Introduction To Proteins

Author : Amit Kessel,Nir Ben-Tal
Publisher : CRC Press
Page : 985 pages
File Size : 54,8 Mb
Release : 2018-03-22
Category : Computers
ISBN : 9781498747189

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Introduction to Proteins by Amit Kessel,Nir Ben-Tal Pdf

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercises, and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamics and conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary, Exercies, and References Approximately 300 color images Downloadable solutions manual available at www.crcpress.com For more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins' structure and function, please visit the author's website. Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012

Author : Amit Kessel,Nir Ben-Tal
Publisher : CRC Press
Page : 1489 pages
File Size : 48,7 Mb
Release : 2018-03-22
Category : Computers
ISBN : 9781498747219

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Introduction to Proteins by Amit Kessel,Nir Ben-Tal Pdf

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercies, and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamics and conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary, Exercies, and References Approximately 300 color images Downloadable solutions manual available at www.crcpress.com For more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins' structure and function, please visit the author's website: http://ibis.tau.ac.il/wiki/nir_bental/index.php/Introduction_to_Proteins_Book. Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012

Author : Ulo Langel,Benjamin F. Cravatt,Astrid Graslund,N.G.H. von Heijne,Matjaz Zorko,Tiit Land,Sherry Niessen
Publisher : CRC Press
Page : 420 pages
File Size : 49,6 Mb
Release : 2009-11-18
Category : Medical
ISBN : 9781439882047

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Introduction to Peptides and Proteins by Ulo Langel,Benjamin F. Cravatt,Astrid Graslund,N.G.H. von Heijne,Matjaz Zorko,Tiit Land,Sherry Niessen Pdf

Human cells produce at least 30,000 different proteins. Each has a specific function characterized by a unique sequence and native conformation that allows it to perform that function. While research in this post-genomic era has created a deluge of invaluable information, the field has lacked for an authoritative introductory text needed to inform researchers and students in all of those fields now concerned with protein research. Introduction to Peptides and Proteins brings together some of the most respected researchers in protein science to present a remarkably coherent introduction to modern peptide and protein chemistry. The first sections of the book delve into – Basic peptide and protein science from assembly through degradation Traditional and emerging research methods including those used in bioinformatics and proteomics New computational approaches and algorithms used to find patterns in the vast data collected by sequencing projects After providing a foundation in tools and methods, the authors closely examine six protein families, including representative classes such as enzymes, cell-surface receptors, antibodies, fibrous proteins, and bioactive peptide classes. They concentrate on biochemical mechanisms and where possible indicate therapeutic or biotechnical possibilities. Then focusing on clinical aspects, the authors investigate misfolding as found in prion diseases, miscleavage as found in Alzheimer’s, and mis-sequencing as found with some cancers. Drawing from some of their own research, the authors summarize recent achievements and emerging applications. They discuss the use of proteins and peptides as drugs and the solid-phase synthesis required for drug production. They also look at the use of peptides as functional biomolecules and research tools. No longer just the domain of biologists, many key advances in protein research started in physics labs and have involved contributions from a host of fields including statistics, drug development, genetics, and chemical spectroscopy. Introduction to Peptides and Proteins provides researchers across these fields with the thorough foundation needed to explore all the potential that protein research offers.

Author : Amit Kessel,Nir Ben-Tal
Publisher : CRC Press
Page : 654 pages
File Size : 45,5 Mb
Release : 2010-12-17
Category : Medical
ISBN : 1439810729

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Introduction to Proteins by Amit Kessel,Nir Ben-Tal Pdf

As the tools and techniques of structural biophysics assume greater roles in biological research and a range of application areas, learning how proteins behave becomes crucial to understanding their connection to the most basic and important aspects of life. With more than 350 color images throughout, Introduction to Proteins: Structure, Function, and Motion presents a unified, in-depth treatment of the relationship between the structure, dynamics, and function of proteins. Taking a structural–biophysical approach, the authors discuss the molecular interactions and thermodynamic changes that transpire in these highly complex molecules. The text incorporates various biochemical, physical, functional, and medical aspects. It covers different levels of protein structure, current methods for structure determination, energetics of protein structure, protein folding and folded state dynamics, and the functions of intrinsically unstructured proteins. The authors also clarify the structure–function relationship of proteins by presenting the principles of protein action in the form of guidelines. This comprehensive, color book uses numerous proteins as examples to illustrate the topics and principles and to show how proteins can be analyzed in multiple ways. It refers to many everyday applications of proteins and enzymes in medical disorders, drugs, toxins, chemical warfare, and animal behavior. Downloadable questions for each chapter are available at CRC Press Online.

Author : David Whitford
Publisher : John Wiley & Sons
Page : 520 pages
File Size : 50,6 Mb
Release : 2013-04-25
Category : Science
ISBN : 9781118685723

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Proteins by David Whitford Pdf

Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. Opening with a brief historical overview of the subject the book moves on to discuss the ‘building blocks’ of proteins and their respective chemical and physical properties. Later chapters explore experimental and computational methods of comparing proteins, methods of protein purification and protein folding and stability. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of Proteins.

Author : Barry Robson,Jean Garnier
Publisher : Elsevier Publishing Company
Page : 722 pages
File Size : 54,8 Mb
Release : 1988
Category : Science
ISBN : UOM:39015013603850

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Introduction to Proteins and Protein Engineering by Barry Robson,Jean Garnier Pdf

The desire to understand protein structure has been given new impetus by the explosive growth of biotechnology and the important role of proteins, natural and modified, in this technology. Protein molecules are machines, and protein engineering is opening up a whole new world of machinery on the molecular scale. This work is a simple, but in many ways detailed, introduction, to current knowledge, techniques, and applications. The volume is essentially in two parts, the first half covering a basic introduction to proteins appropriate at the undergraduate and early postgraduate level, which will prove a valuable teaching aid. The second half is a more advanced guide to concepts and methods, covering a range of aspects not previously collected in one volume. It will serve as a background reader and guide for advanced research study.

Author : Pradip Kumar Ghosh
Publisher : Academic Press
Page : 312 pages
File Size : 52,9 Mb
Release : 2015-12-10
Category : Science
ISBN : 9780128021125

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Introduction to Protein Mass Spectrometry by Pradip Kumar Ghosh Pdf

Introduction to Protein Mass Spectrometry provides a comprehensive overview of this increasingly important, yet complex, analytical technique. Unlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. Citing the most recent and relevant work in the field of biological mass spectrometry, the book is written for researchers and scientists new to the field, but is also an ideal resource for those hoping to hone their analytical abilities. Offers introductory information for scientists and researchers new to the field, as well as advanced insight into the critical assessment of computer-analyzed mass spectrometric results and their current limitations Provides examples of commonly-used MS instruments from Bruker, Applied Biosystems, JEOL, Thermo Scientific/Thermo Fisher Scientific, IU, and Waters Includes biological applications and exploration of analytical tools and databases for bioinformatics

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Engelbert Buxbaum
Publisher : Springer Science & Business Media
Page : 510 pages
File Size : 48,7 Mb
Release : 2010-11-18
Category : Science
ISBN : 9781441972514

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Biophysical Chemistry of Proteins by Engelbert Buxbaum Pdf

The book is structured in nine sections, each containing several chapters. The volume starts with an overview of analytical techniques and progresses through purification of proteins; protein modification and inactivation; protein size, shape, and structure; enzyme kinetics; protein-ligand interactions; industrial enzymology; and laboratory quality control. The book is targeted at all scientists interested in protein research.

Author : Carl Ivar Branden,John Tooze
Publisher : Garland Science
Page : 424 pages
File Size : 48,7 Mb
Release : 2012-03-26
Category : Science
ISBN : 9781136969898

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Introduction to Protein Structure by Carl Ivar Branden,John Tooze Pdf

The VitalBook e-book of Introduction to Protein Structure, Second Edition is inly available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815323051Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their bio

Author : Dominique Dardevet
Publisher : Academic Press
Page : 368 pages
File Size : 54,9 Mb
Release : 2016-06-08
Category : Health & Fitness
ISBN : 9780128023754

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The Molecular Nutrition of Amino Acids and Proteins by Dominique Dardevet Pdf

The Molecular Nutrition of Amino Acids and Proteins provides an in-depth look at the involvement and role of amino acids and proteins in molecular nutrition. Editor Dominique Dardevet has assembled a collection of chapters written by leading researchers and top professors that provide the reader with a comprehensive understanding of amino acids and proteins. The book provides an introduction to the fundamentals of amino acids and proteins as well as the composition of food. It then delves into the molecular biology of the cell and genetic machinery and its function. The Molecular Nutrition of Amino Acids and Proteins also features reference guides for terms and bullet-point summaries, making it readily accessible to novices while still providing the most up-to-date and detailed information that experienced researchers need. Provides a gentle introduction to the subject by first addressing nutritional information and then building in molecular aspects, clearly establishing fundamental information for the reader Facilitates reader comprehension by including succinct summary points in each chapter Contains a glossary of definitions that allows readers to easily reference terms Provides both a deep and broad understanding of the subject by containing overviews as well as detail-focused chapters

Author : Hans Frauenfelder
Publisher : Springer Science & Business Media
Page : 448 pages
File Size : 49,7 Mb
Release : 2010-05-30
Category : Science
ISBN : 9781441910448

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The Physics of Proteins by Hans Frauenfelder Pdf

Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

Author : Joe Regenstein
Publisher : Elsevier
Page : 368 pages
File Size : 54,9 Mb
Release : 2012-12-02
Category : Technology & Engineering
ISBN : 9780323153867

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Food Protein Chemistry by Joe Regenstein Pdf

Food Protein Chemistry: An Introduction for Food Scientists discusses food proteins and how they are studied. Proteins are both biological entities and physicochemical compounds, and they will be examined in both contexts in this volume. The chemical and physical properties of proteins will be viewed from the perspective of chemists despite the fact that their use in the food supply emphasizes their biological nature. Key topics discussed include proteins as essential to life; amino acids; protein classification; selected proteins of the most important food systems; and protein structure. The book also includes chapters on protein measurement; protein purification; and spectral techniques for the study of proteins. The book requires readers to have the equivalent of the Institute of Food Technologists requirements for undergraduate food science majors. It also assumes a knowledge of math through calculus. While primarily intended for senior and first-year graduate food science students, the text may also be useful to researchers in allied fields.

Author : Arthur M. Lesk
Publisher : Turtleback
Page : 347 pages
File Size : 48,9 Mb
Release : 2000-01-01
Category : Architecture
ISBN : 0613919513

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Introduction To Protein Architecture by Arthur M. Lesk Pdf

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Author : Alexei V. Finkelstein,Oleg Ptitsyn
Publisher : Elsevier
Page : 528 pages
File Size : 54,5 Mb
Release : 2016-06-22
Category : Science
ISBN : 9780081012369

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Protein Physics by Alexei V. Finkelstein,Oleg Ptitsyn Pdf

Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry. Fully revised and expanded new edition based on the latest research developments in protein physics Written by the world's top expert in the field Deals with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states Summarizes, in a systematic form, the results of several decades of worldwide fundamental research on protein physics and their structure and folding Examines experimental data on protein structure in the post-genome era