Induced Pluripotent Stem Ips Cells

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Induced Pluripotent Stem (iPS) Cells

Andras Nagy,Kursad Turksen
Induced Pluripotent Stem iPS Cells Book PDF

Author : Andras Nagy,Kursad Turksen
Publisher : Springer Nature
Page : 829 pages
File Size : 54,6 Mb
Release : 2022-06-22
Category : Science
ISBN : 9781071621196

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Induced Pluripotent Stem (iPS) Cells by Andras Nagy,Kursad Turksen Pdf

This extensive new edition presents protocols reflecting the great strides made in the study of induced pluripotent stem (iPS) cells. The collection explores new and improved methods for the generation, expansion, and maintenance of iPS cells from different tissue types, characterization of their differentiation pathways along different lineages, and their potential utility in tissue repair and regeneration. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, Second Edition aims to arm stem cell biologists, both novice and expert, with invaluable protocols that are currently being used in various laboratories around the world.

Induced Pluripotent Stem Cells and Human Disease

Kursad Turksen
Induced Pluripotent Stem Cells and Human Disease Book PDF

Author : Kursad Turksen
Publisher : Springer Nature
Page : 426 pages
File Size : 53,9 Mb
Release : 2022-07-02
Category : Science
ISBN : 9781071625859

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Induced Pluripotent Stem Cells and Human Disease by Kursad Turksen Pdf

This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models. Reflecting the latest technology for generating induced pluripotent stem cells (iPS cells) and their initial characterization, the book explores techniques invaluable both for studies of disease-specific cell types and for their potential applications in regenerative medicine. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Induced Pluripotent Stem Cells and Human Disease: Methods and Protocols serves as a vital guide that is valuable for not only experts but also novices in the stem cell field.

Pluripotent Stem Cells

Deepa Bhartiya,Nibedita Lenka
Pluripotent Stem Cells Book PDF

Author : Deepa Bhartiya,Nibedita Lenka
Publisher : BoD – Books on Demand
Page : 642 pages
File Size : 42,7 Mb
Release : 2013-08-28
Category : Science
ISBN : 9789535111924

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Pluripotent Stem Cells by Deepa Bhartiya,Nibedita Lenka Pdf

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.

Induced Pluripotent Stem Cells

Sibel Yildirim
Induced Pluripotent Stem Cells Book PDF

Author : Sibel Yildirim
Publisher : Springer Science & Business Media
Page : 76 pages
File Size : 49,8 Mb
Release : 2012-02-02
Category : Science
ISBN : 9781461422068

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Induced Pluripotent Stem Cells by Sibel Yildirim Pdf

Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed so that they return to their embryonic state. It is not yet known if iPS stem cells and embryonic stem cells differ significantly. Today many fundamental belief systems in biology are shifting towards accepting that mature body cells can be reverted to an embryonic state without the help of eggs or embryos. With their changed identities, iPS cells are then ready to serve as new tools for research in the fields of disease pathogenesis, drug discovery, oncology, and cell transplantation. One example of this would be using iPS from a patient’s mature cells to repair damaged tissue; it is thought that there would be very low incidence of rejection of the ‘new’ tissue in these cases. For the last four years, this therapeutic promise has been studied by hundreds of researchers worldwide in an effort to understand the ability of these cells to reverse their biological clocks.

Human Embryonic and Induced Pluripotent Stem Cells

Kaiming Ye,Sha Jin
Human Embryonic and Induced Pluripotent Stem Cells Book PDF

Author : Kaiming Ye,Sha Jin
Publisher : Humana Press
Page : 486 pages
File Size : 54,9 Mb
Release : 2016-08-23
Category : Science
ISBN : 1493958933

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Human Embryonic and Induced Pluripotent Stem Cells by Kaiming Ye,Sha Jin Pdf

Because of the huge potential of human embryonic stem (hES) cells, especially the newly developed human induced pluripotent stem (hiPS) cells, in disease treatment and life quality improvement, enormous efforts have been made to develop new methodologies to translate lab discoveries in stem cell research into bed-side clinical technologies. In Human Embryonic and Induced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols, experts in the field present a comprehensive collection of protocols designed for labs around the world. The topics covered in this detailed volume include techniques used for maintenance of hES and iPS cells in either small or large scale, techniques for directing hES and iPS cell lineage specification, techniques for enhancing the maturity of differentiated hES and iPS cells within three-dimensional scaffolds, techniques for reprogramming adult cells into iPS cells, techniques for generating patient-specific iPS cells, and techniques for translating hES and iPS cell research into new therapies. Chapters include lab ready protocols with tips on troubleshooting and avoiding known pitfalls. Wide-ranging and authoritative, Human Embryonic and Induced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols will be a tremendous aid for researchers and students who wish to explore these areas and transform their discoveries into the next generation of regenerative medicine and tissue engineering technologies.

Human Embryonic Stem Cells

Arlene Chiu,Mahendra S. Rao
Human Embryonic Stem Cells Book PDF

Author : Arlene Chiu,Mahendra S. Rao
Publisher : Springer Science & Business Media
Page : 455 pages
File Size : 44,5 Mb
Release : 2003-08-01
Category : Science
ISBN : 9781592594238

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Human Embryonic Stem Cells by Arlene Chiu,Mahendra S. Rao Pdf

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Medical Applications of iPS Cells

Haruhisa Inoue,Yukio Nakamura
Medical Applications of iPS Cells Book PDF

Author : Haruhisa Inoue,Yukio Nakamura
Publisher : Springer
Page : 190 pages
File Size : 52,5 Mb
Release : 2019-04-01
Category : Medical
ISBN : 9789811336720

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Medical Applications of iPS Cells by Haruhisa Inoue,Yukio Nakamura Pdf

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.

Induced Stem Cells

Patrick Joseph Sullivan,Elena K. Mortensen
Induced Stem Cells Book PDF

Author : Patrick Joseph Sullivan,Elena K. Mortensen
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 40,6 Mb
Release : 2011
Category : Stem cells
ISBN : 1613246137

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Induced Stem Cells by Patrick Joseph Sullivan,Elena K. Mortensen Pdf

Induced pluripotent stem (iPS) cell technology has paved new ways for disease modelling and drug discovery. Disease modelling with the differentiated neuronal cells from patient-specific iPS cells partially recapitulated the phenotypes of spinal muscular atrophy, familial dysautonomia and Rett syndrome. In this book, the authors present current research in the study of induced stem cells, including the cryopreservation of pluipotent stem cells; tissue engineering approaches using bioactive ceramics towards bone regeneration; induced pluripotent stem cell-derived hepatocytes as an alternative to human adult hepatocytes; iPS technology for studying neurodegenerative diseases and iPS from cord blood cells.

Patient-Specific Induced Pluripotent Stem Cell Models

Andras Nagy,Kursad Andras,Kursad Turksen
Patient Specific Induced Pluripotent Stem Cell Models Book PDF

Author : Andras Nagy,Kursad Andras,Kursad Turksen
Publisher : Unknown
Page : 368 pages
File Size : 40,7 Mb
Release : 2016
Category : Cytology
ISBN : 1493930346

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Patient-Specific Induced Pluripotent Stem Cell Models by Andras Nagy,Kursad Andras,Kursad Turksen Pdf

This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases. Specifically, representative protocols on various disease models have been collected from labs around the world. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization is an ideal reference for scientists working on furthering iPS research.

Induced Pluripotent Stem Cells in Brain Diseases

Vivi M. Heine,Stephanie Dooves,Dwayne Holmes,Judith Wagner
Induced Pluripotent Stem Cells in Brain Diseases Book PDF

Author : Vivi M. Heine,Stephanie Dooves,Dwayne Holmes,Judith Wagner
Publisher : Springer Science & Business Media
Page : 69 pages
File Size : 48,6 Mb
Release : 2011-11-23
Category : Science
ISBN : 9789400728165

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Induced Pluripotent Stem Cells in Brain Diseases by Vivi M. Heine,Stephanie Dooves,Dwayne Holmes,Judith Wagner Pdf

Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).​

Human Pluripotent Stem Cells

Uma Lakshmipathy,Chad C. MacArthur,Mahalakshmi Sridharan,Rene H. Quintanilla
Human Pluripotent Stem Cells Book PDF

Author : Uma Lakshmipathy,Chad C. MacArthur,Mahalakshmi Sridharan,Rene H. Quintanilla
Publisher : John Wiley & Sons
Page : 175 pages
File Size : 47,6 Mb
Release : 2018-02-13
Category : Science
ISBN : 9781119394334

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Human Pluripotent Stem Cells by Uma Lakshmipathy,Chad C. MacArthur,Mahalakshmi Sridharan,Rene H. Quintanilla Pdf

Comprehensive coverage of the entire induced pluripotent stem cell basic work flow Pluripotent stem cells (PSC) can divide indefinitely, self-renew, and can differentiate to functionally reconstitute almost any cell in the normal developmental pathway, given the right conditions. This comprehensive book, which was developed from a training course, covers all of the PSCs (embryonic, embryonic germ, and embryonic carcinoma) and their functions. It demonstrates the feeder-dependent and feeder-free culture of hESC and hiPSC, which will be referred to in all protocols as PSCs. It also addresses the methods commonly used to determine pluripotency, as defined by self-renewal marker expression and differentiation potential. Human Pluripotent Stem Cells: A Practical Guide offers in-depth chapter coverage of introduction to stem cell, PSC culture, reprogramming, differentiation, PSC characterization, and more. It also includes four appendixes containing information on reagents, medias, and solutions; common antibodies; consumable and equipment; and logs and forms. Includes helpful tips and tricks that are normally omitted from regular research papers Features useful images to support the technical aspects and results visually as well as diagrammatic illustrations Presents specific sections (ie: reprogramming, differentiation) in a concise and easily digestible manner Written by experts with extensive experience in stem cell technologies Human Pluripotent Stem Cells: A Practical Guide is an ideal text for stem cell researchers, including principal investigators, and others in university and industry settings, and for new graduate students in PSC labs.

CMBEBIH 2017

Almir Badnjevic
CMBEBIH 2017 Book PDF

Author : Almir Badnjevic
Publisher : Springer
Page : 806 pages
File Size : 51,6 Mb
Release : 2017-03-14
Category : Technology & Engineering
ISBN : 9789811041662

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CMBEBIH 2017 by Almir Badnjevic Pdf

This volume presents the proceedings of the International Conference on Medical and Biological Engineering held from 16 to 18 March 2017 in Sarajevo, Bosnia and Herzegovina. Focusing on the theme of ‘Pursuing innovation. Shaping the future’, it highlights the latest advancements in Biomedical Engineering and also presents the latest findings, innovative solutions and emerging challenges in this field. Topics include: - Biomedical Signal Processing - Biomedical Imaging and Image Processing - Biosensors and Bioinstrumentation - Bio-Micro/Nano Technologies - Biomaterials - Biomechanics, Robotics and Minimally Invasive Surgery - Cardiovascular, Respiratory and Endocrine Systems Engineering - Neural and Rehabilitation Engineering - Molecular, Cellular and Tissue Engineering - Bioinformatics and Computational Biology - Clinical Engineering and Health Technology Assessment - Health Informatics, E-Health and Telemedicine - Biomedical Engineering Education - Pharmaceutical Engineering

Engineering and Application of Pluripotent Stem Cells

Ulrich Martin,Robert Zweigerdt,Ina Gruh
Engineering and Application of Pluripotent Stem Cells Book PDF

Author : Ulrich Martin,Robert Zweigerdt,Ina Gruh
Publisher : Springer
Page : 228 pages
File Size : 49,8 Mb
Release : 2018-02-28
Category : Science
ISBN : 9783319735917

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Engineering and Application of Pluripotent Stem Cells by Ulrich Martin,Robert Zweigerdt,Ina Gruh Pdf

​This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening. This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research.

Atlas of Human Pluripotent Stem Cells in Culture

Lyn Healy,Ludmila Ruban
Atlas of Human Pluripotent Stem Cells in Culture Book PDF

Author : Lyn Healy,Ludmila Ruban
Publisher : Springer
Page : 216 pages
File Size : 50,5 Mb
Release : 2014-11-07
Category : Science
ISBN : 9781489975072

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Atlas of Human Pluripotent Stem Cells in Culture by Lyn Healy,Ludmila Ruban Pdf

This lavishly-illustrated, authoritative atlas explores the intricate art of culturing human pluripotent stem cells. Twelve chapters – containing more than 280 color illustrations – cover a variety of topics in pluripotent stem cell culturing including mouse and human fibroblasts, human embryonic stem cells and induced pluripotent stem cells, characteristic staining patterns, and abnormal cultures, among others. Atlas of Human Pluripotent Stem Cells in Culture is a comprehensive collection of illustrated techniques complemented by informative and educational captions examining what good quality cells look like and how they behave in various environments. Examples of perfect cultures are compared side-by-side to less-than-perfect and unacceptable examples of human embryonic and induced pluripotent stem cell colonies. This detailed and thorough atlas is an invaluable resource for researchers, teachers, and students who are interested in or working with stem cell culturing.

Interface Oral Health Science 2016

Keiichi Sasaki,Osamu Suzuki,Nobuhiro Takahashi
Interface Oral Health Science 2016 Book PDF

Author : Keiichi Sasaki,Osamu Suzuki,Nobuhiro Takahashi
Publisher : Unknown
Page : 272 pages
File Size : 48,9 Mb
Release : 2020-10-08
Category : Medical
ISBN : 1013267850

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Interface Oral Health Science 2016 by Keiichi Sasaki,Osamu Suzuki,Nobuhiro Takahashi Pdf

This volume broadens understanding of dentistry and promotes interdisciplinary research across a wide range of related fields, based on the symposium entitled "Innovative Research for Biosis-Abiosis Intelligent Interface 2016". It aims to create highly functional and autonomic intelligent interface by combining highly functional interface science with the technology of an evaluation and a control at the interface, with the various topics of biomaterials, innovation for oral science and application, regenerative oral science, and medical engineering. Since 2002, the Tohoku University Graduate School of Dentistry has hosted "Interface Oral Health Science" several times as the main theme of dental research in the twenty-first century, and this is the sixth proceedings of the symposiums following the ones in 2005, 2007, 2009, 2011, and 2014.This book benefits not only dental scientists but also other health scientists including medical physicians and pharmacologists, material scientists, engineers, and any scientist who is involved in variety of disciplines. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.