Inorganic Chemistry In Biology

Author : Robert R. Crichton
Publisher : Elsevier
Page : 381 pages
File Size : 42,8 Mb
Release : 2007-12-11
Category : Science
ISBN : 0080556221

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Biological Inorganic Chemistry by Robert R. Crichton Pdf

The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Author : Ivano Bertini
Publisher : University Science Books
Page : 794 pages
File Size : 47,7 Mb
Release : 2007
Category : Science
ISBN : 1891389432

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Biological Inorganic Chemistry by Ivano Bertini Pdf

Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Author : Gilles Gasser
Publisher : John Wiley & Sons
Page : 437 pages
File Size : 42,5 Mb
Release : 2014-04-14
Category : Science
ISBN : 9781118684153

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Inorganic Chemical Biology by Gilles Gasser Pdf

Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques and Applications provides a comprehensive overview of the current and emerging role of metal complexes in chemical biology. Throughout all of the chapters there is a strong emphasis on fundamental theoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooks for the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals in chemical biology • Cell and organism imaging and probing DNA using metal and metal carbonyl complexes • Detection of metal ions, anions and small molecules using metal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts in living cells Written by a team of international experts, Inorganic Chemical Biology: Principles, Techniques and Applications is a must-have for bioinorganic, bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

Author : Robert R. Crichton,Ricardo O. Louro
Publisher : Newnes
Page : 329 pages
File Size : 50,9 Mb
Release : 2012-12-31
Category : Science
ISBN : 9780444563590

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Practical Approaches to Biological Inorganic Chemistry by Robert R. Crichton,Ricardo O. Louro Pdf

The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures

Author : J. J. R. Frausto da Silva,Robert Joseph Paton Williams
Publisher : Oxford University Press
Page : 608 pages
File Size : 49,7 Mb
Release : 2001-08-16
Category : Medical
ISBN : 0198508484

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The Biological Chemistry of the Elements by J. J. R. Frausto da Silva,Robert Joseph Paton Williams Pdf

This text describes the functional role of the twenty inorganic elements essential to life in living organisms.

Author : Patricia C. Wilkins,Ralph G. Wilkins
Publisher : Oxford University Press, USA
Page : 102 pages
File Size : 46,7 Mb
Release : 1997
Category : Science
ISBN : UOM:39015048553377

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Inorganic Chemistry in Biology by Patricia C. Wilkins,Ralph G. Wilkins Pdf

Approximately a quarter of this book is devoted to the way metal ions interact with biomolecules and the remainder discusses the biologically important elements and their occurrence and function in biomaterials.

Author : Robert R. Crichton
Publisher : Academic Press
Page : 692 pages
File Size : 49,9 Mb
Release : 2018-05-23
Category : Science
ISBN : 9780128117422

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Biological Inorganic Chemistry by Robert R. Crichton Pdf

Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students. Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Authors Association Features new sections: an overview of the different functions of essential metal ions; toxic metals in diagnosis and therapeutics; crystal and ligand field theory and their limitations; molecular orbital theory; genetic and molecular biological approaches to study metals; more complex cofactors and their biosynthesis; photosynthetic oxidation of water; man-made environmental pollution; and metals as poisons

Author : J. A. Cowan
Publisher : John Wiley & Sons
Page : 458 pages
File Size : 41,5 Mb
Release : 1997-03-21
Category : Science
ISBN : 0471188956

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Inorganic Biochemistry by J. A. Cowan Pdf

Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert; dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung.

Author : P.C. et al WILKINS
Publisher : Unknown
Page : 128 pages
File Size : 54,8 Mb
Release : 1997
Category : Electronic
ISBN : OCLC:895874517

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Inorganic Chemistry in Biology by P.C. et al WILKINS Pdf

Author : Wolfgang Kaim,Brigitte Schwederski,Axel Klein
Publisher : John Wiley & Sons
Page : 510 pages
File Size : 45,5 Mb
Release : 2013-08-01
Category : Science
ISBN : 9781118659267

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Bioinorganic Chemistry -- Inorganic Elements in the Chemistry of Life by Wolfgang Kaim,Brigitte Schwederski,Axel Klein Pdf

The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life sciences due to its highly interdisciplinary nature. Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. The second edition of this classic text has been fully revised and updated to include new structure information, emerging developments in the field, and an increased focus on medical applications of inorganic compounds. New topics have been added including materials aspects of bioinorganic chemistry, elemental cycles, bioorganometallic chemistry, medical imaging and therapeutic advances. Topics covered include: Metals at the center of photosynthesis Uptake, transport, and storage of essential elements Catalysis through hemoproteins Biological functions of molybdenum, tungsten, vanadium and chromium Function and transport of alkaline and alkaline earth metal cations Biomineralization Biological functions of the non-metallic inorganic elements Bioinorganic chemistry of toxic metals Biochemical behavior of radionuclides and medical imaging using inorganic compounds Chemotherapy involving non-essential elements This full color text provides a concise and comprehensive review of bioinorganic chemistry for advanced students of chemistry, biochemistry, biology, medicine and environmental science.

Author : Rosette M. Roat-Malone
Publisher : John Wiley & Sons
Page : 350 pages
File Size : 48,7 Mb
Release : 2020-03-17
Category : Science
ISBN : 9781119535218

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Bioinorganic Chemistry by Rosette M. Roat-Malone Pdf

Introduces students to the basics of bioinorganic chemistry This book provides the fundamentals for inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. It provides essential background material, followed by detailed information on selected topics, to give readers the background, tools, and skills they need to research and study bioinorganic topics of interest to them. To reflect current practices and needs, instrumental methods and techniques are referred to and mixed in throughout the book. Bioinorganic Chemistry: A Short Course, Third Edition begins with a chapter on Inorganic Chemistry and Biochemistry Essentials. It then continues with chapters on: Computer Hardware, Software, and Computational Chemistry Methods; Important Metal Centers in Proteins; Myoglobins, Hemoglobins, Superoxide Dismutases, Nitrogenases, Hydrogenases, Carbonic Anhydrases, and Nitrogen Cycle Enzymes. The book concludes with chapters on Nanobioinorganic Chemistry and Metals in Medicine. Readers are also offered end-of-section summaries, conclusions, and thought problems. Reduces size of the text from previous edition to match the first, keeping it appropriate for a one-semester course Offers primers and background materials to help students feel comfortable with research-level bioinorganic chemistry Emphasizes select and diverse topics using extensive references from current scientific literature, with more emphasis on molecular biology in the biochemistry section, leading to a discussion of CRISPR technology Adds new chapters on hydrogenases, carbonic anhydrases, and nitrogen cycle enzymes, along with a separate chapter on nanobioinorganic chemistry Features expanded coverage of computer hardware and software, metalloenzymes, and metals in medicines Supplemented with a companion website for students and instructors featuring Powerpoint and JPEG figures and tables, arranged by chapter Appropriate for one-semester bioinorganic chemistry courses, Bioinorganic Chemistry: A Short Course, Third Edition is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers in need of a general introduction to the subject, as well as chemists requiring an accessible reference.

Author : Stephen J. Lippard,Jeremy Mark Berg
Publisher : University Science Books
Page : 444 pages
File Size : 54,7 Mb
Release : 1994
Category : Medical
ISBN : 0935702725

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Principles of Bioinorganic Chemistry by Stephen J. Lippard,Jeremy Mark Berg Pdf

The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance.

Author : Ajay Kumar Goswami,Irena Kostova
Publisher : Walter de Gruyter GmbH & Co KG
Page : 164 pages
File Size : 51,6 Mb
Release : 2022-01-19
Category : Science
ISBN : 9781501516153

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Medicinal and Biological Inorganic Chemistry by Ajay Kumar Goswami,Irena Kostova Pdf

The book provides a detailed state-of-the-art overview of inorganic chemistry applied to medicinal chemistry and biology. It covers the newly emerging field of metals in medicine and the future of medicinal inorganic chemistry. Further it includes metal based medicines used in alternative systems of Ayurveda as well as Tibetan Zuotai to make it a holistic approach. It is an essential reading for every researcher and student in medicinal and bioinorganic chemistry.

Author : Nicholas P Farrell
Publisher : Royal Society of Chemistry
Page : 174 pages
File Size : 52,7 Mb
Release : 2007-10-31
Category : Medical
ISBN : 9781847552242

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Uses of Inorganic Chemistry in Medicine by Nicholas P Farrell Pdf

Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline.

Author : M. N. Hughes
Publisher : Unknown
Page : 356 pages
File Size : 43,8 Mb
Release : 1981-05-06
Category : Science
ISBN : MINN:31951P001143842

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The Inorganic Chemistry of Biological Processes by M. N. Hughes Pdf

A survey of the occurrence and role of metal ions in biological processes and how they may be studied experimentally. Provides a summary of relevant biology, and properties of transition metal complexes and the mechanisms of their reactions in solution. Discusses the role of platinum complexes in cancer chemotherapy. Features extensive rewriting in light of recent advances, and new material on transport and storage of iron, and on non-metals.