Isonitrile Chemistry

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Isonitrile Chemistry

Author : Ivar Ugi
Publisher : Elsevier
Page : 293 pages
File Size : 49,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323157339

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Isonitrile Chemistry by Ivar Ugi Pdf

Organic Chemistry, Volume 20: Isonitrile Chemistry discusses the fundamental aspects of the chemistry of isonitriles. This book provides an introduction to as well as a thorough coverage of isonitrile chemistry. Organized into 10 chapters, this volume begins with an overview of the general properties and structure of isonitriles. This text then examines the quantitative study of the kinetics of isonitrile rearrangement as well as the principal resonance structure of the isonitrile molecule. Other chapters consider the experimental and theoretical findings on the fall-off behavior of the unimolecular rate constants of different isonitriles with pressure. This book discusses as well the behavior of isonitriles toward a center of low electron density, which is particularly manifested in the reactivity of alkyl and aryl isonitriles toward diborane and alkyl or arylboranes. The final chapter deals with the inorganic coordination chemistry of isonitriles. This book is a valuable resource for organic chemists.

Isocyanide Chemistry

Author : V. Nenajdenko
Publisher : John Wiley & Sons
Page : 615 pages
File Size : 47,8 Mb
Release : 2012-06-04
Category : Science
ISBN : 9783527652556

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Isocyanide Chemistry by V. Nenajdenko Pdf

The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in different branches of organic, inorganic, coordination, combinatorial and medicinal chemistry. This invaluable reference is the only book to cover the topic in such depth, presenting all aspects of synthetic isonitrile chemistry. The highly experienced and internationally renowned editor has brought together an equally distinguished team of authors who cover multicomponent reactions, isonitriles in total synthesis, isonitriles in polymer chemistry and much more.

March's Advanced Organic Chemistry

Author : Michael B. Smith
Publisher : John Wiley & Sons
Page : 2146 pages
File Size : 41,8 Mb
Release : 2020-02-19
Category : Science
ISBN : 9781119371809

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March's Advanced Organic Chemistry by Michael B. Smith Pdf

The completely revised and updated, definitive resource for students and professionals in organic chemistry The revised and updated 8th edition of March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure explains the theories of organic chemistry with examples and reactions. This book is the most comprehensive resource about organic chemistry available. Readers are guided on the planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions The opening chapters of March's Advanced Organic Chemistry, 8th Edition deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered. The final chapters cover the nature and scope of organic reactions and their mechanisms. This edition: Provides revised examples and citations that reflect advances in areas of organic chemistry published between 2011 and 2017 Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds prepared Instructs the reader on preparing and conducting multi-step synthetic reactions, and provides complete descriptions of each reaction The 8th edition of March's Advanced Organic Chemistry proves once again that it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Winner of the Textbook & Acadmic Authors Association 2021 McGuffey Longevity Award.

Basic Organometallic Chemistry

Author : Ionel Haiduc,Jerry J. Zuckerman
Publisher : Walter de Gruyter
Page : 517 pages
File Size : 52,7 Mb
Release : 2011-06-01
Category : Science
ISBN : 9783110847888

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Basic Organometallic Chemistry by Ionel Haiduc,Jerry J. Zuckerman Pdf

Studies in Natural Products Chemistry

Author : Atta-ur Rahman
Publisher : Elsevier
Page : 547 pages
File Size : 43,8 Mb
Release : 2015-01-20
Category : Science
ISBN : 9780444634702

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Studies in Natural Products Chemistry by Atta-ur Rahman Pdf

Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Combinatorial Chemistry

Author : Günther Jung
Publisher : John Wiley & Sons
Page : 634 pages
File Size : 42,9 Mb
Release : 2008-07-11
Category : Science
ISBN : 9783527613519

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Combinatorial Chemistry by Günther Jung Pdf

The story of success goes on and on - with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Gunther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry. This is the book written by specialists for specialists and for everyone aspiring to become an insider! It is an indispensible source of information for researchers working in organic synthesis, catalysis, biochemistry, and biotechnology, pharmaceutical and clinical chemistry, material sciences, and analytical chemistry.

Organic Functional Group Preparations

Author : Stanley R. Sandler,Wolf Karo
Publisher : Academic Press
Page : 567 pages
File Size : 44,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780080925585

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Organic Functional Group Preparations by Stanley R. Sandler,Wolf Karo Pdf

This volume provides organic chemists with a convenient, up-to-date reference source on reliable preparative procedures for the most common functional groups. Preparations for each functional group have been subdivided into various reaction types.

Isocyanide-based Multicomponent Reactions

Author : Jonathan G. Rudick,Alexander Dömling,Shabnam Shaabani
Publisher : Frontiers Media SA
Page : 100 pages
File Size : 42,7 Mb
Release : 2020-02-20
Category : Electronic
ISBN : 9782889634842

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Isocyanide-based Multicomponent Reactions by Jonathan G. Rudick,Alexander Dömling,Shabnam Shaabani Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Reagents for Radical and Radical Ion Chemistry

Author : David Crich
Publisher : John Wiley & Sons
Page : 1874 pages
File Size : 42,8 Mb
Release : 2013-05-30
Category : Science
ISBN : 9781118634899

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Reagents for Radical and Radical Ion Chemistry by David Crich Pdf

Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.

Combinatorial Chemistry and Technologies

Author : Stanislav Miertus,Giorgio Fassina
Publisher : CRC Press
Page : 616 pages
File Size : 41,6 Mb
Release : 2005-04-12
Category : Medical
ISBN : 9780824758370

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Combinatorial Chemistry and Technologies by Stanislav Miertus,Giorgio Fassina Pdf

Several books on the market cover combinatorial techniques, but they offer just a limited perspective of the field, focusing on selected aspects without examining all approaches and integrated technologies. Combinatorial Chemistry and Technologies: Methods and Applications answers the demand for a complete overview of the field, covering all of the methodologies used in the design, synthesis, and screening of molecular libraries. Now in its second edition, this volume updates prior content and explores new areas such as catalysis, applications in biotechnology, and current ICS-UNIDO activities. Topics include the generation of molecular diversity by chemical methods using solution- and solid-phase chemistries, biological approaches for the production and screening of peptides, antibody and oligonucleotide libraries, and the application of computer-assisted approaches to guide library synthesis. The book establishes the link between combinatorial chemistry and molecular modeling and illustrates the importance of economics and patenting in combinatorial technologies. Valuable to technologists and researchers as an introductory survey on the many aspects of combinatorial chemistry and combinatorial technology, Combinatorial Chemistry and Technologies: Methods and Applications offers an overview of a field that promises broad applicability in the identification of new drugs, as well as in diagnostics, new materials, and catalysis.

Combinatorial Chemistry and Technology

Author : Stanislav Miertus,Giorgio Fassina
Publisher : CRC Press
Page : 456 pages
File Size : 54,9 Mb
Release : 1999-07-01
Category : Science
ISBN : 142000056X

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Combinatorial Chemistry and Technology by Stanislav Miertus,Giorgio Fassina Pdf

"Provides comprehensive coverage of the current combinatorial methodologies and technologies employed for the design, synthesis, and screening of molecular ""libraries."" Features assessments of computer-assisted approaches to guiding library synthesis. Designed to satisfy the demand to create, produce in high yield and purity, and rapidly screen huge numbers of molecules."

Organic Synthesis

Author : Michael B Smith
Publisher : Academic Press
Page : 1106 pages
File Size : 46,7 Mb
Release : 2016-11-22
Category : Science
ISBN : 9780128008072

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Organic Synthesis by Michael B Smith Pdf

Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. PowerPoint© presentations and answer keys are also available online to support instructors. Fully revised and updated throughout, and teorganized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Lecture presentations and other useful material for qualified course instructors

Combinatorial Chemistry

Author : Stephen R. Wilson,Anthony W. Czarnik
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 51,9 Mb
Release : 1997-03-28
Category : Medical
ISBN : 047112687X

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Combinatorial Chemistry by Stephen R. Wilson,Anthony W. Czarnik Pdf

The new time-saving revolution in drug discovery. Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation. Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes: * Concepts and terms of combinatorial chemistry * Polymer-supported synthesis of organic compounds * Macro beads as microreactors * Solid-phase methods in combinatorial chemistry * Encoded combinatorial libraries, including Rf-encoding of synthesis beads * Strategies for combinatorial libraries of oligosaccharides * Combinatorial libraries of peptides, proteins, and antibodies using biological systems. While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.

Natural Products Chemistry III

Author : T.I. Atta-ur-Rahman,Philip W. Le Quesne
Publisher : Springer Science & Business Media
Page : 369 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642740176

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Natural Products Chemistry III by T.I. Atta-ur-Rahman,Philip W. Le Quesne Pdf

Natural product chemistry has undergone an explosive growth during the latter half of the current century. This has been brought about by a number of factors. One of these has been the growing number of sub stances from natural sources which display interesting pharmacological activities. These include antibiotics, anti-tumor agents, immunostimu lants, drugs affecting the cardiovascular and central nervous systems, analgesics etc. Another factor has been the improvements made in the technology of isolation processes which includes the development of such techniques as high pressure liquid chromatography which has al lowed the rapid isolation of substances which were previously diffi cult to obtain by classical procedures. The most important factor has been the development of new spectrosopic techniques which have opened up whole new vistas in this exciting field. Prominent in these advan ces has been the advent of powerful superconducting magnets with very stable magnetic fields, and pulse NMR in which the duration, direction and phases of pulses can be accurately controlled by means of mini computers. These have heralded the advent of two-dimensional NMR spec troscopy which has now come to be routinely employed in unravelling complex structures. No less important, though somewhat less dramatic, have been the advances made in the field of mass spectroscopy where new ionization techniques such as positive and negative fast atom bom bardment, field desorption, chemical ionization etc. have allowed the mass spectra of larger non-volatile substances to be recorded. The field of organic synthesis has seen equally rapid advances.

Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products

Author : Anonim
Publisher : Springer Science & Business Media
Page : 262 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783709163313

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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products by Anonim Pdf

The volumes of this classic series, now referred to simply as "Zechmeister” after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series’ inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.