Author : Ulrich E. Schaible,Albert Haas
Publisher : John Wiley & Sons
Page : 736 pages
File Size : 49,5 Mb
Release : 2009-09-22
Category : Science
ISBN : 9783527629183
Intracellular Niches of Microbes by Ulrich E. Schaible,Albert Haas Pdf
The book describes the different and exciting pathways which havebeen developed by pathogenic microbes to manage living inside hostcells. It covers intracellular life styles of all relevantpathogenic but also symbiotic microorganisms with respect to thecell biology of the host-microbe interactions and the microbialadaptations for intracellular survival. It features intracellulartrafficking pathways and characteristics of intracellular niches ofindividual microbes. The book also asks questions on the benefitsfor the microbe with regard to physiological needs and nutritionalaspects such as auxotrophy, effects on genome sizes, andconsequences for disease and host response/immunity (and thebenefits for the host in the cases of symbionts). Additionally, the book includes those pathogens that are medicallyless important but represent distinct intracellular niches,trafficking behaviours and virulence traits. The individualchapters also point out future challenges of research for therespective organism.