Laser Photodissociation And Spectroscopy Of Mass Separated Biomolecular Ions

Author : Nicolas C. Polfer,Philippe Dugourd
Publisher : Springer Science & Business Media
Page : 119 pages
File Size : 53,9 Mb
Release : 2013-09-03
Category : Science
ISBN : 9783319012520

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Laser Photodissociation and Spectroscopy of Mass-separated Biomolecular Ions by Nicolas C. Polfer,Philippe Dugourd Pdf

This lecture notes book presents how enhanced structural information of biomolecular ions can be obtained from interaction with photons of specific frequency - laser light. The methods described in the book "Laser photodissociation and spectroscopy of mass-separated biomolecular ions" make use of the fact that the discrete energy and fast time scale of photoexcitation can provide more control in ion activation. This activation is the crucial process producing structure-informative product ions that cannot be generated with more conventional heating methods, such as collisional activation. The book describes how the powerful separation capabilities and sensitivity of mass spectrometry (MS) can be combined with the structural insights from spectroscopy by measuring vibrational and electronic spectra of trapped analytes. The implementation of laser-based photodissociation techniques in MS requires basic knowledge of tunable light sources and ion trapping devices. This book introduces the reader to key concepts and approaches in molecular spectroscopy, and the light sources and ion traps employed in such experiments. The power of the methods is demonstrated by spectroscopic interrogation of a range of important biomolecular systems, including peptides, proteins, and saccharides, with laser light in the ultraviolet-visible, and infrared range. The book "Laser photodissociation and spectroscopy of mass-separated biomolecular ions" is an indispensable resource for students and researchers engaged or interested in this emerging field. It provides the solid background of key concepts and technologies for the measurements, discusses state-of-the-art experiments, and provides an outlook on future developments and applications.

Author : Frank Sobott,Alison E. Ashcroft
Publisher : Royal Society of Chemistry
Page : 547 pages
File Size : 49,8 Mb
Release : 2021-11-26
Category : Science
ISBN : 9781839161667

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Ion Mobility-Mass Spectrometry by Frank Sobott,Alison E. Ashcroft Pdf

Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and will help the end users understand the practicalities of using different instruments for different ion mobility purposes.

Author : Bauer, Sebastian
Publisher : KIT Scientific Publishing
Page : 236 pages
File Size : 44,6 Mb
Release : 2018-07-18
Category : Technology & Engineering
ISBN : 9783731507888

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Hyperspectral Image Unmixing Incorporating Adjacency Information by Bauer, Sebastian Pdf

While the spectral information contained in hyperspectral images is rich, the spatial resolution of such images is in many cases very low. Many pixel spectra are mixtures of pure materials' spectra and therefore need to be decomposed into their constituents. This work investigates new decomposition methods taking into account spectral, spatial and global 3D adjacency information. This allows for faster and more accurate decomposition results.

Author : David M. Lubman
Publisher : Oxford University Press on Demand
Page : 560 pages
File Size : 43,5 Mb
Release : 1990
Category : Science
ISBN : 9780195059298

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Lasers and Mass Spectrometry by David M. Lubman Pdf

Contributors to this volume focus on the fundamentals of the technique of analyzing material based on the atomic weight of the species, using the power and definition of lasers to enable measurement of smaller quantities and more finely localized particles. Each chapter deals with a particular application area and should be sufficient to form an entry point for the utilization of mass spectrometry by graduate students and researchers. The book provides the first full discussion of the new techniques of laser applications in the field.

Author : Lydia Marie Nuwaysir
Publisher : Unknown
Page : 468 pages
File Size : 54,9 Mb
Release : 1990
Category : Dissociation
ISBN : UCR:31210008499152

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Developments in Laser Desorption and Photodissociation Fourier Transform Mass Spectrometry by Lydia Marie Nuwaysir Pdf

Author : Anouk M. Rijs,Jos Oomens
Publisher : Springer
Page : 406 pages
File Size : 41,9 Mb
Release : 2015-06-03
Category : Science
ISBN : 9783319192048

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Gas-Phase IR Spectroscopy and Structure of Biological Molecules by Anouk M. Rijs,Jos Oomens Pdf

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Author : Hai-Lung Dai,Wilson Ho
Publisher : World Scientific
Page : 824 pages
File Size : 52,9 Mb
Release : 1995
Category : Laser spectroscopy
ISBN : 9810229976

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Laser Spectroscopy and Photochemistry on Metal Surfaces by Hai-Lung Dai,Wilson Ho Pdf

Author : Martina Knoop,Niels Madsen,Richard C Thompson
Publisher : World Scientific
Page : 376 pages
File Size : 42,6 Mb
Release : 2014-01-06
Category : Science
ISBN : 9781783264070

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Physics with Trapped Charged Particles by Martina Knoop,Niels Madsen,Richard C Thompson Pdf

This book is a collection of articles on Physics with Trapped Charged Particles by speakers at the Les Houches Winter School. The articles cover all types of physics with charged particles, and are aimed at introducing the basic issues at hand, as well as the latest developments in the field. It is appropriate for PhD students and early career researchers, or interested parties new to the area. Contents:Physics with Trapped Charged Particles (M Knoop, N Madsen and R C Thompson)Detection Techniques for Trapped Ions (M Knoop)Cooling Techniques for Trapped Ions (D M Segal and Ch Wunderlich)Accumulation, Storage and Manipulation of Large Numbers of Positrons in Traps I — The Basics (C M Surko)Accumulation, Storage and Manipulation of Large Numbers of Positrons in Traps II — Selected Topics (C M Surko, J R Danielson and T R Weber)Waves in Non-neutral Plasma (F Anderegg)Internal Transport in Non-neutral Plasma (F Anderegg)Antihydrogen Formation and Trapping (N Madsen)Quantum Information Processing with Trapped Ions (C F Roos)Optical Atomic Clocks in Ion Traps (H S Margolis)Novel Penning Traps (J Verdú)Trapped Electrons as Electrical (Quantum) Circuits (J Verdú) Readership: University and college students undertaking mechanical, aerospace, electromechanical, engineering or applied mechanics programs. Key Features:Gives a basic overview of this new, vibrant area of researchGives a good introduction to the key issues in physics of this fieldContains contributions from researchers at the forefront of the fieldKeywords:Charged Particles;Particle Traps;Non-Neutral Plasma;Quantum Information;Penning Trap;Paul Trap;Rotating Wall;Laser Cooling;RF Trap;Atomic Clock

Author : Matthew Francis Bush
Publisher : Unknown
Page : 746 pages
File Size : 43,8 Mb
Release : 2008
Category : Electronic
ISBN : UCAL:C3481456

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Infrared Spectroscopy of Hydrated and Biomolecular Ions by Matthew Francis Bush Pdf

Author : Jeroen Kool,Wilfried M. A. Niessen
Publisher : John Wiley & Sons
Page : 402 pages
File Size : 53,7 Mb
Release : 2015-05-04
Category : Science
ISBN : 9783527334643

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Analyzing Biomolecular Interactions by Mass Spectrometry by Jeroen Kool,Wilfried M. A. Niessen Pdf

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Author : Chhabil Dass
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 48,9 Mb
Release : 2007-05-11
Category : Science
ISBN : 9780470118481

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Fundamentals of Contemporary Mass Spectrometry by Chhabil Dass Pdf

Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

Author : Edmond de Hoffmann,Vincent Stroobant
Publisher : Wiley
Page : 420 pages
File Size : 48,5 Mb
Release : 2001-10-10
Category : Science
ISBN : 0471485659

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Mass Spectrometry by Edmond de Hoffmann,Vincent Stroobant Pdf

Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Author : J. Throck Watson,O. David Sparkman
Publisher : John Wiley & Sons
Page : 864 pages
File Size : 54,7 Mb
Release : 2013-07-09
Category : Science
ISBN : 9781118681589

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Introduction to Mass Spectrometry by J. Throck Watson,O. David Sparkman Pdf

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Author : Anonim
Publisher : Unknown
Page : 1224 pages
File Size : 50,5 Mb
Release : 1993
Category : Medicine
ISBN : MINN:31951P002070725

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Biomedical Index to PHS-supported Research by Anonim Pdf

Author : Gary Siuzdak
Publisher : Elsevier
Page : 179 pages
File Size : 55,6 Mb
Release : 1996-02-12
Category : Science
ISBN : 9780080535845

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Mass Spectrometry for Biotechnology by Gary Siuzdak Pdf

If you investigate biological systems and might use mass spectrometry in your research but need to know more about it, this book is for you. It introduces the fundamental concepts of mass spectrometry and how mass spectrometers work. It also presents recent advancements particularly interesting to bio-researchers in an easy-to-understand manner that does not require extensive background in chemistry, math, or physics. Glossary of basic terms Abundant illustrations Examples of applications Practical tips on using mass spectrometric techniques Useful for peptide, protein, oligonucleotide, and carbohydrate analysis Simplified description of mass spectrometry including: Matrix-Assisted Laser Desorption/Ionization (MALDI) Electrospray Ionization (ESI) Fast Atom/Ion Bombardment (FAB)