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Inspire Science: Chemistry, G9-12 Student Edition by McGraw Hill Pdf
Inspire Chemistry (c) 2020 provides an in-depth, collaborative, and projectbased learning experiencing focused on the science of chemistry. The program covers structure and properties of matter, chemical bonding and reactions, matter, energy, and equilibrium, and organic and nuclear chemistry, as well as cross-curricular earth science topics. Through inquiry-based and hands-on investigations of realworld phenomenon, students will construct explanations for scientific phenomenon and design solutions for real-world problems.
Advances in Heterocyclic Chemistry is the definitive series in the field—one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists, and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds
Author : Barry M. Trost,Chao-Jun Li Publisher : John Wiley & Sons Page : 420 pages File Size : 50,6 Mb Release : 2014-10-08 Category : Science ISBN : 9783527677917
Modern Alkyne Chemistry by Barry M. Trost,Chao-Jun Li Pdf
A comprehensive and up-to-date overview of alkyne chemistry, taking into account the progress made over the last two decades. The experienced editors are renowned world leaders in the field, while the list of contributors reads like a "Who's Who" of synthetic organic chemistry. The result is a valuable reference not only for organic chemists at universities and in the chemical industry, but also for biologists and material scientists involved in the modern synthesis of organic compounds and materials.
Flow and Microreactor Technology in Medicinal Chemistry by Esther Alza Pdf
Learn to master a powerful technology to enable a faster drug discovery workflow The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort. In Flow and Microreactor Technology in Medicinal Chemistry, early adopters of this ground-breaking technology describe its current and potential uses in medicinal chemistry. Based on successful examples of the use of flow and microreactor synthesis for drug-like compounds, the book introduces current as well as emerging uses for automated synthesis in a drug discovery context. Flow and Microreactor Technology in Medicinal Chemistry readers will also find: Numerous case studies that address the most common applications of this technology in the day-to-day work of medicinal chemists How to integrate flow synthesis with drug discovery How to perform enantioselective reactions under continuous flow conditions Flow and Microreactor Technology in Medicinal Chemistry is a valuable practical reference for medicinal chemists, organic chemists, and natural products chemists, whether they are working in academia or in the pharmaceutical industry.
Organized to enable students and synthetic chemists to understand and expand on aromatic reactions covered in foundation courses, the book offers a thorough and accessible mechanistic explanation of aromatic reactions involving arene compounds. • Surveys methods used for preparing arene compounds and their transformations • Connects reactivity and methodology with mechanism • Helps readers apply aromatic reactions in a practical context by designing syntheses • Provides essential information about techniques used to determine reaction mechanisms
Stimulating Concepts in Chemistry by Fritz Vögtle,J. Fraser Stoddart,Masakatsu Shibasaki Pdf
Fresh ideas have always been a necessary ingredient for progress in chemistry. Without a continuous supply of stimulating ideas from creative researchers, there would be no new insights into the subject. But what are some of the ideas that pervade modern chemistry? The answer to this question is to be found in "Stimulating Concepts in Chemistry". In a collection of 24 essays, a group of leading researchers provides an overview of the most recent developments in their fields. Readers can find out about modern concepts in chemistry such as self-assembly, nanochemistry, and molecular machines. Moreover, many spectacular advances have been achieved from the fusion of chemistry with life and materials science - a development which is illustrated by contributions on enzyme mimics, molecular wires, and chemical sensors. Further, the essayists write about new nanomaterials, efficient methods in synthesis, and big biomolecules - indeed, many of the topics that have dominated some of the recent discussions in chemistry. This outstanding text makes use of a special layout to reflect the editors' aim of presenting concepts in the form of essays. Thus, the book is not merely another source of knowledge but is intended to stimulate readers to develop their own ideas and concepts. This format should help to make the book interesting to a wide range of scientists. Students of chemistry will benefit from the different style of presentation of their subject, while researchers in industry and academia will welcome the exciting way in which some of the most challenging concepts in modern chemistry are presented.
Medicinal Chemistry of Neglected and Tropical Diseases by Venkatesan Jayaprakash,Daniele Castagnolo,Yusuf Özkay Pdf
Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.
Author : Andrea T. Da Poian,Miguel A. R. B. Castanho Publisher : Springer Nature Page : 685 pages File Size : 47,7 Mb Release : 2021-01-04 Category : Medical ISBN : 9783030487409
Integrative Human Biochemistry by Andrea T. Da Poian,Miguel A. R. B. Castanho Pdf
This book covers in detail the mechanisms for how energy is managed in the human body. The basic principles that elucidate the reactivity and physical interactions of matter are addressed and quantified with simple approaches. Three-dimensional representations of molecules are presented throughout the book so molecules can be viewed as unique entities in their shape and function. The book is focused on the molecular mechanisms of cellular processes in the context of human physiological situations such as fasting, feeding and physical exercise, in which metabolic regulation is highlighted. Furthermore the book uses key historical experiments that opened up new concepts in biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges. New to this edition: - 30 challenging practical case studies (2-3 at the end of each chapter) based on movies, novels, biographies, documentaries, paintings, and other cultural and artistic creations far beyond canonic academic exercises. - A set of challenging questions and problems in the end of each case study to further engage students with the applications of medical biochemistry - Insights into the answers to the challenging questions to help steer teaching/learning interactions key to productive lectures, PBL (problem-based learning) or traditional tutorials, or e-learning approaches. Advance praise for the second edition: “The Challenging Cases are compelling both from a scientific viewpoint and for the perspective they provide on the history of medicine.” David M. Jameson, University of Hawaii “Using case studies to reinforce the biochemistry lessons is extremely effective – as well as entertaining!” Joseph P. Albanesi, UT Southwestern Medical Center Advance Praise for the first edition: “This textbook provides a modern and integrative perspective of human biochemistry and will be a faithful companion to health science students following curricula in which this discipline is addressed. This textbook will be a most useful tool for the teaching community.” Joan Guinovart Former director of the Institute for Research in Biomedicine, Barcelona, Spain, and former president of the International Union of Biochemistry and Molecular Biology, IUBMB
The Chemical Biology of Nucleic Acids by Günter Mayer Pdf
With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Bridging Traditions by Karen Hunger Parshall,Michael T. Walton,Bruce T. Moran Pdf
Bridging Traditions explores the connections between apparently different zones of comprehension and experience—magic and experiment, alchemy and mechanics, practical mathematics and geometrical mysticism, things earthy and heavenly, and especially science and medicine—by focusing on points of intersection among alchemy, chemistry, and Paracelsian medical philosophy. In exploring the varieties of natural knowledge in the early modern era, the authors pay tribute to the work of Allen Debus, whose own endeavors cleared the way for scholars to examine subjects that were once snubbed as suitable only to the refuse heap of the history of science.
The Chemical Transformations of C1 Compounds by Xiao-Feng Wu,Buxing Han,Kuiling Ding,Zhongmin Liu Pdf
The Chemical Transformations of C1 Compounds A comprehensive exploration of one-carbon molecule transformations The chemistry of one-carbon molecules has recently gained significant prominence as the world transitions away from a petroleum-based economy to a more sustainable one. In The Chemical Transformations of C1 Compounds, an accomplished team of chemists delivers an in-depth overview of recent developments in the field of single-carbon chemistry. The three-volume book covers all major C1 sources, including carbon monoxide, carbon dioxide, methane, methanol, formic acid, formaldehyde, carbenes, C1 halides, and organometallics. The editors have included resources discussing the main reactions and transformations into feedstock chemicals of each of the major C1 compounds reviewed in dedicated chapters. Readers will discover cutting-edge material on organic transformations with MeNO2, DMF, DCM, methyl organometallic reagents, CCl4, CHCl3, and CHBr3, as well as recent achievements in cyanation reactions via cross-coupling. The book also offers: Thorough introductions to chemical transformations of CH4, methods of CH4 activation, chemical transformations of CH3OH and synthesis alkenes from CH3OH Comprehensive explorations of the carbonylation of MeOH, CH2O in organic synthesis, organic transformations of HCO2H, and hydrogen generation from HCO2H Practical discussions of the carbonylation of unsaturated bonds with heterogeneous and homogeneous catalysts, as well as the carbonylation of C(sp2)-X bonds and C(sp3)-X bonds In-depth examinations of carbonylative C-H bond activation and radical carbonylation Perfect for organic and catalytic chemists, The Chemical Transformations of C1 Compounds is also an ideal resource for industrial chemists, chemical engineers, and practitioners at energy supply companies.
MEDICINAL CHEMISTRY- II by Ms. Risha Rajkumar Wale,Moein Sharfodin Attar,Mr. Amol D. Naragude,Mr. Pankaj Vyawhare Pdf
Welcome to the second volume of "Medicinal Chemistry Theory," a comprehensive exploration of the principles and practices that underpin the fascinating field of medicinal chemistry. This volume, Medicinal Chemistry Theory-II, builds upon the foundation laid in the first volume and delves deeper into the intricate world of drug discovery and design. When chemistry, biology, and pharmacology come together, you get medicinal chemistry, a vibrant and interdisciplinary field. Its main purpose is to create new medicines that can be used to treat illnesses and boost people's health. In this volume, we continue our investigation of the molecular interactions that determine the pharmacological activity of substances and its application in drug creation. The discovery of potentially life-saving medications has been greatly aided by the insights gained from medicinal chemistry studies. The work of medicinal chemists is essential in the development of new therapeutics, from small molecule inhibitors to biologics and gene therapies. Structure of the Book: Medicinal Chemistry Theory-II comprises several chapters, each dedicated to a specific aspect of the drug discovery process. We begin with a recap of key concepts from the first volume, providing a seamless transition for readers who may be new to this book series. However, each chapter can also be read independently for those seeking indepth knowledge on particular topics. The chapters in this volume cover a wide range of subjects, including: 1. Drug Metabolism and Pharmacokinetics: Understanding how drugs are metabolized and how their concentration in the body changes over time. 2. Structure-Activity Relationship (SAR) Studies: Exploring the relationship between the chemical structure of compounds and their biological activity. 3. Drug Design Strategies: Examining various approaches employed by medicinal chemists to design novel drugs with enhanced potency and selectivity. 4. Enzyme Inhibitors: Investigating the design and mechanisms of enzyme inhibitors as potential therapeutics
