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Author : George Bennett LaMotte
Publisher : Unknown
Page : 228 pages
File Size : 44,5 Mb
Release : 1979
Category : Blood proteins
ISBN : CORNELL:31924000636682
Author : Paul-Pierre Pastoret
Publisher : Academic Press
Page : 699 pages
File Size : 44,9 Mb
Release : 1998-06-02
Category : Medical
ISBN : 9780125464017
This unique book provides a comprehensive and comparative guide to the immune systems of major vertebrate species, including domestic and wild animals of veterinary or medical interest, fish and amphibia. Data in this essential reference work has been compiled by world-renowned editors and an international group of authors. For each species, the information is presented in a structured 'user-friendly' format allowing easy cross reference and comparison between the various species. This book will be considered the definitive reference work on vertebrate immunology and will be essential for scientists and professionals working in Immunology, Vaccinology or with Animal Models, for students of Veterinary or Human Medicine, Biology and researchers in Comparative Medicine and Physiology. Each section, devoted to a major animal group covers: Lymphoid organs and their anatomical disposition Leukocytes and their markers Leukocyte traffic and associated molecules Cytokines T cell receptors Immunoglobulins MHC antigens Ontogeny of the immune system Passive transfer of immunity Neonatal immune responses Non-specific immunity Complement system Mucosal immunity Immunodeficiencies Tumours of the immune system Autoimmunity
Author : Anonim
Publisher : Unknown
Page : 1828 pages
File Size : 40,6 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864997
Author : Ian R. Tizard
Publisher : Elsevier Health Sciences
Page : 615 pages
File Size : 43,8 Mb
Release : 2012-05-17
Category : Medical
ISBN : 9781455703630
The only complete resource on immunology for veterinary students and practitioners, Veterinary Immunology: An Introduction features a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts. Comprehensive coverage of vaccines and vaccine usage, allergies and allergic diseases, and autoimmunity and immunodeficiencies, prepare you for the multiple immunologic issues you will encounter in practice. A wealth of clinical examples clearly illustrate key concepts and offer practical strategies for diagnosing and treating immunologic disorders in the clinical setting. More than 500 full-color diagrams and illustrations visually demonstrate and clarify complex issues. Completely updated section on innate immunity includes new chapters on natural killer (NK) cells and systemic responses to infection to ensure you have the most up-to-date information. New information on genomics and molecular diagnostic techniques explores how the emerging field of genomics impacts disease resistance and immunology in general, as well as the diagnosis and treatment of immunological and infectious diseases. Updated content provides new information on well-recognized older diseases such as rheumatoid arthritis, systemic lupus, and inflammatory bowel disease, as well as current information on new diseases such as devil facial tumor disease and bovine neonatal pancytopenia. Expanded coverage brings you the latest knowledge on resistance to infection, such as vaccine usage, especially with respect to duration of immunity, the effects of key vitamins and lipids on immune responses, the effects of old age on immunity, and both antiviral and parasitic immunity. Diagnostic tests described throughout the text include a new section on the analysis of ELISA test data, as well as a brief summary of molecular diagnostic techniques. Coverage reflecting a significant change in the overall view of immunology provides you with the foundational knowledge needed to grasp the broad pattern of immunologic reactions and understand how the immune system functions as an interconnected network, rather than a series of independent pathways. New discussions of the critical importance of commensal bacteria and intestinal flora explain help you understand the importance of this normal flora with respect to antibacterial immunity, allergies, and autoimmunity, while at the same time providing a broader view of the animal body and its microflora as a "superorganism." A discussion of the importance of adipose tissue in immunity and inflammation addresses the epidemic of obesity in domestic pets and the extraordinary growth rates expected of domestic livestock. The section on inflammatory mechanisms has been divided into separate chapters focusing on the detection of invaders and the mediators of inflammation to incorporate the vast amount of new information on pattern recognition receptors and the ways in which they warn the body of microbial invasion.
Author : Ian R. Tizard
Publisher : Elsevier Health Sciences
Page : 568 pages
File Size : 41,5 Mb
Release : 2013-12-27
Category : Medical
ISBN : 9780323291699
The only complete resource on immunology for veterinary students and practitioners, Veterinary Immunology: An Introduction features a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts. Comprehensive coverage of vaccines and vaccine usage, allergies and allergic diseases, and autoimmunity and immunodeficiencies, prepare you for the multiple immunologic issues you will encounter in practice. A wealth of clinical examples clearly illustrate key concepts and offer practical strategies for diagnosing and treating immunologic disorders in the clinical setting. More than 500 full-color diagrams and illustrations visually demonstrate and clarify complex issues. Completely updated section on innate immunity includes new chapters on natural killer (NK) cells and systemic responses to infection to ensure you have the most up-to-date information. New information on genomics and molecular diagnostic techniques explores how the emerging field of genomics impacts disease resistance and immunology in general, as well as the diagnosis and treatment of immunological and infectious diseases. Updated content provides new information on well-recognized older diseases such as rheumatoid arthritis, systemic lupus, and inflammatory bowel disease, as well as current information on new diseases such as devil facial tumor disease and bovine neonatal pancytopenia. Expanded coverage brings you the latest knowledge on resistance to infection, such as vaccine usage, especially with respect to duration of immunity, the effects of key vitamins and lipids on immune responses, the effects of old age on immunity, and both antiviral and parasitic immunity. Diagnostic tests described throughout the text include a new section on the analysis of ELISA test data, as well as a brief summary of molecular diagnostic techniques. Coverage reflecting a significant change in the overall view of immunology provides you with the foundational knowledge needed to grasp the broad pattern of immunologic reactions and understand how the immune system functions as an interconnected network, rather than a series of independent pathways. New discussions of the critical importance of commensal bacteria and intestinal flora explain help you understand the importance of this normal flora with respect to antibacterial immunity, allergies, and autoimmunity, while at the same time providing a broader view of the animal body and its microflora as a "superorganism." A discussion of the importance of adipose tissue in immunity and inflammation addresses the epidemic of obesity in domestic pets and the extraordinary growth rates expected of domestic livestock. The section on inflammatory mechanisms has been divided into separate chapters focusing on the detection of invaders and the mediators of inflammation to incorporate the vast amount of new information on pattern recognition receptors and the ways in which they warn the body of microbial invasion.
Author : Klaus Rother,Gerd O. Till
Publisher : Springer Science & Business Media
Page : 549 pages
File Size : 44,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642970382
Upon contemplating an updated version of the 1974 edition of this book and envisioning its possible organization, it immediately became evident that the new version could no longer be written by one, two, or even three authors. The field has experienced an explosive expansion in various directions, and the wealth of newer data which has been accumulated over the last decade can hardly be presented by a single author in a critical and coherent manner. On the other hand, it appears worthwhile not to abandon the attempt to come foreward with a review which describes as comprehensively as possible the progress and the state of knowledge. It is the aim of this volume to present a general and comprehensive review on complement. It is intended not only for individuals working in this area, but also for those who are less familiar with the field. Several chapters in the book describe state-of-the-art experimental methods which are helpful to critically evaluate the experimental data. Simultaneously, they may provide the necessary technical tools for those who wish to enter this highly provocative and exciting field.
Author : R. Pandey
Publisher : S. Karger AG (Switzerland)
Page : 240 pages
File Size : 47,8 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015010127879
Author : David M. Kurtz,Gregory S. Travlos
Publisher : CRC Press
Page : 1685 pages
File Size : 52,6 Mb
Release : 2017-10-18
Category : Medical
ISBN : 9781351643092
Key features: Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics Provides extensive reference lists at the end of each chapter to facilitate further study Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems. Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed. New Chapters in the Third Edition Include: The Laboratory Zebrafish and Other Fishes Evaluation of Cardiovascular and Pulmonary Function and Injury Evaluation of Skeletal Muscle Function and Injury Evaluation of Bone Function and Injury Vitamins Development of Biomarkers Statistical Methods The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species.
Author : John D. Lambris
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 48,8 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9783642749773
The third component of complement, C3, is one of the most versatile proteins and an important participant in immune surveillance and immune response pathways. Its multifunctio nality is based on its ability to interact specifically with multiple serum complement proteins, cell surface receptors, and mem brant;-associated regulatory proteins. One of its most intriguing strategies of interaction with cell surfaces is the covalent binding of activated C3 through the internal thioester. The field has expanded over the past 10 years and a wealth of information has accumulated. C3 from various species and many of the human C3 binding proteins have been cloned and expressed. Numerous cellular responses mediated by the diffe rent fragments of C3 have been described. The findings that C3 interacts in a ligand-receptor-like fashion with proteins of nonself origin such as the gC of herpes simplex virus, a 70-kDa protein from Candida albicans, proteins from Epstein-Barr virus, etc. has opened a new field of investigation. The papers assembled in this volume summarize the wealth of data on the various aspects of the C3 interactions; together they bring to the reader new information on the chemistry, molecular gene tics, biology, and pathophysiology of C3 and C3-binding proteins. Emphasis is given to structural features as they relate to functions. Spring 1989 JOHN D. LAMBRIS, HANS J. MULLER-EBERHARD Table of Contents J. E. VOLANAKIS: Participation of C3 and Its Ligands in Complement Activation . . . . . . . . . . . 1 S. R. BARNUM, G. FEY, and B. F. TACK: Biosynthesis and Genetics of C3 . . . . . . . . . . . . .
Author : Robert B. Sim
Publisher : Springer Science & Business Media
Page : 243 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401127578
The complement system is a group of proteins which plays a major role in the processing and removal of microorganisms and tissue breakdown products from the circulation and extracellular spaces. The system is activated by a wide range of targets, and activation leads to the production of opsonins, chemotaxis of granulocytes, cell lysis and other biological activities. Inappropriate overactivation of the system contributes to inflammatory tissue damage in the host, while inadequate activation leads to accumulation of immune complexes and other debris in the circulation, and susceptibility to infection. The biology and biochemistry of the system is now adequately understood, and attempts can be made to manipulate the activation and activities of the system for potential therapeutic purposes. The reviews in this volume summarise what is known of the ways in which the complement system can be activated, by interaction with antibodies, microorganisms, cell debris, and complex carbohydrates and how the activities and activation of the system have been modified, accidentally or by design, in vitro or in vivo by drugs, venoms, particulate carbohydrates, specific antibodies, synthetic peptides and other reagents.
Author : Anonim
Publisher : Unknown
Page : 858 pages
File Size : 50,9 Mb
Release : 2003
Category : Veterinary medicine
ISBN : UCD:31175028821968
Vols. for 1956- include selected papers from the proceedings of the American Veterinary Medical Association.
Author : Keith Whaley
Publisher : Unknown
Page : 348 pages
File Size : 50,8 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015010127911
Author : Federation of American Societies for Experimental Biology
Publisher : Unknown
Page : 1584 pages
File Size : 51,5 Mb
Release : 1981
Category : Biochemistry
ISBN : UVA:X001678128
Vols. for 1942- include proceedings of the American Physiological Society.
Author : Mrinal K. Dewanjee
Publisher : Springer Science & Business Media
Page : 627 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461535089
Among the readily available -emitting radionuclides, the nuclides of iodine have the greatest versatility in labeling both the hydrophilic and the lipophilic compounds that are used in biology and medicine. Biologically important micrmolecules, semimacromolecules, and macromolecules have been identified which, after iodination, almost maintain the same molecular configuration and similar biologic specificity as those of the parent molecules. The multiple techniques for iodination and the clinical use of iodinated products have made possible the present status of the development of diagnostic nuclear medicine. 125r, with a half-life of 60 days, has a crucial role in competitive protein-binding studies. 131r is useful for measuring thyroid uptake, for the diagnosis of thyroid carcinoma and metastasis, and for therapy. 1nr , with a reasonably shorter half-life, is almost ideal for thyroid workup and for a few useful labeled radiopharmaceutical. Although ~c is used more widely in diagnostic procedures, the radionuclides of iodine will always have a major role in biology and medicine. A considerable amount of information is scattered in the literature regarding the chemistry of radioiodination and the mechanism of tracer localization in cells and tissues. Labeled peptides, proteins, and antibodies are extensively used for protein turnover studies, receptor binding and tumor imaging studies, and radioimmunoassay. The general trend in the use of tracers in clinical nuclear medicine has been an evolution from 3H, 14C, 11C, and 13 to 125 , 131 and 123r to ~c and 111rn.
Author : Anonim
Publisher : Unknown
Page : 824 pages
File Size : 46,5 Mb
Release : 1997
Category : Dissertations, Academic
ISBN : STANFORD:36105020770017
