Author : Andrew G. Stephen
Publisher : Springer Nature
Page : 366 pages
File Size : 43,7 Mb
Release : 2024-06-03
Category : Electronic
ISBN : 9781071638224
KRAS
Andrew G. Stephen
Kras
Kras Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Kras book. This book definitely worth reading, it is an incredibly well-written.
Machine learning for biological sequence analysis
Quan Zou,Zhibin Lv
Author : Quan Zou,Zhibin Lv
Publisher : Frontiers Media SA
Page : 150 pages
File Size : 45,8 Mb
Release : 2023-03-09
Category : Science
ISBN : 9782832516010
Machine learning for biological sequence analysis by Quan Zou,Zhibin Lv Pdf
Journal of the National Cancer Institute
Anonim
Author : Anonim
Publisher : Unknown
Page : 1202 pages
File Size : 40,9 Mb
Release : 2000
Category : Cancer
ISBN : RUTGERS:43008001133562
Journal of the National Cancer Institute by Anonim Pdf
Ras and Cancer in the 21st Century
Linda VanAelst,Frank McCormick
Author : Linda VanAelst,Frank McCormick
Publisher : Perspectives Cshl
Page : 300 pages
File Size : 52,7 Mb
Release : 2018
Category : Medical
ISBN : 1621822214
Ras and Cancer in the 21st Century by Linda VanAelst,Frank McCormick Pdf
Ras proteins are key molecular switches in cell signaling pathways that, when activated, trigger cell growth and division. Mutations that produce abnormally active Ras proteins are common in human cancers, particularly those of the pancreas, lung, and colon. These cancers can be difficult to treat because Ras oncoproteins have long been considered 'undruggable.' Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the recent progress that has been made in understanding Ras biology, how Ras activation leads to tumorigenesis, and ways in which oncogenic Ras signaling may be targeted therapeutically. The contributors review the biochemical characteristics of the different Ras isoforms (HRAS, KRAS, and NRAS), their main effectors and signaling pathways, and the mutations that lead to their constitutive activation. Recent work showing that some Ras oncoproteins may be effectively inhibited by small molecules is covered, as is work on alternative targets (e.g., enzymes that catalyze posttranslational modifications of Ras) and inhibitors (e.g., nucleic acids). The authors also discuss how organoids and mouse models are being used to study tumor progression and therapeutic efficacy. This volume is therefore essential reading for all cancer biologists, cell and molecular biologists, and pharmacologists concerned with understanding and treating Ras-driven cancers.
AACR 2017 Proceedings: Abstracts 1-3062
American Association for Cancer Research
Author : American Association for Cancer Research
Publisher : CTI Meeting Technology
Page : 128 pages
File Size : 47,6 Mb
Release : 2017-03-13
Category : Medical
ISBN : 8210379456XXX
AACR 2017 Proceedings: Abstracts 1-3062 by American Association for Cancer Research Pdf
The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.
Effects of Expression of Mutant Kras on Pancreatic Epithelium in Vivo
Paul J. Grippo
Author : Paul J. Grippo
Publisher : Unknown
Page : 224 pages
File Size : 42,5 Mb
Release : 2000
Category : Electronic
ISBN : WISC:89075189290
Effects of Expression of Mutant Kras on Pancreatic Epithelium in Vivo by Paul J. Grippo Pdf
Handbook of Therapeutic Biomarkers in Cancer
Sherry X. Yang,Janet E. Dancey
Author : Sherry X. Yang,Janet E. Dancey
Publisher : CRC Press
Page : 678 pages
File Size : 46,7 Mb
Release : 2021-02-01
Category : Medical
ISBN : 9781000367515
Handbook of Therapeutic Biomarkers in Cancer by Sherry X. Yang,Janet E. Dancey Pdf
This book provides a comprehensive overview of the fast-evolving subject of clinical application of cancer therapeutic biomarkers. The second edition captures significant progress of cancer immunotherapy and emphasizes the genetic basis for selective cancer treatment. It covers an in-depth insight on biomarkers across a broad area of cancer research and oncology with a wealth of integrated genetic and molecular information about specific therapies by a multidisciplinary team of internationally recognized experts. Each chapter focuses on a class of targeted, immunologic, or chemotherapy agents and their companion biomarkers that predict response, benefit or resistance, and severe adverse event. The book will serve as a handbook for health professionals and scientists on the current applicable biomarkers in the management of cancer. The vision into the systemic classification and statistical consideration of therapeutic biomarkers summarized by the book editors and chapter authors will help advance precision medicine—a precisely tailored cancer treatment strategy for cancer patient care.
SPEC - Contemporary Management of Metastatic Colorectal Cancer
Aslam Ejaz,Timothy M. Pawlik
Author : Aslam Ejaz,Timothy M. Pawlik
Publisher : Academic Press
Page : 328 pages
File Size : 43,8 Mb
Release : 2022-06-23
Category : Computers
ISBN : 9780323985680
SPEC - Contemporary Management of Metastatic Colorectal Cancer by Aslam Ejaz,Timothy M. Pawlik Pdf
Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach summarizes current knowledge and provides evidenced-based practice recommendations on how to treat patients with metastatic colorectal cancer. The book presents topics such as pre-operating imaging, the use of molecular markers in treatment decisions, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. In addition, it discusses immunotherapy, targeted therapies and survivorship. This is a valuable resource for practitioners, cancer researchers, oncologists, graduate students and members of biomedical research who need to understand more about novel treatments for colorectal cancer metastasis. Summarizes contemporary data in the workup and treatment of patients with metastatic colorectal cancer Discusses novel patient-centric personalized approaches surrounding the management of such cancer types Presents evidenced-based recommendations for precision care among patients with metastatic colorectal cancer
Therapeutic Targeting of RAS Mutant Cancers
Edward C. Stites,Kendra Paskvan,Shumei Kato
Author : Edward C. Stites,Kendra Paskvan,Shumei Kato
Publisher : Cambridge University Press
Page : 59 pages
File Size : 48,9 Mb
Release : 2022-09-15
Category : Medical
ISBN : 9781009081023
Therapeutic Targeting of RAS Mutant Cancers by Edward C. Stites,Kendra Paskvan,Shumei Kato Pdf
The KRAS oncogene is believed to be the most common single nucleotide variant oncogene in human cancer. Historically, efforts to target KRAS and the other RAS GTPases have struggled. More recently, efforts have focused on identifying and exploiting features unique to specific oncogenic mutations. This has led to the first FDA approval for a RAS targeted therapy. This new agent is a covalent inhibitor that reacts with the cysteine residue created by a codon 12 glycine to cysteine (G12C) mutation within KRAS. Mutant-specific strategies may also exist for other KRAS single nucleotide variants, and recent studies provide examples and mechanisms.
Software Engineering and Formal Methods
Carlos Canal,Akram Idani
Author : Carlos Canal,Akram Idani
Publisher : Springer
Page : 405 pages
File Size : 48,9 Mb
Release : 2015-01-31
Category : Computers
ISBN : 9783319152011
Software Engineering and Formal Methods by Carlos Canal,Akram Idani Pdf
This book constitutes revised selected papers from the workshops collocated with the SEFM 2014 conference on Software Engineering and Formal Methods, held in Grenoble, France, in September 2014. The 26 papers included in this volume were carefully reviewed and selected from 49 submissions. They are from the following workshops: the 1st Workshop on Human-Oriented Formal Methods - From Readability to Automation, HOFM 2014, the 3rd International Symposium on Modelling and Knowledge Management Applications - Systems and Domains, MoKMaSD 2014, the 8th International Workshop on Foundations and Techniques for Open Source Software Certification, Open Cert 2014, the 1st Workshop on Safety and Formal Methods, SaFoMe 2014 and the 4th Workshop on Formal Methods in the Development of Software, WS-FMDS 2014.
365 Days of progress in cancer molecular targets and therapeutics
Wafik S. El-Deiry,Massimo Broggini
Author : Wafik S. El-Deiry,Massimo Broggini
Publisher : Frontiers Media SA
Page : 320 pages
File Size : 46,5 Mb
Release : 2023-09-26
Category : Medical
ISBN : 9782832534342
365 Days of progress in cancer molecular targets and therapeutics by Wafik S. El-Deiry,Massimo Broggini Pdf
Lung Cancer Therapy Annual 7
Rolf A. Stahel
Author : Rolf A. Stahel
Publisher : CRC Press
Page : 186 pages
File Size : 53,8 Mb
Release : 2012-08-13
Category : Medical
ISBN : 9781841848679
Lung Cancer Therapy Annual 7 by Rolf A. Stahel Pdf
Oncology research and practice in lung cancer continues to develop rapidly. This latest edition of Lung Cancer Therapy Annual briefs the oncology community with a review of the recent literature, emphasizing the therapeutic aspects. It offers an update of the impact that this information will have on the day-to-day management of the lung cancer patient. New to the Seventh Edition: An update of the impact of recent developments will have on day-to-day management of lung cancer patients Four new chapters on the treatment of non-small cell lung cancer (NSCLC) A new chapter on thymoma Additional topics include: Oncogenic driver mutations First line therapy of advanced non-small cell lung cancer without activating EGFR mutation Second line therapy of non-small cell lung cancer Adjunct and neoadjunct therapy of non-small cell lung cancer Advances in surgery of lung cancer; advances in radiotherapy of lung cancer Mesothelioma Thymic tumors
Tumor Board Review
Robert F. Todd,Kathleen A. Cooney, MD
Author : Robert F. Todd,Kathleen A. Cooney, MD
Publisher : Demos Medical Publishing
Page : 377 pages
File Size : 46,9 Mb
Release : 2011-10-19
Category : Medical
ISBN : 9781936287178
Tumor Board Review by Robert F. Todd,Kathleen A. Cooney, MD Pdf
Tumor Board Reviews provides comprehensive coverage of all topics in oncology. Each of the 32 chapters focuses on a specific major disease. A brief overview of epidemiology and risk factors is followed by a sequence of specific presentations organized by tumors stage or disease classification. Each discussion features a case presentation that mimics the format of a tumor board presentation and thus illustrates key diagnostic and management decisions. There is also a discussion of the evidence that supports the clinical management decisions taken in the case, based on current expert panel guidelines. Algorithms and decision tree graphics are used extensively to provide visual support of the decision process. The combination of case presentations and evidence-based management discussions make this volume a unique tool for keeping current with clinical guidelines and provides the reader with a clear understanding of applications of new information for use in daily practice.
Rectal Cancer: New Insights for the Healthcare Professional: 2012 Edition
Anonim
Author : Anonim
Publisher : ScholarlyEditions
Page : 98 pages
File Size : 43,9 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464972676
Rectal Cancer: New Insights for the Healthcare Professional: 2012 Edition by Anonim Pdf
Rectal Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Rectal Cancer in a concise format. The editors have built Rectal Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Rectal Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Rectal Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Lung Cancer, An Issue of Hematology/Oncology Clinics, E-Book
Roy S. Herbst,Daniel Morgensztern
Author : Roy S. Herbst,Daniel Morgensztern
Publisher : Elsevier Health Sciences
Page : 249 pages
File Size : 47,7 Mb
Release : 2016-12-03
Category : Medical
ISBN : 9780323496605
Lung Cancer, An Issue of Hematology/Oncology Clinics, E-Book by Roy S. Herbst,Daniel Morgensztern Pdf
This issue of Hematology/Oncology Clinics will focus on lung cancer; specifically, Genomics in lung cancer; Neoadjuvant and adjuvant therapy for NSCLC; Treatment of locally advanced NSCLC; First line systemic therapy for NSCLC; Second line chemotherapy and beyond for NSCLC; Treatment of EGFR mutant tumors; Treatment of ALK positive tumors; New targets in NSCLC; Immunotherapy; Advances in Small cell lung cancer; and many more!