Inorganic Chemical Biology

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Biological Inorganic Chemistry

Author : Robert R. Crichton
Publisher : Elsevier
Page : 381 pages
File Size : 42,5 Mb
Release : 2007-12-11
Category : Science
ISBN : 0080556221

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Biological Inorganic Chemistry by Robert R. Crichton Pdf

The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Inorganic Chemical Biology

Author : Gilles Gasser
Publisher : John Wiley & Sons
Page : 437 pages
File Size : 46,8 Mb
Release : 2014-04-14
Category : Science
ISBN : 9781118684153

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Inorganic Chemical Biology by Gilles Gasser Pdf

Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques and Applications provides a comprehensive overview of the current and emerging role of metal complexes in chemical biology. Throughout all of the chapters there is a strong emphasis on fundamental theoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooks for the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals in chemical biology • Cell and organism imaging and probing DNA using metal and metal carbonyl complexes • Detection of metal ions, anions and small molecules using metal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts in living cells Written by a team of international experts, Inorganic Chemical Biology: Principles, Techniques and Applications is a must-have for bioinorganic, bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

Biological Inorganic Chemistry

Author : Ivano Bertini
Publisher : University Science Books
Page : 794 pages
File Size : 52,8 Mb
Release : 2007
Category : Science
ISBN : 1891389432

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Biological Inorganic Chemistry by Ivano Bertini Pdf

Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Inorganic Chemical Biology

Author : Gilles Gasser
Publisher : John Wiley & Sons
Page : 437 pages
File Size : 52,5 Mb
Release : 2014-06-23
Category : Science
ISBN : 9781118510025

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Inorganic Chemical Biology by Gilles Gasser Pdf

Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques and Applications provides a comprehensive overview of the current and emerging role of metal complexes in chemical biology. Throughout all of the chapters there is a strong emphasis on fundamental theoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooks for the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals in chemical biology • Cell and organism imaging and probing DNA using metal and metal carbonyl complexes • Detection of metal ions, anions and small molecules using metal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts in living cells Written by a team of international experts, Inorganic Chemical Biology: Principles, Techniques and Applications is a must-have for bioinorganic, bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

Practical Approaches to Biological Inorganic Chemistry

Author : Robert R. Crichton,Ricardo O. Louro
Publisher : Newnes
Page : 329 pages
File Size : 44,7 Mb
Release : 2012-12-31
Category : Science
ISBN : 9780444563590

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Practical Approaches to Biological Inorganic Chemistry by Robert R. Crichton,Ricardo O. Louro Pdf

The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures

Medicinal Inorganic Chemistry

Author : Jonathan L. Sessler
Publisher : Unknown
Page : 480 pages
File Size : 52,9 Mb
Release : 2005
Category : Medical
ISBN : UOM:39015062459931

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Medicinal Inorganic Chemistry by Jonathan L. Sessler Pdf

This book reviews the current diagnostic and therapeutic uses of metal-containing compounds in medicine, as well as the role of metals in disease.

The Biological Chemistry of the Elements

Author : J. J. R. Frausto da Silva,Robert Joseph Paton Williams
Publisher : Oxford University Press
Page : 608 pages
File Size : 48,7 Mb
Release : 2001-08-16
Category : Medical
ISBN : 0198508484

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The Biological Chemistry of the Elements by J. J. R. Frausto da Silva,Robert Joseph Paton Williams Pdf

This text describes the functional role of the twenty inorganic elements essential to life in living organisms.

Biological Inorganic Chemistry

Author : Robert R. Crichton
Publisher : Academic Press
Page : 692 pages
File Size : 43,6 Mb
Release : 2018-05-23
Category : Science
ISBN : 9780128117422

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Biological Inorganic Chemistry by Robert R. Crichton Pdf

Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students. Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Authors Association Features new sections: an overview of the different functions of essential metal ions; toxic metals in diagnosis and therapeutics; crystal and ligand field theory and their limitations; molecular orbital theory; genetic and molecular biological approaches to study metals; more complex cofactors and their biosynthesis; photosynthetic oxidation of water; man-made environmental pollution; and metals as poisons

Inorganic Biochemistry

Author : J. A. Cowan
Publisher : John Wiley & Sons
Page : 458 pages
File Size : 48,9 Mb
Release : 1997-03-21
Category : Science
ISBN : 0471188956

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Inorganic Biochemistry by J. A. Cowan Pdf

Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert; dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung.

The Chemical Biology of Phosphorus

Author : Christopher T Walsh
Publisher : Royal Society of Chemistry
Page : 567 pages
File Size : 54,5 Mb
Release : 2020-10-29
Category : Science
ISBN : 9781839162329

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The Chemical Biology of Phosphorus by Christopher T Walsh Pdf

Alexander Todd, the 1957 Nobel laureate in chemistry is credited with the statement: “where there is life, there is phosphorus”. Phosphorus chemical biology underlies most of life’s reactions and processes, from the covalent bonds that hold RNA and DNA together, to the making and spending 75 kg of ATP every day, required to run almost all metabolic and mechanical events in cells. Authored by a renowned biochemist, The Chemical Biology of Phosphorus provides an in-depth, unifying chemical approach to the logic and reactivity of inorganic phosphate and its three major derivatives (anhydrides, mono- and diesters) throughout biology to examine why life depends on phosphorus. Covering the breadth of phosphorus chemistry in biology, this book is ideal for biochemistry students, postgraduates and researchers interested in the chemical logic of phosphate metabolites, energy generation, biopolymer accumulation and phosphoproteomics.

The Biological Chemistry of the Elements

Author : J. J. R. Fraústo da Silva,J. R. R. Fraústo da Silva,Robert Joseph Paton Williams
Publisher : Oxford University Press, USA
Page : 594 pages
File Size : 48,6 Mb
Release : 1991
Category : Science
ISBN : UCSD:31822007450620

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The Biological Chemistry of the Elements by J. J. R. Fraústo da Silva,J. R. R. Fraústo da Silva,Robert Joseph Paton Williams Pdf

The authors of this study on bio-inorganic chemistry seek to examine the importance of inorganic elements. They survey chemical and physical factors controlling the elements of life, discuss the functions of inorganic elements and examine the co-operative interaction in living systems.

Inorganic Chemistry in Biology

Author : Patricia C. Wilkins,Ralph G. Wilkins
Publisher : Oxford University Press, USA
Page : 102 pages
File Size : 55,9 Mb
Release : 1997
Category : Science
ISBN : UOM:39015048553377

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Inorganic Chemistry in Biology by Patricia C. Wilkins,Ralph G. Wilkins Pdf

Approximately a quarter of this book is devoted to the way metal ions interact with biomolecules and the remainder discusses the biologically important elements and their occurrence and function in biomaterials.

Bioinorganic Chemistry -- Inorganic Elements in the Chemistry of Life

Author : Wolfgang Kaim,Brigitte Schwederski,Axel Klein
Publisher : John Wiley & Sons
Page : 510 pages
File Size : 49,8 Mb
Release : 2013-08-01
Category : Science
ISBN : 9781118659267

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Bioinorganic Chemistry -- Inorganic Elements in the Chemistry of Life by Wolfgang Kaim,Brigitte Schwederski,Axel Klein Pdf

The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life sciences due to its highly interdisciplinary nature. Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. The second edition of this classic text has been fully revised and updated to include new structure information, emerging developments in the field, and an increased focus on medical applications of inorganic compounds. New topics have been added including materials aspects of bioinorganic chemistry, elemental cycles, bioorganometallic chemistry, medical imaging and therapeutic advances. Topics covered include: Metals at the center of photosynthesis Uptake, transport, and storage of essential elements Catalysis through hemoproteins Biological functions of molybdenum, tungsten, vanadium and chromium Function and transport of alkaline and alkaline earth metal cations Biomineralization Biological functions of the non-metallic inorganic elements Bioinorganic chemistry of toxic metals Biochemical behavior of radionuclides and medical imaging using inorganic compounds Chemotherapy involving non-essential elements This full color text provides a concise and comprehensive review of bioinorganic chemistry for advanced students of chemistry, biochemistry, biology, medicine and environmental science.

Medicinal and Biological Inorganic Chemistry

Author : Ajay Kumar Goswami,Irena Kostova
Publisher : Walter de Gruyter GmbH & Co KG
Page : 148 pages
File Size : 48,7 Mb
Release : 2022-01-19
Category : Science
ISBN : 9781501516115

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Medicinal and Biological Inorganic Chemistry by Ajay Kumar Goswami,Irena Kostova Pdf

The book provides a detailed state-of-the-art overview of inorganic chemistry applied to medicinal chemistry and biology. It covers the newly emerging field of metals in medicine and the future of medicinal inorganic chemistry. It is an essential reading for every researcher and student in medicinal and bioinorganic chemistry.

The Inorganic Chemistry of Biological Processes

Author : M. N. Hughes
Publisher : Unknown
Page : 356 pages
File Size : 52,5 Mb
Release : 1981-05-06
Category : Science
ISBN : MINN:31951P001143842

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The Inorganic Chemistry of Biological Processes by M. N. Hughes Pdf

A survey of the occurrence and role of metal ions in biological processes and how they may be studied experimentally. Provides a summary of relevant biology, and properties of transition metal complexes and the mechanisms of their reactions in solution. Discusses the role of platinum complexes in cancer chemotherapy. Features extensive rewriting in light of recent advances, and new material on transport and storage of iron, and on non-metals.