Inflammation In Neuropsychiatric Disorders

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Inflammation in Psychiatry

A. Halaris,B.E. Leonard
Inflammation in Psychiatry Book PDF

Author : A. Halaris,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Page : 218 pages
File Size : 43,7 Mb
Release : 2013-02-27
Category : Medical
ISBN : 9783318023114

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Inflammation in Psychiatry by A. Halaris,B.E. Leonard Pdf

Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.

Inflammation in Neuropsychiatric Disorders

Anonim
Inflammation in Neuropsychiatric Disorders Book PDF

Author : Anonim
Publisher : Academic Press
Page : 200 pages
File Size : 43,9 Mb
Release : 2012-12-31
Category : Psychology
ISBN : 9780123983206

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Inflammation in Neuropsychiatric Disorders by Anonim Pdf

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. Covers reviews of methodology and research in all aspects of protein chemistry Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics

The Role of Inflammation in the Etiology and Treatment of Schizophrenia

Ole Köhler-Forsberg,Belinda Lennox,Norbert Müller
The Role of Inflammation in the Etiology and Treatment of Schizophrenia Book PDF

Author : Ole Köhler-Forsberg,Belinda Lennox,Norbert Müller
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 44,5 Mb
Release : 2020-12-23
Category : Medical
ISBN : 9782889662692

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The Role of Inflammation in the Etiology and Treatment of Schizophrenia by Ole Köhler-Forsberg,Belinda Lennox,Norbert Müller Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Mechanisms of Neuroinflammation

Gonzalo Emiliano Aranda Abreu
Mechanisms of Neuroinflammation Book PDF

Author : Gonzalo Emiliano Aranda Abreu
Publisher : BoD – Books on Demand
Page : 320 pages
File Size : 50,6 Mb
Release : 2017-08-23
Category : Medical
ISBN : 9789535134510

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Mechanisms of Neuroinflammation by Gonzalo Emiliano Aranda Abreu Pdf

"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.

Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Robert Dantzer,Lucile Capuron
Inflammation Associated Depression Evidence Mechanisms and Implications Book PDF

Author : Robert Dantzer,Lucile Capuron
Publisher : Springer
Page : 357 pages
File Size : 43,7 Mb
Release : 2016-12-28
Category : Medical
ISBN : 9783319511528

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Inflammation-Associated Depression: Evidence, Mechanisms and Implications by Robert Dantzer,Lucile Capuron Pdf

Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.

Inflammation and Oxidative Stress in Neurological Disorders

Akhlaq A. Farooqui
Inflammation and Oxidative Stress in Neurological Disorders Book PDF

Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
Page : 355 pages
File Size : 48,9 Mb
Release : 2014-01-27
Category : Medical
ISBN : 9783319041117

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Inflammation and Oxidative Stress in Neurological Disorders by Akhlaq A. Farooqui Pdf

Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.

Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders

Yong-Ku Kim
Neuroinflammation Gut Brain Axis and Immunity in Neuropsychiatric Disorders Book PDF

Author : Yong-Ku Kim
Publisher : Unknown
Page : 0 pages
File Size : 42,8 Mb
Release : 2023
Category : Electronic
ISBN : 9811973776

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Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders by Yong-Ku Kim Pdf

This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.

Psychotic Disorders

Carol A. Tamminga MD,Jim van Os MD, PhD, MRCPsych,Ulrich Reininghaus PhD, MSc, Dipl.-Psych.,Elena Ivleva MD, PhD
Psychotic Disorders Book PDF

Author : Carol A. Tamminga MD,Jim van Os MD, PhD, MRCPsych,Ulrich Reininghaus PhD, MSc, Dipl.-Psych.,Elena Ivleva MD, PhD
Publisher : Oxford University Press
Page : 400 pages
File Size : 47,9 Mb
Release : 2020-10-20
Category : Medical
ISBN : 9780190653293

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Psychotic Disorders by Carol A. Tamminga MD,Jim van Os MD, PhD, MRCPsych,Ulrich Reininghaus PhD, MSc, Dipl.-Psych.,Elena Ivleva MD, PhD Pdf

Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.

Comorbidity of Mental and Physical Disorders

N. Sartorius,R.I.G. Holt,M. Maj
Comorbidity of Mental and Physical Disorders Book PDF

Author : N. Sartorius,R.I.G. Holt,M. Maj
Publisher : Karger Medical and Scientific Publishers
Page : 200 pages
File Size : 40,5 Mb
Release : 2014-12-01
Category : Psychology
ISBN : 9783318026047

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Comorbidity of Mental and Physical Disorders by N. Sartorius,R.I.G. Holt,M. Maj Pdf

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Neuropsychiatric Disorders

Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda
Neuropsychiatric Disorders Book PDF

Author : Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda
Publisher : Springer Science & Business Media
Page : 351 pages
File Size : 47,7 Mb
Release : 2010-08-09
Category : Medical
ISBN : 9784431538714

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Neuropsychiatric Disorders by Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda Pdf

Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the latest findings in the field and includes chapters on delusional symptoms, mood disorders and neurotic symptoms, cognitive impairment, behavioral and personality changes, and recently, cerebral alterations revealed in PTSD patients and in endogenous psychoses through neuroimaging and neuropathology. These findings will certainly widen the realm of neuropsychiatry going forward and will prove of great value to specialists as well as to academics and trainees in neurology, psychiatry, neuropsychology, neuroradiology, neuropathology, neurophysiology, neurochemistry, and clinical genetics. Ultimately, neuropsychiatry aims to prevent and reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders.

Neuroinflammation and Schizophrenia

Golam M. Khandaker,Urs Meyer,Peter B. Jones
Neuroinflammation and Schizophrenia Book PDF

Author : Golam M. Khandaker,Urs Meyer,Peter B. Jones
Publisher : Springer
Page : 244 pages
File Size : 42,6 Mb
Release : 2020-01-23
Category : Medical
ISBN : 303039140X

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Neuroinflammation and Schizophrenia by Golam M. Khandaker,Urs Meyer,Peter B. Jones Pdf

This book provides a comprehensive summary of the cutting edge scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychotic disorders. It illustrates the role of inflammation and immunity in schizophrenia drawing on both basic science and clinical research. The chapters provide up-to-date summaries of immunological risk factors for schizophrenia and related psychotic disorders, and underlying mechanisms as informed by neuroimaging, genetic, clinical and animal experimental studies. In addition, the book will illuminate the scope for immunological treatment for schizophrenia.

Inflammatory Disorders of the Nervous System

Alireza Minagar,J. Steven Alexander
Inflammatory Disorders of the Nervous System Book PDF

Author : Alireza Minagar,J. Steven Alexander
Publisher : Humana Press
Page : 281 pages
File Size : 44,8 Mb
Release : 2017-03-20
Category : Medical
ISBN : 9783319512204

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Inflammatory Disorders of the Nervous System by Alireza Minagar,J. Steven Alexander Pdf

This thoroughly updated edition covers all clinical aspects of neuroinflammation. The latest developments in pathogenesis and advances in treatment are provided, along with an understanding of the immune system's role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade. Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice.

Immunological Alterations in Psychiatric Diseases

A. Henneberg,Wolfgang P. Kaschka
Immunological Alterations in Psychiatric Diseases Book PDF

Author : A. Henneberg,Wolfgang P. Kaschka
Publisher : Karger Medical and Scientific Publishers
Page : 132 pages
File Size : 47,5 Mb
Release : 1997
Category : Medical
ISBN : 3805563841

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Immunological Alterations in Psychiatric Diseases by A. Henneberg,Wolfgang P. Kaschka Pdf

In addition, fundamental questions concerning the bi-directional interactions between the central nervous system and the immune system are discussed and the role of viruses and infectious processes closely examined. As such, this book offers a unique presentation of the state of the art in psychoimmunology and, at the same time, shows many important challenges for future research into the field of intersystemic interactions and their impact on the etiology and pathogenesis of psychiatric diseases.

Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders

Yong-Ku Kim
Neuroinflammation Gut Brain Axis and Immunity in Neuropsychiatric Disorders Book PDF

Author : Yong-Ku Kim
Publisher : Springer Nature
Page : 564 pages
File Size : 54,5 Mb
Release : 2023-03-22
Category : Medical
ISBN : 9789811973765

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Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders by Yong-Ku Kim Pdf

This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.

Biomarkers of Neuroinflammation

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Biomarkers of Neuroinflammation Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 89 pages
File Size : 53,8 Mb
Release : 2018-03-16
Category : Medical
ISBN : 9780309463652

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Biomarkers of Neuroinflammation by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) disorders. However, there is little agreement on the pathophysiological mechanisms that underlie the manifestations of neuroinflammation in the CNS compartment and how neuroinflammation operates as a driver and also as a consequence of disease in the brain. Moreover, another unclear area is how to translate increased understanding of the mechanisms that underlie neuroinflammation and its manifestations in the CNS to therapeutics. To address these gaps in understanding mechanisms and how to translate that understanding into therapeutics, the Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop on March 20-21, 2017, bringing together key leaders in the field from industry, academia, and governmental agencies to explore the role and mechanisms of neuroinflammation in a variety of CNS diseases. The workshop also considered strategies to advance the identification and validation of biomarkers of neuroinflammation that could accelerate development of therapies, bringing much-needed treatments to patients with disorders ranging from neuroinflammatory diseases such as multiple sclerosis (MS) to neuropsychiatric disorders such as depression. This publication summarizes the presentations and discussions from the workshop.