fusing the physical, digital and biological worlds, the developments are affecting all disciplines, economies, industries and governments, and even challenging ideas about what it means to be human. Artificial intelligence is already all around us, from supercomputers, drones and virtual assistants to 3D printing, DNA sequencing, smart thermostats, wearable sensors and microchips smaller than a grain of sand. But this is just the beginning: nanomaterials 200 times stronger than steel and a million times thinner than a strand of hair and the first transplant of a 3D printed liver are already in development. Imagine “smart factories” in which global systems of manufacturing are coordinated virtually, or implantable mobile phones made of biosynthetic materials. The fourth industrial revolution, says Schwab, is more significant, and its ramifications more profound, than in any prior period of human history. He outlines the key technologies driving this revolution and discusses the major impacts expected on government, business, civil society and individuals. Schwab also offers bold ideas on how to harness these changes and shape a better future—one in which technology empowers people rather than replaces them; progress serves society rather than disrupts it; and in which innovators respect moral and ethical boundaries rather than cross them. We all have the opportunity to contribute to developing new frameworks that advance progress.

Handbook of Biomarkers and Precision Medicine

Claudio Carini,Mark Fidock,Alain van Gool

Author : Claudio Carini,Mark Fidock,Alain van Gool
Publisher : CRC Press
Page : 1025 pages
File Size : 53,8 Mb
Release : 2019-04-16
Category : Mathematics
ISBN : 9780429574627

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Handbook of Biomarkers and Precision Medicine by Claudio Carini,Mark Fidock,Alain van Gool Pdf

"The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work." -Maria Freire, Foundation for the National Institutes of Health Handbook of Biomarkers and Precision Medicine provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development. Features: Detailed insights into biomarker discovery, validation and diagnostic development with implementation strategies Lessons-learned from successful Precision Medicine case studies A variety of exciting and emerging biomarker technologies The next frontiers and future challenges of biomarkers in Precision Medicine Claudio Carini, Mark Fidock and Alain van Gool are internationally recognized as scientific leaders in Biomarkers and Precision Medicine. They have worked for decades in academia and pharmaceutical industry in EU, USA and Asia. Currently, Dr. Carini is Honorary Faculty at Kings’s College School of Medicine, London, UK. Dr. Fidock is Vice President of Precision Medicine Laboratories at AstraZeneca, Cambridge, UK. Prof.dr. van Gool is Head Translational Metabolic Laboratory at Radboud university medical school, Nijmegen, NL.

Multidisciplinary Perspectives on Artificial Intelligence and the Law

Henrique Sousa Antunes,Pedro Miguel Freitas,Arlindo L. Oliveira,Clara Martins Pereira,Elsa Vaz de Sequeira,Luís Barreto Xavier

Author : Henrique Sousa Antunes,Pedro Miguel Freitas,Arlindo L. Oliveira,Clara Martins Pereira,Elsa Vaz de Sequeira,Luís Barreto Xavier
Publisher : Springer Nature
Page : 457 pages
File Size : 55,7 Mb
Release : 2023-12-26
Category : Law
ISBN : 9783031412646

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Multidisciplinary Perspectives on Artificial Intelligence and the Law by Henrique Sousa Antunes,Pedro Miguel Freitas,Arlindo L. Oliveira,Clara Martins Pereira,Elsa Vaz de Sequeira,Luís Barreto Xavier Pdf

This open access book presents an interdisciplinary, multi-authored, edited collection of chapters on Artificial Intelligence (‘AI’) and the Law. AI technology has come to play a central role in the modern data economy. Through a combination of increased computing power, the growing availability of data and the advancement of algorithms, AI has now become an umbrella term for some of the most transformational technological breakthroughs of this age. The importance of AI stems from both the opportunities that it offers and the challenges that it entails. While AI applications hold the promise of economic growth and efficiency gains, they also create significant risks and uncertainty. The potential and perils of AI have thus come to dominate modern discussions of technology and ethics – and although AI was initially allowed to largely develop without guidelines or rules, few would deny that the law is set to play a fundamental role in shaping the future of AI.As the debate over AI is far from over, the need for rigorous analysis has never been greater. This book thus brings together contributors from different fields and backgrounds to explore how the law might provide answers to some of the most pressing questions raised by AI. An outcome of the Católica Research Centre for the Future of Law and its interdisciplinary working group on Law and Artificial Intelligence, it includes contributions by leading scholars in the fields of technology, ethics and the law.

Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention

Claudia Traidl-Hoffmann,Torsten Zuberbier,Thomas Werfel

Author : Claudia Traidl-Hoffmann,Torsten Zuberbier,Thomas Werfel
Publisher : Springer Nature
Page : 489 pages
File Size : 41,8 Mb
Release : 2021-11-21
Category : Medical
ISBN : 9783030840488

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Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention by Claudia Traidl-Hoffmann,Torsten Zuberbier,Thomas Werfel Pdf

Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.

Global Surveillance, Prevention and Control of Chronic Respiratory Diseases

World Health Organization

Author : World Health Organization
Publisher : World Health Organization
Page : 156 pages
File Size : 50,6 Mb
Release : 2007
Category : Chronic diseases
ISBN : 9789241563468

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Global Surveillance, Prevention and Control of Chronic Respiratory Diseases by World Health Organization Pdf

Chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease, kill more than 4 million people every year, and affect hundreds of millions more. These diseases erode the health and well-being of the patients and have a negative impact on families and societies. This report raises awareness of the huge impact of chronic respiratory diseases worldwide, and highlights the risk factors as well as ways to prevent and treat these diseases.

Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis

Graham A. W. Rook,Christopher A. Lowry

Author : Graham A. W. Rook,Christopher A. Lowry
Publisher : Springer Nature
Page : 421 pages
File Size : 49,5 Mb
Release : 2022-03-24
Category : Medical
ISBN : 9783030910518

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Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis by Graham A. W. Rook,Christopher A. Lowry Pdf

This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the “hygiene hypothesis” by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.

Respiratory Muscle Strength Training

Christine Sapienza, Bari Hoffman

Author : Christine Sapienza, Bari Hoffman
Publisher : Plural Publishing
Page : 302 pages
File Size : 48,9 Mb
Release : 2020-12-18
Category : Medical
ISBN : 9781635502602

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Respiratory Muscle Strength Training by Christine Sapienza, Bari Hoffman Pdf

Respiratory Muscle Strength Training is a clinical guide, intended to provide clinicians with the background information they need to understand respiratory muscle strength training (RMST). With a variety of case studies provided by well-known authors and clinicians, this text acts as a guidebook to the RMST protocol and provides practical information for use in the field of healthcare. In addition to real-world case studies, Respiratory Muscle Strength Training includes a chapter devoted to Frequently Asked Questions, a representative sample of the devices commonly used for respiratory training, and instructions for using them in patient care.

Disease Control Priorities, Third Edition (Volume 6)

King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 40,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Update in Immunotherapy for Aeroallergens, Foods, and Venoms, An Issue of Immunology and Allergy Clinics of North America E-Book

Linda S. Coz,Anna H. Nowak-Wegrzyn

Author : Linda S. Coz,Anna H. Nowak-Wegrzyn
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 55,9 Mb
Release : 2019-12-03
Category : Medical
ISBN : 9780323718554

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Update in Immunotherapy for Aeroallergens, Foods, and Venoms, An Issue of Immunology and Allergy Clinics of North America E-Book by Linda S. Coz,Anna H. Nowak-Wegrzyn Pdf

This issue of Immunology and Allergy Clinics, guest edited by Drs. Linda S. Cox and Anna Nowak-Wegrzyn, is devoted to Immunotherapy for Aeroallergens, Foods, and Venoms. Articles in this issue include: Mechanism of Immunotherapy: Focus SCIT and SLIT; Subcutaneous Immunotherapy Safety: Incidence per surveys and risk factors; Sublingual Immunotherapy for Other Indications: Venom large local, latex, atopic dermatitis and food; Questions and Controversies regarding venom immunotherapy; Socioeconomics or Comparative Effectiveness of Immunotherapy; Risk Reduction in Peanut Immunotherapy; Food OIT with Adjuvants; Peanut OIT: State of the art; Evolution of Immune Responses in Food Immunotherapy; Safety of Food Oral Immunotherapy: What we know and what we need to learn; Novel Vaccines for Food Allergy; IgG and IgE in Food Allergy - What’s the connection?; and Sublingual and Patch Immunotherapy for Food Allergy.

Omics for Personalized Medicine

Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly

Author : Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly
Publisher : Springer Science & Business Media
Page : 832 pages
File Size : 42,9 Mb
Release : 2013-10-14
Category : Medical
ISBN : 9788132211846

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Omics for Personalized Medicine by Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly Pdf

“Omics for Personalized Medicine” will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.

Implementing Precision Medicine In Best Practices Of Chronic Airway Diseases

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases by Ioana Agache,Peter Hellings Pdf

Severe Asthma by Kian Fan Chung,Elliot Israel,Peter G. Gibson Pdf

Data Protection and Privacy in Healthcare by Ahmed Elngar,Ambika Pawar,Prathamesh Churi Pdf

Controversies in COPD by Antonio Anzueto,Yvonne Heijdra,John R. Hurst Pdf

Respiratory Muscles in Chronic Obstructive Pulmonary Disease by A. Grassino,C. Fracchia,C. Rampulla,L. Zocchi Pdf

The Fourth Industrial Revolution by Klaus Schwab Pdf

Handbook of Biomarkers and Precision Medicine by Claudio Carini,Mark Fidock,Alain van Gool Pdf

Multidisciplinary Perspectives on Artificial Intelligence and the Law by Henrique Sousa Antunes,Pedro Miguel Freitas,Arlindo L. Oliveira,Clara Martins Pereira,Elsa Vaz de Sequeira,Luís Barreto Xavier Pdf

Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention by Claudia Traidl-Hoffmann,Torsten Zuberbier,Thomas Werfel Pdf

Global Surveillance, Prevention and Control of Chronic Respiratory Diseases by World Health Organization Pdf

Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis by Graham A. W. Rook,Christopher A. Lowry Pdf

Respiratory Muscle Strength Training by Christine Sapienza, Bari Hoffman Pdf

Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Update in Immunotherapy for Aeroallergens, Foods, and Venoms, An Issue of Immunology and Allergy Clinics of North America E-Book by Linda S. Coz,Anna H. Nowak-Wegrzyn Pdf

Omics for Personalized Medicine by Debmalya Barh,Dipali Dhawan,Nirmal Kumar Ganguly Pdf

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