Ion Mobility Mass Spectrometry

Author : Alison E Ashcroft,Frank Sobott
Publisher : Royal Society of Chemistry
Page : 547 pages
File Size : 50,5 Mb
Release : 2021-11-11
Category : Science
ISBN : 9781839162893

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Ion Mobility-Mass Spectrometry by Alison E Ashcroft,Frank Sobott Pdf

Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields.

Author : G.A. Eiceman,Z. Karpas
Publisher : CRC Press
Page : 367 pages
File Size : 44,6 Mb
Release : 2005-06-23
Category : Science
ISBN : 9781420038972

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Ion Mobility Spectrometry by G.A. Eiceman,Z. Karpas Pdf

Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for the rapid and advanced detection of explosives, chemical and biological warfare agents, and narcotics, ion mobility spectrometry (IMS) undergone significant refinements in technology, computational capabilities, and understanding of the principles of gas phase

Author : G.A. Eiceman,Z. Karpas,Herbert H. Hill, Jr.
Publisher : CRC Press
Page : 444 pages
File Size : 44,5 Mb
Release : 2013-12-10
Category : Science
ISBN : 9781439859988

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Ion Mobility Spectrometry, Third Edition by G.A. Eiceman,Z. Karpas,Herbert H. Hill, Jr. Pdf

Since the turn of the twenty-first century, applications of ion mobility spectrometry (IMS) have diversified, expanding their utility in the military and security spheres and entering the realms of clinical practice and pharmaceutical exploration. Updated and expanded, the third edition of Ion Mobility Spectrometry begins with a comprehensive discussion of the fundamental theory and practice of IMS. Divided into four sections—Overview, Technology, Fundamentals, and Applications—the authors treat innovations and advances in all aspects of IMS in a fresh, thorough, and revised format. Features: Introduces the definitions, theory, and practice of IMS and summarizes its history from the beginnings of the study of ions to present commercial and scholarly activities Presents the technology of IMS from a measurement perspective—covering inlet through ion formation, ion injection, electric fields, drift tube structures, and detectors Covers the end results of measurement, the mobility spectrum, and the transformative trend of ion mobility: mass spectrometry Discusses the influence on the experimental parameters on the mobility of ions Mobility-based methods are no longer restricted to volatile substances and indeed the many benefits of this technology—simplicity, convenience, and the low cost of technology—have become recognized as meritorious in a wide range of uses. This is also true for the advantages of measurements—high speed, distinctive spectral features, and operation in ambient pressure with thermalized ions. Ion Mobility Spectrometry, Third Edition serves specialists in the field of IMS who are interested in the potential of recent developments and researchers, engineers, and students who want a comprehensive overview of this technology.

Author : Charles L. Wilkins,Sarah Trimpin
Publisher : CRC Press
Page : 374 pages
File Size : 46,8 Mb
Release : 2010-12-14
Category : House & Home
ISBN : 9781439813256

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Ion Mobility Spectrometry - Mass Spectrometry by Charles L. Wilkins,Sarah Trimpin Pdf

The analytical power of ion mobility spectrometry-mass spectrometry (IMS-MS) instruments is poised to advance this technology from research to analytical laboratories. Exploring these developments at this critical juncture, Ion Mobility Spectrometry-Mass Spectrometry: Theory and Applications covers the tools, techniques, and applications involved w

Author : Frank Sobott,Alison E. Ashcroft
Publisher : Royal Society of Chemistry
Page : 547 pages
File Size : 54,6 Mb
Release : 2021-11-26
Category : Science
ISBN : 9781839161667

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Ion Mobility-Mass Spectrometry by Frank Sobott,Alison E. Ashcroft Pdf

Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and will help the end users understand the practicalities of using different instruments for different ion mobility purposes.

Author : G.A. Eiceman,Z. Karpas,Herbert H. Hill, Jr.
Publisher : CRC Press
Page : 446 pages
File Size : 40,5 Mb
Release : 2013-12-10
Category : Science
ISBN : 9781439859971

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Ion Mobility Spectrometry, Third Edition by G.A. Eiceman,Z. Karpas,Herbert H. Hill, Jr. Pdf

Since the turn of the twenty-first century, applications of ion mobility spectrometry (IMS) have diversified, expanding their utility in the military and security spheres and entering the realms of clinical practice and pharmaceutical exploration. Updated and expanded, the third edition of Ion Mobility Spectrometry begins with a comprehensive discussion of the fundamental theory and practice of IMS. Divided into four sections—Overview, Technology, Fundamentals, and Applications—the authors treat innovations and advances in all aspects of IMS in a fresh, thorough, and revised format. Features: Introduces the definitions, theory, and practice of IMS and summarizes its history from the beginnings of the study of ions to present commercial and scholarly activities Presents the technology of IMS from a measurement perspective—covering inlet through ion formation, ion injection, electric fields, drift tube structures, and detectors Covers the end results of measurement, the mobility spectrum, and the transformative trend of ion mobility: mass spectrometry Discusses the influence on the experimental parameters on the mobility of ions Mobility-based methods are no longer restricted to volatile substances and indeed the many benefits of this technology—simplicity, convenience, and the low cost of technology—have become recognized as meritorious in a wide range of uses. This is also true for the advantages of measurements—high speed, distinctive spectral features, and operation in ambient pressure with thermalized ions. Ion Mobility Spectrometry, Third Edition serves specialists in the field of IMS who are interested in the potential of recent developments and researchers, engineers, and students who want a comprehensive overview of this technology.

Author : Giuseppe Paglia,Giuseppe Astarita
Publisher : Humana
Page : 312 pages
File Size : 40,5 Mb
Release : 2020-11-15
Category : Science
ISBN : 107160032X

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Ion Mobility-Mass Spectrometry by Giuseppe Paglia,Giuseppe Astarita Pdf

This book focuses on ion mobility-mass spectrometry (IM-MS) and informatics approaches to improve traditional analysis of molecules by providing fundamentals and protocols for exploiting the potential of state-of-the-art IM-MS technology for the most common analytical applications. The chapters have been organized into four parts, each dealing with a particular set of IM-MS applications: 1) metabolomics and lipidomics; 2) proteomics and glycomics; 3) imaging and ambient ionization IM-MS; and 4) bioinformatic solutions for analyzing IM-MS data and deriving CCS values. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Ion Mobility-Mass Spectrometry: Methods and Protocols serves as an ideal resource for scientists delving into the technique's unprecedented analytical advantages, enabling novel qualitative and quantitative applications for the analysis of complex biological samples.

Author : Alexandre A. Shvartsburg
Publisher : CRC Press
Page : 322 pages
File Size : 51,5 Mb
Release : 2008-12-24
Category : Science
ISBN : 1420051075

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Differential Ion Mobility Spectrometry by Alexandre A. Shvartsburg Pdf

Over the last decade, scientific and engineering interests have been shifting from conventional ion mobility spectrometry (IMS) to field asymmetric waveform ion mobility spectrometry (FAIMS). Differential Ion Mobility Spectrometry: Nonlinear Ion Transport and Fundamentals of FAIMS explores this new analytical technology that separates and characterizes ions by the difference between their mobility in gases at high and low electric fields. It also covers the novel topics of higher-order differential IMS and IMS with alignment of dipole direction. The book relates the fundamentals of FAIMS and other nonlinear IMS methods to the physics of gas-phase ion transport. It begins with the basics of ion diffusion and mobility in gases, covering the main attributes of conventional IMS that are relevant to all IMS approaches. Building on this foundation, the author reviews diverse high-field transport phenomena that underlie differential IMS. He discusses the conceptual implementation and first-principles optimization of FAIMS as a filtering technique, emphasizing the dependence of FAIMS performance metrics on instrumental parameters and properties of ion species. He also explores ion reactions in FAIMS caused by field heating and the effects of inhomogeneous electric field in curved FAIMS gaps. Written by an accomplished scientist in the field, this state-of-the-art book supplies the foundation to understand the new technology of nonlinear IMS methods.

Author : Anonim
Publisher : Elsevier
Page : 278 pages
File Size : 44,9 Mb
Release : 2019-01-10
Category : Science
ISBN : 9780444641557

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Advances in Ion Mobility-Mass Spectrometry: Fundamentals, Instrumentation and Applications by Anonim Pdf

Ion Mobility Spectrometry, Volume 83 will focuses on new trends, methods and instrumentation in the field, starting from the innovations of each technique, to the most progressive challenges of IM-MS. Chapters includes section on Recent advances in IM-MS, IM-MS Principles and Theory, IM-MS Applications and Instrumentation, and the Future of IM-MS. Presents the latest advancements in IM-MS that are essential for new applications Helps readers understand the state-of-the-art in the currently available IM-MS interfaces and their principle uses Provides information on different IM-MS instrumentation Delves into key applications of IM-MS

Author : Giuseppe Paglia,Giuseppe Astarita
Publisher : Unknown
Page : 312 pages
File Size : 42,7 Mb
Release : 2020
Category : Biochemistry
ISBN : 1071600311

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Ion Mobility-Mass Spectrometry by Giuseppe Paglia,Giuseppe Astarita Pdf

This book focuses on ion mobility-mass spectrometry (IM-MS) and informatics approaches to improve traditional analysis of molecules by providing fundamentals and protocols for exploiting the potential of state-of-the-art IM-MS technology for the most common analytical applications. The chapters have been organized into four parts, each dealing with a particular set of IM-MS applications: 1) metabolomics and lipidomics; 2) proteomics and glycomics; 3) imaging and ambient ionization IM-MS; and 4) bioinformatic solutions for analyzing IM-MS data and deriving CCS values. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Ion Mobility-Mass Spectrometry: Methods and Protocols serves as an ideal resource for scientists delving into the technique's unprecedented analytical advantages, enabling novel qualitative and quantitative applications for the analysis of complex biological samples.

Author : Gary A. Eiceman,Zeev Karpas
Publisher : CRC-Press
Page : 240 pages
File Size : 55,5 Mb
Release : 1993-11-30
Category : Science
ISBN : 084934235X

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Ion Mobililty Spectrometry by Gary A. Eiceman,Zeev Karpas Pdf

Chronicles the development of ion mobility spectrometry (IMS) from its inception two decades ago to current applications and plans for the future. Fundamental aspects of atmospheric pressure ion processes and their chemical ionization effect on the response characteristics of IMS are analyzed. The theory and physics governing the motion of ions drifting through an atmospheric pressure buffer gas in an electric field are presented in a simplified yet comprehensive manner. The book also presents an up-to-date report on recent developments and applications in IMS instrumentation, including laboratory instruments, monitoring systems, and hand-held instrumentation. The performance of GC/ IMS is analyzed and critically evaluated, and tables of reliable reducer mobility values are provided.

Author : T.W. Carr
Publisher : Springer
Page : 284 pages
File Size : 46,8 Mb
Release : 1984-03-31
Category : Science
ISBN : UCAL:B4477442

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Plasma Chromatography by T.W. Carr Pdf

Author : Earl Wadsworth McDaniel
Publisher : John Wiley & Sons
Page : 408 pages
File Size : 55,7 Mb
Release : 1970
Category : Science
ISBN : UOM:39015001334336

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Ion-molecule Reactions by Earl Wadsworth McDaniel Pdf

Author : Kenneth W. Busch,Marianna A. Busch
Publisher : Elsevier
Page : 720 pages
File Size : 47,8 Mb
Release : 2011-10-13
Category : Science
ISBN : 0080469280

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Chiral Analysis by Kenneth W. Busch,Marianna A. Busch Pdf

Chiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained. * Broad coverage - spectroscopic and separation methods covered in a single volume * Up-to-date and detailed review of the various techniques available and/or under development in this field * Contributions from leading experts in the field

Author : Zane Baird
Publisher : Springer
Page : 65 pages
File Size : 50,8 Mb
Release : 2016-12-08
Category : Science
ISBN : 9783319498690

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Manipulation and Characterization of Electrosprayed Ions Under Ambient Conditions by Zane Baird Pdf

This thesis addresses the evolving field of measurement science, specifically that of mass spectrometry (MS) and ion mobility spectrometry (IMS) based techniques. It focuses on the design, construction and implementation of low-cost, easy-to-manufacture measurement tools that are used in modern settings such as airport security screening. Advances in these technologies often involve minimal performance enhancement at ever-increasing cost, which in turn limits accessibility to versatile measurement tools. This problem is addressed using desktop 3D printers along with widely available materials for the production of novel ion lenses and an IMS instrument with a performance comparable to that of many commercial systems. Baird ́s findings are a source of inspiration for scientists exploring this emerging field./div