Inflammatory Mechanisms In Allergic Diseases

Author : Burton Zweiman,Lawrence B. Schwartz
Publisher : CRC Press
Page : 604 pages
File Size : 49,9 Mb
Release : 2023-01-06
Category : Medical
ISBN : 9781000893762

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Inflammatory Mechanisms in Allergic Diseases by Burton Zweiman,Lawrence B. Schwartz Pdf

Contains patterns of allergic reactivity for disorders such as asthma, atopic dermatitis, urticaria, and anaphylaxis. Written by leading experts in the field, Inflammatory Mechanisms in Allergic Diseases covers non-anaphylactic drug disorders; synthesis and formation of IgE antibodies; new treatments using allergenic peptides, immunostimulatory oligonucleotides, and pharmacogenomics;recent advances targeting effector mechanisms; hypersensitivity reactions to drugs and more! With over 3100 references, tables, drawings, and micrographs, Inflammatory Mechanisms in Allergic Diseases is an essential reference for allergists, pulmonologists, immunologists, dermatologists, ophthalmologists, otolaryngologists, internists, pediatricians, family practitioners, and medical students in these disciplines.

Author : Judah A. Denburg
Publisher : Springer Science & Business Media
Page : 589 pages
File Size : 40,6 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781475727760

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Allergy and Allergic Diseases by Judah A. Denburg Pdf

Allergy and Allergic Diseases has been organized to provide an up-to-date, clinically relevant compilation of one of the most exciting areas of investigation in medicine today-allergic disease, especially as it pertains to the skin, airways, and bowel. With the dramatic rise in the incidence of various allergic disorders worldwide, and the coming of age of the discipline of Clinical Immunology and Allergy, the interface between basic and clinical science in this arena demands highlighting in this comprehensive new syn thesis.1t is with the hope of filling this evident need that Allergy and Allergic Diseases: The New Mechanisms and Therapeutics has been put together. The book's content is divided into both basic and clinical sections, with emphasis on various components of the immune and inflammatory response as they relate to the development of allergic disease. Topics span the range from molecular biology to clinical symptomatology, with an effort to make this of interest to as broad a constituency as possible. This book will therefore be of substantial interest to specialists in Clinical Immunology and Allergy, scientists studying the cellular and molecular biology of in flammation and immunity, as well as internists, teachers, developers of medical school curricula, and members of industry focused on drug discovery and therapeutics. Indeed, a separate section has been added to deal with some specific issues in this latter field.

Author : Douglas S. Robinson
Publisher : Karger Medical and Scientific Publishers
Page : 227 pages
File Size : 43,6 Mb
Release : 2000-01-01
Category : Medical
ISBN : 9783805571128

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Immunological Mechanisms in Asthma and Allergic Diseases by Douglas S. Robinson Pdf

This book explores the cellular and molecular mechanisms involved in asthma and allergic diseases, from basic immunology to the treatment of patients. Arising from a special symposium held to celebrate Professor A. Barry Kay's 20th anniversary as Head of the Department of Allergy and Clinical Immunology at the National Heart and Lung Institute, London, the publication presents 18 review articles by an impressive cross section of experts in the field. Topics considered include Th1 and Th2 cells, the regultion of Th2 cytokine transcription, the role of T cells in the immunopathogenesis of asthma, and MHC-restricted IgE-independent T-cell-induced late-phase responses in human subjects. Further chapters focus on eosinophil adhesion and activation, the role of C-C chemokines in the recruitment of eosinophils, and the interactions between eosinophils and fibroblasts. T-cell recruitment and T-cell interactions in cutaneous basophil hypersensitivity and fibrotic lung disease are discussed, as is the molecular pathology of allergic disease. Finally, treatment approaches are considered in chapters on the molecular basis of corticosteroid actions in asthma, immunosuppression in asthma, and immunotherapy of allergic diseases.

Author : Thomas A.E. Platts-Mills
Publisher : CRC Press
Page : 260 pages
File Size : 44,9 Mb
Release : 1999-04-27
Category : Medical
ISBN : 1566703735

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Asthma by Thomas A.E. Platts-Mills Pdf

Asthma is a disease which, beginning in the 1980s, increased in the United States and other countries in both its prevalence and mortality. According to reports by the Center for Disease Control, the number of people with asthma increased by 42% in the last decade, with children, ethnic minorities and the urban poor being most at risk. Timely research on the causes and mechanisms behind the dramatic increase of asthma in the United States and other nations-to epidemic proportions-is presented in this volume. Investigators heading up eight research groups in asthma and/or allergy present their most recent findings, funded by the Center for Indoor Air Research. In addition to the work underway and discussions/suggestions on present research problems, ASTHMA: Causes and Mechanisms of an Epidemic Inflammatory Disease provides a chapter on the causes of asthma-and the reasons for its recent spread, so hotly discussed in the current literature. Researchers in the fields of asthma and allergy, health care providers, and others who follow research in either of these two developing areas will benefit from this book. The book is written at the level of one investigator to another.

Author : K. Izuhara,Stephen T. Holgate,Marsha Wills-Karp
Publisher : John Wiley & Sons
Page : 738 pages
File Size : 40,5 Mb
Release : 2011-07-20
Category : Medical
ISBN : 9781444346671

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Inflammation and Allergy Drug Design by K. Izuhara,Stephen T. Holgate,Marsha Wills-Karp Pdf

Our knowledge and understanding of allergic diseases of the respiratory tract has improved to a point where new therapies are being developed for patient benefit. Inflammation and Allergy Drug Design explains the biologic science that underpins the pathophysiology of asthma and related disorders, as well as their mechanisms. This authoritative guide consists of 25 chapters, each detailing the cutting-edge developments in a particular field. It is divided into three parts, covering cytokines, chemokines, grow factors and mediators. This book allows immunologists, allergologists and researchers in the pharmaceutical industry to learn and appreciate the target biology in drug development. It also provides medical and pharmaceutical postgraduate students and clinicians with a basic understanding of allergic diseases in the respiratory tract.

Author : Phil Lieberman,John A. Anderson
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 47,8 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781475725919

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Allergic Diseases by Phil Lieberman,John A. Anderson Pdf

A concise, easy-to-read, comprehensive, and up-to-date guide designed to help primary care physicians, pediatricians, and internists with the day-to-day diagnosis and treatment of their allergic patients. Its distinguished contributors-all highly experienced clinicians-integrate our latest understanding of the basic mechanisms of allergic disease and develop state-of-the-art treatment protocols that allow busy physicians to sharpen their allergy management strategies significantly. "Summary Boxes" utilized throughout book summarize crucial points and processes for time-pressured physicians, allowing them to quickly grasp a therapeutic situation and determine the best and most up-to-date treatment options. Each chapter contains numerous figures and tables to enhance understanding, treatment algorithms, and a list of suggested readings carefully chosen to deepen knowledge and insight into key points.

Author : National Research Council,Institute of Medicine,Committee on the Health Effects of Indoor Allergens
Publisher : National Academies Press
Page : 321 pages
File Size : 40,5 Mb
Release : 1993-02-01
Category : Science
ISBN : 9780309048316

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Indoor Allergens by National Research Council,Institute of Medicine,Committee on the Health Effects of Indoor Allergens Pdf

More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and schoolâ€"where we spend as much as 98 percent of our time. Developed by medical, public health, and engineering professionals working together, this unique volume summarizes what is known about indoor allergens, how they affect human health, the magnitude of their effect on various populations, and how they can be controlled. The book addresses controversies, recommends research directions, and suggests how to assist and educate allergy patients, as well as professionals. Indoor Allergens presents a wealth of information about common indoor allergens and their varying effects, from significant hay fever to life-threatening asthma. The volume discusses sources of allergens, from fungi and dust mites to allergenic chemicals, plants, and animals, and examines practical measures for their control. Indoor Allergens discusses how the human airway and immune system respond to inhaled allergens and assesses patient testing methods, covering the importance of the patient's medical history and outlining procedures and approaches to interpretation for skin tests, in vitro diagnostic tests, and tests of patients' pulmonary function. This comprehensive and practical volume will be important to allergists and other health care providers; public health professionals; specialists in building design, construction, and maintenance; faculty and students in public health; and interested allergy patients.

Author : Donald Y. M. Leung,Hugh Sampson,Raif Geha,Stanley J. Szefler
Publisher : Elsevier Health Sciences
Page : 705 pages
File Size : 47,6 Mb
Release : 2010-10-13
Category : Medical
ISBN : 9781437737783

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Pediatric Allergy: Principles and Practice E-Book by Donald Y. M. Leung,Hugh Sampson,Raif Geha,Stanley J. Szefler Pdf

Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.

Author : Bao-Hui Cheng,Xiaojun Xiao,Jing Li,Yu Jin
Publisher : Frontiers Media SA
Page : 147 pages
File Size : 46,7 Mb
Release : 2023-04-24
Category : Medical
ISBN : 9782832521434

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Mechanisms and advances in respiratory allergic diseases by Bao-Hui Cheng,Xiaojun Xiao,Jing Li,Yu Jin Pdf

Author : Hans-Uwe Simon
Publisher : CRC Press
Page : 404 pages
File Size : 55,6 Mb
Release : 2000-04-26
Category : Medical
ISBN : 0849396840

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CRC Desk Reference for Allergy and Asthma by Hans-Uwe Simon Pdf

As the prevalence of allergic diseases and asthma has increased in recent years, scientists have intensified research efforts to understand the pathogenesis of these sometimes debilitating conditions. Indeed, researchers have provided key insights-and new concepts-that have changed therapeutic strategies. Moreover, allergic inflammation has served as something of a model in furthering our understanding of regulatory mechanisms of inflammation in general. Presented in an encyclopedic format, the CRC Desk Reference for Allergy and Asthma provides the latest scientific information on allergic diseases and asthma. It combines knowledge from clinical immunology with basic immunology, pharmacology, biochemistry, and molecular biology to examine new treatment strategies for allergic diseases and asthma. Highlights of the CRC Desk Reference for Allergy and Asthma include: EASE OF USE. This desk reference presents topics in alphabetical order so that they are easy to find. CROSS-REFERENCING. Utilizes cross-referencing to aid in the rapid switch between basic and clinical science. UNIFIED NOMENCLATURE. Greatly assists those readers who are new in the field. HIGHLIGHTS VITAL INFORMATION. Vital information is highlighted in boxes, allowing rapid identification of key concepts. Written by leading authorities in the field, the CRC Desk Reference for Allergy and Asthma serves as a timely reference for anyone interested in this area of research. Not only does it present information in an easy-to-use format, but it addresses many hot topics and views that will have sustaining value for years to come.

Author : Stephen T Holgate,Martin K. Church,David H. Broide,Fernando D Martinez
Publisher : Elsevier Health Sciences
Page : 411 pages
File Size : 52,5 Mb
Release : 2011-10-11
Category : Medical
ISBN : 9780702050411

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Allergy E-Book by Stephen T Holgate,Martin K. Church,David H. Broide,Fernando D Martinez Pdf

The new edition of Allergy, by Drs. Stephen Holgate, Martin Church, David Broide, and Fernando Martinez, uses an enhanced clinical focus to provide the clear, accessible guidance you need to treat allergy patients. A more consistent format throughout features new differential diagnosis and treatment algorithms, updated therapeutic drug information in each chapter, and additional coverage of pediatric allergies. With current discussions of asthma, allergens, pollutants, drug treatment, and more, this comprehensive resource is ideal for any non-specialist who treats patients with allergies. Prescribe appropriate therapies and effectively manage patients’ allergies using detailed treatment protocols. Identify allergic conditions quickly and easily with algorithms that provide at-a-glance assistance. Explore topics in greater detail using extensive references to key literature. Manage allergies in both adult and pediatric patients using coverage of treatment practices for both in each chapter. Stay current on hot topics including asthma, allergens, pollutants, and more. Get up-to-date coverage of cell-based condition with brand new chapters on Eosinophilia: Clinical Manifestations and Therapeutic Options and Systemic Mastocytosis. Apply the latest best practices through new and updated treatment algorithms. Find therapeutic drug information more easily with guidance incorporated into each chapter.

Author : Ruby Pawankar,Stephen T. Holgate,Lanny J. Rosenwasser
Publisher : Springer Science & Business Media
Page : 608 pages
File Size : 46,7 Mb
Release : 2009-03-13
Category : Medical
ISBN : 9784431883159

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Allergy Frontiers:Classification and Pathomechanisms by Ruby Pawankar,Stephen T. Holgate,Lanny J. Rosenwasser Pdf

When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as “Exosomes, naturally occurring minimal antigen presenting units” and “Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene.” The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic u- ally confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease.

Author : John Bienenstock
Publisher : Karger Medical and Scientific Publishers
Page : 286 pages
File Size : 41,9 Mb
Release : 2012
Category : Medical
ISBN : 9783805599849

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Allergy and the Nervous System by John Bienenstock Pdf

In recent decades, it has become increasingly clear that the immune and nervous systems communicate with each other in a bidirectional way. The role of chronic stress in allergic disease and inflammation has been confirmed and raises the important question of how psychosocial factors influence the outcome of allergic conditions. This book explains the roles of the autonomic, peripheral and central nervous systems in allergy and asthma. With contributions from leading authorities - both clinicians and basic researchers - it covers a wide range of topics from psychology over epigenetics to brain imaging. The 15 invited reviews discuss topics such as the role of stress in allergy and asthma, the concept of programming in utero and in childhood and adulthood, the significance of neurotrophins, and the involvement of the nervous system in the lung in asthma and lung inflammation. The interactions between mast cells and the nervous system are examined as well as the role of the gut microbiome in regulating the hypothalamic-pituitary-adrenal axis and the stress response. Further chapters are devoted to neural and behavioral changes associated with food allergy, the role of the neuroendocrine system in the skin, and the way in which itch is processed by the brain. Unique in its field, this valuable volume is recommended reading not only for allergologists, psychologists specializing in allergy and somatic manifestations, respirologists and asthma researchers, but for anyone interested in psychoneuroimmunology.

Author : Gerald J. Gleich
Publisher : CRC Press
Page : 536 pages
File Size : 41,5 Mb
Release : 2019-08-16
Category : Medical
ISBN : 9781000723571

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Eosinophils in Allergy and Inflammation by Gerald J. Gleich Pdf

This work presents the proceedings of a conference held at Adare Manor, County Limerick, Ireland. It provides an updated, in-depth review of the biological role of eosinophils in allergic diseases, summarizing basic knowledge of these unique cationic proteins. The book features an annotated discussion of the conference's post-presentation question-and-answer session.

Author : Kurt Blaser
Publisher : Karger Medical and Scientific Publishers
Page : 243 pages
File Size : 47,7 Mb
Release : 2008-01-01
Category : Medical
ISBN : 9783805586283

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T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases by Kurt Blaser Pdf

This book presents the state of the art in cellular and molecular mechanisms regulating the immune response in allergic inflammation. Special attention is given to the central role of regulatory T cells (Treg) in immune regulation and induction of peripheral tolerance, as well as to the relevance of Th17 cells in chronic inflammation. The importance of Treg and Th17 cells is demonstrated in bronchial asthma, atopic eczema, contact dermatitis and delayed-type hypersensitivity. Furthermore, T-cell-mediated regulatory mechanisms in helminthic infections and fungal allergy are discussed. Several chapters are devoted to the therapeutic consequences that these recently discovered T-cell functions may have. Their role as a potential target for specific immunotherapy is evaluated and novel approaches for peripheral tolerance induction and treatment of allergic and asthmatic diseases and inflammation are suggested. Stem cell transplantation as a future therapeutic intervention in regulatory T-cell disorders is also considered. Well edited and up to date, this volume is recommended reading for allergologists, immunologists, dermatologists and any scientist interested in the immunological events regulating allergic inflammation in general and allergic manifestations in different organs.