The Third Component Of Complement

Author : John D. Lambris
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 48,6 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9783642749773

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The Third Component of Complement by John D. Lambris Pdf

The third component of complement, C3, is one of the most versatile proteins and an important participant in immune surveillance and immune response pathways. Its multifunctio nality is based on its ability to interact specifically with multiple serum complement proteins, cell surface receptors, and mem brant;-associated regulatory proteins. One of its most intriguing strategies of interaction with cell surfaces is the covalent binding of activated C3 through the internal thioester. The field has expanded over the past 10 years and a wealth of information has accumulated. C3 from various species and many of the human C3 binding proteins have been cloned and expressed. Numerous cellular responses mediated by the diffe rent fragments of C3 have been described. The findings that C3 interacts in a ligand-receptor-like fashion with proteins of nonself origin such as the gC of herpes simplex virus, a 70-kDa protein from Candida albicans, proteins from Epstein-Barr virus, etc. has opened a new field of investigation. The papers assembled in this volume summarize the wealth of data on the various aspects of the C3 interactions; together they bring to the reader new information on the chemistry, molecular gene tics, biology, and pathophysiology of C3 and C3-binding proteins. Emphasis is given to structural features as they relate to functions. Spring 1989 JOHN D. LAMBRIS, HANS J. MULLER-EBERHARD Table of Contents J. E. VOLANAKIS: Participation of C3 and Its Ligands in Complement Activation . . . . . . . . . . . 1 S. R. BARNUM, G. FEY, and B. F. TACK: Biosynthesis and Genetics of C3 . . . . . . . . . . . . .

Author : John D. Lambris
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 1990
Category : Electronic
ISBN : OCLC:636775281

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The Third Component of Complement by John D. Lambris Pdf

Author : Cynthia C. Chernecky,Barbara J. Berger
Publisher : Elsevier Health Sciences
Page : 1235 pages
File Size : 42,6 Mb
Release : 2012-12-01
Category : Medical
ISBN : 9781455745029

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Laboratory Tests and Diagnostic Procedures by Cynthia C. Chernecky,Barbara J. Berger Pdf

Find complete answers to questions such as which laboratory tests to order or what the results might mean. Laboratory Tests and Diagnostic Procedures, 6th Edition covers more tests than any other reference of its kind, with over 900 lab tests and diagnostic procedures in all. In Part I, you'll find an alphabetical list of hundreds of diseases, conditions, and symptoms, including the tests and procedures most commonly used to confirm or rule out a suspected diagnosis. In Part II, you’ll find descriptions of virtually every laboratory and diagnostic test available. This edition is updated with the latest research and over 20 NEW test entries. Written by educator Cynthia Chernecky and clinical nurse specialist Barbara Berger, this lab reference covers today’s lab tests with concise, easy-to-use information. More than 900 laboratory tests and diagnostic procedures are included — more than any other reference! Over 600 diseases, conditions, and symptoms are listed, along with the tests used to confirm them. Alphabetical organization and A-to-Z thumb tabs make it easy to find the information you’re looking for. Alternative test names and acronyms are cross-referenced to simplify lookup. Instructions for client and family teaching help you offer guidance concerning test preparation and follow-up care. Age and gender-specific norms are provided, giving you complete lifespan coverage. Risks and Contraindications are highlighted to help you safeguard your patients and provide effective care. Panic Level Symptoms and Treatment are provided for dangerously increased and decreased levels. Minimum volumes for blood samples are included, useful when a client’s blood preservation is essential, as well as information on whether blood specimens can be drawn during hemodialysis. Tests for toxic substances are included, making this a lab, diagnostic, and toxicology book all in one. Abbreviations, measurement prefixes, and symbols are listed on the front and back covers for convenience. Information on herbal supplements indicates when a client’s use of natural remedies might affect test results. Over 20 NEW test entries present the latest tests and procedures, with a strong focus on affordable, clinically relevant genetic tests. UPDATED content includes the latest research relating to accuracy of tests, diagnostic value of results, and associated cost-benefit ratios.

Author : Roald Nezlin
Publisher : Academic Press
Page : 269 pages
File Size : 50,8 Mb
Release : 1998-05-06
Category : Science
ISBN : 008053452X

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The Immunoglobulins by Roald Nezlin Pdf

This book provides comprehensive up-to-date information on the structure and function of immunoglobulins. It describes the basic features of these molecules, which assists the reader in understanding how they function as an integral part of the immune system. The Immunoglobulins describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis of latest x-ray crystallography studies. It discusses recently developed biotechnological methods that allow scientists to obtain fully active antibody molecules in vitro even without immunization and to construct new variants of immunoglobulins and their fragments by fusing with various other active molecules. A survey of recent knowledge on immunoglobulin-binding molecules other than antigens and on flexibility of immunoglobulin molecules concludes the discussion of functional aspects of the problem. Describes recent reviews on the structure and function of immunoglobulin molecules of various species Summarizes in detail recent findings on the fine structure of the antigen-combining site Presents comparative data on the antigen-recognizing sites of other molecules such as MHC proteins and T-cell receptors Summarizes growing data on immunoglobulin binding sites responsible for the reaction of immunoglobulins with molecules other than antigens Explores the rapid advance of recent biotechnological methods used for the construction of antibody molecules and their fragments with new properties Presents extensive references and is lavishly illustrated

Author : George Bennett LaMotte
Publisher : Unknown
Page : 228 pages
File Size : 44,8 Mb
Release : 1979
Category : Blood proteins
ISBN : CORNELL:31924000636682

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Isolation and Characterization of the Third Component of Bovine Complement by George Bennett LaMotte Pdf

Author : Mihaela Gadjeva
Publisher : Humana
Page : 0 pages
File Size : 53,7 Mb
Release : 2016-08-23
Category : Medical
ISBN : 1493963066

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The Complement System by Mihaela Gadjeva Pdf

Complement Systems: Methods and Protocols is composed of 32 individual chapters that describe a variety of protocols to purify and analyze the activity of the individual complement components or pathways. It includes assays that describe detection of complement SNPs, clinical methods to evaluate complement system activation and data interpretation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Complement Systems: Methods and Protocols provides a collection of well-established “classical” assays and recently developed “new” assays to analyze the complement system activation will be useful to a wide audience of scientists.

Author : Anonim
Publisher : Unknown
Page : 1916 pages
File Size : 55,7 Mb
Release : 1997
Category : Medicine
ISBN : OSU:32436010520441

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Cumulated Index Medicus by Anonim Pdf

Author : Holger Heine
Publisher : Springer Science & Business Media
Page : 248 pages
File Size : 55,5 Mb
Release : 2007-12-07
Category : Science
ISBN : 9783540739302

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Innate Immunity of Plants, Animals and Humans by Holger Heine Pdf

This book has been cunningly designed to provide an overview of our current knowledge about the innate immune systems of these three types of organisms. It not only covers the innate immune mechanisms and responses of such diverse organisms as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans. It delves too into the central defense mechanisms, antimicrobial peptides and the complement system.

Author : M. Benczur,Anna Erdei,A. Falus,G. Füst,G.A. Medgyesi,G.G. Petranyi,Eva Rajnavölgyi
Publisher : Springer
Page : 926 pages
File Size : 54,6 Mb
Release : 2013-12-21
Category : Medical
ISBN : 9783642514791

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Progress in Immunology Vol. VIII by M. Benczur,Anna Erdei,A. Falus,G. Füst,G.A. Medgyesi,G.G. Petranyi,Eva Rajnavölgyi Pdf

At this congress there were again numereous reports of progress in immunology. The new technologies are continuing to have an immense impact: gene isolation, mutation, transfection and expression, protein structure andpeptide synthesis, cell cloning, hybridization and monoclonal antibodies, CD serology, SCID and transgenic mice, modern immunomodulation and vaccines. A trmendous mass of data has accumulated over the last years. The reports are up-to-date and outstanding,to a degree no journal will ever achieve, and the results are presented in a concise and lucid way. This report will serve as a guideline for the years to came, because it is a treasure trove of explorations, making it exciting reading. This progress presents outstanding contributions. Immunology is exhibited at its best: an exciting research area and a rewarding subject to study for the benefit of mankind - today more than ever.

Author : Julius M. Cruse MD PhD,Robert E. Lewis
Publisher : CRC Press
Page : 857 pages
File Size : 44,5 Mb
Release : 2003-12-29
Category : Medical
ISBN : 9781420039948

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Atlas of Immunology by Julius M. Cruse MD PhD,Robert E. Lewis Pdf

With more than 1100 computer-generated figures, line drawings, and photographs, Atlas of Immunology clearly demonstrates thata picture is worth a thousand words. Written for students, basic scientists, and clinicians, this second edition provides a thorough and up-to-date treatment of all the concepts needed to comprehend contemporary imm

Author : Walter Reed Army Institute of Research
Publisher : Unknown
Page : 890 pages
File Size : 51,5 Mb
Release : 1949
Category : Biochemistry
ISBN : OSU:32436000909299

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Basic Science Notes by Walter Reed Army Institute of Research Pdf

Author : Donald Y. M. Leung,Hugh Sampson,Raif Geha,Stanley J. Szefler
Publisher : Elsevier Health Sciences
Page : 705 pages
File Size : 48,8 Mb
Release : 2010-10-13
Category : Medical
ISBN : 9781437737783

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Pediatric Allergy: Principles and Practice E-Book by Donald Y. M. Leung,Hugh Sampson,Raif Geha,Stanley J. Szefler Pdf

Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.

Author : Klaus Rother,Gerd O. Till
Publisher : Springer Science & Business Media
Page : 549 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642970382

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The Complement System by Klaus Rother,Gerd O. Till Pdf

Upon contemplating an updated version of the 1974 edition of this book and envisioning its possible organization, it immediately became evident that the new version could no longer be written by one, two, or even three authors. The field has experienced an explosive expansion in various directions, and the wealth of newer data which has been accumulated over the last decade can hardly be presented by a single author in a critical and coherent manner. On the other hand, it appears worthwhile not to abandon the attempt to come foreward with a review which describes as comprehensively as possible the progress and the state of knowledge. It is the aim of this volume to present a general and comprehensive review on complement. It is intended not only for individuals working in this area, but also for those who are less familiar with the field. Several chapters in the book describe state-of-the-art experimental methods which are helpful to critically evaluate the experimental data. Simultaneously, they may provide the necessary technical tools for those who wish to enter this highly provocative and exciting field.

Author : Ian R. Mackay,Noel R. Rose
Publisher : Unknown
Page : 128 pages
File Size : 47,8 Mb
Release : 2019
Category : Clinical immunology
ISBN : 1461492092

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Encyclopedia of Medical Immunology by Ian R. Mackay,Noel R. Rose Pdf

Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: • A list of the vaccines currently available along with a list of the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 52,9 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.