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Author : Charles N. Serhan,Peter A. Ward,Derek W. Gilroy Publisher : Cambridge University Press Page : 489 pages File Size : 40,6 Mb Release : 2010-04-26 Category : Medical ISBN : 9780521887298
Fundamentals of Inflammation by Charles N. Serhan,Peter A. Ward,Derek W. Gilroy Pdf
The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion.
Inflammation, 4 Volume Set by Jean-Marc Cavaillon,Mervyn Singer Pdf
The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.
Chronic Inflammation by Masayuki Miyasaka,Kiyoshi Takatsu Pdf
This book provides readers with the most up-to-date information on cutting-edge research concerning chronic inflammation. We now know that when inflammation becomes chronic, it acts as a strong disease-promoting factor in a variety of disorders including arteriosclerosis, obesity, cancer, and Alzheimer disease. Chronic inflammation is hence called as the “silent killer”; it upsets the body’s homeostatic mechanism insidiously. In spite of these developments, we know very little about the mechanism underlying chronic inflammation. Particularly, we do not know precisely what induces chronic inflammation or what promotes its prolongation in a spatiotemporal framework. Neither do we have clear knowledge about how chronic inflammation destroys various tissues or how it predisposes individuals to many different diseases. To make the situation worse, we have no effective treatment against chronic inflammation. Since 2010, two major research programs (CREST and PRESTO) aimed at clarifying the mechanisms underlying chronic inflammation were launched in Japan, and investigators of different research areas with a brilliant track record were selected by their research proposals. Subsequently they have made their best efforts to answer the conundrum concerning chronic inflammation. This book is a compendium of such research efforts. In each chapter, the CREST- or PRESTO-funded researchers summarize their original work concerning mechanisms of induction, progression, or resolution underlying chronic inflammation. The most emphasized characteristic is the molecular aspect of chronic inflammation. The book thus presents the most recent progress made in the molecular understanding of chronic inflammation.
Inflammation and the Microcirculation by D. Neil Granger,Elena Senchenkova Pdf
The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Meals That Heal Inflammation by Julie Daniluk, RHN Pdf
Did you know that virtually every health condition from asthma to irritable bowel syndrome is linked to inflammation? When inflammation gets out of control, the result is pain and discomfort—and it’s a phenomenon that’s on the rise. If you’re one of the millions of people who have been affected by allergies, diabetes, skin disorders, heart disease, arthritis, or any other condition ending in "-itis," then you know firsthand what havoc inflammation can cause. In Meals That Heal Inflammation, television personality and registered holistic nutritionist Julie Daniluk shows you how to conquer these health conditions with foods that will make you feel fantastic. This comprehensive book is packed with meals that can assist the body’s healing process—all while treating your taste buds to new and delicious flavors. The recipes, from healing teas to balanced meals and tempting desserts, are simple to make. Whether it’s the savory cranberry quinoa salad or the sumptuous key lime pie, every recipe in this book contains foods that naturally heal inflammation. Extensively researched and full of reference charts, diagnostic quizzes, food comparison lists, and the latest information about the healing properties of everyday foods, Meals That Heal Inflammation is an essential addition to every kitchen.
Intraocular Inflammation by Manfred Zierhut,Carlos Pavesio,Shigeaki Ohno,Fernando Orefice,Narsing A. Rao Pdf
This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.
The Inflammation Spectrum by Dr. Will Cole,Eve Adamson Pdf
From the international bestselling author of Ketotarian comes a revolutionary new plan to discover the foods your unique body loves, hates, and needs to feel great. In Dr. Will Cole's game-changing new book, readers will discover how inflammation is at the core of most common health woes. What's more, it exists on a continuum: from mild symptoms such as weight gain and fatigue on one end, to hormone imbalance and autoimmune conditions on the other. How you feel is being influenced by every meal. Every food you eat is either feeding inflammation or fighting it. Because no one else is you, the foods that work well for someone else may not be right for your body. At heart, The Inflammation Spectrum is about learning to love your body enough to nourish it with delicious, healing foods. You'll find insightful quizzes and empowering advice to put you on a path toward food freedom and overall healing, once and for all.
Author : Paul G. Winyard,Derek A. Willoughby Publisher : Springer Science & Business Media Page : 373 pages File Size : 49,5 Mb Release : 2008-02-03 Category : Medical ISBN : 9781592593743
Inflammation Protocols by Paul G. Winyard,Derek A. Willoughby Pdf
Inflammation has been described as the basis of many pathologies of human disease. When one considers the updated signs of inflammation, they would be vasodilation, cell migration, and, in the case of chronic inflam- tion, cell proliferation, often with an underlying autoimmune basis. Gen- ally, inflammation may be divided into acute, chronic, and autoimmune, - though the editors believe that most, if not all, chronic states are often the result of an autoimmune response to an endogenous antigen. Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well. The lack of advances in classical inflammatory diseases, such as rh- matoid arthritis, may in part arise from a failure to classify the disease into different forms. That different forms exist is exemplified in patients with d- fering responses to existing antiinflammatory drugs, ranging from nonresponders to very positive responders for a particular nonsteroidal an- inflammatory drug (NSAID). Though researchers have progressively unr- eled the mechanisms, the story is far from complete. It should also be noted that the inflammatory response is part of the innate immune response, or to use John Hunter’s words in 1795, “inflammation is a salutary response.” That may be applied in particular to the defensive response to invading micro- ganisms.
The Anti-Inflammation Diet and Recipe Book by Jessica K. Black Pdf
Recently, the connection between inflammation and heart disease, arthritis, and other chronic diseases has become established. Many food allergies inefficiently and overabundantly stimulate the immune system to react and cause inflammatory responses. Any inflammation in the body interferes with and slows down metabolism and the healing response. Chronic inflammation within our bodies erodes our wellness and paves the path for ill health. What is an anti-inflammatory diet? It eliminates many common allergenic foods that may promote inflammation in the body and reduces intake of pesticides, hormones, and antibiotic residues. The diet is full of whole foods, eliminates processed foods, sugars, and other man-made foods such as hydrogenated oils, and encourages ample vegetable intake for essential nutrients. The anti-inflammatory diet therefore promotes simpler and easier digestion and offers less insult on the body by reducing intake of toxins and other difficult to digest foods. If the blood and lymph are properly supplied and difficult to digest or assimilate foods are eliminated, cellular function, or in other words, metabolism, improves. Therefore the body is supported in such a way as to facilitate cellular regeneration and not cellular degeneration which may promote disease. The author, a naturopathic doctor, has helped many people on their way back to health with this anti-inflammatory diet. THE ANTI-INFLAMMATORY DIET AND RECIPE BOOK is the first book to give the complete program with specifics on how to eat and cook in order to prevent and counter inflammation. The purpose of the book is to act as a guide to help people learn to cook healthily. The first part of the book explains the benefits of the anti-inflammatory diet, gives the science. The second half of the book contains 108 recipes. Many of the recipes can be used as a template for even greater meals. The author offers many substitution suggestions and includes healthy tips with each of the recipes. Most of the recipes take very little time to fix. A week's sample menu for summer months and another for winter months is included as well as a substitutions chart, so that you can modify your favorite recipes to make them more healthy. This is a book for every healthy kitchen.
This second edition volume expands on the previous edition with an update on the broad spectrum of research models, techniques, and protocols used in laboratories by basic and clinical researchers. The chapters in this book are divided into two parts. Part One discusses the latest findings on the development and characterization of representative research models for chronic immune-based diseases and inflammation-associated cancers. Part Two covers biochemical, molecular, and cellular biological techniques that are commonly used to dissect the molecular mechanisms and cellular processes that drive the pathogenesis of certain disease states. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Inflammation and Cancer: Methods and Protocols, Second Edition is a valuable resource for those with a diverse range of laboratory-based experience, ranging from novice undergraduate students to established basic or clinical researchers who wish to diversify their existing portfolio of practical knowledge in the field.
This book covers the physiological processes relevant to inflammation. It centers on the recruitment of leukocytes to sites of injury and infection, their function in the tissue and the eventual resolution of inflammation.
Chosen by SELF Magazine as one of "7 Fascinating And Illuminating Books That Will Totally Open Your Eyes About Your Health" Both absorbing and revelatory, INFLAMED isn't just a story of healing (of an inflammatory, autoimmune condition). It's a crystal clear guide that cuts through the confusion and contradiction, offering an anti-inflammatory roadmap to reduce pain, calm chronic symptoms, and light a path to glowing, vibrant health. Whether your personal health simply feels slightly off, or you're experiencing a serious chronic illness, conventional care alone may not be getting you the results you want. Are you experiencing issues like fatigue, poor mood, resistant weight loss, aching joints, digestive upset or skin problems? INFLAMED is your concise guide to changing your life by reducing inflammation. A refreshing voice for readers who appreciate Western medicine, but who are searching for treatments that solve the root cause of their conditions - not just address them with a quick, pharmacological fix - Shelly Malone is the discerning expert chronic sufferers have been waiting for. Inside, readers will find: Exactly what inflammation means and how it manifests (including pain, allergies, infertility, depression, obesity and autoimmune conditions) The complete story on gluten, dairy and other food sensitivities The role your genes do and don't play in disease What your digestive tract is trying to tell you Why it's time to trade the calorie and fat gram counting for brand new eating principles Where inflammatory toxins hide (in your food, in your home and on your body) The synergistic connection between stress, sleep and hormones How your past medical history could be contributing to your poor health INFLAMED closes with a customizable, 25-step action plan the meets you where you are and provides over 20 guides from meal/snack ideas to product label guides to "lesser evils," a chart of delicious (and realistic) food substitutions. Lifestyle change can be intimidating. Learn how to get started with small, specific action steps for consistent progress - and better health. Find a reason - and a way - to live a healthy, vibrant life. www.inflamedbook.com
Imaging of Inflammation and Infection in Cardiovascular Diseases by Federico Caobelli Pdf
This book addresses the most relevant imaging techniques in order to detect inflammation and infection in the most common cardiovascular diseases. The book presents data concerning molecular imaging (SPECT and PET) and cardiac magnetic resonance imaging (MRI) for each disease, with a special focus on the emerging role of hybrid PET/MR imaging. Different non-ischemic and ischemic diseases as well as cardiac infections are addressed in detail; these include: Cardiac sarcoidosis, Cardiac amyloidosis, the vulnerable plaque, Post-infarction inflammatory alterations, Pericarditis, Myocarditis, Cardiac devices infections, and Endocarditis. The book also provides a comprehensive discussion on new targets and new tracers, to date mostly investigated at a pre-clinical stage, thus constituting an excellent basis for translational imaging. Imaging of Inflammation and Infection in Cardiovascular Diseases will be of interest not only for experts in clinical imaging, but also pre-clinical scientists and will be invaluable for both nuclear medicine physicians and radiologists.
The Everything Anti-Inflammation Diet Book by Karlyn Grimes Pdf
Olive oil protects your heart. Mushrooms fight free radicals. Ginger can combat rheumatoid arthritis Why live with chronic pain when the remedy can be as simple as changing the foods you eat? Diets high in processed, fatty, and sugary foods are the main cause of chronic inflammation, which wreaks havoc on your body and contributes to heart disease, diabetes, Alzheimer's--and even cancer. But with this easy-to-use guide, you will learn how to modify your diet to reduce your risk of developing these serious, life-threatening conditions. Inside, nutrition expert Karlyn Grimes shows you how to: Identify inflammatory foods Add inflammation-fighting foods to any diet Create an anti-inflammation plan you can live with Get the whole family on board This book includes flexible meal plans, 150 delicious recipes, and time-saving shopping and preparation tips. It's all you need to create balanced meals using fresh, unprocessed foods that nurture your body and soul.
Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
